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2A0S
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BU of 2a0s by Molmil
Crystal structure of 6-pyruvoyl tetrahydropterin synthase (PTPS) from Plasmodium vivax at 2.2 A resolution
分子名称: 6-pyruvoyl tetrahydropterin synthase, BIOPTERIN, ZINC ION
著者Bosch, J, Hol, W.G.J, Structural Genomics of Pathogenic Protozoa Consortium (SGPP)
登録日2005-06-16
公開日2005-07-26
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal structure of 6-pyruvoyl tetrahydropterin synthase (PTPS) from Plasmodium vivax at 2.2 A resolution
To be Published
1RL4
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BU of 1rl4 by Molmil
Plasmodium falciparum peptide deformylase complex with inhibitor
分子名称: (2R)-2-{[FORMYL(HYDROXY)AMINO]METHYL}HEXANOIC ACID, 2-{N'-[2-(5-AMINO-1-PHENYLCARBAMOYL-PENTYLCARBAMOYL)-HEXYL]-HYDRAZINOMETHYL}-HEXANOIC ACID(5-AMINO-1-PHENYLCARBAMOYL-PENTYL)-AMIDE, COBALT (II) ION, ...
著者Robien, M.A, Nguyen, K.T, Kumar, A, Hirsh, I, Turley, S, Pei, D, Hol, W.G.J.
登録日2003-11-24
公開日2003-12-09
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.18 Å)
主引用文献An improved crystal form of Plasmodium falciparum peptide deformylase.
Protein Sci., 13, 2004
1U8R
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BU of 1u8r by Molmil
Crystal Structure of an IdeR-DNA Complex Reveals a Conformational Change in Activated IdeR for Base-specific Interactions
分子名称: COBALT (II) ION, Iron-dependent repressor ideR, SODIUM ION, ...
著者Wisedchaisri, G, Holmes, R.K, Hol, W.G.J.
登録日2004-08-06
公開日2004-10-05
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Crystal Structure of an IdeR-DNA Complex Reveals a Conformational Change in Activated IdeR for Base-specific Interactions.
J.Mol.Biol., 342, 2004
1LTS
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BU of 1lts by Molmil
REFINED STRUCTURE OF E. COLI HEAT LABILE ENTEROTOXIN, A CLOSE RELATIVE OF CHOLERA TOXIN
分子名称: HEAT-LABILE ENTEROTOXIN, SUBUNIT A, SUBUNIT B
著者Sixma, T.K, Hol, W.G.J.
登録日1992-07-15
公開日1994-01-31
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Refined structure of Escherichia coli heat-labile enterotoxin, a close relative of cholera toxin.
J.Mol.Biol., 230, 1993
1NOP
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BU of 1nop by Molmil
Crystal structure of human tyrosyl-DNA phosphodiesterase (Tdp1) in complex with vanadate, DNA and a human topoisomerase I-derived peptide
分子名称: 5'-D(*AP*GP*AP*GP*TP*T)-3', VANADATE ION, topoisomerase I-derived peptide, ...
著者Davies, D.R, Interthal, H, Champoux, J.J, Hol, W.G.J.
登録日2003-01-16
公開日2003-03-11
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structure of a transition state mimic for Tdp1 assembled from vanadate, DNA, and a topoisomerase I-derived peptide
Chem.Biol., 10, 2003
1QCB
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BU of 1qcb by Molmil
ESCHERICHIA COLI HEAT LABILE ENTEROTOXIN TYPE IIB B-PENTAMER
分子名称: PROTEIN (HEAT LABILE ENTEROTOXIN TYPE IIB B-PENTAMER)
著者Merritt, E.A, Hol, W.G.J.
登録日1999-04-30
公開日2003-06-10
最終更新日2021-07-28
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal Structures of the B-Pentamer from E. coli Enterotoxin LT-IIb
To be Published
1QB5
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BU of 1qb5 by Molmil
ESCHERICHIA COLI HEAT LABILE ENTEROTOXIN TYPE IIB B-PENTAMER
分子名称: PROTEIN (HEAT LABILE ENTEROTOXIN TYPE IIB B-PENTAMER)
著者Merritt, E.A, Hol, W.G.J.
登録日1999-04-30
公開日2003-06-10
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal Structures of the B-Pentamer from E. coli Enterotoxin LT-IIb
To be Published
2W7V
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BU of 2w7v by Molmil
periplasmic domain of EpsL from Vibrio parahaemolyticus
分子名称: 1,2-ETHANEDIOL, GENERAL SECRETION PATHWAY PROTEIN L, PHOSPHATE ION
著者Abendroth, J, Kreger, A.C, Abendroth, H, Sandkvist, M, Hol, W.G.J.
登録日2009-01-06
公開日2010-03-31
最終更新日2017-06-28
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献The Dimer Formed by the Periplasmic Domain of Epsl from the Type 2 Secretion System of Vibrio Parahaemolyticus.
J.Struct.Biol., 168, 2009
1UV7
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periplasmic domain of EpsM from Vibrio cholerae
分子名称: GENERAL SECRETION PATHWAY PROTEIN M
著者Abendroth, J, Hol, W.G.J.
登録日2004-01-15
公開日2004-04-23
最終更新日2019-05-15
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献The Crystal Structure of the Periplasmic Domain of the Type II Secretion System Protein Epsm from Vibrio Cholerae: The Simplest Version of the Ferredoxin Fold
J.Mol.Biol., 338, 2004
1TC5
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BU of 1tc5 by Molmil
Structural Analysis of a probable eukaryotic D-amino acid tRNA deacylase
分子名称: Probable eukaryotic D-amino acid tRNA deacylase, LMAJ005534AAA
著者Robien, M.A, Hol, W.G.J, Structural Genomics of Pathogenic Protozoa Consortium (SGPP)
登録日2004-05-20
公開日2004-06-08
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.93 Å)
主引用文献Structural analysis of LMAJ005534AAA, a probable eukaryotic D-amino acid tRNA deacylase from Leishmania major
To be Published
1SYR
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BU of 1syr by Molmil
Initial Structural Analysis of Plasmodium falciparum thioredoxin
分子名称: thioredoxin
著者Robien, M.A, Hol, W.G.J, Structural Genomics of Pathogenic Protozoa Consortium (SGPP)
登録日2004-04-01
公開日2004-04-13
最終更新日2018-01-31
実験手法X-RAY DIFFRACTION (2.95 Å)
主引用文献Initial Structural Analysis of Plasmodium falciparum thioredoxin
To be Published
1MU7
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BU of 1mu7 by Molmil
Crystal Structure of a Human Tyrosyl-DNA Phosphodiesterase (Tdp1)-Tungstate Complex
分子名称: GLYCEROL, TUNGSTATE(VI)ION, Tyrosyl-DNA Phosphodiesterase
著者Davies, D.R, Interthal, H, Champoux, J.J, Hol, W.G.J.
登録日2002-09-23
公開日2003-01-07
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Insights Into Substrate Binding and Catalytic Mechanism of Human Tyrosyl-DNA Phosphodiesterase (Tdp1) from Vanadate- and Tungstate-Inhibited Structures
J.Mol.Biol., 324, 2003
1MU9
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BU of 1mu9 by Molmil
Crystal Structure of a Human Tyrosyl-DNA Phosphodiesterase (Tdp1)-Vanadate Complex
分子名称: GLYCEROL, Tyrosyl-DNA Phosphodiesterase, VANADATE ION
著者Davies, D.R, Interthal, H, Champoux, J.J, Hol, W.G.J.
登録日2002-09-23
公開日2003-01-07
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Insights Into Substrate Binding and Catalytic Mechanism of Human Tyrosyl-DNA Phosphodiesterase (Tdp1) from Vanadate- and Tungstate-Inhibited Structures
J.Mol.Biol., 324, 2002
1P9W
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BU of 1p9w by Molmil
Crystal Structure of Vibrio cholerae putative NTPase EpsE
分子名称: General secretion pathway protein E, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ZINC ION
著者Robien, M.A, Krumm, B.E, Sandkvist, M, Hol, W.G.J.
登録日2003-05-12
公開日2003-10-14
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Crystal structure of the extracellular protein secretion NTPase EpsE of Vibrio cholerae
J.Mol.Biol., 333, 2003
1PV2
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BU of 1pv2 by Molmil
Native Form 2 E.coli Chaperone Hsp31
分子名称: Chaperone protein hchA
著者Quigley, P.M, Korotkov, K, Baneyx, F, Hol, W.G.J.
登録日2003-06-26
公開日2004-01-13
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.71 Å)
主引用文献A new native EcHsp31 structure suggests a key role of structural flexibility for chaperone function.
Protein Sci., 13, 2004
1PZJ
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BU of 1pzj by Molmil
Cholera Toxin B-Pentamer Complexed With Nitrophenyl Galactoside 5
分子名称: Cholera Toxin B Subunit, N-{3-[4-(3-AMINO-PROPYL)-PIPERAZIN-1-YL]-PROPYL}-3-NITRO-5-(GALACTOPYRANOSYL)-ALPHA-BENZAMIDE, N-{3-[4-(3-AMINO-PROPYL)-PIPERAZIN-1-YL]-PROPYL}-3-NITRO-5-(GALACTOPYRANOSYL)-BETA-BENZAMIDE
著者Mitchell, D.D, Pickens, J.C, Korotkov, K, Fan, E, Hol, W.G.J.
登録日2003-07-11
公開日2004-03-09
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (1.46 Å)
主引用文献3,5-Substituted phenyl galactosides as leads in designing effective cholera toxin antagonists; synthesis and crystallographic studies
Bioorg.Med.Chem., 12, 2004
1N57
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Crystal Structure of Chaperone Hsp31
分子名称: Chaperone Hsp31, MAGNESIUM ION
著者Quigley, P.M, Korotkov, K, Baneyx, F, Hol, W.G.J.
登録日2002-11-04
公開日2003-03-18
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献The 1.6A Crystal Structure of the Class of Chaperone Represented by Escherichia coli Hsp31 Reveals a Putative Catalytic Triad
Proc.Natl.Acad.Sci.USA, 100, 2003
1N1E
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BU of 1n1e by Molmil
Crystal structure of Leishmania mexicana Glycerol-3-phosphate dehydrogenase complexed with DHAP and NAD
分子名称: ADENOSINE 5'-(TRIHYDROGEN DIPHOSPHATE) P'-5'-ESTER WITH 3-(AMINOCARBONYL)-4-(1-HYDROXYL-2-OXO-3-PHOSPHONOOXY-PROPYL)-1-BETA-D-RIBOFURANOSYLPYRIDINIUM INNER SALT, glycerol-3-phosphate dehydrogenase
著者Choe, J, Hol, W.G.J.
登録日2002-10-17
公開日2003-05-27
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Leishmania mexicana Glycerol-3-phosphate Dehydrogenase Showed Conformational Changes Upon Binding a Bi-substrate Adduct
J.Mol.Biol., 320, 2003
1P9R
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BU of 1p9r by Molmil
Crystal Structure of Vibrio cholerae putative NTPase EpsE
分子名称: CHLORIDE ION, General secretion pathway protein E, ZINC ION
著者Robien, M.A, Krumm, B.E, Sandkvist, M, Hol, W.G.J.
登録日2003-05-12
公開日2003-10-14
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal structure of the extracellular protein secretion NTPase EpsE of Vibrio cholerae
J.Mol.Biol., 333, 2003
1PZI
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BU of 1pzi by Molmil
Heat-Labile Enterotoxin B-Pentamer Complexed With Nitrophenyl Galactoside 2a
分子名称: Heat-labile Enterotoxin B subunit, N-(2-MORPHOLIN-4-YL-1-MORPHOLIN-4-YLMETHYL-ETHYL)-3-NITRO-5-(3,4,5-TRIHYDROXY-6-HYDROXYMETHYL-TETRAHYDRO-PYRAN-2-YLOXY)-BENZAMIDE
著者Mitchell, D.D, Pickens, J.C, Korotkov, K, Fan, E, Hol, W.G.J.
登録日2003-07-11
公開日2004-03-09
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (1.99 Å)
主引用文献3,5-Substituted phenyl galactosides as leads in designing effective cholera toxin antagonists; synthesis and crystallographic studies
Bioorg.Med.Chem., 12, 2004
1PZK
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Cholera Toxin B-Pentamer Complexed With N-Acyl Phenyl Galactoside 9h
分子名称: Cholera Toxin B Subunit, N-{3-[4-(3-AMINO-PROPYL)-PIPERAZIN-1-YL]-PROPYL}-3-(2-THIOPHEN-2-YL-ACETYLAMINO)-5-(3,4,5-TRIHYDROXY-6-HYDROXYMETHYL-TETRAHYDRO-PYRAN-2-YLOXY)-BENZAMIDE
著者Mitchell, D.D, Pickens, J.C, Korotkov, K, Fan, E, Hol, W.G.J.
登録日2003-07-11
公開日2004-03-09
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献3,5-Substituted phenyl galactosides as leads in designing effective cholera toxin antagonists; synthesis and crystallographic studies
Bioorg.Med.Chem., 12, 2004
1M66
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Crystal Structure of Leishmania mexicana GPDH Complexed with Inhibitor 2-bromo-6-chloro-purine
分子名称: 2-BROMO-6-CHLORO-PURINE, Glycerol-3-phosphate dehydrogenase, PALMITIC ACID
著者Choe, J, Suresh, S, Wisedchaisri, G, Kennedy, K.J, Gelb, M.H, Hol, W.G.J.
登録日2002-07-12
公開日2002-12-11
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Anomalous differences of light elements in determining precise binding modes of ligands to glycerol-3-phosphate dehydrogenase
Chem.Biol., 9, 2002
1M67
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Crystal Structure of Leishmania mexicana GPDH Complexed with Inhibitor 2-bromo-6-hydroxy-purine
分子名称: 2-BROMO-6-HYDROXY-PURINE, Glycerol-3-phosphate dehydrogenase, PALMITIC ACID
著者Choe, J, Suresh, S, Wisedchaisri, G, Kennedy, K.J, Gelb, M.H, Hol, W.G.J.
登録日2002-07-12
公開日2002-12-11
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Anomalous differences of light elements in determining precise binding modes of ligands to glycerol-3-phosphate dehydrogenase
Chem.Biol., 9, 2002
5V49
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Trypanosoma brucei methionyl-tRNA synthetase in complex with inhibitor (Chem 1917)
分子名称: GLYCEROL, METHIONINE, Methionyl-tRNA synthetase, ...
著者Barros-Alvarez, X, Hol, W.G.J.
登録日2017-03-08
公開日2017-07-26
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Optimization of a binding fragment targeting the "enlarged methionine pocket" leads to potent Trypanosoma brucei methionyl-tRNA synthetase inhibitors.
Bioorg. Med. Chem. Lett., 27, 2017
5USF
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Leishmania donovani tyrosyl-tRNA synthetase in complex with nanobody and inhibitor
分子名称: 5'-O-[N-(L-TYROSYL)SULFAMOYL]ADENOSINE, Immunoglobulin heavy chain variable region, Tyrosyl-tRNA synthetase, ...
著者Barros-Alvarez, X, Hol, W.G.J.
登録日2017-02-13
公開日2017-05-17
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Leishmania donovani tyrosyl-tRNA synthetase structure in complex with a tyrosyl adenylate analog and comparisons with human and protozoan counterparts.
Biochimie, 138, 2017

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