3APN
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![BU of 3apn by Molmil](/molmil-images/mine/3apn) | Crystal structure of the human wild-type PAD4 protein | 分子名称: | Protein-arginine deiminase type-4 | 著者 | Horikoshi, N, Tachiwana, H, Saito, K, Osakabe, A, Sato, M, Yamada, M, Akashi, S, Nishimura, Y, Kagawa, W, Kurumizaka, H. | 登録日 | 2010-10-19 | 公開日 | 2011-01-26 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Structural and biochemical analyses of the human PAD4 variant encoded by a functional haplotype gene Acta Crystallogr.,Sect.D, 67, 2011
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3A11
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![BU of 3a11 by Molmil](/molmil-images/mine/3a11) | Crystal structure of ribose-1,5-bisphosphate isomerase from Thermococcus kodakaraensis KOD1 | 分子名称: | DI(HYDROXYETHYL)ETHER, MAGNESIUM ION, Translation initiation factor eIF-2B, ... | 著者 | Nakamura, A, Fujihashi, M, Nishiba, Y, Yoshida, S, Yano, A, Atomi, H, Imanaka, T, Miki, K. | 登録日 | 2009-03-25 | 公開日 | 2010-03-31 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Dynamic, ligand-dependent conformational change triggers reaction of ribose-1,5-bisphosphate isomerase from Thermococcus kodakarensis KOD1 J.Biol.Chem., 287, 2012
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2DTX
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![BU of 2dtx by Molmil](/molmil-images/mine/2dtx) | Structure of Thermoplasma acidophilum aldohexose dehydrogenase (AldT) in complex with D-mannose | 分子名称: | Glucose 1-dehydrogenase related protein, SULFATE ION, beta-D-mannopyranose | 著者 | Yasutake, Y, Nishiya, Y, Tamura, N, Tamura, T. | 登録日 | 2006-07-18 | 公開日 | 2007-03-27 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Structural Insights into Unique Substrate Selectivity of Thermoplasma acidophilumd-Aldohexose Dehydrogenase J.Mol.Biol., 367, 2007
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2DTD
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![BU of 2dtd by Molmil](/molmil-images/mine/2dtd) | Structure of Thermoplasma acidophilum aldohexose dehydrogenase (AldT) in ligand-free form | 分子名称: | Glucose 1-dehydrogenase related protein, SULFATE ION | 著者 | Yasutake, Y, Nishiya, Y, Tamura, N, Tamura, T. | 登録日 | 2006-07-12 | 公開日 | 2007-03-27 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structural Insights into Unique Substrate Selectivity of Thermoplasma acidophilumd-Aldohexose Dehydrogenase J.Mol.Biol., 367, 2007
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2DTE
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![BU of 2dte by Molmil](/molmil-images/mine/2dte) | Structure of Thermoplasma acidophilum aldohexose dehydrogenase (AldT) in complex with NADH | 分子名称: | 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, Glucose 1-dehydrogenase related protein | 著者 | Yasutake, Y, Nishiya, Y, Tamura, N, Tamura, T. | 登録日 | 2006-07-12 | 公開日 | 2007-03-27 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Structural Insights into Unique Substrate Selectivity of Thermoplasma acidophilumd-Aldohexose Dehydrogenase J.Mol.Biol., 367, 2007
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2CZY
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![BU of 2czy by Molmil](/molmil-images/mine/2czy) | Solution structure of the NRSF/REST-mSin3B PAH1 complex | 分子名称: | Paired amphipathic helix protein Sin3b, transcription factor REST (version 3) | 著者 | Nomura, M, Uda-Tochio, H, Murai, K, Mori, N, Nishimura, Y. | 登録日 | 2005-07-20 | 公開日 | 2005-12-20 | 最終更新日 | 2024-05-29 | 実験手法 | SOLUTION NMR | 主引用文献 | The Neural Repressor NRSF/REST Binds the PAH1 Domain of the Sin3 Corepressor by Using its Distinct Short Hydrophobic Helix J.Mol.Biol., 354, 2005
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2DY8
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![BU of 2dy8 by Molmil](/molmil-images/mine/2dy8) | |
2DY7
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1QG7
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![BU of 1qg7 by Molmil](/molmil-images/mine/1qg7) | STROMA CELL-DERIVED FACTOR-1ALPHA (SDF-1ALPHA) | 分子名称: | STROMAL CELL-DERIVED FACTOR 1 ALPHA, SULFATE ION | 著者 | Senda, T, Nandhagopal, N, Sugimoto, K, Mitsui, Y. | 登録日 | 1999-04-21 | 公開日 | 2001-02-28 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Crystal structure of recombinant native SDF-1alpha with additional mutagenesis studies: an attempt at a more comprehensive interpretation of accumulated structure-activity relationship data. J.Interferon Cytokine Res., 20, 2000
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3CLF
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3CLE
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5B7V
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![BU of 5b7v by Molmil](/molmil-images/mine/5b7v) | Human FGFR1 kinase in complex with CH5183284 | 分子名称: | Fibroblast growth factor receptor 1, SULFATE ION, [5-amino-1-(2-methyl-1H-benzimidazol-6-yl)-1H-pyrazol-4-yl](1H-indol-2-yl)methanone | 著者 | Fukami, T.A, Lukacs, C.M, Janson, C. | 登録日 | 2016-06-09 | 公開日 | 2016-06-22 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | The fibroblast growth factor receptor genetic status as a potential predictor of the sensitivity to CH5183284/Debio 1347, a novel selective FGFR inhibitor Mol.Cancer Ther., 13, 2014
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2E5D
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![BU of 2e5d by Molmil](/molmil-images/mine/2e5d) | Crystal structure of Human NMPRTase complexed with nicotinamide | 分子名称: | NICOTINAMIDE, Nicotinamide phosphoribosyltransferase | 著者 | Takahashi, R, Nakamura, S, Kobayashi, Y, Ohkubo, T. | 登録日 | 2006-12-20 | 公開日 | 2007-12-25 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structure and reaction mechanism of human nicotinamide phosphoribosyltransferase J.Biochem., 147, 2010
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2E5B
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2E5C
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![BU of 2e5c by Molmil](/molmil-images/mine/2e5c) | Crystal structure of Human NMPRTase complexed with 5'-phosphoribosyl-1'-pyrophosphate | 分子名称: | 1-O-pyrophosphono-5-O-phosphono-alpha-D-ribofuranose, Nicotinamide phosphoribosyltransferase | 著者 | Takahashi, R, Nakamura, S, Kobayashi, Y, Ohkubo, T. | 登録日 | 2006-12-20 | 公開日 | 2007-12-25 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structure and reaction mechanism of human nicotinamide phosphoribosyltransferase J.Biochem., 147, 2010
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7YV1
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![BU of 7yv1 by Molmil](/molmil-images/mine/7yv1) | Human K-Ras G12D (GDP-bound) in complex with cyclic peptide inhibitor LUNA18 and KA30L Fab | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, Isoform 2B of GTPase KRas, KA30L Fab H-chain, ... | 著者 | Irie, M, Fukami, T.A, Matsuo, A, Saka, K, Nishimura, M, Saito, H, Torizawa, T, Tanada, M, Ohta, A. | 登録日 | 2022-08-18 | 公開日 | 2023-07-26 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.454 Å) | 主引用文献 | Validation of a New Methodology to Create Oral Drugs beyond the Rule of 5 for Intracellular Tough Targets. J.Am.Chem.Soc., 145, 2023
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7YUZ
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![BU of 7yuz by Molmil](/molmil-images/mine/7yuz) | Human K-Ras G12D (GDP-bound) in complex with cyclic peptide inhibitor AP8784 | 分子名称: | AP8784, GUANOSINE-5'-DIPHOSPHATE, IODIDE ION, ... | 著者 | Irie, M, Fukami, T.A, Tanada, M, Ohta, A, Torizawa, T. | 登録日 | 2022-08-18 | 公開日 | 2023-07-26 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.878 Å) | 主引用文献 | Validation of a New Methodology to Create Oral Drugs beyond the Rule of 5 for Intracellular Tough Targets. J.Am.Chem.Soc., 145, 2023
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8W85
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![BU of 8w85 by Molmil](/molmil-images/mine/8w85) | HLA-DQ2.5-gamma2 gliadin peptide in complex with DQN0385AE01 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, DQN0385AE01 Fab heavy chain, DQN0385AE01 Fab light chain, ... | 著者 | Irie, M, Tsushima, T, Teranishi-Ikawa, Y, Takahashi, N, Ishii, S, Okura, Y, Fukami, T.A, Torizawa, T. | 登録日 | 2023-08-31 | 公開日 | 2023-11-08 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.769 Å) | 主引用文献 | Characterizations of a neutralizing antibody broadly reactive to multiple gluten peptide:HLA-DQ2.5 complexes in the context of celiac disease. Nat Commun, 14, 2023
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8W86
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![BU of 8w86 by Molmil](/molmil-images/mine/8w86) | HLA-DQ2.5-B/C hordein peptide in complex with DQN0385AE02 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, DQN0385AE02 Fab heavy chain, DQN0385AE02 Fab light chain, ... | 著者 | Irie, M, Tsushima, T, Teranishi-Ikawa, Y, Takahashi, N, Ishii, S, Okura, Y, Fukami, T.A, Torizawa, T. | 登録日 | 2023-08-31 | 公開日 | 2023-11-08 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.236 Å) | 主引用文献 | Characterizations of a neutralizing antibody broadly reactive to multiple gluten peptide:HLA-DQ2.5 complexes in the context of celiac disease. Nat Commun, 14, 2023
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8W84
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![BU of 8w84 by Molmil](/molmil-images/mine/8w84) | HLA-DQ2.5-alpha2 gliadin peptide in complex with DQN0344AE02 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, DQN0344AE02 Fab heavy chain, DQN0344AE02 Fab light chain, ... | 著者 | Irie, M, Tsushima, T, Teranishi-Ikawa, Y, Takahashi, N, Ishii, S, Okura, Y, Fukami, T.A, Torizawa, T. | 登録日 | 2023-08-31 | 公開日 | 2023-11-08 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.105 Å) | 主引用文献 | Characterizations of a neutralizing antibody broadly reactive to multiple gluten peptide:HLA-DQ2.5 complexes in the context of celiac disease. Nat Commun, 14, 2023
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8W83
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![BU of 8w83 by Molmil](/molmil-images/mine/8w83) | HLA-DQ2.5-alpha1 gliadin peptide in complex with DQN0344AE02 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, DQN0344AE02 Fab heavy chain, DQN0344AE02 Fab light chain, ... | 著者 | Irie, M, Tsushima, T, Teranishi-Ikawa, Y, Takahashi, N, Ishii, S, Okura, Y, Fukami, T.A, Torizawa, T. | 登録日 | 2023-08-31 | 公開日 | 2023-11-08 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.818 Å) | 主引用文献 | Characterizations of a neutralizing antibody broadly reactive to multiple gluten peptide:HLA-DQ2.5 complexes in the context of celiac disease. Nat Commun, 14, 2023
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6DL7
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![BU of 6dl7 by Molmil](/molmil-images/mine/6dl7) | Human mitochondrial ClpP in complex with ONC201 (TIC10) | 分子名称: | 7-benzyl-4-[(2-methylphenyl)methyl]-6,7,8,9-tetrahydroimidazo[1,2-a]pyrido[3,4-e]pyrimidin-5(4H)-one, ATP-dependent Clp protease proteolytic subunit, mitochondrial | 著者 | Halgas, O, Zarabi, S.F, Schimmer, A, Pai, E.F. | 登録日 | 2018-05-31 | 公開日 | 2019-05-08 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Mitochondrial ClpP-Mediated Proteolysis Induces Selective Cancer Cell Lethality. Cancer Cell, 35, 2019
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3IWR
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![BU of 3iwr by Molmil](/molmil-images/mine/3iwr) | Crystal structure of class I chitinase from Oryza sativa L. japonica | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Chitinase | 著者 | Kezuka, Y, Watanabe, T, Nonaka, T. | 登録日 | 2009-09-03 | 公開日 | 2010-04-21 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.57 Å) | 主引用文献 | Structure of full-length class I chitinase from rice revealed by X-ray crystallography and small-angle X-ray scattering. Proteins, 78, 2010
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8JS5
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![BU of 8js5 by Molmil](/molmil-images/mine/8js5) | Dimeric PAS domains of oxygen sensor FixL with ferric unliganded heme | 分子名称: | GLYCEROL, PROTOPORPHYRIN IX CONTAINING FE, Sensor protein FixL | 著者 | Kamaya, M, Koteishi, H, Sawai, H, Sugimoto, H, Shiro, Y. | 登録日 | 2023-06-19 | 公開日 | 2024-06-26 | 実験手法 | X-RAY DIFFRACTION (2.95 Å) | 主引用文献 | Dimeric PAS domains of oxygen sensor FixL in complex with imidazole-bound heme. To be published
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8JS7
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![BU of 8js7 by Molmil](/molmil-images/mine/8js7) | Dimeric PAS domains of oxygen sensor FixL in complex with imidazole-bound heme | 分子名称: | GLYCEROL, IMIDAZOLE, PROTOPORPHYRIN IX CONTAINING FE, ... | 著者 | Kamaya, M, Koteishi, H, Sawai, H, Sugimoto, H, Shiro, Y. | 登録日 | 2023-06-19 | 公開日 | 2024-06-26 | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | 主引用文献 | Dimeric PAS domains of oxygen sensor FixL in complex with imidazole-bound heme. To be published
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