1PW7
 
 | | Crystal Structure of E. coli purine nucleoside phosphorylase complexed with 9-beta-D-arabinofuranosyladenine and sulfate/phosphate | | 分子名称: | 2-(6-AMINO-PURIN-9-YL)-5-HYDROXYMETHYL-TETRAHYDRO-FURAN-3,4-DIOL, PHOSPHATE ION, Purine nucleoside phosphorylase DeoD-type | | 著者 | Bennett, E.M, Li, C, Allan, P.W, Parker, W.B, Ealick, S.E. | | 登録日 | 2003-06-30 | | 公開日 | 2003-11-25 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structural basis for substrate specificity of Escherichia coli purine nucleoside phosphorylase.
J.Biol.Chem., 278, 2003
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3QW3
 | | Structure of Leishmania donovani OMP decarboxylase | | 分子名称: | Orotidine-5-phosphate decarboxylase/orotate phosphoribosyltransferase, putative (Ompdcase-oprtase, putative), ... | | 著者 | French, J.B, Ealick, S.E. | | 登録日 | 2011-02-26 | | 公開日 | 2011-04-20 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | The Leishmania donovani UMP synthase is essential for promastigote viability and has an unusual tetrameric structure that exhibits substrate-controlled oligomerization.
J.Biol.Chem., 286, 2011
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1U1F
 | | Structure of e. coli uridine phosphorylase complexed to 5-(m-(benzyloxy)benzyl)acyclouridine (BBAU) | | 分子名称: | 1-((2-HYDROXYETHOXY)METHYL)-5-(3-(BENZYLOXY)BENZYL)PYRIMIDINE-2,4(1H,3H)-DIONE, PHOSPHATE ION, POTASSIUM ION, ... | | 著者 | Bu, W, Settembre, E.C, Ealick, S.E. | | 登録日 | 2004-07-15 | | 公開日 | 2005-07-05 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structural basis for inhibition of Escherichia coli uridine phosphorylase by 5-substituted acyclouridines.
Acta Crystallogr.,Sect.D, 61, 2005
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1PR4
 | | Escherichia coli Purine Nucleoside Phosphorylase Complexed with 9-beta-D-ribofuranosyl-6-methylthiopurine and Phosphate/Sulfate | | 分子名称: | 2-HYDROXYMETHYL-5-(6-METHYLSULFANYL-PURIN-9-YL)-TETRAHYDRO-FURAN-3,4-DIOL, PHOSPHATE ION, Purine nucleoside phosphorylase DeoD-type | | 著者 | Bennett, E.M, Li, C, Allan, P.W, Parker, W.B, Ealick, S.E. | | 登録日 | 2003-06-19 | | 公開日 | 2003-11-25 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Structural basis for substrate specificity of Escherichia coli purine nucleoside phosphorylase.
J.Biol.Chem., 278, 2003
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3QVK
 | | Allantoin racemase from Klebsiella pneumoniae | | 分子名称: | 1-(2,5-DIOXO-2,5-DIHYDRO-1H-IMIDAZOL-4-YL)UREA, Putative hydantoin racemase | | 著者 | French, J.B, Neau, D.B, Ealick, S.E. | | 登録日 | 2011-02-25 | | 公開日 | 2011-05-04 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (1.999 Å) | | 主引用文献 | Characterization of the Structure and Function of Klebsiella pneumoniae Allantoin Racemase.
J.Mol.Biol., 410, 2011
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3QW4
 | | Structure of Leishmania donovani UMP synthase | | 分子名称: | CHLORIDE ION, UMP synthase, URIDINE-5'-MONOPHOSPHATE | | 著者 | French, J.B, Ealick, S.E. | | 登録日 | 2011-02-26 | | 公開日 | 2011-04-20 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | The Leishmania donovani UMP synthase is essential for promastigote viability and has an unusual tetrameric structure that exhibits substrate-controlled oligomerization.
J.Biol.Chem., 286, 2011
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1PBN
 | | PURINE NUCLEOSIDE PHOSPHORYLASE | | 分子名称: | PURINE NUCLEOSIDE PHOSPHORYLASE | | 著者 | Mao, C, Ealick, S.E. | | 登録日 | 1995-07-10 | | 公開日 | 1995-11-14 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Calf spleen purine nucleoside phosphorylase complexed with substrates and substrate analogues.
Biochemistry, 37, 1998
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1U1G
 | | Structure of E. coli uridine phosphorylase complexed to 5-(m-(benzyloxy)benzyl)barbituric acid (BBBA) | | 分子名称: | 1-((2-HYDROXYETHOXY)METHYL)-5-(3-(BENZYLOXY)BENZYL)-6-HYDROXYPYRIMIDINE-2,4(1H,3H)-DIONE, POTASSIUM ION, Uridine phosphorylase | | 著者 | Bu, W, Settembre, E.C, Ealick, S.E. | | 登録日 | 2004-07-15 | | 公開日 | 2005-07-05 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Structural basis for inhibition of Escherichia coli uridine phosphorylase by 5-substituted acyclouridines.
Acta Crystallogr.,Sect.D, 61, 2005
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1TZ3
 | | crystal structure of aminoimidazole riboside kinase complexed with aminoimidazole riboside | | 分子名称: | 5-AMINOIMIDAZOLE RIBONUCLEOSIDE, POTASSIUM ION, putative sugar kinase | | 著者 | Zhang, Y, Dougherty, M, Downs, D.M, Ealick, S.E. | | 登録日 | 2004-07-09 | | 公開日 | 2004-10-12 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Crystal Structure of an Aminoimidazole Riboside Kinase from Salmonella enterica; Implications for the Evolution of the Ribokinase Superfamily
STRUCTURE, 12, 2004
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1P9O
 | | Crystal Structure of Phosphopantothenoylcysteine Synthetase | | 分子名称: | Phosphopantothenoylcysteine synthetase, SULFATE ION | | 著者 | Manoj, N, Strauss, E, Begley, T.P, Ealick, S.E. | | 登録日 | 2003-05-12 | | 公開日 | 2003-09-02 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structure of human phosphopantothenoylcysteine synthetase at 2.3 A resolution.
Structure, 11, 2003
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1TYY
 | | Crystal structure of aminoimidazole riboside kinase from Salmonella enterica | | 分子名称: | POTASSIUM ION, putative sugar kinase | | 著者 | Zhang, Y, Dougherty, M, Downs, D.M, Ealick, S.E. | | 登録日 | 2004-07-08 | | 公開日 | 2004-10-07 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Crystal Structure of an Aminoimidazole Riboside Kinase from Salmonella enterica; Implications for the Evolution of the Ribokinase Superfamily
STRUCTURE, 12, 2004
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1U1D
 | | Structure of e. coli uridine phosphorylase complexed to 5-(phenylthio)acyclouridine (ptau) | | 分子名称: | 1-((2-HYDROXYETHOXY)METHYL)-5-(PHENYLTHIO)PYRIMIDINE-2,4(1H,3H)-DIONE, PHOSPHATE ION, POTASSIUM ION, ... | | 著者 | Bu, W, Settembre, E.C, Ealick, S.E. | | 登録日 | 2004-07-15 | | 公開日 | 2005-07-05 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.001 Å) | | 主引用文献 | Structural basis for inhibition of Escherichia coli uridine phosphorylase by 5-substituted acyclouridines.
Acta Crystallogr.,Sect.D, 61, 2005
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1U11
 | | PurE (N5-carboxyaminoimidazole Ribonucleotide Mutase) from the acidophile Acetobacter aceti | | 分子名称: | CITRIC ACID, PurE (N5-carboxyaminoimidazole Ribonucleotide Mutase) | | 著者 | Settembre, E.C, Chittuluru, J.R, Mill, C.P, Kappock, T.J, Ealick, S.E. | | 登録日 | 2004-07-14 | | 公開日 | 2004-09-28 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | | 主引用文献 | Acidophilic adaptations in the structure of Acetobacter aceti N5-carboxyaminoimidazole ribonucleotide mutase (PurE).
Acta Crystallogr.,Sect.D, 60, 2004
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1TYG
 | | Structure of the thiazole synthase/ThiS complex | | 分子名称: | PHOSPHATE ION, Thiazole biosynthesis protein thiG, yjbS | | 著者 | Settembre, E.C, Dorrestein, P.C, Zhai, H, Chatterjee, A, McLafferty, F.W, Begley, T.P, Ealick, S.E. | | 登録日 | 2004-07-07 | | 公開日 | 2004-09-28 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (3.15 Å) | | 主引用文献 | Thiamin Biosynthesis in Bacillus subtilis: Structure of the Thiazole Synthase/Sulfur Carrier Protein Complex
Biochemistry, 43, 2004
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1TZ6
 | | Crystal structure of aminoimidazole riboside kinase from Salmonella enterica complexed with aminoimidazole riboside and ATP analog | | 分子名称: | 5-AMINOIMIDAZOLE RIBONUCLEOSIDE, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, ... | | 著者 | Zhang, Y, Dougherty, M, Downs, D.M, Ealick, S.E. | | 登録日 | 2004-07-09 | | 公開日 | 2004-10-12 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Crystal Structure of an Aminoimidazole Riboside Kinase from Salmonella enterica; Implications for the Evolution of the Ribokinase Superfamily
STRUCTURE, 12, 2004
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1U1E
 | | Structure of e. coli uridine phosphorylase complexed to 5(phenylseleno)acyclouridine (PSAU) | | 分子名称: | 1-((2-HYDROXYETHOXY)METHYL)-5-(PHENYLSELANYL)PYRIMIDINE-2,4(1H,3H)-DIONE, PHOSPHATE ION, POTASSIUM ION, ... | | 著者 | Bu, W, Settembre, E.C, Ealick, S.E. | | 登録日 | 2004-07-15 | | 公開日 | 2005-07-05 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.001 Å) | | 主引用文献 | Structural basis for inhibition of Escherichia coli uridine phosphorylase by 5-substituted acyclouridines.
Acta Crystallogr.,Sect.D, 61, 2005
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1U1C
 | | Structure of E. coli uridine phosphorylase complexed to 5-benzylacyclouridine (BAU) | | 分子名称: | 1-((2-HYDROXYETHOXY)METHYL)-5-BENZYLPYRIMIDINE-2,4(1H,3H)-DIONE, PHOSPHATE ION, POTASSIUM ION, ... | | 著者 | Bu, W, Settembre, E.C, Ealick, S.E. | | 登録日 | 2004-07-15 | | 公開日 | 2005-07-05 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Structural basis for inhibition of Escherichia coli uridine phosphorylase by 5-substituted acyclouridines.
Acta Crystallogr.,Sect.D, 61, 2005
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1TPT
 | | THREE-DIMENSIONAL STRUCTURE OF THYMIDINE PHOSPHORYLASE FROM ESCHERICHIA COLI AT 2.8 ANGSTROMS RESOLUTION | | 分子名称: | SULFATE ION, THYMIDINE PHOSPHORYLASE, THYMINE | | 著者 | Walter, M.R, Cook, W.J, Cole, L.B, Short, S.A, Koszalka, G.W, Krenitsky, T.A, Ealick, S.E. | | 登録日 | 1990-06-14 | | 公開日 | 1991-07-15 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Three-dimensional structure of thymidine phosphorylase from Escherichia coli at 2.8 A resolution.
J.Biol.Chem., 265, 1990
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3RM5
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3RW9
 | | Crystal Structure of human Spermidine Synthase in Complex with decarboxylated S-adenosylhomocysteine | | 分子名称: | 5'-S-(3-aminopropyl)-5'-thioadenosine, Spermidine synthase | | 著者 | Seckute, J, McCloskey, D.E, Thomas, H.J, Secrist III, J.A, Pegg, A.E, Ealick, S.E. | | 登録日 | 2011-05-08 | | 公開日 | 2011-09-21 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Binding and inhibition of human spermidine synthase by decarboxylated S-adenosylhomocysteine.
Protein Sci., 20, 2011
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1OTP
 | | STRUCTURAL AND THEORETICAL STUDIES SUGGEST DOMAIN MOVEMENT PRODUCES AN ACTIVE CONFORMATION OF THYMIDINE PHOSPHORYLASE | | 分子名称: | THYMIDINE PHOSPHORYLASE | | 著者 | Pugmire, M.J, Cook, W.J, Jasanoff, A, Walter, M.R, Ealick, S.E. | | 登録日 | 1997-11-09 | | 公開日 | 1998-12-09 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Structural and theoretical studies suggest domain movement produces an active conformation of thymidine phosphorylase.
J.Mol.Biol., 281, 1998
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1PR5
 | | Escherichia coli Purine Nucleoside Phosphorylase Complexed with 7-deazaadenosine and Phosphate/Sulfate | | 分子名称: | '2-(4-AMINO-PYRROLO[2,3-D]PYRIMIDIN-7-YL)-5-HYDROXYMETHYL-TETRAHYDRO-FURAN-3,4-DIOL, PHOSPHATE ION, Purine nucleoside phosphorylase DeoD-type | | 著者 | Bennett, E.M, Li, C, Allan, P.W, Parker, W.B, Ealick, S.E. | | 登録日 | 2003-06-19 | | 公開日 | 2003-11-25 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structural basis for substrate specificity of Escherichia coli purine nucleoside phosphorylase.
J.Biol.Chem., 278, 2003
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1PR0
 | | Escherichia coli Purine Nucleoside Phosphorylase Complexed with Inosine and Phosphate/Sulfate | | 分子名称: | INOSINE, PHOSPHATE ION, Purine nucleoside phosphorylase DeoD-type | | 著者 | Bennett, E.M, Li, C, Allan, P.W, Parker, W.B, Ealick, S.E. | | 登録日 | 2003-06-19 | | 公開日 | 2003-11-25 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Structural basis for substrate specificity of Escherichia coli purine nucleoside phosphorylase.
J.Biol.Chem., 278, 2003
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3QPB
 | | Crystal Structure of Streptococcus Pyogenes Uridine Phosphorylase Reveals a Subclass of the NP-I Superfamily | | 分子名称: | 1-O-phosphono-alpha-D-ribofuranose, URACIL, Uridine phosphorylase | | 著者 | Tran, T.H, Christoffersen, S, Parker, W.B, Piskur, J, Serra, I, Terreni, M, Ealick, S.E. | | 登録日 | 2011-02-11 | | 公開日 | 2011-08-24 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (1.82 Å) | | 主引用文献 | The Crystal Structure of Streptococcus pyogenes Uridine Phosphorylase Reveals a Distinct Subfamily of Nucleoside Phosphorylases.
Biochemistry, 50, 2011
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3QVJ
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