5CF3
 
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5DGH
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5UI8
 | | structure of sigmaN-holoenzyme | | 分子名称: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | | 著者 | Darst, S.A, Campbell, E.A. | | 登録日 | 2017-01-13 | | 公開日 | 2017-02-22 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (3.76 Å) | | 主引用文献 | Crystal structure of Aquifex aeolicus sigma (N) bound to promoter DNA and the structure of sigma (N)-holoenzyme.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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2LGW
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5XEX
 | | Crystal structure of S.aureus PNPase catalytic domain | | 分子名称: | DI(HYDROXYETHYL)ETHER, GLYCEROL, PYROPHOSPHATE, ... | | 著者 | Wang, X, Zhang, X, Zang, J. | | 登録日 | 2017-04-06 | | 公開日 | 2017-10-18 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Enolase binds to RnpA in competition with PNPase in Staphylococcus aureus
FEBS Lett., 591, 2017
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5XLP
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5XOE
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5XDZ
 | | Crystal structure of zebrafish SNX25 PX domain | | 分子名称: | CHLORIDE ION, Cellular trafficking protein, SODIUM ION | | 著者 | Su, K, Zhang, Y, Xu, J, Liu, J. | | 登録日 | 2017-03-30 | | 公開日 | 2017-06-14 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Structure of the PX domain of SNX25 reveals a novel phospholipid recognition model by dimerization in the PX domain
FEBS Lett., 591, 2017
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5XLO
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5Y5W
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5YZ3
 | | Crystal structure of T2R-TTL-28 complex | | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, CHLORIDE ION, ... | | 著者 | Yu, Y, Chen, Q. | | 登録日 | 2017-12-12 | | 公開日 | 2018-10-24 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.545 Å) | | 主引用文献 | A Novel Microtubule Inhibitor Overcomes Multidrug Resistance in Tumors.
Cancer Res., 78, 2018
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2IF2
 | | Crystal Structure of the Putative Dephospho-CoA Kinase from Aquifex aeolicus, Northeast Structural Genomics Target QR72. | | 分子名称: | 1,2-ETHANEDIOL, Dephospho-CoA kinase, SULFATE ION | | 著者 | Forouhar, F, Hussain, M, Seetharaman, J, Hussain, A, Wu, M, Fang, Y, Cunningham, K, Ma, L.C, Xiao, R, Liu, J, Baran, M, Rost, B, Acton, T.B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) | | 登録日 | 2006-09-19 | | 公開日 | 2006-10-03 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 |
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4JA8
 | | Complex of Mitochondrial Isocitrate Dehydrogenase R140Q Mutant with AGI-6780 Inhibitor | | 分子名称: | 1-[5-(cyclopropylsulfamoyl)-2-thiophen-3-yl-phenyl]-3-[3-(trifluoromethyl)phenyl]urea, CALCIUM ION, GLYCEROL, ... | | 著者 | Wei, W, Chen, L, Wu, M, Jiang, F, Travins, J, Qian, K, DeLaBarre, B. | | 登録日 | 2013-02-18 | | 公開日 | 2013-04-10 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | | 主引用文献 | Targeted inhibition of mutant IDH2 in leukemia cells induces cellular differentiation.
Science, 340, 2013
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4QBA
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6IXL
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6IXN
 | | Crystal structure of isocitrate dehydrogenase from Ostreococcus tauri in complex with NAD+ and citrate | | 分子名称: | CITRATE ANION, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... | | 著者 | Zhu, G.P, Tang, W.G, Wang, P. | | 登録日 | 2018-12-11 | | 公開日 | 2019-12-18 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (1.87 Å) | | 主引用文献 | Crystal structures of NAD + -linked isocitrate dehydrogenase from the green alga Ostreococcus tauri and its evolutionary relationship with eukaryotic NADP + -linked homologs.
Arch.Biochem.Biophys., 708, 2021
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6IXT
 | | Crystal structure of isocitrate dehydrogenase from Ostreococcus tauri in complex with NAD+ and Mg2+ | | 分子名称: | GLYCEROL, Isocitrate dehydrogenase, MAGNESIUM ION, ... | | 著者 | Zhu, G.P, Tang, W.G, Wang, P. | | 登録日 | 2018-12-12 | | 公開日 | 2019-12-18 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (1.78 Å) | | 主引用文献 | Crystal structures of NAD + -linked isocitrate dehydrogenase from the green alga Ostreococcus tauri and its evolutionary relationship with eukaryotic NADP + -linked homologs.
Arch.Biochem.Biophys., 708, 2021
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6JQX
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6JQW
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6JQ2
 | | Crystal Structure of H2-Kb in complex with a DPAGT1 self-peptide | | 分子名称: | Beta-2-microglobulin, DPATG1 antigen SIIVFNLV, H-2 class I histocompatibility antigen, ... | | 著者 | Bai, P, Yin, L. | | 登録日 | 2019-03-28 | | 公開日 | 2020-04-01 | | 最終更新日 | 2021-02-17 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Immune-based mutation classification enables neoantigen prioritization and immune feature discovery in cancer immunotherapy.
Oncoimmunology, 10, 2021
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6JQ3
 | | Crystal Structure of H2-Kb in complex with a DPAGT1 mutant peptide | | 分子名称: | Beta-2-microglobulin, DPAGT1 mutant antigen SIIVFNLL, H-2 class I histocompatibility antigen, ... | | 著者 | Bai, P, Zhou, Q, Wei, P, Yin, L. | | 登録日 | 2019-03-28 | | 公開日 | 2020-05-06 | | 最終更新日 | 2021-02-17 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Immune-based mutation classification enables neoantigen prioritization and immune feature discovery in cancer immunotherapy.
Oncoimmunology, 10, 2021
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6JTN
 | | Crystal structure of HLA-C08 in complex with a tumor mut10m peptide | | 分子名称: | 10-mer peptide, Beta-2-microglobulin, HLA class I antigen, ... | | 著者 | Bai, P, Zhou, Q, Wei, P, Yin, L. | | 登録日 | 2019-04-11 | | 公開日 | 2020-04-15 | | 最終更新日 | 2021-02-17 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Immune-based mutation classification enables neoantigen prioritization and immune feature discovery in cancer immunotherapy.
Oncoimmunology, 10, 2021
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6JTP
 | | Crystal structure of HLA-C08 in complex with a tumor mut9m peptide | | 分子名称: | 9-mer peptide, Beta-2-microglobulin, HLA class I antigen, ... | | 著者 | Bai, P, Zhou, Q, Wei, P, Lei, Y. | | 登録日 | 2019-04-11 | | 公開日 | 2020-04-15 | | 最終更新日 | 2021-02-17 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Immune-based mutation classification enables neoantigen prioritization and immune feature discovery in cancer immunotherapy.
Oncoimmunology, 10, 2021
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7E2W
 | | Crystal structure of isocitrate dehydrogenase from Ostreococcus tauri in complex with isocitrate and magnesium(II) | | 分子名称: | CITRATE ANION, GLYCEROL, ISOCITRIC ACID, ... | | 著者 | Zhu, G.P, Tang, W.G, Wang, P. | | 登録日 | 2021-02-07 | | 公開日 | 2021-05-19 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Crystal structures of NAD + -linked isocitrate dehydrogenase from the green alga Ostreococcus tauri and its evolutionary relationship with eukaryotic NADP + -linked homologs.
Arch.Biochem.Biophys., 708, 2021
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7FAY
 | | Crystal structure of SARS-CoV-2 main protease in complex with (R)-1a | | 分子名称: | (2~{R})-~{N}-[(1~{R})-2-(~{tert}-butylamino)-2-oxidanylidene-1-pyridin-3-yl-ethyl]-~{N}-(4-~{tert}-butylphenyl)-2-oxidanyl-propanamide, 3C-like proteinase | | 著者 | Zeng, R, Quan, B.X, Liu, X.L, Lei, J. | | 登録日 | 2021-07-08 | | 公開日 | 2021-07-21 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | An orally available M pro inhibitor is effective against wild-type SARS-CoV-2 and variants including Omicron.
Nat Microbiol, 7, 2022
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