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8ORE
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BU of 8ore by Molmil
Cryo-EM structure of SH-SY5Y seeded with filaments from Alzheimer's Disease
分子名称: Microtubule-associated protein tau
著者Lovestam, S, Scheres, S.H.W, Goedert, M.
登録日2023-04-13
公開日2023-04-26
最終更新日2024-07-24
実験手法ELECTRON MICROSCOPY (2.5 Å)
主引用文献Cryo-EM structures of tau filaments from SH-SY5Y cells seeded with brain extracts from cases of Alzheimer's disease and corticobasal degeneration.
Febs Open Bio, 13, 2023
5Z8S
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BU of 5z8s by Molmil
Human Mitochondrial ferritin mutant - C102A/C130A/E27C/E61C/E62C
分子名称: Ferritin, mitochondrial, GOLD ION
著者Zang, J, Zheng, B, Zhao, G.
登録日2018-02-01
公開日2019-02-06
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (1.973 Å)
主引用文献Design and site-directed compartmentalization of gold nanoclusters within the intrasubunit interfaces of ferritin nanocage.
J Nanobiotechnology, 17, 2019
5Z91
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BU of 5z91 by Molmil
Human mitochondrial ferritin mutant bound with gold ions
分子名称: Ferritin, mitochondrial, GOLD ION, ...
著者Zang, J, Zheng, B, Zhao, G.
登録日2018-02-01
公開日2019-02-06
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (3.004 Å)
主引用文献Design and site-directed compartmentalization of gold nanoclusters within the intrasubunit interfaces of ferritin nanocage.
J Nanobiotechnology, 17, 2019
5Z8U
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BU of 5z8u by Molmil
Human mitochondrial ferritin mutant - C102A/C130A
分子名称: Ferritin, mitochondrial, MAGNESIUM ION
著者Zang, J, Zheng, B, Zhao, G.
登録日2018-02-01
公開日2019-02-06
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Design and site-directed compartmentalization of gold nanoclusters within the intrasubunit interfaces of ferritin nanocage.
J Nanobiotechnology, 17, 2019
4I0T
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BU of 4i0t by Molmil
Crystal structure of spleen tyrosine kinase complexed with 2-(5,6,7,8-Tetrahydro-imidazo[1,5-a]pyridin-1-yl)-5H-pyrrolo[2,3-b]pyrazine-7-carboxylic acid tert-butylamide
分子名称: N-tert-butyl-2-(5,6,7,8-tetrahydroimidazo[1,5-a]pyridin-1-yl)-5H-pyrrolo[2,3-b]pyrazine-7-carboxamide, Tyrosine-protein kinase SYK
著者Kuglstatter, A, Slade, M.
登録日2012-11-19
公開日2013-10-30
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Pyrrolopyrazines as selective spleen tyrosine kinase inhibitors.
J.Med.Chem., 56, 2013
7E0F
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BU of 7e0f by Molmil
CryoEM structure of G51D alpha-synuclein amyloid fibril
分子名称: Alpha-synuclein
著者Sun, Y.P, Long, H.F, Xia, W.C, Liu, C.
登録日2021-01-27
公開日2021-10-06
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (3.02 Å)
主引用文献The hereditary mutation G51D unlocks a distinct fibril strain transmissible to wild-type alpha-synuclein.
Nat Commun, 12, 2021
7EKQ
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BU of 7ekq by Molmil
CrClpP-S2c
分子名称: ATP-dependent Clp protease ATP-binding subunit CLPT4, chloroplastic, ATP-dependent Clp protease proteolytic subunit, ...
著者Wang, N, Wang, Y.F, Cong, Y, Liu, C.M.
登録日2021-04-06
公開日2021-10-20
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献The cryo-EM structure of the chloroplast ClpP complex.
Nat.Plants, 7, 2021
7EKO
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BU of 7eko by Molmil
CrClpP-S1
分子名称: ATP-dependent Clp protease ATP-binding subunit CLPT4, chloroplastic, ATP-dependent Clp protease proteolytic subunit
著者Wang, N, Wang, Y.F, Cong, Y, Liu, C.M.
登録日2021-04-06
公開日2021-10-20
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献The cryo-EM structure of the chloroplast ClpP complex.
Nat.Plants, 7, 2021
7LC3
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BU of 7lc3 by Molmil
CryoEM Structure of KdpFABC in E1-ATP state
分子名称: (2R)-3-(((2-aminoethoxy)(hydroxy)phosphoryl)oxy)-2-(palmitoyloxy)propyl (E)-octadec-9-enoate, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, ...
著者Sweet, M.E, Larsen, C, Pedersen, B.P, Stokes, D.L.
登録日2021-01-09
公開日2021-01-27
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (3.23 Å)
主引用文献Structural basis for potassium transport in prokaryotes by KdpFABC.
Proc.Natl.Acad.Sci.USA, 118, 2021
5Z8J
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BU of 5z8j by Molmil
Human mitochondrial ferritin mutant - E27C/E62C/C102G/C130G
分子名称: Ferritin, mitochondrial, GOLD ION
著者Zang, J, Zheng, B, Zhao, G.
登録日2018-01-31
公開日2019-02-06
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Design and site-directed compartmentalization of gold nanoclusters within the intrasubunit interfaces of ferritin nanocage.
J Nanobiotechnology, 17, 2019
4JIK
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BU of 4jik by Molmil
X-RAY Crystal structure of compound 22a (R)-2-(4-chlorophenyl)-8-(piperidin-3-ylamino)imidazo[1,2-c]pyrimidine-5-carboxamide bound to human chk1 kinase domain
分子名称: 2-(4-chlorophenyl)-8-[(3S)-piperidin-3-ylamino]imidazo[1,2-c]pyrimidine-5-carboxamide, Serine/threonine-protein kinase Chk1
著者Fischmann, T.O.
登録日2013-03-06
公開日2013-04-17
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Potency switch between CHK1 and MK2: discovery of imidazo[1,2-a]pyrazine- and imidazo[1,2-c]pyrimidine-based kinase inhibitors.
Bioorg.Med.Chem.Lett., 23, 2013
1Q5X
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BU of 1q5x by Molmil
Structure of OF RRAA (MENG), a protein inhibitor of RNA processing
分子名称: REGULATOR OF RNASE E ACTIVITY A
著者Monzingo, A.F, Gao, J, Qiu, J, Georgiou, G, Robertus, J.D.
登録日2003-08-11
公開日2003-09-30
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献The X-ray Structure of Escherichia coli RraA (MenG), A Protein Inhibitor of RNA Processing.
J.Mol.Biol., 332, 2003
7ELT
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BU of 7elt by Molmil
Crystal structure of Mycobacterium tuberculosis tryptophanyl-tRNA synthetase complexed with Trp-AMP
分子名称: TRYPTOPHANYL-5'AMP, Tryptophan--tRNA ligase
著者Xu, M, Chen, S.
登録日2021-04-12
公開日2022-02-16
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Investigate Natural Product Indolmycin and the Synthetically Improved Analogue Toward Antimycobacterial Agents.
Acs Chem.Biol., 17, 2022
7EL8
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BU of 7el8 by Molmil
Crystal structure of Mycobacterium tuberculosis tryptophanyl-tRNA synthetase
分子名称: Tryptophan--tRNA ligase
著者Xu, M, Chen, S.
登録日2021-04-09
公開日2022-02-16
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Investigate Natural Product Indolmycin and the Synthetically Improved Analogue Toward Antimycobacterial Agents.
Acs Chem.Biol., 17, 2022
7ENS
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BU of 7ens by Molmil
Crystal structure of Mycobacterium tuberculosis tryptophanyl-tRNA synthetase complexed with Indolmycin and ATP
分子名称: (5S)-5-[(1R)-1-(1H-indol-3-yl)ethyl]-2-(methylamino)-1,3-oxazol-4(5H)-one, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
著者Xu, M, Chen, S.
登録日2021-04-19
公開日2022-02-16
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Investigate Natural Product Indolmycin and the Synthetically Improved Analogue Toward Antimycobacterial Agents.
Acs Chem.Biol., 17, 2022
7ENT
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BU of 7ent by Molmil
Crystal structure of Mycobacterium tuberculosis tryptophanyl-tRNA synthetase complexed with Y-13 and ATP
分子名称: (5S)-2-(methylamino)-5-[(1R)-1-(4-methyl-1H-indol-3-yl)ethyl]-1,3-oxazol-4-one, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
著者Xu, M, Chen, S.
登録日2021-04-19
公開日2022-02-16
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Investigate Natural Product Indolmycin and the Synthetically Improved Analogue Toward Antimycobacterial Agents.
Acs Chem.Biol., 17, 2022
4O6F
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BU of 4o6f by Molmil
Structural Basis of Estrogen Receptor Alpha Methylation Mediated by Histone Methyltransferase SmyD2
分子名称: 3,6,9,12,15,18,21-HEPTAOXATRICOSANE-1,23-DIOL, Estrogen receptor, N-lysine methyltransferase SMYD2, ...
著者Jiang, Y, Trescott, L, Holcomb, J, Brunzelle, J, Sirinupong, N, Shi, X, Yang, Z.
登録日2013-12-20
公開日2014-03-26
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.822 Å)
主引用文献Structural Insights into Estrogen Receptor alpha Methylation by Histone Methyltransferase SMYD2, a Cellular Event Implicated in Estrogen Signaling Regulation.
J.Mol.Biol., 426, 2014
5XZ9
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BU of 5xz9 by Molmil
Crystal Structure of Phosphofructokinase from Staphylococcus aureus in complex with adenylylimidodiphosphate, the ATP analogue
分子名称: ADENOSINE-5'-TRIPHOSPHATE, ATP-dependent 6-phosphofructokinase, GLYCEROL
著者Wang, C.L, Tian, T, Zang, J.Y.
登録日2017-07-12
公開日2019-03-13
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural Insights into the Regulation of Staphylococcus aureus Phosphofructokinase by Tetramer-Dimer Conversion.
Biochemistry, 57, 2018
5XZ7
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BU of 5xz7 by Molmil
Crystal Structure of Phosphofructokinase from Staphylococcus aureus in complex with adenylylimidodiphosphate, the ATP analogue
分子名称: 6-O-phosphono-beta-D-fructofuranose, ATP-dependent 6-phosphofructokinase, DI(HYDROXYETHYL)ETHER, ...
著者Wang, C.L, Tian, T, Zang, J.Y.
登録日2017-07-11
公開日2019-03-13
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structural Insights into the Regulation of Staphylococcus aureus Phosphofructokinase by Tetramer-Dimer Conversion.
Biochemistry, 57, 2018
4I0S
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BU of 4i0s by Molmil
Crystal structure of spleen tyrosine kinase complexed with 2-(6-Chloro-1-methyl-1H-indazol-3-yl)-5H-pyrrolo[2,3-b]pyrazine-7-carboxylic acid isopropylamide
分子名称: 2-(6-chloro-1-methyl-1H-indazol-3-yl)-N-(propan-2-yl)-5H-pyrrolo[2,3-b]pyrazine-7-carboxamide, Tyrosine-protein kinase SYK
著者Kuglstatter, A, Slade, M.
登録日2012-11-19
公開日2013-10-30
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.98 Å)
主引用文献Pyrrolopyrazines as selective spleen tyrosine kinase inhibitors.
J.Med.Chem., 56, 2013
4HRE
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BU of 4hre by Molmil
Crystal Structure of p11/Annexin A2 Heterotetramer in Complex with SMARCA3 Peptide
分子名称: Annexin A2, Helicase-like transcription factor, Protein S100-A10
著者Gao, P, Patel, D.J.
登録日2012-10-27
公開日2013-03-06
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.7852 Å)
主引用文献SMARCA3, a Chromatin-Remodeling Factor, Is Required for p11-Dependent Antidepressant Action.
Cell(Cambridge,Mass.), 152, 2013
4HRH
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Crystal Structure of p11-Annexin A2(N-terminal) Fusion Protein in Complex with SMARCA3 Peptide
分子名称: Helicase-like transcription factor, Protein S100-A10, Annexin A2, ...
著者Gao, P, Patel, D.J.
登録日2012-10-27
公開日2013-03-06
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3.001 Å)
主引用文献SMARCA3, a Chromatin-Remodeling Factor, Is Required for p11-Dependent Antidepressant Action.
Cell(Cambridge,Mass.), 152, 2013
4I0R
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BU of 4i0r by Molmil
Crystal structure of spleen tyrosine kinase complexed with 2-(3,4,5-Trimethoxy-phenyl)-5H-pyrrolo[2,3-b]pyrazine-7-carboxylic acid isopropylamide
分子名称: N-(propan-2-yl)-2-(3,4,5-trimethoxyphenyl)-5H-pyrrolo[2,3-b]pyrazine-7-carboxamide, Tyrosine-protein kinase SYK
著者Kuglstatter, A, Villasenor, A.G.
登録日2012-11-19
公開日2013-10-30
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Pyrrolopyrazines as selective spleen tyrosine kinase inhibitors.
J.Med.Chem., 56, 2013
5XLP
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BU of 5xlp by Molmil
Anti-CRISPR proteins AcrF1/2 bound to Csy surveillance complex with a 20nt spacer crRNA backbone region
分子名称: CRISPR-associated protein Csy3, Uncharacterized protein AcrF1, crRNA with 20nt spacer sequence
著者Peng, R, Shi, Y, Gao, G.F.
登録日2017-05-11
公開日2018-01-10
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献Alternate binding modes of anti-CRISPR viral suppressors AcrF1/2 to Csy surveillance complex revealed by cryo-EM structures.
Cell Res., 27, 2017
7BH1
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BU of 7bh1 by Molmil
Cryo-EM Structure of KdpFABC in E1 state with K
分子名称: (2R)-3-(((2-aminoethoxy)(hydroxy)phosphoryl)oxy)-2-(palmitoyloxy)propyl (E)-octadec-9-enoate, POTASSIUM ION, Potassium-transporting ATPase ATP-binding subunit, ...
著者Sweet, M.E, Larsen, C, Pedersen, B.P, Stokes, D.L.
登録日2021-01-09
公開日2021-01-27
最終更新日2024-07-10
実験手法ELECTRON MICROSCOPY (3.38 Å)
主引用文献Structural basis for potassium transport in prokaryotes by KdpFABC.
Proc.Natl.Acad.Sci.USA, 118, 2021

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