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7FHM
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BU of 7fhm by Molmil
Crystal structure of an orphan heme uptake protein (MhuP) of ABC transporter from Mycobacterium tuberculosis (Form I)
分子名称: 1,2-ETHANEDIOL, ACETATE ION, CARBON DIOXIDE, ...
著者Mandal, S.K, Kanaujia, S.P.
登録日2021-07-29
公開日2022-06-01
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Role of an orphan substrate-binding protein MhuP in transient heme transfer in Mycobacterium tuberculosis
Int.J.Biol.Macromol., 211, 2022
7CA2
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BU of 7ca2 by Molmil
ENGINEERING THE HYDROPHOBIC POCKET OF CARBONIC ANHYDRASE II
分子名称: CARBONIC ANHYDRASE II, MERCURY (II) ION, ZINC ION
著者Nair, S.K, Christianson, D.W.
登録日1991-07-09
公開日1992-07-15
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Engineering the hydrophobic pocket of carbonic anhydrase II.
Biochemistry, 30, 1991
7C1I
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BU of 7c1i by Molmil
Crystal structure of histidine-containing phosphotransfer protein B (HptB) from Pseudomonas aeruginosa PAO1
分子名称: Histidine kinase
著者Chen, S.K, Guan, H.H, Wu, P.H, Lin, L.T, Wu, M.C, Chang, H.Y, Chen, N.C, Lin, C.C, Chuankhayan, P, Huang, Y.C, Lin, P.J, Chen, C.J.
登録日2020-05-04
公開日2020-11-04
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (1.58 Å)
主引用文献Structural insights into the histidine-containing phospho-transfer protein and receiver domain of sensor histidine kinase suggest a complex model in the two-component regulatory system in Pseudomonas aeruginosa
Iucrj, 7, 2020
7K5J
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BU of 7k5j by Molmil
Structure of an E1-E2-ubiquitin thioester mimetic
分子名称: ADENOSINE MONOPHOSPHATE, Ubiquitin, Ubiquitin-activating enzyme E1 1, ...
著者Yuan, L, Lv, Z, Olsen, S.K.
登録日2020-09-16
公開日2021-04-28
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (3.42 Å)
主引用文献Crystal structures of an E1-E2-ubiquitin thioester mimetic reveal molecular mechanisms of transthioesterification.
Nat Commun, 12, 2021
7KD3
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BU of 7kd3 by Molmil
Structure of an HxlR/DUF24 family transcription regulator, CdTR_3200 from hypervirulent Clostridioides difficile R20291
分子名称: Putative transcriptional regulator
著者Menon, S.K, Isom, C.E, Karr, E.A.
登録日2020-10-07
公開日2021-09-15
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structure of an HxlR/DUF24 family transcription regulator, CdTR_3200 from hypervirulent Clostridioides difficile R20291
To Be Published
7E4V
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BU of 7e4v by Molmil
Crystal structure of mosquito Staufen dsRNA binding domain 4
分子名称: GLYCEROL, Staufen
著者Gayathiri, S.K, Jobichen, C, Mok, Y.K.
登録日2021-02-15
公開日2022-02-16
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.37 Å)
主引用文献Crystal structure of mosquito Staufen dsRNA binding domain 4
To Be Published
7QOS
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BU of 7qos by Molmil
Cyclopropane fatty acid synthase from Aquifex aeolicous with bound ligands
分子名称: 2-azanylethyl-[(2~{S})-2,3-di(hexadecanoyloxy)propoxy]phosphinic acid, CARBONATE ION, Cyclopropane-fatty-acyl-phospholipid synthase, ...
著者Lukk, T, Cronan, J.E, Nair, S.K.
登録日2021-12-28
公開日2022-02-02
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structure of cyclopropane fatty acid synthase from Aquifex aeolicus
To Be Published
7QV7
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BU of 7qv7 by Molmil
Cryo-EM structure of Hydrogen-dependent CO2 reductase.
分子名称: Hydrogen dependent carbon dioxide reductase subunit FdhF, Hydrogen dependent carbon dioxide reductase subunit HycB3, Hydrogen dependent carbon dioxide reductase subunit HycB4, ...
著者Dietrich, H.M, Righetto, R.D, Kumar, A, Wietrzynski, W, Schuller, S.K, Trischler, R, Wagner, J, Schwarz, F.M, Engel, B.D, Mueller, V, Schuller, J.M.
登録日2022-01-19
公開日2022-07-06
最終更新日2022-08-10
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Membrane-anchored HDCR nanowires drive hydrogen-powered CO 2 fixation.
Nature, 607, 2022
7RRO
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BU of 7rro by Molmil
Structure of the 48-nm repeat doublet microtubule from bovine tracheal cilia
分子名称: Armadillo repeat containing 4, Chromosome 3 C1orf194 homolog, Cilia and flagella associated protein 161, ...
著者Gui, M, Anderson, J.R, Botsch, J.J, Meleppattu, S, Singh, S.K, Zhang, Q, Brown, A.
登録日2021-08-10
公開日2021-10-27
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献De novo identification of mammalian ciliary motility proteins using cryo-EM.
Cell, 184, 2021
7RC3
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BU of 7rc3 by Molmil
Aeronamide N-methyltransferase, AerE (Y137F)
分子名称: ASPARTIC ACID, CALCIUM ION, HEXAETHYLENE GLYCOL, ...
著者Cogan, D.P, Reyes, R, Nair, S.K.
登録日2021-07-07
公開日2022-03-30
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.53 Å)
主引用文献Structure and mechanism for iterative amide N -methylation in the biosynthesis of channel-forming peptide cytotoxins.
Proc.Natl.Acad.Sci.USA, 119, 2022
7RC4
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BU of 7rc4 by Molmil
Aeronamide N-methyltransferase, AerE (D141A)
分子名称: CALCIUM ION, HEXAETHYLENE GLYCOL, Methyltransferase family protein, ...
著者Cogan, D.P, Reyes, R, Nair, S.K.
登録日2021-07-07
公開日2022-03-30
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.66 Å)
主引用文献Structure and mechanism for iterative amide N -methylation in the biosynthesis of channel-forming peptide cytotoxins.
Proc.Natl.Acad.Sci.USA, 119, 2022
7RC2
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BU of 7rc2 by Molmil
Aeronamide N-methyltransferase, AerE
分子名称: CALCIUM ION, Methyltransferase family protein, S-ADENOSYL-L-HOMOCYSTEINE, ...
著者Cogan, D.P, Reyes, R, Nair, S.K.
登録日2021-07-07
公開日2022-03-30
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (1.51 Å)
主引用文献Structure and mechanism for iterative amide N -methylation in the biosynthesis of channel-forming peptide cytotoxins.
Proc.Natl.Acad.Sci.USA, 119, 2022
7RC6
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BU of 7rc6 by Molmil
Aeronamide N-methyltransferase, AerE, bound to modified peptide substrate, AerA-DL,34
分子名称: Aeronamide A peptide, Methyltransferase family protein, S-ADENOSYL-L-HOMOCYSTEINE, ...
著者Cogan, D.P, Reyes, R, Nair, S.K.
登録日2021-07-07
公開日2022-03-30
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.71 Å)
主引用文献Structure and mechanism for iterative amide N -methylation in the biosynthesis of channel-forming peptide cytotoxins.
Proc.Natl.Acad.Sci.USA, 119, 2022
7RC5
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BU of 7rc5 by Molmil
Aeronamide N-methyltransferase, AerE (N231A)
分子名称: CALCIUM ION, Methyltransferase family protein, S-ADENOSYL-L-HOMOCYSTEINE, ...
著者Cogan, D.P, Reyes, R, Nair, S.K.
登録日2021-07-07
公開日2022-03-30
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.88 Å)
主引用文献Structure and mechanism for iterative amide N -methylation in the biosynthesis of channel-forming peptide cytotoxins.
Proc.Natl.Acad.Sci.USA, 119, 2022
7RI3
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BU of 7ri3 by Molmil
Crystal structure of Albireti Toxin, a diphtheria toxin homolog, from Streptomyces albireticuli
分子名称: ACETATE ION, CALCIUM ION, Diphtheria_T domain-containing protein, ...
著者Sugiman-Marangos, S.N, Gill, S.K, Melnyk, R.A.
登録日2021-07-19
公開日2022-04-20
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.69 Å)
主引用文献Structures of distant diphtheria toxin homologs reveal functional determinants of an evolutionarily conserved toxin scaffold.
Commun Biol, 5, 2022
7RB4
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BU of 7rb4 by Molmil
Crystal structure of Peptono Toxin, a diphtheria toxin homolog, from Seinonella peptonophila
分子名称: Diphtheria toxin, C domain, IODIDE ION
著者Sugiman-Marangos, S.N, Gill, S.K, Melnyk, R.A.
登録日2021-07-05
公開日2022-04-20
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (2.19 Å)
主引用文献Structures of distant diphtheria toxin homologs reveal functional determinants of an evolutionarily conserved toxin scaffold.
Commun Biol, 5, 2022
7REN
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BU of 7ren by Molmil
Room temperature serial crystal structure of Glutaminase C in complex with inhibitor UPGL-00004
分子名称: 2-phenyl-N-{5-[4-({5-[(phenylacetyl)amino]-1,3,4-thiadiazol-2-yl}amino)piperidin-1-yl]-1,3,4-thiadiazol-2-yl}acetamide, Glutaminase kidney isoform, mitochondrial
著者Milano, S.K, Finke, A, Cerione, R.A.
登録日2021-07-13
公開日2022-05-25
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献New insights into the molecular mechanisms of glutaminase C inhibitors in cancer cells using serial room temperature crystallography.
J.Biol.Chem., 298, 2022
7RGG
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BU of 7rgg by Molmil
Room temperature serial crystal structure of Glutaminase C in complex with inhibitor BPTES
分子名称: Glutaminase kidney isoform, mitochondrial 68 kDa chain, N,N'-[sulfanediylbis(ethane-2,1-diyl-1,3,4-thiadiazole-5,2-diyl)]bis(2-phenylacetamide)
著者Milano, S.K, Finke, A, Cerione, R.A.
登録日2021-07-15
公開日2022-05-25
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献New insights into the molecular mechanisms of glutaminase C inhibitors in cancer cells using serial room temperature crystallography.
J.Biol.Chem., 298, 2022
7RTY
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BU of 7rty by Molmil
Crystal Structure of PsfC from Pseudomonas syringae PB-5123
分子名称: FE (II) ION, PsfC
著者Ongpipattanakul, C, Nair, S.K.
登録日2021-08-16
公開日2021-09-15
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (1.963 Å)
主引用文献Biosynthesis of fosfomycin in pseudomonads reveals an unexpected enzymatic activity in the metallohydrolase superfamily.
Proc.Natl.Acad.Sci.USA, 118, 2021
1OQG
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BU of 1oqg by Molmil
Crystal structure of the D63E mutant of the N-lobe human transferrin
分子名称: CARBONATE ION, FE (III) ION, Serotransferrin
著者Baker, H.M, He, Q.-Y, Brigg, S.K, Mason, A.B, Baker, E.N.
登録日2003-03-09
公開日2003-03-18
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural and functional consequences of binding site mutations in transferrin: crystal structures of the Asp63Glu and Arg124Ala mutants of the N-lobe of human transferrin
Biochemistry, 42, 2003
6T5M
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BU of 6t5m by Molmil
Crystal structure of 2-methylisocitrate lyase (PrpB) from Pseudomonas aeruginosa in complex with Mg(II)-pyruvate.
分子名称: 2-methylisocitrate lyase, MAGNESIUM ION, PYRUVIC ACID
著者Wijaya, A.J, Brear, P, Dolan, S.K, Welch, M.
登録日2019-10-16
公開日2020-09-30
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.76 Å)
主引用文献Crystal structure of 2-methylisocitrate lyase (PrpB) from Pseudomonas aeruginosa in complex with Mg(II)-pyruvate.
To Be Published
6TYI
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BU of 6tyi by Molmil
ExbB-ExbD complex in MSP1E3D1 nanodisc
分子名称: (1S)-2-{[(2-AMINOETHOXY)(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL STEARATE, (1S)-2-{[{[(2R)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL STEARATE, Biopolymer transport protein ExbB, ...
著者Celia, H, Botos, I, Jiang, J, Buchanan, S.K.
登録日2019-08-09
公開日2019-10-16
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Cryo-EM structure of the bacterial Ton motor subcomplex ExbB-ExbD provides information on structure and stoichiometry.
Commun Biol, 2, 2019
6U42
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BU of 6u42 by Molmil
Natively decorated ciliary doublet microtubule
分子名称: DC1, DC2, DC3, ...
著者Ma, M, Stoyanova, M, Rademacher, G, Dutcher, S.K, Brown, A, Zhang, R.
登録日2019-08-22
公開日2019-11-13
最終更新日2020-01-08
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Structure of the Decorated Ciliary Doublet Microtubule.
Cell, 179, 2019
6UAK
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BU of 6uak by Molmil
LahSb - C-terminal methyltransferase involved in RiPP biosynthesis
分子名称: S-ADENOSYL-L-HOMOCYSTEINE, SAM dependent methyltransferase LahSB
著者Nair, S.K, Estrada, P.
登録日2019-09-10
公開日2019-12-04
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.01 Å)
主引用文献Characterization of a Dehydratase and Methyltransferase in the Biosynthesis of Ribosomally Synthesized and Post-translationally Modified Peptides in Lachnospiraceae.
Chembiochem, 21, 2020
6UK5
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BU of 6uk5 by Molmil
Structure of SAM bound CalS10, an amino pentose methyltransferase from Micromonospora echinaspora involved in calicheamicin biosynthesis
分子名称: ACETATE ION, CalS10, DI(HYDROXYETHYL)ETHER, ...
著者Alvarado, S.K, Miller, M.D, Xu, W, Wang, Z, Van Lanen, S.G, Thorson, J.S, Phillips Jr, G.N.
登録日2019-10-04
公開日2020-10-07
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structure of SAM bound CalS10, an amino pentose methyltransferase from Micromonospora echinaspora involved in calicheamicin biosynthesis
To Be Published

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