7YW4
 
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7YW2
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1NYJ
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7XXB
 | | IAA bound state of AtPIN3 | | 分子名称: | 1H-INDOL-3-YLACETIC ACID, Auxin efflux carrier component 3 | | 著者 | Su, N. | | 登録日 | 2022-05-29 | | 公開日 | 2022-08-10 | | 最終更新日 | 2024-07-03 | | 実験手法 | ELECTRON MICROSCOPY (2.93 Å) | | 主引用文献 | Structures and mechanisms of the Arabidopsis auxin transporter PIN3.
Nature, 609, 2022
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4J2B
 | | RB69 DNA Polymerase L415G Ternary Complex | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(*GP*CP*GP*GP*AP*CP*TP*GP*CP*TP*TP*AP*T)-3'), ... | | 著者 | Xia, S, Wang, J, Konigsberg, W.H. | | 登録日 | 2013-02-04 | | 公開日 | 2014-02-19 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.04 Å) | | 主引用文献 | Alteration in the cavity size adjacent to the active site of RB69 DNA polymerase changes its conformational dynamics.
Nucleic Acids Res., 41, 2013
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4J2E
 | | RB69 DNA Polymerase L415M Ternary Complex | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(*GP*CP*GP*GP*AP*CP*TP*GP*CP*TP*TP*AP*G)-3'), ... | | 著者 | Xia, S, Wang, J, Konigsberg, W.H. | | 登録日 | 2013-02-04 | | 公開日 | 2014-02-19 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.02 Å) | | 主引用文献 | Alteration in the cavity size adjacent to the active site of RB69 DNA polymerase changes its conformational dynamics.
Nucleic Acids Res., 41, 2013
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4J2A
 | | RB69 DNA Polymerase L415A Ternary Complex | | 分子名称: | CALCIUM ION, DNA (5'-D(*GP*CP*GP*GP*AP*CP*TP*GP*CP*TP*TP*AP*C)-3'), DNA (5'-D(*TP*CP*GP*AP*GP*TP*AP*AP*GP*CP*AP*GP*TP*CP*CP*GP*CP*G)-3'), ... | | 著者 | Xia, S, Wang, J, Konigsberg, W.H. | | 登録日 | 2013-02-04 | | 公開日 | 2014-02-19 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Alteration in the cavity size adjacent to the active site of RB69 DNA polymerase changes its conformational dynamics.
Nucleic Acids Res., 41, 2013
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1GR5
 | | Solution Structure of apo GroEL by Cryo-Electron microscopy | | 分子名称: | 60 KDA CHAPERONIN | | 著者 | Ranson, N.A, Farr, G.W, Roseman, A.M, Gowen, B, Fenton, W.A, Horwich, A.L, Saibil, H.R. | | 登録日 | 2001-12-14 | | 公開日 | 2002-01-28 | | 最終更新日 | 2024-05-08 | | 実験手法 | ELECTRON MICROSCOPY (7.9 Å) | | 主引用文献 | ATP-Bound States of Groel Captured by Cryo-Electron Microscopy.
Cell(Cambridge,Mass.), 107, 2001
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7YEU
 | | Superfolder green fluorescent protein with phosphine unnatural amino acid P3BF | | 分子名称: | Superfolder green fluorescent protein | | 著者 | Hu, C, Duan, H.Z, Liu, X.H, Chen, Y.X, Wang, J.Y. | | 登録日 | 2022-07-06 | | 公開日 | 2023-07-26 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Genetically Encoded Phosphine Ligand for Metalloprotein Design.
J.Am.Chem.Soc., 144, 2022
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2JYJ
 | | Re-refining the tetraloop-receptor RNA-RNA complex using NMR-derived restraints and Xplor-nih (2.18) | | 分子名称: | RNA (43-MER) | | 著者 | Zuo, X, Wang, J, Foster, T.R, Schwieters, C.D, Tiede, D.M, Butcher, S.E, Wang, Y. | | 登録日 | 2007-12-13 | | 公開日 | 2008-10-07 | | 最終更新日 | 2024-05-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | RNA helical packing in solution: NMR structure of a 30 kDa GAAA tetraloop-receptor complex.
J.Mol.Biol., 351, 2005
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3VBG
 | | Structure of hDM2 with Dimer Inducing Indolyl Hydantoin RO-2443 | | 分子名称: | (5Z)-5-[(6-chloro-7-methyl-1H-indol-3-yl)methylidene]-3-(3,4-difluorobenzyl)imidazolidine-2,4-dione, E3 ubiquitin-protein ligase Mdm2 | | 著者 | Lukacs, C.M, Janson, C.A, Graves, B.J. | | 登録日 | 2012-01-02 | | 公開日 | 2012-06-27 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Activation of the p53 pathway by small-molecule-induced MDM2 and MDMX dimerization.
Proc.Natl.Acad.Sci.USA, 109, 2012
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1FWW
 | | AQUIFEX AEOLICUS KDO8P SYNTHASE IN COMPLEX WITH PEP, A5P AND CADMIUM | | 分子名称: | 2-DEHYDRO-3-DEOXYPHOSPHOOCTONATE ALDOLASE, ARABINOSE-5-PHOSPHATE, CADMIUM ION, ... | | 著者 | Duewel, H.S, Radaev, S, Wang, J, Woodard, R.W, Gatti, D.L. | | 登録日 | 2000-09-24 | | 公開日 | 2001-04-21 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Electronic structure of the metal center in the Cd(2+), Zn(2+), and Cu(2+) substituted forms of KDO8P synthase: implications for catalysis.
Biochemistry, 48, 2009
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3U15
 | | Structure of hDMX with Dimer Inducing Indolyl Hydantoin RO-2443 | | 分子名称: | (5Z)-5-[(6-chloro-7-methyl-1H-indol-3-yl)methylidene]-3-(3,4-difluorobenzyl)imidazolidine-2,4-dione, Protein Mdm4, SULFATE ION | | 著者 | Lukacs, C.M, Janson, C.A, Graves, B.J. | | 登録日 | 2011-09-29 | | 公開日 | 2012-06-27 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Activation of the p53 pathway by small-molecule-induced MDM2 and MDMX dimerization.
Proc.Natl.Acad.Sci.USA, 109, 2012
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1FWS
 | | AQUIFEX AEOLICUS KDO8P SYNTHASE IN COMPLEX WITH PEP AND CADMIUM | | 分子名称: | 2-DEHYDRO-3-DEOXYPHOSPHOOCTONATE ALDOLASE, CADMIUM ION, PHOSPHATE ION, ... | | 著者 | Duewel, H.S, Radaev, S, Wang, J, Woodard, R.W, Gatti, D.L. | | 登録日 | 2000-09-24 | | 公開日 | 2001-04-21 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Electronic structure of the metal center in the Cd(2+), Zn(2+), and Cu(2+) substituted forms of KDO8P synthase: implications for catalysis.
Biochemistry, 48, 2009
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7X80
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7X7Z
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7X86
 | | The crystal structure of PloI4-F124L in complex with endo-4+2 adduct | | 分子名称: | (4S,4aS,6aR,8R,9R,10aS,13S,14aS,18aR,18bR,E)-9-ethyl-4,8,19-trihydroxy-10a,12,13,18a-tetramethyl-2,3,4,4a,6a,7,8,9,10,10a,13,14,18a,18b-tetradecahydro-14a,17-(metheno)benzo[b]naphtho[2,1-h][1]azacyclododecine-16,18(1H,15H)-dione, PloI4 | | 著者 | Li, M, Pan, L.F. | | 登録日 | 2022-03-11 | | 公開日 | 2023-02-08 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.303 Å) | | 主引用文献 | A cyclase that catalyses competing 2 + 2 and 4 + 2 cycloadditions.
Nat.Chem., 15, 2023
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5WDH
 | | Motor domain of human kinesin family member C1 | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Kinesin-like protein KIFC1, MAGNESIUM ION, ... | | 著者 | Zhu, H, Tempel, W, He, H, Shen, Y, Wang, J, Brothers, G, Landry, R, Arrowsmith, C.H, Edwards, A.M, Park, H, Structural Genomics Consortium (SGC) | | 登録日 | 2017-07-05 | | 公開日 | 2017-08-09 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.248 Å) | | 主引用文献 | Structural basis of small molecule ATPase inhibition of a human mitotic kinesin motor protein.
Sci Rep, 7, 2017
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1OVX
 | | NMR structure of the E. coli ClpX chaperone zinc binding domain dimer | | 分子名称: | ATP-dependent Clp protease ATP-binding subunit clpX, ZINC ION | | 著者 | Donaldson, L.W, Kwan, J, Wojtyra, U, Houry, W.A. | | 登録日 | 2003-03-27 | | 公開日 | 2003-12-30 | | 最終更新日 | 2024-05-01 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of the dimeric zinc binding domain of the chaperone ClpX.
J.Biol.Chem., 278, 2003
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7WCM
 | | Cryo-EM structure of GPR119-Gs Complex with small molecule agonist MBX-2982 | | 分子名称: | 2-[1-(5-ethylpyrimidin-2-yl)piperidin-4-yl]-4-[[4-(1,2,3,4-tetrazol-1-yl)phenoxy]methyl]-1,3-thiazole, Glucose-dependent insulinotropic receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | | 著者 | Qiao, A.N, Wu, S, Ye, S. | | 登録日 | 2021-12-20 | | 公開日 | 2022-12-21 | | 最終更新日 | 2022-12-28 | | 実験手法 | ELECTRON MICROSCOPY (2.33 Å) | | 主引用文献 | Activation and signaling mechanism revealed by GPR119-G s complex structures.
Nat Commun, 13, 2022
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7WCN
 | | Cryo-EM structure of GPR119-Gs Complex with small molecule agonist AR231453 | | 分子名称: | Glucose-dependent insulinotropic receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | | 著者 | Qiao, A.N, Wu, S, Ye, S. | | 登録日 | 2021-12-20 | | 公開日 | 2022-12-21 | | 最終更新日 | 2022-12-28 | | 実験手法 | ELECTRON MICROSCOPY (2.87 Å) | | 主引用文献 | Activation and signaling mechanism revealed by GPR119-G s complex structures.
Nat Commun, 13, 2022
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7X81
 | | The crystal structure of PloI4-C16M/D46A/I137V in complex with exo-2+2 adduct | | 分子名称: | (4S,4aS,6aR,8R,9R,11E,12aR,14aS,17E,18aR,18bR)-9-ethyl-4,8,19-trihydroxy-11,12a,13,18a-tetramethyl-2,3,4,4a,6a,7,8,9,10,12a,13,14,18a,18b-tetradecahydro-14a,17-(metheno)cyclobuta[b]naphtho[2,1-j][1]azacyclotetradecine-16,18(1H,15H)-dione, PloI4 | | 著者 | Li, M, Pan, L.F. | | 登録日 | 2022-03-10 | | 公開日 | 2023-02-08 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.104 Å) | | 主引用文献 | A cyclase that catalyses competing 2 + 2 and 4 + 2 cycloadditions.
Nat.Chem., 15, 2023
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7YW5
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7XIV
 | | Structural insight into the interactions between Lloviu virus VP30 and nucleoprotein | | 分子名称: | Nucleocapsid protein,Minor nucleoprotein VP30 | | 著者 | Dong, S.S, Qin, X.C, Sun, W.Y, Luan, F.C, Wang, J.J, Ma, L, Li, X.X, Yang, G.X, Hao, C.Y. | | 登録日 | 2022-04-14 | | 公開日 | 2022-06-29 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.498 Å) | | 主引用文献 | Structural insights into the interactions between lloviu virus VP30 and nucleoprotein.
Biochem.Biophys.Res.Commun., 616, 2022
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6KVS
 | | Staphylococcus aureus FabH with covalent inhibitor Oxa1 | | 分子名称: | 3-oxoacyl-[acyl-carrier-protein] synthase 3, 4-chloranyl-N-[[cyclopropylmethyl(methanoyl)amino]methyl]benzamide | | 著者 | Yuan, Y, Wang, J. | | 登録日 | 2019-09-05 | | 公開日 | 2020-09-09 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Crystal Structure of S. aureus FabH, beta-ketoacyl carrier protein synthase
To Be Published
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