2IVT
 
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3JXB
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1D87
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3JXC
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5VY2
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2RDE
 | | Crystal structure of VCA0042 complexed with c-di-GMP | | 分子名称: | 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), Uncharacterized protein VCA0042 | | 著者 | Benach, J, Swaminathan, S.S, Tamayo, R, Seetharaman, J, Handelman, S, Forouhar, F, Neely, H, Camilli, A, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | | 登録日 | 2007-09-22 | | 公開日 | 2007-10-30 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.92 Å) | | 主引用文献 | The structural basis of cyclic diguanylate signal transduction by PilZ domains.
Embo J., 26, 2007
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7YMN
 | | Cryo-EM structure of in vitro PHF fibril | | 分子名称: | Isoform Tau-D of Microtubule-associated protein tau | | 著者 | Li, X, Liu, C. | | 登録日 | 2022-07-28 | | 公開日 | 2022-12-14 | | 最終更新日 | 2024-07-03 | | 実験手法 | ELECTRON MICROSCOPY (3.46 Å) | | 主引用文献 | Subtle change of fibrillation condition leads to substantial alteration of recombinant Tau fibril structure.
Iscience, 25, 2022
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3JXD
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5IKJ
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2MD6
 | | NMR SOLUTION STRUCTURE OF ALPHA CONOTOXIN LO1A FROM Conus longurionis | | 分子名称: | ALPHA CONOTOXIN LO1A | | 著者 | Maiti, M, Lescrinier, E, Herdewijn, P, Lebbe, E.K.M, Peigneur, S, D'Souza, L, Tytgat, J. | | 登録日 | 2013-09-01 | | 公開日 | 2014-03-05 | | 最終更新日 | 2023-06-14 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structure-Function Elucidation of a New alpha-Conotoxin, Lo1a, from Conus longurionis.
J.Biol.Chem., 289, 2014
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5VDR
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5VDP
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5VDO
 | | Human cyclic GMP-AMP synthase (cGAS) in complex with 2',2'-cGAMP | | 分子名称: | 2-amino-9-[(1R,3R,6R,8R,9R,11S,14R,16R,17R,18R)-16-(6-amino-9H-purin-9-yl)-3,11,17,18-tetrahydroxy-3,11-dioxido-2,4,7,10,12,15-hexaoxa-3,11-diphosphatricyclo[12.2.1.1~6,9~]octadec-8-yl]-1,9-dihydro-6H-purin-6-one, Cyclic GMP-AMP synthase, ZINC ION | | 著者 | Byrnes, L.J, Hall, J.D. | | 登録日 | 2017-04-03 | | 公開日 | 2017-09-27 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (3.218 Å) | | 主引用文献 | The catalytic mechanism of cyclic GMP-AMP synthase (cGAS) and implications for innate immunity and inhibition.
Protein Sci., 26, 2017
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3G7L
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7NQD
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7NQF
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7NQE
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5VDS
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5K5E
 | | Discovery and Structure-Activity Relationships of a Highly Selective Butyrylcholinesterase Inhibitor by Structure-Based Virtual Screening | | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | De la Mora, E, Dighe, S.N, Deora, G.S, Ross, B.P, Nachon, F, Brazzolotto, X. | | 登録日 | 2016-05-23 | | 公開日 | 2016-07-27 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Discovery and Structure-Activity Relationships of a Highly Selective Butyrylcholinesterase Inhibitor by Structure-Based Virtual Screening.
J.Med.Chem., 59, 2016
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3KLO
 | | Vibrio cholerae VpsT bound to c-di-GMP | | 分子名称: | 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), D(-)-TARTARIC ACID, Transcriptional regulator VpsT | | 著者 | Krasteva, P.V, Navarro, V.A.S, Sondermann, H. | | 登録日 | 2009-11-08 | | 公開日 | 2010-02-09 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.802 Å) | | 主引用文献 | Vibrio cholerae VpsT Regulates Matrix Production and Motility by Directly Sensing Cyclic di-GMP.
Science, 327, 2010
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7K4M
 | | Crystal structure of MetAP2 Modified Hemoglobin S | | 分子名称: | CARBON MONOXIDE, Hemoglobin subunit alpha, Hemoglobin subunit beta, ... | | 著者 | Musayev, F.N, Safo, M.K, Light, D.R. | | 登録日 | 2020-09-15 | | 公開日 | 2021-10-13 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | MetAP2 inhibition modifies hemoglobin S to delay polymerization and improves blood flow in sickle cell disease.
Blood Adv, 5, 2021
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5Y63
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3KLN
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5WJI
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1OFX
 | | CRYSTAL STRUCTURE OF AN OKAZAKI FRAGMENT AT 2 ANGSTROMS RESOLUTION | | 分子名称: | DNA (5'-D(*GP*GP*GP*TP*AP*TP*AP*CP*GP*C)-3'), DNA/RNA (5'-R(*GP*CP*GP*)-D(*TP*AP*TP*AP*CP*CP*C)-3'), SPERMINE | | 著者 | Egli, M, Usman, N, Zhang, S, Rich, A. | | 登録日 | 1991-10-17 | | 公開日 | 1993-04-15 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Crystal structure of an Okazaki fragment at 2-A resolution.
Proc.Natl.Acad.Sci.USA, 89, 1992
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