8DCP
 
 | | PI 3-kinase alpha with nanobody 3-126 | | 分子名称: | Phosphatidylinositol 3-kinase regulatory subunit alpha, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform | | 著者 | Hart, J.R, Liu, X, Pan, C, Liang, A, Ueno, L, Xu, Y, Quezada, A, Zou, X, Yang, S, Zhou, Q, Schoonooghe, S, Hassanzadeh-Ghassabeh, G, Xia, T, Shui, W, Yang, D, Vogt, P.K, Wang, M.-W. | | 登録日 | 2022-06-17 | | 公開日 | 2022-09-21 | | 実験手法 | ELECTRON MICROSCOPY (2.41 Å) | | 主引用文献 | Nanobodies and chemical cross-links advance the structural and functional analysis of PI3K alpha.
Proc.Natl.Acad.Sci.USA, 119, 2022
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8DCX
 | | PI 3-kinase alpha with nanobody 3-159 | | 分子名称: | Phosphatidylinositol 3-kinase regulatory subunit alpha, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform | | 著者 | Hart, J.R, Liu, X, Pan, C, Liang, A, Ueno, L, Xu, Y, Quezada, A, Zou, X, Yang, S, Zhou, Q, Schoonooghe, S, Hassanzadeh-Ghassabeh, G, Xia, T, Shui, W, Yang, D, Vogt, P.K, Wang, M.-W. | | 登録日 | 2022-06-17 | | 公開日 | 2022-09-21 | | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | | 主引用文献 | Nanobodies and chemical cross-links advance the structural and functional analysis of PI3K alpha.
Proc.Natl.Acad.Sci.USA, 119, 2022
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5JO7
 | | Henbane premnaspirodiene synthase (HPS), also known as Henbane vetispiradiene synthase (HVS) from Hyoscyamus muticus | | 分子名称: | Vetispiradiene synthase 1 | | 著者 | Koo, H.J, Xu, Y, Louie, G.V, Bowman, M, Noel, J.P. | | 登録日 | 2016-05-02 | | 公開日 | 2017-05-03 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | Functional study of terpene synthase from 512 mutant library of henbane premnaspirodiene synthase reveals protein residue interactions
To Be Published
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3J3T
 | | Structural dynamics of the MecA-ClpC complex revealed by cryo-EM | | 分子名称: | Adapter protein MecA 1, Negative regulator of genetic competence ClpC/MecB | | 著者 | Liu, J, Mei, Z, Li, N, Qi, Y, Xu, Y, Shi, Y, Wang, F, Lei, J, Gao, N. | | 登録日 | 2013-04-18 | | 公開日 | 2013-05-15 | | 最終更新日 | 2024-03-20 | | 実験手法 | ELECTRON MICROSCOPY (9 Å) | | 主引用文献 | Structural dynamics of the MecA-ClpC complex: a type II AAA+ protein unfolding machine.
J.Biol.Chem., 288, 2013
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3J3R
 | | Structural dynamics of the MecA-ClpC complex revealed by cryo-EM | | 分子名称: | Adapter protein MecA 1, Negative regulator of genetic competence ClpC/MecB | | 著者 | Liu, J, Mei, Z, Li, N, Qi, Y, Xu, Y, Shi, Y, Wang, F, Lei, J, Gao, N. | | 登録日 | 2013-04-18 | | 公開日 | 2013-05-15 | | 最終更新日 | 2024-03-20 | | 実験手法 | ELECTRON MICROSCOPY (9.4 Å) | | 主引用文献 | Structural dynamics of the MecA-ClpC complex: a type II AAA+ protein unfolding machine
J.Biol.Chem., 288, 2013
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3J3U
 | | Structural dynamics of the MecA-ClpC complex revealed by cryo-EM | | 分子名称: | Adapter protein MecA 1, Negative regulator of genetic competence ClpC/MecB | | 著者 | Liu, J, Mei, Z, Li, N, Qi, Y, Xu, Y, Shi, Y, Wang, F, Lei, J, Gao, N. | | 登録日 | 2013-04-18 | | 公開日 | 2013-05-15 | | 最終更新日 | 2024-03-20 | | 実験手法 | ELECTRON MICROSCOPY (10 Å) | | 主引用文献 | Structural dynamics of the MecA-ClpC complex: a type II AAA+ protein unfolding machine.
J.Biol.Chem., 288, 2013
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3J3S
 | | Structural dynamics of the MecA-ClpC complex revealed by cryo-EM | | 分子名称: | Adapter protein MecA 1, Negative regulator of genetic competence ClpC/MecB | | 著者 | Liu, J, Mei, Z, Li, N, Qi, Y, Xu, Y, Shi, Y, Wang, F, Lei, J, Gao, N. | | 登録日 | 2013-04-18 | | 公開日 | 2013-05-15 | | 最終更新日 | 2024-03-20 | | 実験手法 | ELECTRON MICROSCOPY (11 Å) | | 主引用文献 | Structural dynamics of the MecA-ClpC complex: a type II AAA+ protein unfolding machine.
J.Biol.Chem., 288, 2013
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2E4I
 | | Human Telomeric DNA mixed-parallel/antiparallel quadruplex under Physiological Ionic Conditions Stabilized by Proper Incorporation of 8-Bromoguanosines | | 分子名称: | DNA (5'-D(*DAP*(BGM)P*DGP*DGP*DTP*DTP*DAP*(BGM)P*DGP*DGP*DTP*DTP*DAP*(BGM)P*(BGM)P*DGP*DTP*DTP*DAP*(BGM)P*DGP*DG)-3') | | 著者 | Matsugami, A, Xu, Y, Noguchi, Y, Sugiyama, H, Katahira, M. | | 登録日 | 2006-12-11 | | 公開日 | 2007-12-11 | | 最終更新日 | 2024-05-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structure of a human telomeric DNA sequence stabilized by 8-bromoguanosine substitutions, as determined by NMR in a K+ solution
Febs J., 274, 2007
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1HIY
 | | Binding of nucleotides to NDP kinase | | 分子名称: | 3'-DEOXY 3'-AMINO ADENOSINE-5'-DIPHOSPHATE, NUCLEOSIDE DIPHOSPHATE KINASE | | 著者 | Cervoni, L, Lascu, I, Xu, Y, Gonin, P, Morr, M, Merouani, M, Janin, J, Giartoso, A. | | 登録日 | 2001-01-05 | | 公開日 | 2001-05-31 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Binding of Nucleotides to Nucleoside Diphosphate Kinase: A Calorimetric Study.
Biochemistry, 40, 2001
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1KSB
 | | Relationship of Solution and Protein-Bound Structures of DNA Duplexes with the Major Intrastrand Cross-Link Lesions Formed on Cisplatin Binding to DNA | | 分子名称: | 5'-D(*AP*GP*GP*CP*CP*GP*GP*AP*G)-3', 5'-D(*CP*TP*CP*CP*GP*GP*CP*CP*T)-3', Cisplatin | | 著者 | Marzilli, L.G, Saad, J.S, Kuklenyik, Z, Keating, K.A, Xu, Y. | | 登録日 | 2002-01-11 | | 公開日 | 2002-01-17 | | 最終更新日 | 2024-05-01 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Relationship of solution and protein-bound structures of DNA duplexes with the major intrastrand cross-link lesions formed on cisplatin binding to DNA.
J.Am.Chem.Soc., 123, 2001
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8IBV
 | | Cryo-EM structure of the motilin-bound motilin receptor-Gq protein complex | | 分子名称: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(q) subunit alpha, ... | | 著者 | Jiang, Y, Xu, H.E, You, C, Xu, Y. | | 登録日 | 2023-02-10 | | 公開日 | 2023-04-12 | | 実験手法 | ELECTRON MICROSCOPY (3.19 Å) | | 主引用文献 | Structural basis for motilin and erythromycin recognition by motilin receptor.
Sci Adv, 9, 2023
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8IBU
 | | Cryo-EM structure of the erythromycin-bound motilin receptor-Gq protein complex | | 分子名称: | ERYTHROMYCIN A, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | | 著者 | You, C, Jiang, Y, Xu, H.E, Xu, Y. | | 登録日 | 2023-02-10 | | 公開日 | 2023-04-12 | | 最終更新日 | 2024-05-29 | | 実験手法 | ELECTRON MICROSCOPY (3.51 Å) | | 主引用文献 | Structural basis for motilin and erythromycin recognition by motilin receptor.
Sci Adv, 9, 2023
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1LEO
 | | P100S NUCLEOSIDE DIPHOSPHATE KINASE | | 分子名称: | NUCLEOSIDE DIPHOSPHATE KINASE | | 著者 | Janin, J, Xu, Y, Veron, M. | | 登録日 | 1996-05-22 | | 公開日 | 1996-11-08 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Nucleoside diphosphate kinase. Investigation of the intersubunit contacts by site-directed mutagenesis and crystallography.
J.Biol.Chem., 271, 1996
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1MOT
 | | NMR Structure Of Extended Second Transmembrane Domain Of Glycine Receptor alpha1 Subunit in SDS Micelles | | 分子名称: | Glycine Receptor alpha-1 CHAIN | | 著者 | Yushmanov, V.E, Mandal, P.K, Liu, Z, Tang, P, Xu, Y. | | 登録日 | 2002-09-09 | | 公開日 | 2003-09-23 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | NMR Structure and Backbone Dynamics of the Extended Second Transmembrane Domain of the Human Neuronal Glycine Receptor Alpha1 Subunit
Biochemistry, 42, 2003
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1NHL
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3NMH
 | | Crystal structure of the abscisic receptor PYL2 in complex with pyrabactin | | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, 4-bromo-N-(pyridin-2-ylmethyl)naphthalene-1-sulfonamide, Abscisic acid receptor PYL2 | | 著者 | Zhou, X.E, Melcher, K, Ng, L.-M, Soon, F.-F, Xu, Y, Suino-Powell, K.M, Kovach, A, Li, J, Yong, E.-L, Xu, H.E. | | 登録日 | 2010-06-22 | | 公開日 | 2010-08-25 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Identification and mechanism of ABA receptor antagonism.
Nat.Struct.Mol.Biol., 17, 2010
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3NMV
 | | Crystal structure of pyrabactin-bound abscisic acid receptor PYL2 mutant A93F in complex with type 2C protein phosphatase ABI2 | | 分子名称: | 4-bromo-N-(pyridin-2-ylmethyl)naphthalene-1-sulfonamide, Abscisic acid receptor PYL2, MAGNESIUM ION, ... | | 著者 | Zhou, X.E, Melcher, K, Ng, L.-M, Soon, F.-F, Xu, Y, Suino-Powell, K.M, Kovach, A, Li, J, Yong, E.-L, Xu, H.E. | | 登録日 | 2010-06-22 | | 公開日 | 2010-08-25 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Identification and mechanism of ABA receptor antagonism.
Nat.Struct.Mol.Biol., 17, 2010
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3NMN
 | | Crystal structure of pyrabactin-bound abscisic acid receptor PYL1 in complex with type 2C protein phosphatase ABI1 | | 分子名称: | 4-bromo-N-(pyridin-2-ylmethyl)naphthalene-1-sulfonamide, Abscisic acid receptor PYL1, MAGNESIUM ION, ... | | 著者 | Zhou, X.E, Melcher, K, Ng, L.-M, Soon, F.-F, Xu, Y, Suino-Powell, K.M, Kovach, A, Li, J, Yong, E.-L, Xu, H.E. | | 登録日 | 2010-06-22 | | 公開日 | 2010-08-25 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | Identification and mechanism of ABA receptor antagonism.
Nat.Struct.Mol.Biol., 17, 2010
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3NK7
 | | Structure of the Nosiheptide-resistance methyltransferase S-adenosyl-L-methionine Complex | | 分子名称: | 23S rRNA methyltransferase, S-ADENOSYLMETHIONINE | | 著者 | Yang, H, Wang, Z, Shen, Y, Wang, P, Murchie, A, Xu, Y. | | 登録日 | 2010-06-18 | | 公開日 | 2010-07-21 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Crystal Structure of the Nosiheptide-Resistance Methyltransferase of Streptomyces actuosus
Biochemistry, 49, 2010
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3NMP
 | | Crystal structure of the abscisic receptor PYL2 mutant A93F in complex with pyrabactin | | 分子名称: | 4-bromo-N-(pyridin-2-ylmethyl)naphthalene-1-sulfonamide, Abscisic acid receptor PYL2 | | 著者 | Zhou, X.E, Melcher, K, Ng, L.-M, Soon, F.-F, Xu, Y, Suino-Powell, K.M, Kovach, A, Li, J, Yong, E.-L, Xu, H.E. | | 登録日 | 2010-06-22 | | 公開日 | 2010-08-25 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Identification and mechanism of ABA receptor antagonism.
Nat.Struct.Mol.Biol., 17, 2010
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3NMT
 | | Crystal structure of pyrabactin bound abscisic acid receptor PYL2 mutant A93F in complex with type 2C protein phosphatase HAB1 | | 分子名称: | 4-bromo-N-(pyridin-2-ylmethyl)naphthalene-1-sulfonamide, Abscisic acid receptor PYL2, MAGNESIUM ION, ... | | 著者 | Zhou, X.E, Melcher, K, Ng, L.-M, Soon, F.-F, Xu, Y, Suino-Powell, K.M, Kovach, A, Li, J, Yong, E.-L, Xu, H.E. | | 登録日 | 2010-06-22 | | 公開日 | 2010-08-25 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.56 Å) | | 主引用文献 | Identification and mechanism of ABA receptor antagonism.
Nat.Struct.Mol.Biol., 17, 2010
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3NK6
 | | Structure of the Nosiheptide-resistance methyltransferase | | 分子名称: | 23S rRNA methyltransferase | | 著者 | Yang, H, Wang, Z, Shen, Y, Wang, P, Murchie, A, Xu, Y. | | 登録日 | 2010-06-18 | | 公開日 | 2010-07-21 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Crystal Structure of the Nosiheptide-Resistance Methyltransferase of Streptomyces actuosus
Biochemistry, 49, 2010
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2XI4
 | | Torpedo californica Acetylcholinesterase in Complex with Aflatoxin B1 (Orthorhombic Space Group) | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETYLCHOLINESTERASE, AFLATOXIN B1, ... | | 著者 | Sanson, B, Colletier, J.P, Xu, Y, Lang, P.T, Jiang, H, Silman, I, Sussman, J.L, Weik, M. | | 登録日 | 2010-06-28 | | 公開日 | 2011-03-23 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Backdoor Opening Mechanism in Acetylcholinesterase Based on X-Ray Crystallography and Molecular Dynamics Simulations.
Protein Sci., 20, 2011
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8HK5
 | | C5aR1-Gi-C5a protein complex | | 分子名称: | C5a anaphylatoxin chemotactic receptor 1, Complement C5, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | | 著者 | Wang, Y, Liu, W, Xu, Y, Zhuang, Y, Xu, H.E. | | 登録日 | 2022-11-24 | | 公開日 | 2023-05-10 | | 最終更新日 | 2023-11-08 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | Revealing the signaling of complement receptors C3aR and C5aR1 by anaphylatoxins.
Nat.Chem.Biol., 19, 2023
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8HK3
 | | C3aR-Gi-apo protein complex | | 分子名称: | C3a anaphylatoxin chemotactic receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | | 著者 | Wang, Y, Liu, W, Xu, Y, Zhuang, Y, Xu, H.E. | | 登録日 | 2022-11-24 | | 公開日 | 2023-05-10 | | 最終更新日 | 2023-11-08 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Revealing the signaling of complement receptors C3aR and C5aR1 by anaphylatoxins.
Nat.Chem.Biol., 19, 2023
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