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5ZVC
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BU of 5zvc by Molmil
P domain of GII.13 norovirus capsid complexed with Lewis A trisaccharide
分子名称: GLYCEROL, Major capsid protein VP1, beta-D-galactopyranose-(1-3)-[alpha-L-fucopyranose-(1-4)]2-acetamido-2-deoxy-beta-D-glucopyranose
著者Chen, Y, Li, X.
登録日2018-05-10
公開日2018-10-03
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural Adaptations of Norovirus GII.17/13/21 Lineage through Two Distinct Evolutionary Paths.
J. Virol., 93, 2019
5ZV9
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BU of 5zv9 by Molmil
P domain of GII.13 norovirus capsid
分子名称: GLYCEROL, Major capsid protein VP1
著者Chen, Y, Li, X.
登録日2018-05-09
公開日2018-10-03
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural Adaptations of Norovirus GII.17/13/21 Lineage through Two Distinct Evolutionary Paths.
J. Virol., 93, 2019
5ZV5
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BU of 5zv5 by Molmil
P domain of GII.17-2014/15 complexed with A-trisaccharide
分子名称: VP1, alpha-L-fucopyranose-(1-2)-[2-acetamido-2-deoxy-alpha-D-galactopyranose-(1-3)]alpha-D-galactopyranose
著者Chen, Y, Li, X.
登録日2018-05-09
公開日2018-10-03
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural Adaptations of Norovirus GII.17/13/21 Lineage through Two Distinct Evolutionary Paths.
J. Virol., 93, 2019
8Y3X
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BU of 8y3x by Molmil
Cell divisome sPG hydrolysis machinery FtsEX-EnvC
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Cell division ATP-binding protein FtsE, Cell division protein FtsX, ...
著者Zhang, Z, Dong, H, Chen, Y.
登録日2024-01-29
公開日2024-05-08
最終更新日2025-07-02
実験手法ELECTRON MICROSCOPY (3.11 Å)
主引用文献Structure and activity of the septal peptidoglycan hydrolysis machinery crucial for bacterial cell division.
Plos Biol., 22, 2024
5ZUQ
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BU of 5zuq by Molmil
P domain of GII.17-1978
分子名称: VP1
著者Chen, Y, Li, X.
登録日2018-05-08
公開日2018-10-03
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.99 Å)
主引用文献Structural Adaptations of Norovirus GII.17/13/21 Lineage through Two Distinct Evolutionary Paths.
J. Virol., 93, 2019
5ZUS
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BU of 5zus by Molmil
P domain of GII.17-2014/15
分子名称: VP1
著者Chen, Y, Li, X.
登録日2018-05-08
公開日2018-10-03
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural Adaptations of Norovirus GII.17/13/21 Lineage through Two Distinct Evolutionary Paths.
J. Virol., 93, 2019
3R24
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BU of 3r24 by Molmil
Crystal structure of nsp10/nsp16 complex of SARS coronavirus
分子名称: 2'-O-methyl transferase, Non-structural protein 10 and Non-structural protein 11, S-ADENOSYLMETHIONINE, ...
著者Liu, X, Guo, D, Su, C, Chen, Y.
登録日2011-03-13
公開日2011-10-26
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Biochemical and structural insights into the mechanisms of SARS coronavirus RNA ribose 2'-O-methylation by nsp16/nsp10 protein complex.
Plos Pathog., 7, 2011
7EJU
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BU of 7eju by Molmil
Junin virus(JUNV) RNA polymerase L complexed with Z protein
分子名称: MAGNESIUM ION, RING finger protein Z, RNA-directed RNA polymerase L, ...
著者Chen, Y.
登録日2021-04-02
公開日2021-07-07
最終更新日2025-06-18
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Structural basis for recognition and regulation of arenavirus polymerase L by Z protein.
Nat Commun, 12, 2021
7CWE
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BU of 7cwe by Molmil
Human Fructose-1,6-bisphosphatase 1 in APO R-state
分子名称: Fructose-1,6-bisphosphatase 1, MAGNESIUM ION
著者Chen, Y, Zhang, J, Li, C, Cao, Y.
登録日2020-08-28
公開日2021-09-08
最終更新日2024-11-13
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Human Fructose-1,6-bisphosphatase 1 in APO R-state
To Be Published
7V4L
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BU of 7v4l by Molmil
Cryo-EM Structure of Camellia sinensis glutamine synthetase CsGSIb inactive Pentamer State III
分子名称: Glutamine synthetase
著者Xu, W, Chen, Y, Xing, Q, Huang, C.
登録日2021-08-13
公開日2022-05-18
最終更新日2025-07-02
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Assembly status transition offers an avenue for activity modulation of a supramolecular enzyme.
Elife, 10, 2021
7V4J
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BU of 7v4j by Molmil
Cryo-EM Structure of Camellia sinensis glutamine synthetase CsGSIb inactive Pentamer State I
分子名称: Glutamine synthetase
著者Xu, W, Chen, Y, Xing, Q, Huang, C.
登録日2021-08-13
公開日2022-05-18
最終更新日2025-07-02
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Assembly status transition offers an avenue for activity modulation of a supramolecular enzyme.
Elife, 10, 2021
7V4I
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BU of 7v4i by Molmil
Cryo-EM Structure of Camellia sinensis glutamine synthetase CsGSIb decamer assembly
分子名称: Glutamine synthetase
著者Xu, W, Chen, Y, Xing, Q, Huang, C.
登録日2021-08-13
公開日2022-05-18
最終更新日2025-07-02
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Assembly status transition offers an avenue for activity modulation of a supramolecular enzyme.
Elife, 10, 2021
7V4K
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BU of 7v4k by Molmil
Cryo-EM Structure of Camellia sinensis glutamine synthetase CsGSIb inactive Pentamer State II
分子名称: Glutamine synthetase
著者Xu, W, Chen, Y, Xing, Q, Huang, C.
登録日2021-08-13
公開日2022-05-18
最終更新日2025-07-02
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Assembly status transition offers an avenue for activity modulation of a supramolecular enzyme.
Elife, 10, 2021
7V4H
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BU of 7v4h by Molmil
Cryo-EM Structure of Glycine max glutamine synthetase GmGS Beta2
分子名称: Glutamine synthetase
著者Xu, W, Chen, Y, Xing, Q, Huang, C.
登録日2021-08-13
公開日2022-05-18
最終更新日2025-07-02
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Assembly status transition offers an avenue for activity modulation of a supramolecular enzyme.
Elife, 10, 2021
9INU
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BU of 9inu by Molmil
Novel PD-L1/VISTA dual inhibitor as potential immunotherapy agents
分子名称: (2~{S})-2-[[6-methoxy-2-[(2-methyl-3-phenyl-phenyl)amino]pyrimidin-4-yl]methylamino]-3-oxidanyl-propanoic acid, Programmed cell death 1 ligand 1
著者Cheng, Y, Xiao, Y.B.
登録日2024-07-08
公開日2025-03-12
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Novel PD-L1/VISTA Dual Inhibitor as Potential Immunotherapy Agents.
J.Med.Chem., 68, 2025
8ET5
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BU of 8et5 by Molmil
Crystal structure of arabidopsis thaliana acetohydroxyacid synthase S653T mutant in complex with amidosulfuron
分子名称: 2-[3-[(4-azanyl-2-methyl-pyrimidin-5-yl)methyl]-2-[(1~{S})-1-(dioxidanyl)-1-oxidanyl-ethyl]-4-methyl-1,3-thiazol-5-yl]ethyl phosphono hydrogen phosphate, 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, Acetolactate synthase, ...
著者Guddat, L.W, Cheng, Y.
登録日2022-10-16
公開日2023-03-29
最終更新日2024-11-13
実験手法X-RAY DIFFRACTION (2.94 Å)
主引用文献Crystal Structure of the Commercial Herbicide, Amidosulfuron, in Complex with Arabidopsis thaliana Acetohydroxyacid Synthase.
J.Agric.Food Chem., 71, 2023
8ET4
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BU of 8et4 by Molmil
Crystal structure of wild-type arabidopsis thaliana acetohydroxyacid synthase in complex with amidosulfuron
分子名称: 2-[3-[(4-azanyl-2-methyl-pyrimidin-5-yl)methyl]-2-[(1~{S})-1-(dioxidanyl)-1-oxidanyl-ethyl]-4-methyl-1,3-thiazol-5-yl]ethyl phosphono hydrogen phosphate, 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, Acetolactate synthase, ...
著者Guddat, L.W, Cheng, Y.
登録日2022-10-16
公開日2023-03-29
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.95 Å)
主引用文献Crystal Structure of the Commercial Herbicide, Amidosulfuron, in Complex with Arabidopsis thaliana Acetohydroxyacid Synthase.
J.Agric.Food Chem., 71, 2023
6UTF
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BU of 6utf by Molmil
Allosteric coupling between alpha-rings of the 20S proteasome, archaea 20S proteasome singly capped with a PAN complex
分子名称: Proteasome subunit alpha, Proteasome subunit beta
著者Cheng, Y, Yu, Z.
登録日2019-10-29
公開日2020-09-09
最終更新日2025-06-04
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Allosteric coupling between alpha-rings of the 20S proteasome.
Nat Commun, 11, 2020
6UTH
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BU of 6uth by Molmil
Allosteric coupling between alpha-rings of 20S proteasome, 20S proteasome singly capped with a PA26/E102A_PANc, together with LFP incubation
分子名称: Proteasome activator protein PA26, Proteasome subunit alpha, Proteasome subunit beta
著者Cheng, Y, Yu, Z.
登録日2019-10-29
公開日2020-09-09
最終更新日2025-05-21
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Allosteric coupling between alpha-rings of the 20S proteasome.
Nat Commun, 11, 2020
6UTJ
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BU of 6utj by Molmil
Allosteric couple between alpha rings of the 20S proteasome. 20S proteasome singly capped by PA26/E102A, C-terminus replaced by PAN C-terminus
分子名称: Proteasome activator protein PA26, Proteasome subunit alpha, Proteasome subunit beta
著者Cheng, Y, Yu, Z.
登録日2019-10-29
公開日2020-09-09
最終更新日2025-05-28
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Allosteric coupling between alpha-rings of the 20S proteasome.
Nat Commun, 11, 2020
6UTI
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BU of 6uti by Molmil
Allosteric coupling between alpha-rings of 20S proteasome, 20S proteasome with singly capped PAN complex
分子名称: Proteasome subunit alpha, Proteasome subunit beta
著者Cheng, Y, Yu, Z.
登録日2019-10-29
公開日2020-09-09
最終更新日2025-05-14
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Allosteric coupling between alpha-rings of the 20S proteasome.
Nat Commun, 11, 2020
8K5N
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BU of 8k5n by Molmil
Discovery of Novel PD-L1 Inhibitors That Induce Dimerization and Degradation of PD-L1 Based on Fragment Coupling Strategy
分子名称: 3-[(1~{S})-1-[6-methoxy-3-methyl-5-[[[(2~{S})-5-oxidanylidenepyrrolidin-2-yl]methylamino]methyl]pyridin-2-yl]oxy-2,3-dihydro-1~{H}-inden-4-yl]-2-methyl-~{N}-[5-[[[(2~{S})-5-oxidanylidenepyrrolidin-2-yl]methylamino]methyl]pyridin-2-yl]benzamide, Programmed cell death 1 ligand 1
著者Cheng, Y, Xiao, Y.B.
登録日2023-07-22
公開日2024-01-03
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Discovery of Novel PD-L1 Inhibitors That Induce the Dimerization, Internalization, and Degradation of PD-L1 Based on the Fragment Coupling Strategy.
J.Med.Chem., 66, 2023
7DY7
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BU of 7dy7 by Molmil
Discovery of Novel Small-molecule Inhibitors of PD-1/PD-L1 Axis that Promotes PD-L1 Internalization and Degradation
分子名称: 2-[[3-[[5-(2-methyl-3-phenyl-phenyl)-1,3,4-oxadiazol-2-yl]amino]phenyl]methylamino]ethanol, Programmed cell death 1 ligand 1
著者Cheng, Y, Wang, T.Y, Lu, M.L, Jiang, S, Xiao, Y.B.
登録日2021-01-20
公開日2022-01-26
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.42 Å)
主引用文献Discovery of Small-Molecule Inhibitors of the PD-1/PD-L1 Axis That Promote PD-L1 Internalization and Degradation.
J.Med.Chem., 65, 2022
8JMV
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BU of 8jmv by Molmil
Flagellar fibrils from Bacillus amyloliquefaciens
分子名称: Flagella
著者Cao, Q, Cheng, Y.
登録日2023-06-05
公開日2023-12-06
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Serine peptidase Vpr forms enzymatically active fibrils outside Bacillus bacteria revealed by cryo-EM.
Nat Commun, 14, 2023
8JMW
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BU of 8jmw by Molmil
Fibril form of serine peptidase Vpr
分子名称: S8 family serine peptidase
著者Cao, Q, Cheng, Y.
登録日2023-06-05
公開日2023-12-06
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Serine peptidase Vpr forms enzymatically active fibrils outside Bacillus bacteria revealed by cryo-EM.
Nat Commun, 14, 2023

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件を2025-07-09に公開中

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