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Structure of Csy-AcrIF24-dsDNA
分子名称:	54-MER DNA, AcrIF24, CRISPR type I-F/YPEST-associated protein Csy2, ...
著者	Zhang, L, Feng, Y.
登録日	2021-04-12
公開日	2022-04-20
最終更新日	2024-06-05
実験手法	ELECTRON MICROSCOPY (3 Å)
主引用文献	Insights into the inhibition of type I-F CRISPR-Cas system by a multifunctional anti-CRISPR protein AcrIF24. Nat Commun, 13, 2022

7XSP

Structure of gRAMP-target RNA
分子名称:	RAMP superfamily protein, RNA (35-MER), RNA (5'-R(PGPGPGPGPCPAPGPAPAPAPAPUPUPGP*G)-3'), ...
著者	Feng, Y, Zhang, L.X.
登録日	2022-05-15
公開日	2022-11-09
最終更新日	2024-07-03
実験手法	ELECTRON MICROSCOPY (2.89 Å)
主引用文献	Target RNA activates the protease activity of Craspase to confer antiviral defense. Mol.Cell, 82, 2022

7EQG

Structure of Csy-AcrIF5
分子名称:	AcrIF5, CRISPR type I-F/YPEST-associated protein Csy2, CRISPR-associated protein Csy3, ...
著者	Zhang, L, Feng, Y.
登録日	2021-05-01
公開日	2022-03-09
最終更新日	2024-06-05
実験手法	ELECTRON MICROSCOPY (3.2 Å)
主引用文献	AcrIF5 specifically targets DNA-bound CRISPR-Cas surveillance complex for inhibition. Nat.Chem.Biol., 18, 2022

6LAP

Cryo-EM structure of echovirus 11 A-particle at pH 7.4
分子名称:	Capsid protein VP1, Capsid protein VP2, Capsid protein VP3
著者	Liu, S, Gao, F.G.
登録日	2019-11-13
公開日	2020-10-07
最終更新日	2024-03-27
実験手法	ELECTRON MICROSCOPY (2.49 Å)
主引用文献	Molecular and structural basis of Echovirus 11 infection by using the dual-receptor system of CD55 and FcRn. Chin.Sci.Bull., 2020

6LNQ

The co-crystal structure of SARS-CoV 3C Like Protease with aldehyde inhibitor M7
分子名称:	N-[(2S)-3-methyl-1-[[(2S)-4-methyl-1-oxidanylidene-1-[[(2S)-1-oxidanylidene-3-[(3S)-2-oxidanylidenepyrrolidin-3-yl]propan-2-yl]amino]pentan-2-yl]amino]-1-oxidanylidene-butan-2-yl]-1H-indole-2-carboxamide, Severe Acute Respiratory Syndrome Coronavirus 3c Like Protease
著者	Wang, H, Shang, L.Q.
登録日	2020-01-01
公開日	2020-05-27
最終更新日	2024-10-23
実験手法	X-RAY DIFFRACTION (2.244 Å)
主引用文献	Comprehensive Insights into the Catalytic Mechanism of Middle East Respiratory Syndrome 3C-Like Protease and Severe Acute Respiratory Syndrome 3C-Like Protease. Acs Catalysis, 10, 2020

6LO0

The co-crystal structure of Severe Acute Respiratory Syndrome Coronavirus 3C Like Protease with aldehyde M14
分子名称:	(2~{S})-4-methyl-~{N}-[(2~{S})-1-oxidanylidene-3-[(3~{S})-2-oxidanylidenepyrrolidin-3-yl]propan-2-yl]-2-[[(~{E})-3-phenylprop-2-enoyl]amino]pentanamide, Replicase polyprotein 1a
著者	Wang, H, Shang, L.Q.
登録日	2020-01-02
公開日	2020-05-27
最終更新日	2023-11-29
実験手法	X-RAY DIFFRACTION (1.939 Å)
主引用文献	Comprehensive Insights into the Catalytic Mechanism of Middle East Respiratory Syndrome 3C-Like Protease and Severe Acute Respiratory Syndrome 3C-Like Protease. Acs Catalysis, 10, 2020

7VKA

Crystal Structure of GH3.6 in complex with an inhibitor
分子名称:	ADENOSINE MONOPHOSPHATE, GLYCEROL, Indole-3-acetic acid-amido synthetase GH3.6, ...
著者	Wang, N, Luo, M, Bao, H, Huang, H.
登録日	2021-09-29
公開日	2022-08-31
最終更新日	2023-11-29
実験手法	X-RAY DIFFRACTION (2.401 Å)
主引用文献	Chemical genetic screening identifies nalacin as an inhibitor of GH3 amido synthetase for auxin conjugation. Proc.Natl.Acad.Sci.USA, 119, 2022

3F9F

Crystal Structure of the F140A mutant of SARS-Coronovirus 3C-like Protease at pH 6.0
分子名称:	3C-like proteinase
著者	Hu, T, Li, L, Jiang, H, Shen, X.
登録日	2008-11-13
公開日	2009-09-29
最終更新日	2023-12-27
実験手法	X-RAY DIFFRACTION (2.3 Å)
主引用文献	Two adjacent mutations on the dimer interface of SARS coronavirus 3C-like protease cause different conformational changes in crystal structure. Virology, 388, 2009

6M8F

Engineered sperm whale myoglobin-based carbene transferase
分子名称:	Myoglobin, PROTOPORPHYRIN IX CONTAINING FE, SULFATE ION, ...
著者	Bacik, J.P, Ando, N, Fasan, R.
登録日	2018-08-21
公開日	2019-01-23
最終更新日	2023-10-11
実験手法	X-RAY DIFFRACTION (1.1 Å)
主引用文献	Origin of high stereocontrol in olefin cyclopropanation catalyzed by an engineered carbene transferase. Acs Catalysis, 9, 2019

6LOZ

crystal structure of alpha-momorcharin in complex with adenine
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, ADENINE, Ribosome-inactivating protein momordin I
著者	Fan, X, Jin, T.
登録日	2020-01-07
公開日	2020-11-18
最終更新日	2024-10-23
実験手法	X-RAY DIFFRACTION (1.08 Å)
主引用文献	Atomic-resolution structures of type I ribosome inactivating protein alpha-momorcharin with different substrate analogs. Int.J.Biol.Macromol., 164, 2020

6LRQ

Cryo-EM structure of A53T alpha-synuclein amyloid fibril
分子名称:	Alpha-synuclein
著者	Sun, Y.P, Zhao, K, Liu, C.
登録日	2020-01-16
公開日	2020-04-08
最終更新日	2024-03-27
実験手法	ELECTRON MICROSCOPY (3.49 Å)
主引用文献	Cryo-EM structure of full-length alpha-synuclein amyloid fibril with Parkinson's disease familial A53T mutation. Cell Res., 30, 2020

3F9H

Crystal Structure of the F140A mutant of SARS-Coronovirus 3C-like Protease at pH 7.6
分子名称:	3C-like proteinase
著者	Hu, T, Li, L, Jiang, H, Shen, X.
登録日	2008-11-13
公開日	2009-09-29
最終更新日	2023-12-27
実験手法	X-RAY DIFFRACTION (2.9 Å)
主引用文献	Two adjacent mutations on the dimer interface of SARS coronavirus 3C-like protease cause different conformational changes in crystal structure. Virology, 388, 2009

6LP0

crystal structure of alpha-momorcharin in complex with AMP
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, ADENOSINE MONOPHOSPHATE, Ribosome-inactivating protein momordin I
著者	Fan, X, Jin, T.
登録日	2020-01-07
公開日	2020-11-18
最終更新日	2023-11-29
実験手法	X-RAY DIFFRACTION (1.519 Å)
主引用文献	Atomic-resolution structures of type I ribosome inactivating protein alpha-momorcharin with different substrate analogs. Int.J.Biol.Macromol., 164, 2020

6LOR

crystal structure of alpha-momorcharin in complex with ADP
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, ADENOSINE-5'-DIPHOSPHATE, Ribosome-inactivating protein momordin I
著者	Fan, X, Jin, T.
登録日	2020-01-07
公開日	2020-11-18
最終更新日	2024-11-06
実験手法	X-RAY DIFFRACTION (1.35 Å)
主引用文献	Atomic-resolution structures of type I ribosome inactivating protein alpha-momorcharin with different substrate analogs. Int.J.Biol.Macromol., 164, 2020

6LOW

crystal structure of alpha-momorcharin in complex with GMP
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, GUANOSINE-5'-MONOPHOSPHATE, Ribosome-inactivating protein momordin I
著者	Fan, X, Jin, T.
登録日	2020-01-07
公開日	2020-11-18
最終更新日	2024-10-23
実験手法	X-RAY DIFFRACTION (1.39 Å)
主引用文献	Atomic-resolution structures of type I ribosome inactivating protein alpha-momorcharin with different substrate analogs. Int.J.Biol.Macromol., 164, 2020

7LUC

Cryo-EM structure of RSV preF bound by Fabs 32.4K and 01.4B
分子名称:	01.4B Fab Heavy chain, 01.4B Fab Light chain, 32.4K Fab Heavy chain, ...
著者	Wrapp, D, McLellan, J.S.
登録日	2021-02-22
公開日	2021-04-21
最終更新日	2021-04-28
実験手法	ELECTRON MICROSCOPY (3.21 Å)
主引用文献	Vaccination with prefusion-stabilized respiratory syncytial virus fusion protein induces genetically and antigenically diverse antibody responses. Immunity, 54, 2021

7LUE

Prefusion RSV F glycoprotein bound by neutralizing site V-directed antibody ADI-14442
分子名称:	Fusion glycoprotein F0, Heavy chain of human antibody Fab ADI-14442, Light chain of human antibody Fab ADI-14442
著者	Gilman, M.S.A, McLellan, J.S.
登録日	2021-02-22
公開日	2021-06-16
最終更新日	2024-10-30
実験手法	ELECTRON MICROSCOPY (2.9 Å)
主引用文献	Vaccination with prefusion-stabilized respiratory syncytial virus fusion protein induces genetically and antigenically diverse antibody responses. Immunity, 54, 2021

7LUD

Crystal structure of Fab ADI-14442
分子名称:	ADI-14442 Fab Heavy chain, ADI-14442 Fab Light chain, SULFATE ION
著者	Rush, S.A, McLellan, J.S.
登録日	2021-02-22
公開日	2021-06-16
最終更新日	2024-10-09
実験手法	X-RAY DIFFRACTION (2.9 Å)
主引用文献	Vaccination with prefusion-stabilized respiratory syncytial virus fusion protein induces genetically and antigenically diverse antibody responses. Immunity, 54, 2021

6INW

A Pericyclic Reaction enzyme
分子名称:	O-methyltransferase lepI, S-ADENOSYLMETHIONINE
著者	Feng, Y, Chang, M, Wang, H, Liu, Z, Zhou, Y.
登録日	2018-10-28
公開日	2019-07-03
実験手法	X-RAY DIFFRACTION (1.798 Å)
主引用文献	Crystal structure of the multifunctional SAM-dependent enzyme LepI provides insights into its catalytic mechanism. Biochem.Biophys.Res.Commun., 515, 2019

6LOQ

crystal structure of alpha-momorcharin in complex with cAMP
分子名称:	ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, Ribosome-inactivating protein momordin I
著者	Fan, X, Jin, T.
登録日	2020-01-07
公開日	2020-11-18
最終更新日	2023-11-29
実験手法	X-RAY DIFFRACTION (1.331 Å)
主引用文献	Atomic-resolution structures of type I ribosome inactivating protein alpha-momorcharin with different substrate analogs. Int.J.Biol.Macromol., 164, 2020

6LOY

crystal structure of alpha-momorcharin in complex with dAMP
分子名称:	2'-DEOXYADENOSINE-5'-MONOPHOSPHATE, Ribosome-inactivating protein momordin I
著者	Fan, X, Jin, T.
登録日	2020-01-07
公開日	2020-11-18
最終更新日	2023-11-29
実験手法	X-RAY DIFFRACTION (1.35 Å)
主引用文献	Atomic-resolution structures of type I ribosome inactivating protein alpha-momorcharin with different substrate analogs. Int.J.Biol.Macromol., 164, 2020

7LXP

Collagen Mimetic Peptide with an Xaa-position Aza-proline
分子名称:	Collagen mimetic peptide
著者	Melton, S.D, Harris, T, Chenoweth, D.M.
登録日	2021-03-04
公開日	2022-03-16
最終更新日	2023-11-15
実験手法	X-RAY DIFFRACTION (1.4 Å)
主引用文献	Collagen Mimetic Peptide with an Xaa-position Aza-proline To Be Published

3SGV

Crystal Structure of E. coli undecaprenyl pyrophosphate synthase in complex with BPH-1290
分子名称:	2-{[3-(3,4-dimethylphenoxy)phenyl]carbamoyl}-4-nitrobenzoic acid, Undecaprenyl pyrophosphate synthase
著者	Cao, R, Liu, Y.-L, Oldfield, E.
登録日	2011-06-15
公開日	2012-12-19
最終更新日	2024-02-28
実験手法	X-RAY DIFFRACTION (1.61 Å)
主引用文献	Antibacterial drug leads targeting isoprenoid biosynthesis. Proc.Natl.Acad.Sci.USA, 110, 2013

7LXQ

Collagen Mimetic Peptide with a Yaa-position Aza-proline
分子名称:	Collagen mimetic peptide
著者	Melton, S.D, Harris, T, Chenoweth, D.M.
登録日	2021-03-04
公開日	2022-03-16
最終更新日	2023-11-15
実験手法	X-RAY DIFFRACTION (1.3 Å)
主引用文献	Collagen Mimetic Peptide with a Yaa-position Aza-proline To Be Published

3S37

Structural basis for the function of two anti-VEGF receptor antibodies
分子名称:	1121B Fab heavy chain, 1121B Fab light chain, Vascular endothelial growth factor receptor 2
著者	Franklin, M.C.
登録日	2011-05-17
公開日	2011-08-24
最終更新日	2017-11-08
実験手法	X-RAY DIFFRACTION (2.7 Å)
主引用文献	The Structural Basis for the Function of Two Anti-VEGF Receptor 2 Antibodies. Structure, 19, 2011

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