7XNQ
 
 | | SARS-CoV-2 Omicron BA.4 variant spike | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein | | 著者 | Wang, X, Wang, L. | | 登録日 | 2022-04-29 | | 公開日 | 2022-07-13 | | 最終更新日 | 2022-08-31 | | 実験手法 | ELECTRON MICROSCOPY (3.52 Å) | | 主引用文献 | BA.2.12.1, BA.4 and BA.5 escape antibodies elicited by Omicron infection.
Nature, 608, 2022
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7XIW
 | | SARS-CoV-2 Omicron BA.2 variant spike (state 1) | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein | | 著者 | Wang, X, Wang, L. | | 登録日 | 2022-04-14 | | 公開日 | 2022-07-13 | | 最終更新日 | 2022-08-31 | | 実験手法 | ELECTRON MICROSCOPY (3.62 Å) | | 主引用文献 | BA.2.12.1, BA.4 and BA.5 escape antibodies elicited by Omicron infection.
Nature, 608, 2022
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7XIZ
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7XNR
 | | SARS-CoV-2 Omicron BA.2.13 variant spike | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein | | 著者 | Wang, X, Wang, L. | | 登録日 | 2022-04-29 | | 公開日 | 2022-07-13 | | 最終更新日 | 2022-08-31 | | 実験手法 | ELECTRON MICROSCOPY (3.49 Å) | | 主引用文献 | BA.2.12.1, BA.4 and BA.5 escape antibodies elicited by Omicron infection.
Nature, 608, 2022
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7X6A
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2ICT
 | | Crystal structure of the bacterial antitoxin HigA from Escherichia coli at pH 8.5. Northeast Structural Genomics TARGET ER390. | | 分子名称: | antitoxin higa | | 著者 | Arbing, M.A, Abashidze, M, Hurley, J.M, Zhao, L, Janjua, H, Cunningham, K, Ma, L.C, Xiao, R, Liu, J, Baran, M.C, Acton, T.B, Rost, B, Inouye, M, Woychik, N.A, Montelione, G.T, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | | 登録日 | 2006-09-13 | | 公開日 | 2006-09-26 | | 最終更新日 | 2017-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.63 Å) | | 主引用文献 | Crystal Structures of Phd-Doc, HigA, and YeeU Establish Multiple Evolutionary Links between Microbial Growth-Regulating Toxin-Antitoxin Systems.
Structure, 18, 2010
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7WRO
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7WR8
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7WRL
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7WRZ
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6DMM
 | | Crystal structure of the G23A mutant of human alpha defensin HNP4. | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, Neutrophil defensin 4, SULFATE ION | | 著者 | Gohain, N, Tolbert, W.D, Pazgier, M. | | 登録日 | 2018-06-05 | | 公開日 | 2019-01-30 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.67 Å) | | 主引用文献 | Systematic mutational analysis of human neutrophil alpha-defensin HNP4.
Biochim Biophys Acta Biomembr, 1861, 2019
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6DRM
 | | OTU domain of Fam105A | | 分子名称: | Inactive ubiquitin thioesterase FAM105A | | 著者 | Ceccarelli, D.F, Sicheri, F, Cordes, S. | | 登録日 | 2018-06-12 | | 公開日 | 2019-05-08 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.06 Å) | | 主引用文献 | FAM105A/OTULINL Is a Pseudodeubiquitinase of the OTU-Class that Localizes to the ER Membrane.
Structure, 27, 2019
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8DZP
 | | momSalB bound Kappa Opioid Receptor in complex with Gi1 | | 分子名称: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ... | | 著者 | Fay, J.F, Che, T. | | 登録日 | 2022-08-08 | | 公開日 | 2023-05-03 | | 最終更新日 | 2023-05-24 | | 実験手法 | ELECTRON MICROSCOPY (2.71 Å) | | 主引用文献 | Ligand and G-protein selectivity in the kappa-opioid receptor.
Nature, 617, 2023
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8DZQ
 | | momSalB bound Kappa Opioid Receptor in complex with GoA | | 分子名称: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(o) subunit alpha, ... | | 著者 | Fay, J.F, Che, T. | | 登録日 | 2022-08-08 | | 公開日 | 2023-05-03 | | 最終更新日 | 2023-09-20 | | 実験手法 | ELECTRON MICROSCOPY (2.82 Å) | | 主引用文献 | Ligand and G-protein selectivity in the kappa-opioid receptor.
Nature, 617, 2023
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8DZS
 | | GR89,696 bound Kappa Opioid Receptor in complex with Gz | | 分子名称: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(z) subunit alpha, ... | | 著者 | Fay, J.F, Che, T. | | 登録日 | 2022-08-08 | | 公開日 | 2023-05-03 | | 最終更新日 | 2023-05-24 | | 実験手法 | ELECTRON MICROSCOPY (2.65 Å) | | 主引用文献 | Ligand and G-protein selectivity in the kappa-opioid receptor.
Nature, 617, 2023
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8DZR
 | | GR89,696 bound Kappa Opioid Receptor in complex with gustducin | | 分子名称: | G alpha gustducin protein, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | | 著者 | Fay, J.F, Che, T. | | 登録日 | 2022-08-08 | | 公開日 | 2023-05-03 | | 最終更新日 | 2023-05-31 | | 実験手法 | ELECTRON MICROSCOPY (2.61 Å) | | 主引用文献 | Ligand and G-protein selectivity in the kappa-opioid receptor.
Nature, 617, 2023
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6DMQ
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8HCZ
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8HDF
 | | Full length crystal structure of mycobacterium tuberculosis FadD23 in complex with ANP and PLM | | 分子名称: | Long-chain-fatty-acid--AMP ligase FadD23, PALMITIC ACID, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | | 著者 | Yan, M.R, Liu, X, Zhang, W, Rao, Z.H. | | 登録日 | 2022-11-04 | | 公開日 | 2023-02-15 | | 最終更新日 | 2024-05-29 | | 実験手法 | X-RAY DIFFRACTION (2.24 Å) | | 主引用文献 | The Key Roles of Mycobacterium tuberculosis FadD23 C-terminal Domain in Catalytic Mechanisms.
Front Microbiol, 14, 2023
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8HD4
 | | Full-length crystal structure of mycobacterium tuberculosis FadD23 in complex with AMPC16 | | 分子名称: | Long-chain-fatty-acid--AMP ligase FadD23, palmitoyl adenylate | | 著者 | Yan, M.R, Liu, X, Zhang, W, Rao, Z.H. | | 登録日 | 2022-11-03 | | 公開日 | 2023-02-15 | | 最終更新日 | 2024-05-29 | | 実験手法 | X-RAY DIFFRACTION (2.68 Å) | | 主引用文献 | The Key Roles of Mycobacterium tuberculosis FadD23 C-terminal Domain in Catalytic Mechanisms.
Front Microbiol, 14, 2023
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2K5E
 | | SOLUTION STRUCTURE OF PUTATIVE UNCHARACTERIZED PROTEIN GSU1278 FROM METHANOCALDOCOCCUS JANNASCHII, NORTHEAST STRUCTURAL GENOMICS CONSORTIUM (NESG) TARGET GsR195 | | 分子名称: | uncharacterized protein | | 著者 | Liu, G, Zhao, L, Ciccosanti, C, Jiang, M, Xiao, R, Swapna, G, Nair, R, Everett, J.K, Acton, T.B, Rost, B, Montelione, G.T, Northeast Structural Genomics Consortium (NESG) | | 登録日 | 2008-06-27 | | 公開日 | 2008-08-26 | | 最終更新日 | 2024-05-08 | | 実験手法 | SOLUTION NMR | | 主引用文献 | SOLUTION STRUCTURE OF PUTATIVE UNCHARACTERIZED PROTEIN GSU1278 FROM METHANOCALDOCOCCUS JANNASCHII, NORTHEAST STRUCTURAL GENOMICS CONSORTIUM (NESG) TARGET GsR195
To be Published
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2LMD
 | | Minimal Constraints Solution NMR Structure of Prospero Homeobox protein 1 from Homo sapiens, Northeast Structural Genomics Consortium Target HR4660B | | 分子名称: | Prospero homeobox protein 1 | | 著者 | Rossi, P, Lange, O.A, Lee, H, Maglaqui, M, Janjua, H, Ciccosanti, C, Zhao, L, Acton, T.B, Xiao, R, Everett, J.K, Montelione, G.T, Northeast Structural Genomics Consortium (NESG) | | 登録日 | 2011-11-29 | | 公開日 | 2011-12-21 | | 最終更新日 | 2024-05-01 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Determination of solution structures of proteins up to 40 kDa using CS-Rosetta with sparse NMR data from deuterated samples.
Proc.Natl.Acad.Sci.USA, 109, 2012
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7E14
 | | Compound2_GLP-1R_OWL833_Gs complex structure | | 分子名称: | 3-[(1S,2S)-1-(5-[(4S)-2,2-dimethyloxan-4-yl]-2-{(4S)-2-(4-fluoro-3,5-dimethylphenyl)-3-[3-(4-fluoro-1-methyl-1H-indazol-5-yl)-2-oxo-2,3-dihydro-1H-imidazol-1-yl]-4-methyl-2,4,6,7-tetrahydro-5H-pyrazolo[4,3-c]pyridine-5-carbonyl}-1H-indol-1-yl)-2-methylcyclopropyl]-1,2,4-oxadiazol-5(4H)-one, CHOLESTEROL, G protein, ... | | 著者 | Cong, Z.T, Chen, L.N, Ma, H.L, Yang, D.H, Xu, H.E, Zhang, Y, Wang, M.W. | | 登録日 | 2021-01-30 | | 公開日 | 2021-07-07 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | | 主引用文献 | Molecular insights into ago-allosteric modulation of the human glucagon-like peptide-1 receptor.
Nat Commun, 12, 2021
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2JVA
 | | NMR solution structure of peptidyl-tRNA hydrolase domain protein from Pseudomonas syringae pv. tomato. Northeast Structural Genomics Consortium target PsR211 | | 分子名称: | Peptidyl-tRNA hydrolase domain protein | | 著者 | Singarapu, K.K, Sukumaran, D, Parish, D, Eletsky, A, Zhang, Q, Zhao, L, Jiang, M, Maglaqui, M, Xiao, R, Liu, J, Baran, M.C, Swapna, G.V.T, Huang, Y.J, Acton, T.B, Rost, B, Montelione, G.T, Szyperski, T, Northeast Structural Genomics Consortium (NESG) | | 登録日 | 2007-09-14 | | 公開日 | 2007-10-02 | | 最終更新日 | 2024-05-08 | | 実験手法 | SOLUTION NMR | | 主引用文献 | NMR structure of the peptidyl-tRNA hydrolase domain from Pseudomonas syringae expands the structural coverage of the hydrolysis domains of class 1 peptide chain release factors.
Proteins, 71, 2008
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7C2E
 | | GLP-1R-Gs complex structure with a small molecule full agonist | | 分子名称: | 2-[[4-[6-[(4-cyano-2-fluoranyl-phenyl)methoxy]pyridin-2-yl]-3,6-dihydro-2~{H}-pyridin-1-yl]methyl]-3-[[(2~{S})-oxetan-2-yl]methyl]imidazo[4,5-b]pyridine-5-carboxylic acid, Glucagon-like peptide 1 receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | | 著者 | Ma, H, Yuan, D.P, Huang, W, Wenge, Z, Xu, E. | | 登録日 | 2020-05-07 | | 公開日 | 2020-08-26 | | 最終更新日 | 2020-12-16 | | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | | 主引用文献 | Structural insights into the activation of GLP-1R by a small molecule agonist.
Cell Res., 30, 2020
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