7PYV
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![BU of 7pyv by Molmil](/molmil-images/mine/7pyv) | Crystal structure of human UBA6 in complex with the ubiquitin-like modifier FAT10 | 分子名称: | UBD, Ubiquitin-like modifier-activating enzyme 6,Ubiquitin-like modifier-activating enzyme 1,Ubiquitin-like modifier-activating enzyme 6 | 著者 | Li, S, Truongvan, N, Schindelin, H. | 登録日 | 2021-10-11 | 公開日 | 2022-08-24 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (3.27 Å) | 主引用文献 | Structures of UBA6 explain its dual specificity for ubiquitin and FAT10. Nat Commun, 13, 2022
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5L6H
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5L6I
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6GF3
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![BU of 6gf3 by Molmil](/molmil-images/mine/6gf3) | Tubulin-Jerantinine B acetate complex | 分子名称: | 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, ... | 著者 | Smedley, C.J, Stanley, P.A, Qazzaz, M.E, Prota, A.E, Olieric, N, Collins, H, Eastman, H, Barrow, A.S, Lim, K.-H, Kam, T.-S, Smith, B.J, Duivenvoorden, H.M, Parker, B.S, Bradshaw, T.D, Steinmetz, M.O, Moses, J.E. | 登録日 | 2018-04-29 | 公開日 | 2019-05-08 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Sustainable Syntheses of (-)-Jerantinines A & E and Structural Characterisation of the Jerantinine-Tubulin Complex at the Colchicine Binding Site. Sci Rep, 8, 2018
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5L6J
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6ZHU
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![BU of 6zhu by Molmil](/molmil-images/mine/6zhu) | Yeast Uba1 in complex with Ubc3 and ATP | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Ubiquitin-activating enzyme E1 1, ... | 著者 | Misra, M, Schindelin, H. | 登録日 | 2020-06-23 | 公開日 | 2022-01-12 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (3.18 Å) | 主引用文献 | ATP induced conformational changes facilitate E1-E2 disulfide bridging in the ubiquitin system To Be Published
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6ZQH
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![BU of 6zqh by Molmil](/molmil-images/mine/6zqh) | Yeast Uba1 in complex with ubiquitin | 分子名称: | BETA-MERCAPTOETHANOL, GLYCEROL, TETRAETHYLENE GLYCOL, ... | 著者 | Misra, M, Schindelin, H. | 登録日 | 2020-07-09 | 公開日 | 2020-11-04 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.032 Å) | 主引用文献 | Development of ADPribosyl Ubiquitin Analogues to Study Enzymes Involved in Legionella Infection. Chemistry, 27, 2021
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8FXT
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![BU of 8fxt by Molmil](/molmil-images/mine/8fxt) | Escherichia coli periplasmic Glucose-Binding Protein glucose complex: Acrylodan conjugate attached at W183C | 分子名称: | 1-[6-(dimethylamino)naphthalen-2-yl]propan-1-one, CALCIUM ION, D-galactose/methyl-galactoside binding periplasmic protein MglB, ... | 著者 | Allert, M.J, Kumar, S, Wang, Y, Beese, L.S, Hellinga, H.W. | 登録日 | 2023-01-25 | 公開日 | 2023-08-30 | 最終更新日 | 2024-04-10 | 実験手法 | X-RAY DIFFRACTION (1.53 Å) | 主引用文献 | Chromophore carbonyl twisting in fluorescent biosensors encodes direct readout of protein conformations with multicolor switching. Commun Chem, 6, 2023
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8FXU
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![BU of 8fxu by Molmil](/molmil-images/mine/8fxu) | Thermoanaerobacter thermosaccharolyticum periplasmic Glucose-Binding Protein glucose complex: Badan conjugate attached at F17C | 分子名称: | 2-bromo-1-[6-(dimethylamino)naphthalen-2-yl]ethan-1-one, CALCIUM ION, CHLORIDE ION, ... | 著者 | Allert, M.J, Kumar, S, Beese, L.S, Hellinga, H.W. | 登録日 | 2023-01-25 | 公開日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.59 Å) | 主引用文献 | Chromophore carbonyl twisting in fluorescent biosensors encodes direct readout of protein conformations with multicolor switching. Commun Chem, 6, 2023
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6YK0
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6YJZ
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6YK1
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6GXY
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![BU of 6gxy by Molmil](/molmil-images/mine/6gxy) | Tryparedoxin from Trypanosoma brucei in complex with CFT | 分子名称: | 5-(4-fluorophenyl)-2-methyl-3~{H}-thieno[2,3-d]pyrimidin-4-one, Tryparedoxin | 著者 | Bader, N, Wagner, A, Hellmich, U, Schindelin, H. | 登録日 | 2018-06-27 | 公開日 | 2019-01-16 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Inhibitor-Induced Dimerization of an Essential Oxidoreductase from African Trypanosomes. Angew. Chem. Int. Ed. Engl., 58, 2019
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6ZHS
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![BU of 6zhs by Molmil](/molmil-images/mine/6zhs) | Uba1 bound to two E2 (Ubc13) molecules | 分子名称: | GLYCEROL, SULFATE ION, Ubiquitin-activating enzyme E1 1, ... | 著者 | Misra, M, Schindelin, H. | 登録日 | 2020-06-23 | 公開日 | 2022-01-12 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | ATP induced conformational changes facilitate E1-E2 disulfide bridging in the ubiquitin system. To Be Published
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6ZHT
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6HRS
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![BU of 6hrs by Molmil](/molmil-images/mine/6hrs) | Structure of the TRPML2 ELD at pH 4.5 | 分子名称: | GLYCEROL, Mucolipin-2 | 著者 | Bader, N, Viet, K.K, Wagner, A, Hellmich, U.A, Schindelin, H. | 登録日 | 2018-09-28 | 公開日 | 2019-06-19 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.95 Å) | 主引用文献 | Structure of the Human TRPML2 Ion Channel Extracytosolic/Lumenal Domain. Structure, 27, 2019
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6HSO
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![BU of 6hso by Molmil](/molmil-images/mine/6hso) | Crystal structure of the ternary complex of GephE-ADP-Glycine receptor derived peptide | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 1,1'-benzene-1,4-diylbis(1H-pyrrole-2,5-dione), ACETATE ION, ... | 著者 | Kasaragod, V.B, Schindelin, H. | 登録日 | 2018-10-01 | 公開日 | 2019-01-16 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Elucidating the Molecular Basis for Inhibitory Neurotransmission Regulation by Artemisinins. Neuron, 101, 2019
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6HSN
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![BU of 6hsn by Molmil](/molmil-images/mine/6hsn) | Crystal structure of the ternary complex of GephE-ADP-GABA(A) receptor derived peptide | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 1,1'-[ethane-1,2-diylbis(oxyethane-2,1-diyl)]bis(1H-pyrrole-2,5-dione), ACETATE ION, ... | 著者 | Kasaragod, V.B, Schindelin, H. | 登録日 | 2018-10-01 | 公開日 | 2019-01-16 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | Elucidating the Molecular Basis for Inhibitory Neurotransmission Regulation by Artemisinins. Neuron, 101, 2019
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6ZJC
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![BU of 6zjc by Molmil](/molmil-images/mine/6zjc) | Crystal structure of Equus ferus caballus glutathione transferase A3-3 in complex with glutathione and triethyltin | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, GLUTATHIONE, Glutathione S-transferase, ... | 著者 | Skerlova, J, Ismail, A, Lindstrom, H, Sjodin, B, Mannervik, B, Stenmark, P. | 登録日 | 2020-06-28 | 公開日 | 2020-11-18 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structural and functional analysis of the inhibition of equine glutathione transferase A3-3 by organotin endocrine disrupting pollutants. Environ Pollut, 268, 2021
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6I0Q
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6GXG
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![BU of 6gxg by Molmil](/molmil-images/mine/6gxg) | Tryparedoxin from Trypanosoma brucei in complex with CFT | 分子名称: | 5-(4-fluorophenyl)-2-methyl-3~{H}-thieno[2,3-d]pyrimidin-4-one, GLYCEROL, Tryparedoxin | 著者 | Bader, N, Wagner, A, Hellmich, U, Schindelin, H. | 登録日 | 2018-06-27 | 公開日 | 2019-01-16 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Inhibitor-Induced Dimerization of an Essential Oxidoreductase from African Trypanosomes. Angew. Chem. Int. Ed. Engl., 58, 2019
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5L6P
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![BU of 5l6p by Molmil](/molmil-images/mine/5l6p) | EphB3 kinase domain covalently bound to an irreversible inhibitor (compound 6) | 分子名称: | 1,4-DIETHYLENE DIOXIDE, Ephrin type-B receptor 3, ~{N}-(4-phenylazanylquinazolin-7-yl)ethanamide | 著者 | Schimpl, M, Overman, R, Kung, A, Chen, Y.-C, Ni, F, Zhu, J, Turner, M, Molina, H, Zhang, C. | 登録日 | 2016-05-30 | 公開日 | 2016-08-10 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.26 Å) | 主引用文献 | Development of Specific, Irreversible Inhibitors for a Receptor Tyrosine Kinase EphB3. J.Am.Chem.Soc., 138, 2016
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5L6O
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![BU of 5l6o by Molmil](/molmil-images/mine/5l6o) | EphB3 kinase domain covalently bound to an irreversible inhibitor (compound 3) | 分子名称: | 1,4-DIETHYLENE DIOXIDE, 1-(4-phenylazanylquinazolin-7-yl)ethanone, Ephrin type-B receptor 3 | 著者 | Schimpl, M, Overman, R, Kung, A, Chen, Y.-C, Ni, F, Zhu, J, Turner, M, Molina, H, Zhang, C. | 登録日 | 2016-05-30 | 公開日 | 2016-08-10 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.88 Å) | 主引用文献 | Development of Specific, Irreversible Inhibitors for a Receptor Tyrosine Kinase EphB3. J.Am.Chem.Soc., 138, 2016
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6CST
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![BU of 6cst by Molmil](/molmil-images/mine/6cst) | Structure of human DNA polymerase kappa with DNA | 分子名称: | 1,2-ETHANEDIOL, 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]adenosine, CHLORIDE ION, ... | 著者 | Jha, V, Ling, H. | 登録日 | 2018-03-21 | 公開日 | 2019-01-30 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | 2.0 angstrom resolution crystal structure of human pol kappa reveals a new catalytic function of N-clasp in DNA replication. Sci Rep, 8, 2018
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6ZJ9
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![BU of 6zj9 by Molmil](/molmil-images/mine/6zj9) | Crystal structure of Equus ferus caballus glutathione transferase A3-3 in complex with glutathione | 分子名称: | 1,2-ETHANEDIOL, GLUTATHIONE, Glutathione S-transferase | 著者 | Skerlova, J, Ismail, A, Lindstrom, H, Sjodin, B, Mannervik, B, Stenmark, P. | 登録日 | 2020-06-28 | 公開日 | 2020-11-18 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structural and functional analysis of the inhibition of equine glutathione transferase A3-3 by organotin endocrine disrupting pollutants. Environ Pollut, 268, 2021
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