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8G4H
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BU of 8g4h by Molmil
KRAS G13C complex with GDP imaged on a cryo-EM imaging scaffold
分子名称: GTPase KRas, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
著者Castells-Graells, R, Sawaya, M.R, Yeates, T.O.
登録日2023-02-09
公開日2023-08-09
最終更新日2023-09-27
実験手法ELECTRON MICROSCOPY (2.87 Å)
主引用文献Cryo-EM structure determination of small therapeutic protein targets at 3 angstrom -resolution using a rigid imaging scaffold.
Proc.Natl.Acad.Sci.USA, 120, 2023
8G4E
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BU of 8g4e by Molmil
Green Fluorescence Protein imaged on a cryo-EM imaging scaffold
分子名称: RCG-10 - Cryo-EM imaging scaffold subunit B fused to DARPin, Superfolder Green Fluorescent Protein
著者Castells-Graells, R, Sawaya, M.R, Yeates, T.O.
登録日2023-02-09
公開日2023-08-09
最終更新日2023-11-15
実験手法ELECTRON MICROSCOPY (2.98 Å)
主引用文献Cryo-EM structure determination of small therapeutic protein targets at 3 angstrom -resolution using a rigid imaging scaffold.
Proc.Natl.Acad.Sci.USA, 120, 2023
8G42
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BU of 8g42 by Molmil
KRAS G12C complex with GDP imaged on a cryo-EM imaging scaffold
分子名称: GTPase KRas, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
著者Castells-Graells, R, Sawaya, M.R, Yeates, T.O.
登録日2023-02-08
公開日2023-08-09
最終更新日2023-09-27
実験手法ELECTRON MICROSCOPY (3.02 Å)
主引用文献Cryo-EM structure determination of small therapeutic protein targets at 3 angstrom -resolution using a rigid imaging scaffold.
Proc.Natl.Acad.Sci.USA, 120, 2023
8G4F
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BU of 8g4f by Molmil
KRAS G12V complex with GDP imaged on a cryo-EM imaging scaffold
分子名称: GTPase KRas, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
著者Castells-Graells, R, Sawaya, M.R, Yeates, T.O.
登録日2023-02-09
公開日2023-08-09
最終更新日2023-09-27
実験手法ELECTRON MICROSCOPY (2.91 Å)
主引用文献Cryo-EM structure determination of small therapeutic protein targets at 3 angstrom -resolution using a rigid imaging scaffold.
Proc.Natl.Acad.Sci.USA, 120, 2023
6ANV
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BU of 6anv by Molmil
Crystal structure of anti-CRISPR protein AcrF1
分子名称: 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, DI(HYDROXYETHYL)ETHER, ...
著者Yang, H, Patel, D.J.
登録日2017-08-14
公開日2017-10-25
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.265 Å)
主引用文献Cryo-EM Structures Reveal Mechanism and Inhibition of DNA Targeting by a CRISPR-Cas Surveillance Complex.
Cell, 171, 2017
6ANW
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BU of 6anw by Molmil
Crystal structure of anti-CRISPR protein AcrF10
分子名称: anti-CRISPR protein AcrF10
著者Yang, H, Patel, D.J.
登録日2017-08-14
公開日2017-10-25
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.486 Å)
主引用文献Cryo-EM Structures Reveal Mechanism and Inhibition of DNA Targeting by a CRISPR-Cas Surveillance Complex.
Cell, 171, 2017
4KHX
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BU of 4khx by Molmil
Crystal structure of gp41 helix complexed with antibody 8062
分子名称: 8062 heavy chain, 8062 light chain, gp41 helix
著者Li, M, Gustchina, A, Wlodawer, A.
登録日2013-05-01
公開日2014-03-12
最終更新日2017-11-15
実験手法X-RAY DIFFRACTION (2.921 Å)
主引用文献Complexes of neutralizing and non-neutralizing affinity matured Fabs with a mimetic of the internal trimeric coiled-coil of HIV-1 gp41.
Plos One, 8, 2013
4YE6
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BU of 4ye6 by Molmil
The crystal structure of the intact human GlnRS
分子名称: Glutamine--tRNA ligase
著者Ognjenovic, J, Wu, J, Ling, J, Simonovic, M.
登録日2015-02-23
公開日2016-02-17
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献The crystal structure of human GlnRS provides basis for the development of neurological disorders.
Nucleic Acids Res., 44, 2016
4YE9
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BU of 4ye9 by Molmil
The crystal structure of the G45V mutant of human GlnRS
分子名称: Glutamine--tRNA ligase
著者Ognjenovic, J, Wu, J, Ling, J, Simonovic, M.
登録日2015-02-23
公開日2016-02-17
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献The crystal structure of human GlnRS provides basis for the development of neurological disorders.
Nucleic Acids Res., 44, 2016
4YE8
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BU of 4ye8 by Molmil
The crystal structure of the Y57H mutant of human GlnRS
分子名称: Glutamine--tRNA ligase
著者Ognjenovic, J, Wu, J, Ling, J, Simonovic, M.
登録日2015-02-23
公開日2016-02-17
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献The crystal structure of human GlnRS provides basis for the development of neurological disorders.
Nucleic Acids Res., 44, 2016
4KHT
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BU of 4kht by Molmil
Triple helix bundle of GP41 complexed with fab 8066
分子名称: 8066 heavy chain, 8066 light chain, Gp41 helix
著者Li, M, Gustchina, A, Wlodawer, A.
登録日2013-05-01
公開日2014-03-12
最終更新日2017-11-15
実験手法X-RAY DIFFRACTION (2.817 Å)
主引用文献Complexes of neutralizing and non-neutralizing affinity matured Fabs with a mimetic of the internal trimeric coiled-coil of HIV-1 gp41.
Plos One, 8, 2013
4ZDP
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BU of 4zdp by Molmil
The crystal structure of Y334C mutant of human SepSecS in complex with selenocysteine tRNA (tRNASec)
分子名称: (5-HYDROXY-4,6-DIMETHYLPYRIDIN-3-YL)METHYL DIHYDROGEN PHOSPHATE, O-phosphoseryl-tRNA(Sec) selenium transferase, PHOSPHATE ION, ...
著者French, R.L, Simonovic, M.
登録日2015-04-17
公開日2016-04-20
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.703 Å)
主引用文献Structural basis for early-onset neurological disorders caused by mutations in human selenocysteine synthase.
Sci Rep, 6, 2016
3J70
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BU of 3j70 by Molmil
Model of gp120, including variable regions, in complex with CD4 and 17b
分子名称: Envelope glycoprotein gp120, T-cell surface glycoprotein CD4, envelope glycoprotein gp41, ...
著者Rasheed, M, Bettadapura, R, Bajaj, C.
登録日2014-04-22
公開日2015-08-26
実験手法ELECTRON MICROSCOPY (20 Å)
主引用文献Computational Refinement and Validation Protocol for Proteins with Large Variable Regions Applied to Model HIV Env Spike in CD4 and 17b Bound State.
Structure, 23, 2015
4WXI
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BU of 4wxi by Molmil
FACTOR XIA IN COMPLEX WITH THE INHIBITOR trans-N-{(1S)-1-[4-(3-amino-2H-indazol-6-yl)pyridin-2-yl]-2-phenylethyl}-4-(aminomethyl)cyclohexanecarboxamide
分子名称: 1,2-ETHANEDIOL, COAGULATION FACTOR XI, LIGHT CHAIN, ...
著者Wei, A.
登録日2014-11-13
公開日2015-01-28
最終更新日2018-08-29
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Pyridine and pyridinone-based factor XIa inhibitors.
Bioorg.Med.Chem.Lett., 25, 2015

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件を2024-07-31に公開中

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