3WYI
| Structure of S. aureus undecaprenyl diphosphate synthase | 分子名称: | Isoprenyl transferase, MAGNESIUM ION | 著者 | Gao, J, Ko, T.P, Huang, C.H, Oldfield, E, Guo, R.T. | 登録日 | 2014-08-29 | 公開日 | 2015-02-04 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Antibacterial drug leads: DNA and enzyme multitargeting. J.Med.Chem., 58, 2015
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3WYJ
| Structure of E. coli undecaprenyl diphosphate synthase in complex with BPH-789 | 分子名称: | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific), [1-oxidanyl-2-[3-[3-[[3-[[3-[3-(2-oxidanyl-2,2-diphosphono-ethyl)phenyl]phenyl]sulfamoyl]phenyl]sulfonylamino]phenyl]phenyl]-1-phosphono-ethyl]phosphonic acid | 著者 | Gao, J, Ko, T.P, Huang, C.H, Oldfield, E, Guo, R.T. | 登録日 | 2014-08-29 | 公開日 | 2015-02-04 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Antibacterial drug leads: DNA and enzyme multitargeting. J.Med.Chem., 58, 2015
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3VNI
| Crystal structures of D-Psicose 3-epimerase from Clostridium cellulolyticum H10 and its complex with ketohexose sugars | 分子名称: | MANGANESE (II) ION, Xylose isomerase domain protein TIM barrel | 著者 | Chan, H.C, Zhu, Y, Hu, Y, Ko, T.P, Huang, C.H, Ren, F, Chen, C.C, Guo, R.T, Sun, Y. | 登録日 | 2012-01-16 | 公開日 | 2012-08-01 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.98 Å) | 主引用文献 | Crystal structures of D-psicose 3-epimerase from Clostridium cellulolyticum H10 and its complex with ketohexose sugars. Protein Cell, 3, 2012
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7VQ9
| Structure of MA1831 from Methanosarcina acetivorans in complex with farnesyl thiopyrophosphate and isopentyl S-thiolodiphosphate | 分子名称: | 3-methylbut-3-enylsulfanyl(phosphonooxy)phosphinic acid, Di-trans-poly-cis-decaprenylcistransferase, MAGNESIUM ION, ... | 著者 | Zhang, L.L, Chen, C.C, Liu, W.D, Huang, J.W, Zhang, X.W, Liu, B.B, Guo, R.T. | 登録日 | 2021-10-19 | 公開日 | 2022-08-31 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.89 Å) | 主引用文献 | Structural insights to a bi-functional isoprenyl diphosphate synthase that can catalyze head-to-tail and head-to-middle condensation. Int.J.Biol.Macromol., 214, 2022
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7VQD
| Structure of MA1831 from Methanosarcina acetivorans in complex with farnesyl pyrophosphate and geranylgeranyl pyrophosphate. | 分子名称: | Di-trans-poly-cis-decaprenylcistransferase, FARNESYL DIPHOSPHATE, NerylNeryl pyrophosphate, ... | 著者 | Zhang, L.L, Chen, C.C, Liu, W.D, Huang, J.W, Zhang, X.W, Liu, B.B, Guo, R.T. | 登録日 | 2021-10-19 | 公開日 | 2022-08-31 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.39 Å) | 主引用文献 | Structural insights to a bi-functional isoprenyl diphosphate synthase that can catalyze head-to-tail and head-to-middle condensation. Int.J.Biol.Macromol., 214, 2022
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7VQB
| Structure of MA1831 from Methanosarcina acetivorans in complex with farnesyl pyrophosphate and dimethylallyl diphosphate | 分子名称: | DIMETHYLALLYL DIPHOSPHATE, Di-trans-poly-cis-decaprenylcistransferase, FARNESYL DIPHOSPHATE, ... | 著者 | Zhang, L.L, Chen, C.C, Liu, W.D, Huang, J.W, Zhang, X.W, Liu, B.B, Guo, R.T. | 登録日 | 2021-10-19 | 公開日 | 2022-08-31 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.11 Å) | 主引用文献 | Structural insights to a bi-functional isoprenyl diphosphate synthase that can catalyze head-to-tail and head-to-middle condensation. Int.J.Biol.Macromol., 214, 2022
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7VQA
| Structure of MA1831 from Methanosarcina acetivorans in complex with dimethylallyl diphosphate. | 分子名称: | DIMETHYLALLYL DIPHOSPHATE, Di-trans-poly-cis-decaprenylcistransferase, MAGNESIUM ION, ... | 著者 | Zhang, L.L, Chen, C.C, Liu, W.D, Huang, J.W, Zhang, X.W, Liu, B.B, Guo, R.T. | 登録日 | 2021-10-19 | 公開日 | 2022-08-31 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.79 Å) | 主引用文献 | Structural insights to a bi-functional isoprenyl diphosphate synthase that can catalyze head-to-tail and head-to-middle condensation. Int.J.Biol.Macromol., 214, 2022
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7VQC
| Structure of MA1831 from Methanosarcina acetivorans in complex with pyrophosphate | 分子名称: | Di-trans-poly-cis-decaprenylcistransferase, PYROPHOSPHATE 2-, SULFATE ION | 著者 | Zhang, L.L, Chen, C.C, Liu, W.D, Huang, J.W, Zhang, X.W, Liu, B.B, Guo, R.T. | 登録日 | 2021-10-19 | 公開日 | 2022-08-31 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | 主引用文献 | Structural insights to a bi-functional isoprenyl diphosphate synthase that can catalyze head-to-tail and head-to-middle condensation. Int.J.Biol.Macromol., 214, 2022
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7VQ6
| Structure of a specialized glyoxalase from Gossypium hirsutum | 分子名称: | Lactoylglutathione lyase, NICKEL (II) ION | 著者 | Li, H, Hu, Y.M, Dai, L.H, Chen, C.C, Huang, J.W, Liu, W.D, Guo, R.T. | 登録日 | 2021-10-19 | 公開日 | 2022-07-27 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.39 Å) | 主引用文献 | Crystal structure and biochemical analysis of the specialized deoxynivalenol-detoxifying glyoxalase SPG from Gossypium hirsutum. Int.J.Biol.Macromol., 200, 2022
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7Y8L
| Structure of ScIRED-R2-V3 from Streptomyces clavuligerus in complex with 5-(2,5-difluorophenyl)-3,4-dihydro-2H-pyrrole | 分子名称: | 5-[2,5-bis(fluoranyl)phenyl]-3,4-dihydro-2~{H}-pyrrole, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | 著者 | Zhang, L.L, Liu, W.D, Shi, M, Huang, J.W, Yang, Y, Chen, C.C, Guo, R.T. | 登録日 | 2022-06-24 | 公開日 | 2023-06-28 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.41 Å) | 主引用文献 | Engineered Imine Reductase for Larotrectinib Intermediate Manufacture Acs Catalysis, 12, 2022
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7XWL
| structure of patulin-detoxifying enzyme Y155F/V187F with NADPH | 分子名称: | NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Short-chain dehydrogenase/reductase | 著者 | Dai, L, Li, H, Hu, Y, Guo, R.T, Chen, C.C. | 登録日 | 2022-05-26 | 公開日 | 2022-10-26 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.02 Å) | 主引用文献 | Structure-based rational design of a short-chain dehydrogenase/reductase for improving activity toward mycotoxin patulin. Int.J.Biol.Macromol., 222, 2022
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7XWK
| structure of patulin-detoxifying enzyme Y155F with NADPH and substrate | 分子名称: | (4~{S})-4-oxidanyl-4,6-dihydrofuro[3,2-c]pyran-2-one, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Short-chain dehydrogenase/reductase | 著者 | Dai, L, Li, H, Hu, Y, Guo, R.T, Chen, C.C. | 登録日 | 2022-05-26 | 公開日 | 2022-10-26 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.12 Å) | 主引用文献 | Structure-based rational design of a short-chain dehydrogenase/reductase for improving activity toward mycotoxin patulin. Int.J.Biol.Macromol., 222, 2022
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7XWH
| structure of patulin-detoxifying enzyme with NADP+ | 分子名称: | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Short-chain dehydrogenase/reductase | 著者 | Dai, L, Li, H, Hu, Y, Guo, R.T, Chen, C.C. | 登録日 | 2022-05-26 | 公開日 | 2022-10-26 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.31 Å) | 主引用文献 | Structure-based rational design of a short-chain dehydrogenase/reductase for improving activity toward mycotoxin patulin. Int.J.Biol.Macromol., 222, 2022
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7XWN
| structure of patulin-detoxifying enzyme Y155F/V187K with NADPH and substrate | 分子名称: | (4~{S})-4-oxidanyl-4,6-dihydrofuro[3,2-c]pyran-2-one, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Short-chain dehydrogenase/reductase | 著者 | Dai, L, Li, H, Hu, Y, Guo, R.T, Chen, C.C. | 登録日 | 2022-05-26 | 公開日 | 2022-10-26 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structure-based rational design of a short-chain dehydrogenase/reductase for improving activity toward mycotoxin patulin. Int.J.Biol.Macromol., 222, 2022
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7XWI
| structure of patulin-detoxifying enzyme with NADPH | 分子名称: | NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Short-chain dehydrogenase/reductase | 著者 | Dai, L, Li, H, Hu, Y, Guo, R.T, Chen, C.C. | 登録日 | 2022-05-26 | 公開日 | 2022-10-26 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.22 Å) | 主引用文献 | Structure-based rational design of a short-chain dehydrogenase/reductase for improving activity toward mycotoxin patulin. Int.J.Biol.Macromol., 222, 2022
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7XWJ
| structure of patulin-detoxifying enzyme Y155F with NADPH | 分子名称: | NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Short-chain dehydrogenase/reductase | 著者 | Dai, L, Li, H, Hu, Y, Guo, R.T, Chen, C.C. | 登録日 | 2022-05-26 | 公開日 | 2022-10-26 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.12 Å) | 主引用文献 | Structure-based rational design of a short-chain dehydrogenase/reductase for improving activity toward mycotoxin patulin. Int.J.Biol.Macromol., 222, 2022
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7Y8K
| Structure of ScIRED wild-type from Streptomyces clavuligerus | 分子名称: | Beta-hydroxyacid dehydrogenase, 3-hydroxyisobutyrate dehydrogenase | 著者 | Zhang, L.L, Liu, W.D, Shi, M, Huang, J.W, Yang, Y, Chen, C.C, Guo, R.T. | 登録日 | 2022-06-24 | 公開日 | 2023-03-22 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.08 Å) | 主引用文献 | Engineered Imine Reductase for Larotrectinib Intermediate Manufacture Acs Catalysis, 12, 2022
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7W5S
| A nonheme iron- and alpha-ketoglutarate- dependent halogenase that catalyzes nucleotide substrates | 分子名称: | CHLORIDE ION, DI(HYDROXYETHYL)ETHER, FE (II) ION, ... | 著者 | Dai, L.H, Zhang, X, Hu, Y.M, Huang, J.W, Chen, C.C, Guo, R.T. | 登録日 | 2021-11-30 | 公開日 | 2022-04-13 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (1.76 Å) | 主引用文献 | Structural and Functional Insights into a Nonheme Iron- and alpha-Ketoglutarate-Dependent Halogenase That Catalyzes Chlorination of Nucleotide Substrates. Appl.Environ.Microbiol., 88, 2022
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7W5T
| A nonheme iron- and alpha-ketoglutarate- dependent halogenase that catalyzes nucleotide substrates | 分子名称: | 2-OXOGLUTARIC ACID, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... | 著者 | Dai, L.H, Zhang, X, Hu, Y.M, Huang, J.W, Chen, C.C, Guo, R.T. | 登録日 | 2021-11-30 | 公開日 | 2022-04-13 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.74 Å) | 主引用文献 | Structural and Functional Insights into a Nonheme Iron- and alpha-Ketoglutarate-Dependent Halogenase That Catalyzes Chlorination of Nucleotide Substrates. Appl.Environ.Microbiol., 88, 2022
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7W5V
| A nonheme iron- and alpha-ketoglutarate- dependent halogenase that catalyzes nucleotide substrates | 分子名称: | CHLORIDE ION, DI(HYDROXYETHYL)ETHER, FE (III) ION, ... | 著者 | Dai, L.H, Zhang, X, Hu, Y.M, Huang, J.W, Chen, C.C, Guo, R.T. | 登録日 | 2021-11-30 | 公開日 | 2022-04-13 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.81 Å) | 主引用文献 | Structural and Functional Insights into a Nonheme Iron- and alpha-Ketoglutarate-Dependent Halogenase That Catalyzes Chlorination of Nucleotide Substrates. Appl.Environ.Microbiol., 88, 2022
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7XWM
| structure of patulin-detoxifying enzyme Y155F/V187K with NADPH | 分子名称: | NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Short-chain dehydrogenase/reductase | 著者 | Dai, L, Li, H, Hu, Y, Guo, R.T, Chen, C.C. | 登録日 | 2022-05-26 | 公開日 | 2023-04-12 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.98 Å) | 主引用文献 | Structure-based rational design of a short-chain dehydrogenase/reductase for improving activity toward mycotoxin patulin. Int.J.Biol.Macromol., 222, 2022
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7Y8N
| Structure of ScIRED-R3-V4 from Streptomyces clavuligerus in complex with 5-(2,5-difluorophenyl)-3,4-dihydro-2H-pyrrole | 分子名称: | 5-[2,5-bis(fluoranyl)phenyl]-3,4-dihydro-2~{H}-pyrrole, Beta-hydroxyacid dehydrogenase, 3-hydroxyisobutyrate dehydrogenase, ... | 著者 | Zhang, L.L, Liu, W.D, Shi, M, Huang, J.W, Yang, Y, Chen, C.C, Guo, R.T. | 登録日 | 2022-06-24 | 公開日 | 2023-05-03 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Engineered Imine Reductase for Larotrectinib Intermediate Manufacture Acs Catalysis, 12, 2022
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7WGH
| Crystal structure of AflSQS from Aspergillus flavus in complex with FSPP | 分子名称: | PHOSPHATE ION, PYROPHOSPHATE 2-, S-[(2E,6E)-3,7,11-TRIMETHYLDODECA-2,6,10-TRIENYL] TRIHYDROGEN THIODIPHOSPHATE, ... | 著者 | Shang, N, Liu, W.D, Chen, C.C, Guo, R.T. | 登録日 | 2021-12-28 | 公開日 | 2022-11-09 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.36 Å) | 主引用文献 | A Structural and Bioinformatics Investigation of a Fungal Squalene Synthase and Comparisons with Other Membrane Proteins. Acs Omega, 7, 2022
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7WGI
| Crystal structure of AflSQS from Aspergillus flavus | 分子名称: | INDOLE, PHOSPHATE ION, Squalene synthase | 著者 | Shang, N, Liu, W.D, Chen, C.C, Guo, R.T. | 登録日 | 2021-12-28 | 公開日 | 2022-11-09 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | A Structural and Bioinformatics Investigation of a Fungal Squalene Synthase and Comparisons with Other Membrane Proteins. Acs Omega, 7, 2022
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1X06
| Crystal structure of undecaprenyl pyrophosphate synthase in complex with Mg, IPP and Fspp | 分子名称: | MAGNESIUM ION, PHOSPHATE ION, S-[(2E,6E)-3,7,11-TRIMETHYLDODECA-2,6,10-TRIENYL] TRIHYDROGEN THIODIPHOSPHATE, ... | 著者 | Guo, R.-T, Ko, T.-P, Chen, A.P.-C, Kuo, C.-J, Wang, A.H.-J, Liang, P.-H. | 登録日 | 2005-03-15 | 公開日 | 2005-03-22 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Crystal structures of undecaprenyl pyrophosphate synthase in complex with magnesium, isopentenyl pyrophosphate, and farnesyl thiopyrophosphate: roles of the metal ion and conserved residues in catalysis. J.Biol.Chem., 280, 2005
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