7ROT
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![BU of 7rot by Molmil](/molmil-images/mine/7rot) | Plasmodium falciparum tyrosyl-tRNA synthetase, S234C mutant, in complex with ML901-Tyr | 分子名称: | CHLORIDE ION, MAGNESIUM ION, Tyrosine--tRNA ligase, ... | 著者 | Metcalfe, R.D, Xie, S.C, Morton, C.J, Tilley, L, Griffin, M.D.W. | 登録日 | 2021-08-02 | 公開日 | 2022-06-08 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Reaction hijacking of tyrosine tRNA synthetase as a new whole-of-life-cycle antimalarial strategy. Science, 376, 2022
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6MUW
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![BU of 6muw by Molmil](/molmil-images/mine/6muw) | The structure of the Plasmodium falciparum 20S proteasome. | 分子名称: | 20S proteasome alpha-1 subunit, 20S proteasome alpha-2 subunit, 20S proteasome alpha-3 subunit, ... | 著者 | Metcalfe, R.D, Xie, S.C, Hanssen, E, Gillett, D.L, Leis, A.P, Tilley, L, Griffin, M.D.W. | 登録日 | 2018-10-23 | 公開日 | 2019-08-07 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | The structure of the PA28-20S proteasome complex from Plasmodium falciparum and implications for proteostasis. Nat Microbiol, 4, 2019
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6MUX
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![BU of 6mux by Molmil](/molmil-images/mine/6mux) | The structure of the Plasmodium falciparum 20S proteasome in complex with one PA28 activator | 分子名称: | 20S proteasome alpha-1 subunit, 20S proteasome alpha-2 subunit, 20S proteasome alpha-3 subunit, ... | 著者 | Metcalfe, R.D, Xie, S.C, Hanssen, E, Gillett, D.L, Leis, A.P, Tilley, L, Griffin, M.D.W. | 登録日 | 2018-10-23 | 公開日 | 2019-08-07 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | The structure of the PA28-20S proteasome complex from Plasmodium falciparum and implications for proteostasis. Nat Microbiol, 4, 2019
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6O4P
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![BU of 6o4p by Molmil](/molmil-images/mine/6o4p) | The crystal structure of the interleukin 11 alpha receptor | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-11 receptor subunit alpha, ... | 著者 | Aizel, K, Metcalfe, R.D, Griffin, M.D.W. | 登録日 | 2019-02-28 | 公開日 | 2020-05-06 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (3.429 Å) | 主引用文献 | The structure of the extracellular domains of human interleukin 11 alpha receptor reveals mechanisms of cytokine engagement. J.Biol.Chem., 295, 2020
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6MUV
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![BU of 6muv by Molmil](/molmil-images/mine/6muv) | The structure of the Plasmodium falciparum 20S proteasome in complex with two PA28 activators | 分子名称: | 20S proteasome alpha-1 subunit, 20S proteasome alpha-2 subunit, 20S proteasome alpha-3 subunit, ... | 著者 | Metcalfe, R.D, Xie, S.C, Hanssen, E, Gillett, D.L, Leis, A.P, Tilley, L, Griffin, M.D.W. | 登録日 | 2018-10-23 | 公開日 | 2019-08-07 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | The structure of the PA28-20S proteasome complex from Plasmodium falciparum and implications for proteostasis. Nat Microbiol, 4, 2019
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6O4O
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![BU of 6o4o by Molmil](/molmil-images/mine/6o4o) | The structure of human interleukin 11 | 分子名称: | CHLORIDE ION, Interleukin-11, SULFATE ION | 著者 | Metcalfe, R.D, Griffin, M.D.W. | 登録日 | 2019-02-28 | 公開日 | 2020-05-06 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.62 Å) | 主引用文献 | The structure of the extracellular domains of human interleukin 11 alpha receptor reveals mechanisms of cytokine engagement. J.Biol.Chem., 295, 2020
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8DPU
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![BU of 8dpu by Molmil](/molmil-images/mine/8dpu) | The crystal structure of the IL-11 signalling complex | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-11, ... | 著者 | Metcalfe, R.D, Aizel, K, Griffin, M.D.W. | 登録日 | 2022-07-17 | 公開日 | 2023-11-29 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (3.78 Å) | 主引用文献 | Structures of the interleukin 11 signalling complex reveal gp130 dynamics and the inhibitory mechanism of a cytokine variant. Nat Commun, 14, 2023
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8DPT
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![BU of 8dpt by Molmil](/molmil-images/mine/8dpt) | The structure of the IL-11 signalling complex, with full-length extracellular gp130 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-11, ... | 著者 | Metcalfe, R.D, Hanssen, E, Griffin, M.D.W. | 登録日 | 2022-07-17 | 公開日 | 2023-11-29 | 最終更新日 | 2024-05-01 | 実験手法 | ELECTRON MICROSCOPY (4 Å) | 主引用文献 | Structures of the interleukin 11 signalling complex reveal gp130 dynamics and the inhibitory mechanism of a cytokine variant. Nat Commun, 14, 2023
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8DPV
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![BU of 8dpv by Molmil](/molmil-images/mine/8dpv) | |
8DPW
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![BU of 8dpw by Molmil](/molmil-images/mine/8dpw) | |
8DPS
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![BU of 8dps by Molmil](/molmil-images/mine/8dps) | The structure of the interleukin 11 signalling complex, truncated gp130 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-11, ... | 著者 | Metcalfe, R.D, Hanssen, E, Griffin, M.D.W. | 登録日 | 2022-07-17 | 公開日 | 2023-11-29 | 最終更新日 | 2024-05-01 | 実験手法 | ELECTRON MICROSCOPY (3.47 Å) | 主引用文献 | Structures of the interleukin 11 signalling complex reveal gp130 dynamics and the inhibitory mechanism of a cytokine variant. Nat Commun, 14, 2023
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3VFL
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![BU of 3vfl by Molmil](/molmil-images/mine/3vfl) | |
2FMA
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![BU of 2fma by Molmil](/molmil-images/mine/2fma) | |
3LE0
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![BU of 3le0 by Molmil](/molmil-images/mine/3le0) | Lectin Domain of Lectinolysin complexed with Glycerol | 分子名称: | CALCIUM ION, GLYCEROL, NICKEL (II) ION, ... | 著者 | Feil, S.C. | 登録日 | 2010-01-13 | 公開日 | 2010-12-29 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.91 Å) | 主引用文献 | Structure of the lectin regulatory domain of the cholesterol-dependent cytolysin lectinolysin reveals the basis for its lewis antigen specificity. Structure, 20, 2012
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3LEG
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![BU of 3leg by Molmil](/molmil-images/mine/3leg) | Lectin Domain of Lectinolysin complexed with Lewis Y Antigen | 分子名称: | CALCIUM ION, NICKEL (II) ION, Platelet aggregation factor Sm-hPAF, ... | 著者 | Feil, S.C. | 登録日 | 2010-01-14 | 公開日 | 2010-12-29 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.01 Å) | 主引用文献 | Structure of the lectin regulatory domain of the cholesterol-dependent cytolysin lectinolysin reveals the basis for its lewis antigen specificity. Structure, 20, 2012
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3LEK
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![BU of 3lek by Molmil](/molmil-images/mine/3lek) | Lectin Domain of Lectinolysin complexed with Lewis B Antigen | 分子名称: | CALCIUM ION, NICKEL (II) ION, Platelet aggregation factor Sm-hPAF, ... | 著者 | Feil, S.C. | 登録日 | 2010-01-15 | 公開日 | 2010-12-29 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structure of the lectin regulatory domain of the cholesterol-dependent cytolysin lectinolysin reveals the basis for its lewis antigen specificity. Structure, 20, 2012
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5EZV
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![BU of 5ezv by Molmil](/molmil-images/mine/5ezv) | |
3C0N
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![BU of 3c0n by Molmil](/molmil-images/mine/3c0n) | Crystal structure of the proaerolysin mutant Y221G at 2.2 A | 分子名称: | Aerolysin | 著者 | Pernot, L, Schiltz, M, Thurnheer, S, Burr, S.E, van der Goot, G. | 登録日 | 2008-01-21 | 公開日 | 2008-02-12 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Molecular assembly of the aerolysin pore reveals a swirling membrane-insertion mechanism. Nat.Chem.Biol., 9, 2013
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3C0O
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![BU of 3c0o by Molmil](/molmil-images/mine/3c0o) | Crystal structure of the proaerolysin mutant Y221G complexed with mannose-6-phosphate | 分子名称: | 6-O-phosphono-alpha-D-mannopyranose, ACETATE ION, Aerolysin | 著者 | Pernot, L, Schiltz, M, Thurnheer, S, Burr, S.E, van der Goot, G. | 登録日 | 2008-01-21 | 公開日 | 2008-02-12 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Molecular assembly of the aerolysin pore reveals a swirling membrane-insertion mechanism. Nat.Chem.Biol., 9, 2013
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3C0M
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![BU of 3c0m by Molmil](/molmil-images/mine/3c0m) | Crystal structure of the proaerolysin mutant Y221G | 分子名称: | Aerolysin | 著者 | Pernot, L, Schiltz, M, Thurnheer, S, Burr, S.E, van der Goot, G. | 登録日 | 2008-01-21 | 公開日 | 2008-02-12 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.88 Å) | 主引用文献 | Molecular assembly of the aerolysin pore reveals a swirling membrane-insertion mechanism. Nat.Chem.Biol., 9, 2013
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3EIN
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![BU of 3ein by Molmil](/molmil-images/mine/3ein) | Delta class GST | 分子名称: | GLUTATHIONE, Glutathione S-transferase 1-1 | 著者 | Feil, S.C. | 登録日 | 2008-09-17 | 公開日 | 2009-09-01 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (1.126 Å) | 主引用文献 | Probing insect detoxification systems To be Published
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3DLW
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![BU of 3dlw by Molmil](/molmil-images/mine/3dlw) | Antichymotrypsin | 分子名称: | Alpha-1-antichymotrypsin | 著者 | Feil, S.C. | 登録日 | 2008-06-29 | 公開日 | 2009-07-07 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Identification and characterization of a misfolded monomeric serpin formed at physiological temperature J.Mol.Biol., 403, 2010
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4GWI
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![BU of 4gwi by Molmil](/molmil-images/mine/4gwi) | |
3SL8
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![BU of 3sl8 by Molmil](/molmil-images/mine/3sl8) | Crystal structure of the catalytic domain of PDE4D2 with compound 10o | 分子名称: | 1,2-ETHANEDIOL, 3-cyclopentyl 6-ethenyl 2-[(thiophen-2-ylacetyl)amino]-4,7-dihydrothieno[2,3-c]pyridine-3,6(5H)-dicarboxylate, DI(HYDROXYETHYL)ETHER, ... | 著者 | Feil, S.F. | 登録日 | 2011-06-24 | 公開日 | 2011-10-26 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Thiophene inhibitors of PDE4: Crystal structures show a second binding mode at the catalytic domain of PDE4D2. Bioorg.Med.Chem.Lett., 21, 2011
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3SL3
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![BU of 3sl3 by Molmil](/molmil-images/mine/3sl3) | Crystal structure of the apo form of the catalytic domain of PDE4D2 | 分子名称: | 1,2-ETHANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, DI(HYDROXYETHYL)ETHER, ... | 著者 | Feil, S.F. | 登録日 | 2011-06-24 | 公開日 | 2011-10-26 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Thiophene inhibitors of PDE4: Crystal structures show a second binding mode at the catalytic domain of PDE4D2. Bioorg.Med.Chem.Lett., 21, 2011
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