6DFR
 
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1LT4
 | | HEAT-LABILE ENTEROTOXIN MUTANT S63K | | 分子名称: | HEAT-LABILE ENTEROTOXIN, beta-D-galactopyranose-(1-4)-beta-D-glucopyranose | | 著者 | Van Den Akker, F, Hol, W.G.J. | | 登録日 | 1997-04-14 | | 公開日 | 1997-06-16 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Crystal structure of a non-toxic mutant of heat-labile enterotoxin, which is a potent mucosal adjuvant.
Protein Sci., 6, 1997
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2A5F
 | | Cholera toxin A1 subunit bound to its substrate, NAD+, and its human protein activator, ARF6 | | 分子名称: | ADP-ribosylation factor 6, Cholera enterotoxin, A chain, ... | | 著者 | O'Neal, C.J, Jobling, M.G, Holmes, R.K, Hol, W.G.J. | | 登録日 | 2005-06-30 | | 公開日 | 2005-08-16 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.02 Å) | | 主引用文献 | Structural basis for the activation of cholera toxin by human ARF6-GTP.
Science, 309, 2005
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1YF9
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2A5D
 | | Structural basis for the activation of cholera toxin by human ARF6-GTP | | 分子名称: | ADP-ribosylation factor 6, Cholera enterotoxin, A chain, ... | | 著者 | O'Neal, C.J, Jobling, M.G, Holmes, R.K, Hol, W.G.J. | | 登録日 | 2005-06-30 | | 公開日 | 2005-08-16 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Structural basis for the activation of cholera toxin by human ARF6-GTP.
Science, 309, 2005
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2A5G
 | | Cholera toxin A1 subunit bound to ARF6(Q67L) | | 分子名称: | ADP-ribosylation factor 6, Cholera enterotoxin, A chain, ... | | 著者 | O'Neal, C.J, Jobling, M.G, Holmes, R.K, Hol, W.G.J. | | 登録日 | 2005-06-30 | | 公開日 | 2005-08-16 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.66 Å) | | 主引用文献 | Structural basis for the activation of cholera toxin by human ARF6-GTP.
Science, 309, 2005
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1TEC
 | | CRYSTALLOGRAPHIC REFINEMENT BY INCORPORATION OF MOLECULAR DYNAMICS. THE THERMOSTABLE SERINE PROTEASE THERMITASE COMPLEXED WITH EGLIN-C | | 分子名称: | CALCIUM ION, EGLIN C, SODIUM ION, ... | | 著者 | Gros, P, Dijkstra, B.W, Hol, W.G.J. | | 登録日 | 1989-05-24 | | 公開日 | 1989-10-15 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Crystallographic refinement by incorporation of molecular dynamics: thermostable serine protease thermitase complexed with eglin c.
Acta Crystallogr.,Sect.B, 45, 1989
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1TQX
 | | Crystal Structure of Pfal009167 A Putative D-Ribulose 5-Phosphate 3-Epimerase from P.falciparum | | 分子名称: | D-ribulose-5-phosphate 3-epimerase, putative, SULFATE ION, ... | | 著者 | Caruthers, J, Bosch, J, Hol, W.G.J, Structural Genomics of Pathogenic Protozoa Consortium (SGPP) | | 登録日 | 2004-06-18 | | 公開日 | 2004-12-21 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structure of a ribulose 5-phosphate 3-epimerase from Plasmodium falciparum.
Proteins, 62, 2006
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1SQ6
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4YRC
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4YRM
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4YRK
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4YRP
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4YRO
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4YRL
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4YPF
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4YRT
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4YRJ
 | | Crystal structure of T. cruzi Histidyl-tRNA synthetase in complex with 4-chlorobenzene-1,2-diamine (Chem 256) | | 分子名称: | 1,2-ETHANEDIOL, 4-chlorobenzene-1,2-diamine, DIMETHYL SULFOXIDE, ... | | 著者 | Koh, C.-Y, Hol, W.G.J. | | 登録日 | 2015-03-15 | | 公開日 | 2015-08-12 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | A binding hotspot in Trypanosoma cruzi histidyl-tRNA synthetase revealed by fragment-based crystallographic cocktail screens.
Acta Crystallogr. D Biol. Crystallogr., 71, 2015
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4YRS
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4YRF
 | | Crystal structure of T. cruzi Histidyl-tRNA synthetase in complex with 5-bromopyridin-2(1H)-one (Chem 148) | | 分子名称: | 1,2-ETHANEDIOL, 5-bromopyridin-2(1H)-one, DIMETHYL SULFOXIDE, ... | | 著者 | Koh, C.-Y, Hol, W.G.J. | | 登録日 | 2015-03-15 | | 公開日 | 2015-08-19 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | A binding hotspot in Trypanosoma cruzi histidyl-tRNA synthetase revealed by fragment-based crystallographic cocktail screens.
Acta Crystallogr.,Sect.D, 71, 2015
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4YRN
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4ZT2
 | | Trypanosoma brucei methionyl-tRNA synthetase in complex with inhibitor N-(3,5-dichlorobenzyl)-N'-(1H-imidazo[4,5-b]pyridin-2-yl)propane-1,3-diamine (Chem 1575) | | 分子名称: | DIMETHYL SULFOXIDE, GLYCEROL, METHIONINE, ... | | 著者 | Koh, C.-Y, Hol, W.G.J. | | 登録日 | 2015-05-14 | | 公開日 | 2016-05-04 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | 5-Fluoroimidazo[4,5-b]pyridine Is a Privileged Fragment That Conveys Bioavailability to Potent Trypanosomal Methionyl-tRNA Synthetase Inhibitors.
Acs Infect Dis., 2, 2016
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4ZT3
 | | Trypanosoma brucei methionyl-tRNA synthetase in complex with inhibitor N-(3,5-dichlorobenzyl)-N'-(5-fluoro-1H-imidazo[4,5-b]pyridin-2-yl)propane-1,3-diamine (Chem 1614) | | 分子名称: | DIMETHYL SULFOXIDE, GLYCEROL, METHIONINE, ... | | 著者 | Koh, C.-Y, Hol, W.G.J. | | 登録日 | 2015-05-14 | | 公開日 | 2016-05-04 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | 5-Fluoroimidazo[4,5-b]pyridine Is a Privileged Fragment That Conveys Bioavailability to Potent Trypanosomal Methionyl-tRNA Synthetase Inhibitors.
Acs Infect Dis., 2, 2016
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4ZT7
 | | Trypanosoma brucei methionyl-tRNA synthetase in complex with inhibitor N-[(4R)-6,8-dichloro-1,2,3,4-tetrahydroquinolin-4-yl]-N'-(5-fluoro-3H-imidazo[4,5-b]pyridin-2-yl)propane-1,3-diamine (Chem 1717) | | 分子名称: | DIMETHYL SULFOXIDE, GLYCEROL, METHIONINE, ... | | 著者 | Koh, C.-Y, Hol, W.G.J. | | 登録日 | 2015-05-14 | | 公開日 | 2016-05-04 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | 5-Fluoroimidazo[4,5-b]pyridine Is a Privileged Fragment That Conveys Bioavailability to Potent Trypanosomal Methionyl-tRNA Synthetase Inhibitors.
Acs Infect Dis., 2, 2016
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4YP0
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