6NMC
 
 | | CryoEM structure of the LbCas12a-crRNA-2xAcrVA1 complex | | 分子名称: | AcrVA1, Cpf1, MAGNESIUM ION, ... | | 著者 | Chang, L, Li, Z, Zhang, H. | | 登録日 | 2019-01-10 | | 公開日 | 2019-06-12 | | 最終更新日 | 2024-03-20 | | 実験手法 | ELECTRON MICROSCOPY (4.24 Å) | | 主引用文献 | Structural Basis for the Inhibition of CRISPR-Cas12a by Anti-CRISPR Proteins.
Cell Host Microbe, 25, 2019
|
|
6NMD
 | | cryo-EM Structure of the LbCas12a-crRNA-AcrVA1 complex | | 分子名称: | AcrVA1, Cpf1, MAGNESIUM ION, ... | | 著者 | Chang, L, Li, Z, Zhang, H. | | 登録日 | 2019-01-10 | | 公開日 | 2019-06-12 | | 最終更新日 | 2024-03-20 | | 実験手法 | ELECTRON MICROSCOPY (3.49 Å) | | 主引用文献 | Structural Basis for the Inhibition of CRISPR-Cas12a by Anti-CRISPR Proteins.
Cell Host Microbe, 25, 2019
|
|
8Z0L
 | | Cryo-EM structure of Cas8-HNH system at partial R-loop state | | 分子名称: | DNA (32-MER), DNA (5'-D(P*GP*TP*GP*CP*GP*GP*A)-3'), HNH endonuclease, ... | | 著者 | Zhang, H, Zhu, H, Li, X, Liu, Y. | | 登録日 | 2024-04-09 | | 公開日 | 2024-10-02 | | 最終更新日 | 2024-10-09 | | 実験手法 | ELECTRON MICROSCOPY (2.57 Å) | | 主引用文献 | Structural basis for the type I-F Cas8-HNH system.
Embo J., 2024
|
|
8ZDY
 | |
8Z0K
 | | Cryo-EM structure of Cas8-HNH system at full R-loop state | | 分子名称: | DNA (37-MER), DNA (5'-D(P*GP*TP*GP*CP*GP*GP*A)-3'), HNH endonuclease, ... | | 著者 | Zhang, H, Zhu, H, Li, X, Liu, Y. | | 登録日 | 2024-04-09 | | 公開日 | 2024-10-02 | | 最終更新日 | 2024-10-09 | | 実験手法 | ELECTRON MICROSCOPY (2.51 Å) | | 主引用文献 | Structural basis for the type I-F Cas8-HNH system.
Embo J., 2024
|
|
8ZNR
 | | Cryo-EM structure of Cas8-HNH system at ssDNA-bound state | | 分子名称: | DNA (35-MER), RNA (56-MER), protein structure | | 著者 | Zhang, H, Zhu, H, Li, X, Liu, Y. | | 登録日 | 2024-05-28 | | 公開日 | 2024-10-02 | | 最終更新日 | 2024-10-09 | | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | | 主引用文献 | Structural basis for the type I-F Cas8-HNH system.
Embo J., 2024
|
|
8Z9C
 | | Cryo-EM structure of NTR-bound type VII CRISPR-Cas complex at substrate-engaged state I | | 分子名称: | Protein structure, RNA (41-MER), RNA (48-MER), ... | | 著者 | Zhang, H, Deng, Z, Li, X. | | 登録日 | 2024-04-23 | | 公開日 | 2024-08-21 | | 最終更新日 | 2024-09-25 | | 実験手法 | ELECTRON MICROSCOPY (3.01 Å) | | 主引用文献 | Structural basis for the activity of the type VII CRISPR-Cas system.
Nature, 633, 2024
|
|
8Z4L
 | | Cryo-EM structure of CTR-bound type VII CRISPR-Cas complex at substrate-engaged state I | | 分子名称: | RNA (40-MER), RNA (49-MER), ZINC ION, ... | | 著者 | Zhang, H, Deng, Z, Li, X. | | 登録日 | 2024-04-17 | | 公開日 | 2024-08-21 | | 最終更新日 | 2024-09-25 | | 実験手法 | ELECTRON MICROSCOPY (2.85 Å) | | 主引用文献 | Structural basis for the activity of the type VII CRISPR-Cas system.
Nature, 633, 2024
|
|
8Z4J
 | | Cryo-EM structure of CTR-bound type VII CRISPR-Cas complex at substrate-engaged state II | | 分子名称: | Protein structure, RNA (34-MER), RNA (38-MER), ... | | 著者 | Zhang, H, Deng, Z, Li, X. | | 登録日 | 2024-04-17 | | 公開日 | 2024-08-21 | | 最終更新日 | 2024-09-25 | | 実験手法 | ELECTRON MICROSCOPY (2.97 Å) | | 主引用文献 | Structural basis for the activity of the type VII CRISPR-Cas system.
Nature, 633, 2024
|
|
8Z9E
 | | Cryo-EM structure of NTR-bound type VII CRISPR-Cas complex at substrate-engaged state II | | 分子名称: | Protein structure, RNA (34-MER), RNA (39-MER), ... | | 著者 | Zhang, H, Deng, Z, Li, X. | | 登録日 | 2024-04-23 | | 公開日 | 2024-08-21 | | 最終更新日 | 2024-09-25 | | 実験手法 | ELECTRON MICROSCOPY (3.13 Å) | | 主引用文献 | Structural basis for the activity of the type VII CRISPR-Cas system.
Nature, 633, 2024
|
|
8YHE
 | | Cryo-EM structure of CTR-bound type VII CRISPR-Cas complex at post-state II | | 分子名称: | RNA (29-MER), RNA (46-MER), ZINC ION, ... | | 著者 | Zhang, H, Deng, Z, Li, X. | | 登録日 | 2024-02-28 | | 公開日 | 2024-08-21 | | 最終更新日 | 2024-09-25 | | 実験手法 | ELECTRON MICROSCOPY (3.07 Å) | | 主引用文献 | Structural basis for the activity of the type VII CRISPR-Cas system.
Nature, 633, 2024
|
|
8Z99
 | | Cryo-EM structure of NTR-bound type VII CRISPR-Cas complex at substrate-engaged state +I | | 分子名称: | RNA (49-MER), RNA (54-MER), ZINC ION, ... | | 著者 | Zhang, H, Deng, Z, Li, X. | | 登録日 | 2024-04-22 | | 公開日 | 2024-08-21 | | 最終更新日 | 2024-10-16 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Structural basis for the activity of the type VII CRISPR-Cas system.
Nature, 633, 2024
|
|
8YHD
 | | Cryo-EM structure of CTR-bound type VII CRISPR-Cas complex at post-state I | | 分子名称: | RNA (35-MER), RNA (53-MER), ZINC ION, ... | | 著者 | Zhang, H, Deng, Z, Li, X. | | 登録日 | 2024-02-28 | | 公開日 | 2024-08-21 | | 最終更新日 | 2024-09-25 | | 実験手法 | ELECTRON MICROSCOPY (2.93 Å) | | 主引用文献 | Structural basis for the activity of the type VII CRISPR-Cas system.
Nature, 633, 2024
|
|
5XRS
 | |
5XOM
 | | Hydra Fam20 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Glycosaminoglycan xylosylkinase | | 著者 | Xiao, J, Zhang, H. | | 登録日 | 2017-05-29 | | 公開日 | 2018-04-11 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Structure and evolution of the Fam20 kinases
Nat Commun, 9, 2018
|
|
3UAS
 | | Cytochrome P450 2B4 covalently bound to the mechanism-based inactivator 9-ethynylphenanthrene | | 分子名称: | 5-CYCLOHEXYL-1-PENTYL-BETA-D-MALTOSIDE, Cytochrome P450 2B4, PROTOPORPHYRIN IX CONTAINING FE, ... | | 著者 | Gay, S.C, Zhang, H, Shah, M.B, Stout, C.D, Halpert, J.R, Hollenberg, P.F. | | 登録日 | 2011-10-21 | | 公開日 | 2013-01-09 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.939 Å) | | 主引用文献 | Potent Mechanism-Based Inactivation of Cytochrome P450 2B4 by 9-Ethynylphenanthrene: Implications for Allosteric Modulation of Cytochrome P450 Catalysis.
Biochemistry, 52, 2013
|
|
5XRT
 | | Crystal structure of A/Minnesota/11/2010 (H3N2) influenza virus hemagglutinin | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Zhang, H, Wilson, I.A. | | 登録日 | 2017-06-09 | | 公開日 | 2018-07-25 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (3.15 Å) | | 主引用文献 | A multifunctional human monoclonal neutralizing antibody that targets a unique conserved epitope on influenza HA.
Nat Commun, 9, 2018
|
|
5XRQ
 | |
3ROK
 | |
5F1K
 | |
5F1O
 | |
3ROQ
 | | Crystal structure of human CD38 in complex with compound CZ-46 | | 分子名称: | (2R,3R,4S,5S)-4-fluoro-3,5-dihydroxytetrahydrofuran-2-yl 2-phenylethyl hydrogen (S)-phosphate, ADP-ribosyl cyclase 1 | | 著者 | Zhang, H, Lee, H.C, Hao, Q. | | 登録日 | 2011-04-26 | | 公開日 | 2011-12-21 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Catalysis-based inhibitors of the calcium signaling function of CD38.
Biochemistry, 51, 2012
|
|
3ROM
 | |
3ROP
 | |
6W5C
 | | Cryo-EM structure of Cas12i(E894A)-crRNA-dsDNA complex | | 分子名称: | Cas12i, NTS, Substrate, ... | | 著者 | Chang, L, Li, Z, Zhang, H. | | 登録日 | 2020-03-13 | | 公開日 | 2020-09-16 | | 最終更新日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | | 主引用文献 | Mechanisms for target recognition and cleavage by the Cas12i RNA-guided endonuclease.
Nat.Struct.Mol.Biol., 27, 2020
|
|
