5VX1
 
 | | Bak L100A | | 分子名称: | Bcl-2 homologous antagonist/killer | | 著者 | Brouwer, J.M, Colman, P.M, Czabotar, P.E. | | 登録日 | 2017-05-23 | | 公開日 | 2017-11-15 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (1.224 Å) | | 主引用文献 | Conversion of Bim-BH3 from Activator to Inhibitor of Bak through Structure-Based Design.
Mol. Cell, 68, 2017
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8H69
 | | Cryo-EM structure of influenza RNA polymerase | | 分子名称: | Polymerase acidic protein, Polymerase basic protein 2, RNA (5'-R(*UP*AP*AP*AP*CP*UP*CP*CP*UP*GP*CP*UP*UP*UP*UP*GP*CP*U)-3'), ... | | 著者 | Li, H, Wu, Y, Liang, H, Liu, Y. | | 登録日 | 2022-10-16 | | 公開日 | 2023-06-28 | | 最終更新日 | 2023-11-15 | | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | | 主引用文献 | An intermediate state allows influenza polymerase to switch smoothly between transcription and replication cycles.
Nat.Struct.Mol.Biol., 30, 2023
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7V99
 | | catalytic core of human telomerase holoenzyme | | 分子名称: | Histone H2A type 1-B/E, Histone H2B type 1-K, Primer DNA, ... | | 著者 | Wan, F, Ding, Y, Yang, L, Wu, Z, Wu, J, Lei, M. | | 登録日 | 2021-08-24 | | 公開日 | 2022-03-30 | | 最終更新日 | 2024-10-30 | | 実験手法 | ELECTRON MICROSCOPY (3.54 Å) | | 主引用文献 | Zipper head mechanism of telomere synthesis by human telomerase.
Cell Res., 31, 2021
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7V9A
 | | biogenesis module of human telomerase holoenzyme | | 分子名称: | H/ACA ribonucleoprotein complex subunit 1, H/ACA ribonucleoprotein complex subunit 2, H/ACA ribonucleoprotein complex subunit 3, ... | | 著者 | Wan, F, Ding, Y, Yang, L, Wu, Z, Wu, J, Lei, M. | | 登録日 | 2021-08-24 | | 公開日 | 2022-03-30 | | 最終更新日 | 2024-06-12 | | 実験手法 | ELECTRON MICROSCOPY (3.94 Å) | | 主引用文献 | Zipper head mechanism of telomere synthesis by human telomerase.
Cell Res., 31, 2021
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5VWY
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5VX3
 | | Bcl-xL in complex with Bim-h3Pc-RT | | 分子名称: | 1,2-ETHANEDIOL, Bcl-2-like protein 1, Bcl-2-like protein 11 | | 著者 | Cowan, A.D, Brouwer, J.M, Colman, P.M, Czabotar, P.E. | | 登録日 | 2017-05-23 | | 公開日 | 2017-11-15 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (1.945 Å) | | 主引用文献 | Conversion of Bim-BH3 from Activator to Inhibitor of Bak through Structure-Based Design.
Mol. Cell, 68, 2017
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6WBS
 | | Human CFTR first nucleotide binding domain with dF508/V510D | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Cystic fibrosis transmembrane conductance regulator, MAGNESIUM ION | | 著者 | Simon, K.S, Kothe, M, Hilbert, B, Batchelor, J.D, Hurlbut, G.D. | | 登録日 | 2020-03-27 | | 公開日 | 2021-04-07 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.857 Å) | | 主引用文献 | Determining the Molecular Mechanism of Suppressor Mutation V510D and the Contribution of Helical Unraveling to the dF508-CFTR Defect
To Be Published
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6WQF
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5WWO
 | | Crystal structure of Enp1 | | 分子名称: | Essential nuclear protein 1, Protein LTV1 | | 著者 | Ye, K, Zhang, W. | | 登録日 | 2017-01-03 | | 公開日 | 2017-06-28 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Molecular architecture of the 90S small subunit pre-ribosome
Elife, 6, 2017
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5WYJ
 | | Cryo-EM structure of the 90S small subunit pre-ribosome (Dhr1-depleted, Enp1-TAP, state 1) | | 分子名称: | 13 kDa ribonucleoprotein-associated protein, 18S ribosomal RNA, 40S ribosomal protein S1-A, ... | | 著者 | Ye, K, Zhu, X, Sun, Q. | | 登録日 | 2017-01-13 | | 公開日 | 2017-03-29 | | 最終更新日 | 2019-10-09 | | 実験手法 | ELECTRON MICROSCOPY (8.7 Å) | | 主引用文献 | Molecular architecture of the 90S small subunit pre-ribosome.
Elife, 6, 2017
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5WWN
 | | Crystal structure of Tsr1 | | 分子名称: | Ribosome biogenesis protein TSR1, SULFATE ION | | 著者 | Ye, K, Wang, B. | | 登録日 | 2017-01-03 | | 公開日 | 2017-06-28 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.805 Å) | | 主引用文献 | Molecular architecture of the 90S small subunit pre-ribosome
Elife, 6, 2017
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5WXM
 | | Crystal structure of the Imp3 and Mpp10 complex | | 分子名称: | SULFATE ION, U3 small nucleolar RNA-associated protein MPP10, U3 small nucleolar ribonucleoprotein protein IMP3 | | 著者 | Ye, K, Zheng, S. | | 登録日 | 2017-01-07 | | 公開日 | 2017-06-28 | | 実験手法 | X-RAY DIFFRACTION (2.304 Å) | | 主引用文献 | Molecular architecture of the 90S small subunit pre-ribosome
Elife, 6, 2017
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5WWM
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5WYL
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5WYK
 | | Cryo-EM structure of the 90S small subunit pre-ribosome (Mtr4-depleted, Enp1-TAP) | | 分子名称: | 13 kDa ribonucleoprotein-associated protein, 18S ribosomal RNA, 40S ribosomal protein S1-A, ... | | 著者 | Ye, K, Zhu, X, Sun, Q. | | 登録日 | 2017-01-13 | | 公開日 | 2017-03-29 | | 最終更新日 | 2017-05-17 | | 実験手法 | ELECTRON MICROSCOPY (4.5 Å) | | 主引用文献 | Molecular architecture of the 90S small subunit pre-ribosome.
Elife, 6, 2017
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5WY3
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5VWZ
 | | Bak in complex with Bim-h3Pc | | 分子名称: | 2-(2-{2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHANOL, AMMONIUM ION, Bcl-2 homologous antagonist/killer, ... | | 著者 | Brouwer, J.M, Colman, P.M, Czabotar, P.E. | | 登録日 | 2017-05-23 | | 公開日 | 2017-11-15 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (1.622 Å) | | 主引用文献 | Conversion of Bim-BH3 from Activator to Inhibitor of Bak through Structure-Based Design.
Mol. Cell, 68, 2017
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5WXL
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5VWW
 | | Bak core latch dimer in complex with Bim-RT - Tetragonal | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, BROMIDE ION, Bcl-2 homologous antagonist/killer, ... | | 著者 | Brouwer, J.M, Colman, P.M, Czabotar, P.E. | | 登録日 | 2017-05-23 | | 公開日 | 2017-11-15 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.802 Å) | | 主引用文献 | Conversion of Bim-BH3 from Activator to Inhibitor of Bak through Structure-Based Design.
Mol. Cell, 68, 2017
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5LBV
 | | Structural basis of zika and dengue virus potent antibody cross-neutralization | | 分子名称: | SODIUM ION, alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, envelope protein E | | 著者 | Barba-Spaeth, G. | | 登録日 | 2016-06-17 | | 公開日 | 2016-07-06 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Structural basis of potent Zika-dengue virus antibody cross-neutralization.
Nature, 536, 2016
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4QMF
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8S4H
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8S4K
 | | Crystal structure of Fab-2B1 in complex with rocuronium | | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Fab-2B1 VH, Fab-2B1 VL, ... | | 著者 | Saul, F.A, Haouz, A, Bruhns, P. | | 登録日 | 2024-02-21 | | 公開日 | 2024-09-18 | | 最終更新日 | 2024-10-09 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Rocuronium-specific antibodies drive perioperative anaphylaxis but can also function as reversal agents in preclinical models.
Sci Transl Med, 16, 2024
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7NRJ
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7O5T
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