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6U2F
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PCSK9-Fab 7G7 complex bound to cis-1-amino-4-phenylcyclohexaneacyl-WNLK(hR)IGLLR - NH2
分子名称: 7G7 heavy chain, 7G7 light chain, CALCIUM ION, ...
著者Ultsch, M.H, Kirchhofer, D.
登録日2019-08-19
公開日2020-02-05
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.94 Å)
主引用文献Design of Organo-Peptides As Bipartite PCSK9 Antagonists.
Acs Chem.Biol., 15, 2020
2E8V
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BU of 2e8v by Molmil
S. cerevisiae geranylgeranyl pyrophosphate synthase in complex with product GGPP (P21)
分子名称: GERANYLGERANYL DIPHOSPHATE, Geranylgeranyl pyrophosphate synthetase
著者Chen, C.K.-M, Guo, R.T, Ko, T.P, Jeng, W.Y, Chang, T.H, Liang, P.H, Oldfield, E, Wang, A.H.-J.
登録日2007-01-23
公開日2007-06-12
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Bisphosphonates target multiple sites in both cis- and trans-prenyltransferases
Proc.Natl.Acad.Sci.Usa, 104, 2007
2E92
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BU of 2e92 by Molmil
S. cerevisiae geranylgeranyl pyrophosphate synthase in complex with magnesium and BPH-261
分子名称: (1-HYDROXY-2-IMIDAZO[1,2-A]PYRIDIN-3-YLETHANE-1,1-DIYL)BIS(PHOSPHONIC ACID), Geranylgeranyl pyrophosphate synthetase, MAGNESIUM ION
著者Guo, R.T, Ko, T.P, Cao, R, Jeng, W.Y, Chen, C.K.-M, Chang, T.H, Liang, P.H, Oldfield, E, Wang, A.H.-J.
登録日2007-01-24
公開日2007-06-12
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.31 Å)
主引用文献Bisphosphonates target multiple sites in both cis- and trans-prenyltransferases
Proc.Natl.Acad.Sci.Usa, 104, 2007
8KIH
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BU of 8kih by Molmil
PhmA, a type I diterpene synthase without NST/DTE motif
分子名称: (2Z,6E,10E)-2-fluoro-3,7,11,15-tetramethylhexadeca-2,6,10,14-tetraen-1-yl trihydrogen diphosphate, MAGNESIUM ION, diterpene synthase, ...
著者Zhang, B, Ge, H.M, Zhu, A, Zhang, Y.
登録日2023-08-23
公開日2023-10-04
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Biosynthesis of Platelet Activating Factor Antagonist Phomactins Revealing a New Class of Type I Diterpene Synthase
To Be Published
8KI5
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PhmA, a type I diterpene synthase without NST/DTE motif
分子名称: (2Z,6Z)-3,7,11-trimethyldodeca-2,6,10-trien-1-ol, PhmA
著者Zhang, B, Ge, H.M, Zhu, A, Zhang, Y.
登録日2023-08-22
公開日2023-10-04
実験手法X-RAY DIFFRACTION (2.01 Å)
主引用文献Biosynthesis of Platelet Activating Factor Antagonist Phomactins Revealing a New Class of Type I Diterpene Synthase
To Be Published
6TYE
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BU of 6tye by Molmil
Crystal structure of MTB sigma L transcription initiation complex with 5 nt long RNA primer
分子名称: DNA (5'-D(*GP*CP*AP*TP*CP*CP*GP*TP*GP*AP*AP*TP*CP*GP*AP*GP*G)-3'), DNA (5'-D(P*GP*TP*GP*TP*CP*AP*GP*TP*AP*GP*CP*TP*GP*TP*CP*AP*CP*GP*GP*AP*TP*GP*C)-3'), DNA-directed RNA polymerase subunit alpha, ...
著者Molodtsov, V, Ebright, R.H.
登録日2019-08-08
公開日2020-03-11
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.79 Å)
主引用文献RNA extension drives a stepwise displacement of an initiation-factor structural module in initial transcription.
Proc.Natl.Acad.Sci.USA, 117, 2020
2E8U
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BU of 2e8u by Molmil
S. cerevisiae geranylgeranyl pyrophosphate synthase in complex with magnesium and IPP (P21)
分子名称: 3-METHYLBUT-3-ENYL TRIHYDROGEN DIPHOSPHATE, Geranylgeranyl pyrophosphate synthetase, MAGNESIUM ION
著者Guo, R.T, Chen, C.K.-M, Ko, T.P, Jeng, W.Y, Chang, T.H, Liang, P.H, Oldfield, E, Wang, A.H.-J.
登録日2007-01-23
公開日2007-06-12
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.08 Å)
主引用文献Bisphosphonates target multiple sites in both cis- and trans-prenyltransferases
Proc.Natl.Acad.Sci.Usa, 104, 2007
2E91
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BU of 2e91 by Molmil
S. cerevisiae geranylgeranyl pyrophosphate synthase in complex with magnesium and BPH-91
分子名称: Geranylgeranyl pyrophosphate synthetase, MAGNESIUM ION, ZOLEDRONIC ACID
著者Guo, R.T, Ko, T.P, Cao, R, Chen, C.K.-M, Jeng, W.Y, Chang, T.H, Liang, P.H, Oldfield, E, Wang, A.H.-J.
登録日2007-01-24
公開日2007-06-12
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.14 Å)
主引用文献Bisphosphonates target multiple sites in both cis- and trans-prenyltransferases
Proc.Natl.Acad.Sci.Usa, 104, 2007
6AH3
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BU of 6ah3 by Molmil
Cryo-EM structure of yeast Ribonuclease P with pre-tRNA substrate
分子名称: MAGNESIUM ION, RNases MRP/P 32.9 kDa subunit, Ribonuclease P RNA, ...
著者Lan, P, Tan, M, Wu, J, Lei, M.
登録日2018-08-16
公開日2018-10-17
最終更新日2019-11-06
実験手法ELECTRON MICROSCOPY (3.48 Å)
主引用文献Structural insight into precursor tRNA processing by yeast ribonuclease P.
Science, 362, 2018
6AGB
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BU of 6agb by Molmil
Cryo-EM structure of yeast Ribonuclease P
分子名称: RNases MRP/P 32.9 kDa subunit, Ribonuclease P RNA, Ribonuclease P protein subunit RPR2, ...
著者Lan, P, Tan, M, Wu, J, Lei, M.
登録日2018-08-10
公開日2018-10-17
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (3.48 Å)
主引用文献Structural insight into precursor tRNA processing by yeast ribonuclease P.
Science, 362, 2018
6UYC
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BU of 6uyc by Molmil
Crystal structure of TEAD2 bound to Compound 2
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, N-{5-[(E)-2-(4,4-difluorocyclohexyl)ethenyl]-6-methoxypyridin-3-yl}methanesulfonamide, Transcriptional enhancer factor TEF-4
著者Noland, C.L, Holden, J.K, Crawford, J.J, Zbieg, J.R, Cunningham, C.N.
登録日2019-11-12
公開日2020-06-24
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.658 Å)
主引用文献Small Molecule Dysregulation of TEAD Lipidation Induces a Dominant-Negative Inhibition of Hippo Pathway Signaling.
Cell Rep, 31, 2020
5T8Q
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BU of 5t8q by Molmil
Crystal structure of murine NF-kappaB inducing kinase (NIK) bound to aryl pyrrole fragment 17
分子名称: 1-[(2-chlorophenyl)methyl]pyrrole-2-carboxamide, Mitogen-activated protein kinase kinase kinase 14, SULFATE ION
著者Smith, M.A, McEwan, P.A, Hymowitz, S.G.
登録日2016-09-08
公開日2017-01-11
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.63 Å)
主引用文献Structure-Based Design of Tricyclic NF-kappa B Inducing Kinase (NIK) Inhibitors That Have High Selectivity over Phosphoinositide-3-kinase (PI3K).
J. Med. Chem., 60, 2017
5TDW
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BU of 5tdw by Molmil
Set3 PHD finger in complex with histone H3K4me3
分子名称: SET domain-containing protein 3, SODIUM ION, ZINC ION, ...
著者Andrews, F.H, Ali, M, Kutateladze, T.G.
登録日2016-09-19
公開日2016-10-19
最終更新日2017-06-28
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structural Insight into Recognition of Methylated Histone H3K4 by Set3.
J. Mol. Biol., 429, 2017
7E7Y
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BU of 7e7y by Molmil
Crystal structure of the SARS-CoV-2 S RBD in complex with BD-623 Fab
分子名称: BD-623 Fab H, BD-623 Fab L, Spike protein S1
著者Wei, Y, Xiao, J.
登録日2021-02-28
公開日2021-06-09
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.41 Å)
主引用文献Humoral immune response to circulating SARS-CoV-2 variants elicited by inactivated and RBD-subunit vaccines.
Cell Res., 31, 2021
7E7X
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BU of 7e7x by Molmil
SARS-CoV-2 Spike Protein N terminal domain in Complex with N11 Fab
分子名称: N11 Fab Light chain, N11 Fab heavy chain, Spike protein S1
著者Zhang, Z, Shuo, D, Xiao, J.
登録日2021-02-28
公開日2021-06-09
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.78 Å)
主引用文献Humoral immune response to circulating SARS-CoV-2 variants elicited by inactivated and RBD-subunit vaccines.
Cell Res., 31, 2021
7E8C
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BU of 7e8c by Molmil
SARS-CoV-2 S-6P in complex with 9 Fabs
分子名称: 368-2 H, 368-2 L, 604 H, ...
著者Du, S, Xiao, J, Zhang, Z.
登録日2021-03-01
公開日2021-06-09
最終更新日2021-07-14
実験手法ELECTRON MICROSCOPY (3.16 Å)
主引用文献Humoral immune response to circulating SARS-CoV-2 variants elicited by inactivated and RBD-subunit vaccines.
Cell Res., 31, 2021
7E88
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BU of 7e88 by Molmil
Crystal structure of the SARS-CoV-2 S RBD in complex with BD-515 Fab
分子名称: BD-515 Fab Heavy Chain, BD-515 Fab Light Chain, Spike protein S1
著者Gao, C, Wei, Y, Xiao, J.
登録日2021-03-01
公開日2021-06-09
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (3.14 Å)
主引用文献Humoral immune response to circulating SARS-CoV-2 variants elicited by inactivated and RBD-subunit vaccines.
Cell Res., 31, 2021
7E8F
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BU of 7e8f by Molmil
SARS-CoV-2 NTD in complex with N9 Fab
分子名称: 368-2 H, 368-2 L, 604 H, ...
著者Du, S, Xiao, J, Zhang, Z.
登録日2021-03-01
公開日2021-06-09
最終更新日2021-07-14
実験手法ELECTRON MICROSCOPY (3.18 Å)
主引用文献Humoral immune response to circulating SARS-CoV-2 variants elicited by inactivated and RBD-subunit vaccines.
Cell Res., 31, 2021
7E86
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BU of 7e86 by Molmil
Crystal structure of the SARS-CoV-2 S RBD in complex with BD-508 Fab
分子名称: BD-508 Fab Heavy Chain, BD-508 Fab Light Chain, Spike protein S1
著者Gao, C, Xiao, J.
登録日2021-03-01
公開日2021-06-09
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Humoral immune response to circulating SARS-CoV-2 variants elicited by inactivated and RBD-subunit vaccines.
Cell Res., 31, 2021
5SVX
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BU of 5svx by Molmil
MORC3 CW in complex with histone H3K4me3
分子名称: H3K4me3, MORC family CW-type zinc finger protein 3, ZINC ION
著者Tong, Q, Andrews, F.H, Kutateladze, T.G.
登録日2016-08-08
公開日2016-10-05
実験手法X-RAY DIFFRACTION (1.56 Å)
主引用文献Multivalent Chromatin Engagement and Inter-domain Crosstalk Regulate MORC3 ATPase.
Cell Rep, 16, 2016
5SVY
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BU of 5svy by Molmil
MORC3 CW in complex with histone H3K4me1
分子名称: ACETATE ION, H3K4me1, MORC family CW-type zinc finger protein 3, ...
著者Tong, Q, Andrews, F.H, Kutateladze, T.G.
登録日2016-08-08
公開日2016-10-05
実験手法X-RAY DIFFRACTION (1.05 Å)
主引用文献Multivalent Chromatin Engagement and Inter-domain Crosstalk Regulate MORC3 ATPase.
Cell Rep, 16, 2016
6UYB
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BU of 6uyb by Molmil
Crystal structure of TEAD2 bound to Compound 1
分子名称: (3R,4R)-1-{3-[(E)-2-(4-chlorophenyl)ethenyl]-4-methoxy-5-methylphenyl}-3,4-dihydroxypyrrolidin-2-one, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, GLYCEROL, ...
著者Noland, C.L, Holden, J.K, Crawford, J.J, Zbieg, J.R, Cunningham, C.N.
登録日2019-11-12
公開日2020-06-24
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.543 Å)
主引用文献Small Molecule Dysregulation of TEAD Lipidation Induces a Dominant-Negative Inhibition of Hippo Pathway Signaling.
Cell Rep, 31, 2020
5SVI
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BU of 5svi by Molmil
MORC3 CW domain in complex with unmodified histone H3
分子名称: ALA-ARG-THR-LYS-GLN-THR-ALA-ARG, MORC family CW-type zinc finger protein 3, ZINC ION
著者Tong, Q, Andrews, F.H, Kutateladze, T.G.
登録日2016-08-06
公開日2016-12-14
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.613 Å)
主引用文献Multivalent Chromatin Engagement and Inter-domain Crosstalk Regulate MORC3 ATPase.
Cell Rep, 16, 2016
7WHK
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BU of 7whk by Molmil
The state 3 complex structure of Omicron spike with Bn03 (2-up RBD, 5 nanobodies)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Bn03_nano1, Bn03_nano2, ...
著者Zhan, W.Q, Zhang, X, Chen, Z.G, Sun, L.
登録日2021-12-30
公開日2022-05-11
実験手法ELECTRON MICROSCOPY (3.01 Å)
主引用文献Broad neutralization of SARS-CoV-2 variants by an inhalable bispecific single-domain antibody.
Cell, 185, 2022
7WHI
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The state 2 complex structure of Omicron spike with Bn03 (2-up RBD, 4 nanobodies)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Bn03_nano1, Bn03_nano2, ...
著者Zhan, W.Q, Zhang, X, Chen, Z.G, Sun, L.
登録日2021-12-30
公開日2022-05-11
実験手法ELECTRON MICROSCOPY (2.93 Å)
主引用文献Broad neutralization of SARS-CoV-2 variants by an inhalable bispecific single-domain antibody.
Cell, 185, 2022

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