2PJC
CRYSTAL STRUCTURE OF ACTIVATED PORCINE PANCREATIC CARBOXYPEPTIDASE B ({(R)-1-[(S)-2-Benzyloxycarbonylamino-3-(4-hydroxy-phenyl)-propionylamino]-2-methyl-propyl}-hydroxy-phosphinoyloxy)-(3-guanidino-phenyl)-acetic acid COMPLEX
Summary for 2PJC
Entry DOI | 10.2210/pdb2pjc/pdb |
Related | 1Z5R 1ZG7 1ZG8 1ZG9 2PIY 2PIZ 2PJ0 2PJ1 2PJ2 2PJ3 2PJ4 2PJ5 2PJ6 2PJ7 2PJ8 2PJ9 2PJA 2PJB |
Descriptor | Carboxypeptidase B, ZINC ION, (2S)-(3-{[AMINO(IMINO)METHYL]AMINO}PHENYL){[(S)-[(1R)-1-({N-[(BENZYLOXY)CARBONYL]-L-TYROSYL}AMINO)-2-METHYLPROPYL](HYDROXY)PHOSPHORYL]OXY}ACETIC ACID, ... (4 entities in total) |
Functional Keywords | carboxypeptidase b, exopeptidase, phosphinate based inhibitor, hydrolase |
Biological source | Sus scrofa (pig) |
Cellular location | Secreted: P09955 |
Total number of polymer chains | 3 |
Total formula weight | 106340.63 |
Authors | Adler, M.,Whitlow, M. (deposition date: 2007-04-15, release date: 2008-01-22, Last modification date: 2023-08-30) |
Primary citation | Adler, M.,Buckman, B.,Bryant, J.,Chang, Z.,Chu, K.,Emayan, K.,Hrvatin, P.,Islam, I.,Morser, J.,Sukovich, D.,West, C.,Yuan, S.,Whitlow, M. Structures of potent selective peptide mimetics bound to carboxypeptidase B. Acta Crystallogr.,Sect.D, 64:149-157, 2008 Cited by PubMed: 18219114DOI: 10.1107/S0907444907057228 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.74 Å) |
Structure validation
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