8DDI
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8DDM
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6L8Q
| Complex structure of bat CD26 and MERS-RBD | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Dipeptidyl peptidase 4, ... | 著者 | Yuan, Y. | 登録日 | 2019-11-07 | 公開日 | 2019-12-04 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | Molecular Basis of Binding between Middle East Respiratory Syndrome Coronavirus and CD26 from Seven Bat Species. J.Virol., 94, 2020
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7JRN
| Crystal structure of the wild type SARS-CoV-2 papain-like protease (PLPro) with inhibitor GRL0617 | 分子名称: | 5-amino-2-methyl-N-[(1R)-1-naphthalen-1-ylethyl]benzamide, Non-structural protein 3, SULFATE ION, ... | 著者 | Sacco, M, Ma, C, Wang, J, Chen, Y. | 登録日 | 2020-08-12 | 公開日 | 2020-08-26 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.48 Å) | 主引用文献 | Discovery of SARS-CoV-2 Papain-like Protease Inhibitors through a Combination of High-Throughput Screening and a FlipGFP-Based Reporter Assay. Acs Cent.Sci., 7, 2021
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3QWX
| CED-2 1-174 | 分子名称: | Cell death abnormality protein 2, SULFATE ION | 著者 | Kang, Y, Sun, J, Liu, Y. | 登録日 | 2011-02-28 | 公開日 | 2011-06-08 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.01 Å) | 主引用文献 | Crystal structure of the cell corpse engulfment protein CED-2 in Caenorhabditis elegans. Biochem.Biophys.Res.Commun., 410, 2011
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3IGB
| Bace-1 with Compound 3 | 分子名称: | 8,8-diphenyl-2,3,4,8-tetrahydroimidazo[1,5-a]pyrimidin-6-amine, Beta-secretase 1 | 著者 | Olland, A.M. | 登録日 | 2009-07-27 | 公開日 | 2009-11-03 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.238 Å) | 主引用文献 | Aminoimidazoles as potent and selective human beta-secretase (BACE1) inhibitors J.Med.Chem., 52, 2009
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3IN4
| Bace1 with Compound 38 | 分子名称: | (5S)-2-amino-5-(2,6-diethylpyridin-4-yl)-3-methyl-5-(3-pyrimidin-5-ylphenyl)-3,5-dihydro-4H-imidazol-4-one, Beta-secretase 1 | 著者 | Olland, A.M. | 登録日 | 2009-08-11 | 公開日 | 2010-01-19 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Di-substituted pyridinyl aminohydantoins as potent and highly selective human beta-secretase (BACE1) inhibitors. Bioorg.Med.Chem., 18, 2010
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3IN3
| Bace1 with Compound 30 | 分子名称: | (5S)-2-amino-3-methyl-5-pyridin-4-yl-5-(3-pyridin-3-ylphenyl)-3,5-dihydro-4H-imidazol-4-one, Beta-secretase 1 | 著者 | Olland, A.M. | 登録日 | 2009-08-11 | 公開日 | 2010-01-19 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Di-substituted pyridinyl aminohydantoins as potent and highly selective human beta-secretase (BACE1) inhibitors. Bioorg.Med.Chem., 18, 2010
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6KUZ
| E.coli beta-galactosidase (E537Q) in complex with fluorescent probe KSL01 | 分子名称: | 3-(1,3-benzothiazol-2-yl)-2-[[4-[(2~{S},3~{R},4~{S},5~{R},6~{R})-6-(hydroxymethyl)-3,4,5-tris(oxidanyl)oxan-2-yl]oxyphenyl]methoxy]-5-methyl-benzaldehyde, Beta-galactosidase, DIMETHYL SULFOXIDE, ... | 著者 | Chen, X, Hu, Y.L, Li, X.K, Guo, Y, Li, J. | 登録日 | 2019-09-03 | 公開日 | 2020-07-08 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.83 Å) | 主引用文献 | First-generation species-selective chemical probes for fluorescence imaging of human senescence-associated beta-galactosidase. Chem Sci, 11, 2020
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7M71
| SARS-CoV-2 Spike:5A6 Fab complex I focused refinement | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody 5A6 Fab heavy chain, Antibody 5A6 Fab light chain, ... | 著者 | Asarnow, D, Cheng, Y. | 登録日 | 2021-03-26 | 公開日 | 2021-05-26 | 最終更新日 | 2021-06-23 | 実験手法 | ELECTRON MICROSCOPY (2.66 Å) | 主引用文献 | Structural insight into SARS-CoV-2 neutralizing antibodies and modulation of syncytia. Cell, 184, 2021
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7M7B
| SARS-CoV-2 Spike:Fab 3D11 complex focused refinement | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody Fab 3D11 heavy chain, Antibody Fab 3D11 light chain, ... | 著者 | Asarnow, D, Cheng, Y. | 登録日 | 2021-03-27 | 公開日 | 2021-05-26 | 最終更新日 | 2021-06-23 | 実験手法 | ELECTRON MICROSCOPY (2.95 Å) | 主引用文献 | Structural insight into SARS-CoV-2 neutralizing antibodies and modulation of syncytia. Cell, 184, 2021
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3LHG
| Bace1 in complex with the aminohydantoin Compound 4g | 分子名称: | (5S)-2-amino-5-(2',5'-difluorobiphenyl-3-yl)-3-methyl-5-pyridin-4-yl-3,5-dihydro-4H-imidazol-4-one, Beta-secretase 1 | 著者 | Olland, A.M. | 登録日 | 2010-01-22 | 公開日 | 2010-04-21 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Pyridinyl aminohydantoins as small molecule BACE1 inhibitors. Bioorg.Med.Chem.Lett., 20, 2010
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7M8E
| E.coli RNAP-RapA elongation complex | 分子名称: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | 著者 | Shi, W, Liu, B. | 登録日 | 2021-03-29 | 公開日 | 2021-08-18 | 最終更新日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Structural basis for activation of Swi2/Snf2 ATPase RapA by RNA polymerase. Nucleic Acids Res., 49, 2021
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7JQC
| SARS-CoV-2 Nsp1, CrPV IRES and rabbit 40S ribosome complex | 分子名称: | 40S ribosomal protein S21, 40S ribosomal protein S24, 40S ribosomal protein S26, ... | 著者 | Yuan, S, Xiong, Y. | 登録日 | 2020-08-10 | 公開日 | 2020-12-02 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Nonstructural Protein 1 of SARS-CoV-2 Is a Potent Pathogenicity Factor Redirecting Host Protein Synthesis Machinery toward Viral RNA. Mol.Cell, 80, 2020
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7JQB
| SARS-CoV-2 Nsp1 and rabbit 40S ribosome complex | 分子名称: | 40S ribosomal protein S21, 40S ribosomal protein S24, 40S ribosomal protein S26, ... | 著者 | Yuan, S, Xiong, Y. | 登録日 | 2020-08-10 | 公開日 | 2020-12-02 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | 主引用文献 | Nonstructural Protein 1 of SARS-CoV-2 Is a Potent Pathogenicity Factor Redirecting Host Protein Synthesis Machinery toward Viral RNA. Mol.Cell, 80, 2020
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7LGS
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7KQB
| SARS-CoV-2 spike glycoprotein:Fab 5A6 complex I | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Fab 5A6 heavy chain, Fab 5A6 light chain, ... | 著者 | Asarnow, D, Charles, C, Cheng, Y. | 登録日 | 2020-11-14 | 公開日 | 2021-05-26 | 最終更新日 | 2021-06-23 | 実験手法 | ELECTRON MICROSCOPY (2.42 Å) | 主引用文献 | Structural insight into SARS-CoV-2 neutralizing antibodies and modulation of syncytia. Cell, 184, 2021
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7KQE
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2FEK
| Structure of a protein tyrosine phosphatase | 分子名称: | Low molecular weight protein-tyrosine-phosphatase wzb | 著者 | Lescop, E, Jin, C. | 登録日 | 2005-12-16 | 公開日 | 2006-05-09 | 最終更新日 | 2024-05-29 | 実験手法 | SOLUTION NMR | 主引用文献 | The solution structure of Escherichia coli Wzb reveals a novel substrate recognition mechanism of prokaryotic low molecular weight protein-tyrosine phosphatases J.Biol.Chem., 281, 2006
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5KUC
| Crystal structure of trypsin activated Cry6Aa | 分子名称: | Pesticidal crystal protein Cry6Aa | 著者 | Kelker, M.S, Xu, X, Lee, M, Chan, M, Hung, S, Dementiev, K, Hey, T, Chikwana, V.M, Narva, K.E. | 登録日 | 2016-07-13 | 公開日 | 2016-08-03 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | The pesticidal Cry6Aa toxin from Bacillus thuringiensis is structurally similar to HlyE-family alpha pore-forming toxins. Bmc Biol., 14, 2016
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5KUD
| Crystal structure of full length Cry6Aa | 分子名称: | Pesticidal crystal protein Cry6Aa | 著者 | Kelker, M.S, Xu, X, Lee, M, Chan, M, Hung, S, Dementiev, K, Chikwana, V.M, Hey, T, Narva, K. | 登録日 | 2016-07-13 | 公開日 | 2016-08-03 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | The pesticidal Cry6Aa toxin from Bacillus thuringiensis is structurally similar to HlyE-family alpha pore-forming toxins. Bmc Biol., 14, 2016
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5ITI
| A cynobacterial PP2C (tPphA) structure | 分子名称: | CALCIUM ION, Protein serin-threonin phosphatase | 著者 | Su, J.Y. | 登録日 | 2016-03-16 | 公開日 | 2016-05-04 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Structural and Biochemical Characterization of a Cyanobacterial PP2C Phosphatase Reveals Insights into Catalytic Mechanism and Substrate Recognition Catalysts, 6, 2016
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5D2U
| Crystal structure of tPphA Variant - H39A | 分子名称: | CALCIUM ION, Protein serin-threonin phosphatase | 著者 | Su, J. | 登録日 | 2015-08-06 | 公開日 | 2016-05-04 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Structural and Biochemical Characterization of a Cyanobacterial PP2C Phosphatase Reveals Insights into Catalytic Mechanism and Substrate Recognition Catalysts, 2016
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6OCF
| The crystal structure of VASH1-SVBP complex | 分子名称: | CHLORIDE ION, GLYCEROL, Small vasohibin-binding protein, ... | 著者 | Li, F, Luo, X, Yu, H. | 登録日 | 2019-03-23 | 公開日 | 2019-06-26 | 最終更新日 | 2019-12-18 | 実験手法 | X-RAY DIFFRACTION (2.102 Å) | 主引用文献 | Structural basis of tubulin detyrosination by vasohibins. Nat.Struct.Mol.Biol., 26, 2019
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2HVJ
| Crystal structure of KcsA-Fab-TBA complex in low K+ | 分子名称: | (2S)-3-HYDROXY-2-(NONANOYLOXY)PROPYL LAURATE, NONAN-1-OL, POTASSIUM ION, ... | 著者 | Zhou, Y. | 登録日 | 2006-07-28 | 公開日 | 2007-02-20 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | 主引用文献 | Crystallographic Study of the Tetrabutylammonium Block to the KcsA K(+) Channel. J.Mol.Biol., 366, 2007
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