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5ZUQ
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BU of 5zuq by Molmil
P domain of GII.17-1978
分子名称: VP1
著者Chen, Y, Li, X.
登録日2018-05-08
公開日2018-10-03
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.99 Å)
主引用文献Structural Adaptations of Norovirus GII.17/13/21 Lineage through Two Distinct Evolutionary Paths.
J. Virol., 93, 2019
7X4C
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BU of 7x4c by Molmil
Native CD-NTase EfCdnE
分子名称: EfCdnE, L(+)-TARTARIC ACID
著者Chen, Y, Ko, T.P, Yang, C.S, Wang, Y.C, Hou, M.H.
登録日2022-03-02
公開日2023-03-08
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Crystal structure and functional implications of cyclic di-pyrimidine-synthesizing cGAS/DncV-like nucleotidyltransferases.
Nat Commun, 14, 2023
7X4P
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BU of 7x4p by Molmil
CD-NTase EfCdnE in complex with intermediate pppUpU
分子名称: EfCdnE, MAGNESIUM ION, URIDINE 5'-TRIPHOSPHATE, ...
著者Chen, Y, Ko, T.P, Yang, C.S, Wang, Y.C, Hou, M.H.
登録日2022-03-03
公開日2023-03-08
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Crystal structure and functional implications of cyclic di-pyrimidine-synthesizing cGAS/DncV-like nucleotidyltransferases.
Nat Commun, 14, 2023
7X4A
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BU of 7x4a by Molmil
Native CD-NTase ClCdnE
分子名称: ClCdnE
著者Chen, Y, Ko, T.P, Yang, C.S, Wang, Y.C, Hou, M.H.
登録日2022-03-02
公開日2023-03-08
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.21 Å)
主引用文献Crystal structure and functional implications of cyclic di-pyrimidine-synthesizing cGAS/DncV-like nucleotidyltransferases.
Nat Commun, 14, 2023
7X4G
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BU of 7x4g by Molmil
CD-NTase ClCdnE in complex with substrate UTP
分子名称: ClCdnE, MAGNESIUM ION, URIDINE 5'-TRIPHOSPHATE
著者Chen, Y, Ko, T.P, Yang, C.S, Wang, Y.C, Hou, M.H.
登録日2022-03-02
公開日2023-03-08
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Crystal structure and functional implications of cyclic di-pyrimidine-synthesizing cGAS/DncV-like nucleotidyltransferases.
Nat Commun, 14, 2023
7X4T
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BU of 7x4t by Molmil
LpCdnE UMPNPP Mg complex
分子名称: 5'-O-[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]uridine, Cyclic dipyrimidine nucleotide synthase, GLYCEROL, ...
著者Chen, Y, Ko, T.P, Yang, C.S, Wang, Y.C, Hou, M.H.
登録日2022-03-03
公開日2023-03-08
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal structure and functional implications of cyclic di-pyrimidine-synthesizing cGAS/DncV-like nucleotidyltransferases.
Nat Commun, 14, 2023
7X4F
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BU of 7x4f by Molmil
Native CD-NTase LpCdnE
分子名称: Cyclic dipyrimidine nucleotide synthase, SULFATE ION
著者Chen, Y, Ko, T.P, Yang, C.S, Wang, Y.C, Hou, M.H.
登録日2022-03-02
公開日2023-03-08
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.46 Å)
主引用文献Crystal structure and functional implications of cyclic di-pyrimidine-synthesizing cGAS/DncV-like nucleotidyltransferases.
Nat Commun, 14, 2023
7X4Q
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BU of 7x4q by Molmil
LpCdnE UTP Mg complex
分子名称: Cyclic dipyrimidine nucleotide synthase, MAGNESIUM ION, URIDINE 5'-TRIPHOSPHATE
著者Chen, Y, Ko, T.P, Yang, C.S, Wang, Y.C, Hou, M.H.
登録日2022-03-03
公開日2023-03-08
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Crystal structure and functional implications of cyclic di-pyrimidine-synthesizing cGAS/DncV-like nucleotidyltransferases.
Nat Commun, 14, 2023
7XVN
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BU of 7xvn by Molmil
Structural basis for DNA recognition feature of retinoid-related orphan receptors
分子名称: DNA (5'-D(P*CP*AP*TP*GP*AP*CP*CP*TP*AP*CP*TP*GP*AP*CP*CP*TP*AP*G)-3'), DNA (5'-D(P*CP*TP*AP*GP*GP*TP*CP*AP*GP*TP*AP*GP*GP*TP*CP*AP*TP*G)-3'), Nuclear receptor ROR-gamma, ...
著者Chen, Y, Jiang, L.
登録日2022-05-24
公開日2023-11-29
最終更新日2024-04-17
実験手法X-RAY DIFFRACTION (2.302 Å)
主引用文献Structural characterization of the DNA binding mechanism of retinoic acid-related orphan receptor gamma.
Structure, 32, 2024
7EJU
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BU of 7eju by Molmil
Junin virus(JUNV) RNA polymerase L complexed with Z protein
分子名称: MAGNESIUM ION, RING finger protein Z, RNA-directed RNA polymerase L, ...
著者Chen, Y.
登録日2021-04-02
公開日2021-07-07
最終更新日2022-01-19
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Structural basis for recognition and regulation of arenavirus polymerase L by Z protein.
Nat Commun, 12, 2021
7CWE
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BU of 7cwe by Molmil
Human Fructose-1,6-bisphosphatase 1 in APO R-state
分子名称: Fructose-1,6-bisphosphatase 1, MAGNESIUM ION
著者Chen, Y, Zhang, J, Li, C, Cao, Y.
登録日2020-08-28
公開日2021-09-08
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Human Fructose-1,6-bisphosphatase 1 in APO R-state
To Be Published
6J0Q
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BU of 6j0q by Molmil
Crystal structure of P domain from GII.11 swine norovirus
分子名称: VP1 capsid protein
著者Chen, Y.
登録日2018-12-25
公開日2019-11-20
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural basis of host ligand specificity change of GII porcine noroviruses from their closely related GII human noroviruses.
Emerg Microbes Infect, 8, 2019
7XY7
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BU of 7xy7 by Molmil
Adenosine receptor bound to a non-selective agonist in complex with a G protein obtained by cryo-EM
分子名称: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, ...
著者Zhang, J.Y, Chen, Y, Hua, T, Song, G.J.
登録日2022-05-31
公開日2023-05-03
実験手法ELECTRON MICROSCOPY (3.26 Å)
主引用文献Cryo-EM structure of the human adenosine A 2B receptor-G s signaling complex.
Sci Adv, 8, 2022
7XY6
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BU of 7xy6 by Molmil
Adenosine receptor bound to an agonist in complex with G protein obtained by cryo-EM
分子名称: 2-[6-azanyl-3,5-dicyano-4-[4-(cyclopropylmethoxy)phenyl]pyridin-2-yl]sulfanylethanamide, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
著者Zhang, J.Y, Chen, Y, Hua, T, Song, G.J.
登録日2022-05-31
公開日2023-05-03
最終更新日2023-05-31
実験手法ELECTRON MICROSCOPY (2.99 Å)
主引用文献Cryo-EM structure of the human adenosine A 2B receptor-G s signaling complex.
Sci Adv, 8, 2022
7YA2
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BU of 7ya2 by Molmil
Crystal structure of capsular polysaccharide synthesis enzyme CapG from Staphylococcus aureus
分子名称: Capsular polysaccharide synthesis enzyme CapG
著者Chen, Y, Wang, Y.C.
登録日2022-06-27
公開日2022-11-16
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Crystal structure of the capsular polysaccharide-synthesis enzyme CapG from Staphylococcus aureus.
Acta Crystallogr.,Sect.F, 78, 2022
7YOT
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BU of 7yot by Molmil
Cryo-EM structure of RNA polymerase in complex with P protein tetramer of Newcastle disease virus
分子名称: NDV P protein, RNA-directed RNA polymerase L
著者Chen, Y, Jingyuan, C.
登録日2022-08-02
公開日2023-02-15
最終更新日2023-08-30
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Structure of the Newcastle Disease Virus L protein in complex with tetrameric phosphoprotein.
Nat Commun, 14, 2023
7YOU
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BU of 7you by Molmil
Cryo-EM structure of RNA polymerase in complex with P protein tetramer of Newcastle disease virus
分子名称: NDV P protein, RNA-directed RNA polymerase L
著者Chen, Y, Jingyuan, C, Xiaoying, F.
登録日2022-08-02
公開日2023-02-15
最終更新日2023-08-30
実験手法ELECTRON MICROSCOPY (3.41 Å)
主引用文献Structure of the Newcastle Disease Virus L protein in complex with tetrameric phosphoprotein.
Nat Commun, 14, 2023
7YOV
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BU of 7yov by Molmil
Cryo-EM structure of RNA polymerase in complex with P protein tetramer of Newcastle disease virus
分子名称: NDV P protein, RNA-directed RNA polymerase L
著者Chen, Y, Jingyuan, C, Xiaoying, F.
登録日2022-08-02
公開日2023-02-15
最終更新日2023-08-30
実験手法ELECTRON MICROSCOPY (3.25 Å)
主引用文献Structure of the Newcastle Disease Virus L protein in complex with tetrameric phosphoprotein.
Nat Commun, 14, 2023
8ET5
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BU of 8et5 by Molmil
Crystal structure of arabidopsis thaliana acetohydroxyacid synthase S653T mutant in complex with amidosulfuron
分子名称: 2-[3-[(4-azanyl-2-methyl-pyrimidin-5-yl)methyl]-2-[(1~{S})-1-(dioxidanyl)-1-oxidanyl-ethyl]-4-methyl-1,3-thiazol-5-yl]ethyl phosphono hydrogen phosphate, 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, Acetolactate synthase, ...
著者Guddat, L.W, Cheng, Y.
登録日2022-10-16
公開日2023-03-29
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.94 Å)
主引用文献Crystal Structure of the Commercial Herbicide, Amidosulfuron, in Complex with Arabidopsis thaliana Acetohydroxyacid Synthase.
J.Agric.Food Chem., 71, 2023
8ET4
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BU of 8et4 by Molmil
Crystal structure of wild-type arabidopsis thaliana acetohydroxyacid synthase in complex with amidosulfuron
分子名称: 2-[3-[(4-azanyl-2-methyl-pyrimidin-5-yl)methyl]-2-[(1~{S})-1-(dioxidanyl)-1-oxidanyl-ethyl]-4-methyl-1,3-thiazol-5-yl]ethyl phosphono hydrogen phosphate, 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, Acetolactate synthase, ...
著者Guddat, L.W, Cheng, Y.
登録日2022-10-16
公開日2023-03-29
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.95 Å)
主引用文献Crystal Structure of the Commercial Herbicide, Amidosulfuron, in Complex with Arabidopsis thaliana Acetohydroxyacid Synthase.
J.Agric.Food Chem., 71, 2023
6UTJ
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BU of 6utj by Molmil
Allosteric couple between alpha rings of the 20S proteasome. 20S proteasome singly capped by PA26/E102A, C-terminus replaced by PAN C-terminus
分子名称: Proteasome activator protein PA26, Proteasome subunit alpha, Proteasome subunit beta
著者Cheng, Y, Yu, Z.
登録日2019-10-29
公開日2020-09-09
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Allosteric coupling between alpha-rings of the 20S proteasome.
Nat Commun, 11, 2020
6UTI
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BU of 6uti by Molmil
Allosteric coupling between alpha-rings of 20S proteasome, 20S proteasome with singly capped PAN complex
分子名称: Proteasome subunit alpha, Proteasome subunit beta
著者Cheng, Y, Yu, Z.
登録日2019-10-29
公開日2020-09-09
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Allosteric coupling between alpha-rings of the 20S proteasome.
Nat Commun, 11, 2020
6UTF
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BU of 6utf by Molmil
Allosteric coupling between alpha-rings of the 20S proteasome, archaea 20S proteasome singly capped with a PAN complex
分子名称: Proteasome subunit alpha, Proteasome subunit beta
著者Cheng, Y, Yu, Z.
登録日2019-10-29
公開日2020-09-09
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Allosteric coupling between alpha-rings of the 20S proteasome.
Nat Commun, 11, 2020
6UTH
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BU of 6uth by Molmil
Allosteric coupling between alpha-rings of 20S proteasome, 20S proteasome singly capped with a PA26/E102A_PANc, together with LFP incubation
分子名称: Proteasome activator protein PA26, Proteasome subunit alpha, Proteasome subunit beta
著者Cheng, Y, Yu, Z.
登録日2019-10-29
公開日2020-09-09
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Allosteric coupling between alpha-rings of the 20S proteasome.
Nat Commun, 11, 2020
8K5N
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BU of 8k5n by Molmil
Discovery of Novel PD-L1 Inhibitors That Induce Dimerization and Degradation of PD-L1 Based on Fragment Coupling Strategy
分子名称: 3-[(1~{S})-1-[6-methoxy-3-methyl-5-[[[(2~{S})-5-oxidanylidenepyrrolidin-2-yl]methylamino]methyl]pyridin-2-yl]oxy-2,3-dihydro-1~{H}-inden-4-yl]-2-methyl-~{N}-[5-[[[(2~{S})-5-oxidanylidenepyrrolidin-2-yl]methylamino]methyl]pyridin-2-yl]benzamide, Programmed cell death 1 ligand 1
著者Cheng, Y, Xiao, Y.B.
登録日2023-07-22
公開日2024-01-03
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Discovery of Novel PD-L1 Inhibitors That Induce the Dimerization, Internalization, and Degradation of PD-L1 Based on the Fragment Coupling Strategy.
J.Med.Chem., 66, 2023

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件を2024-08-07に公開中

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