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1XXA
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BU of 1xxa by Molmil
C-TERMINAL DOMAIN OF ESCHERICHIA COLI ARGININE REPRESSOR/ L-ARGININE COMPLEX; PB DERIVATIVE
Descriptor: ARGININE, ARGININE REPRESSOR, LEAD (II) ION
Authors:Van Duyne, G.D, Ghosh, G, Maas, W.K, Sigler, P.B.
Deposit date:1995-11-03
Release date:1996-03-08
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure of the oligomerization and L-arginine binding domain of the arginine repressor of Escherichia coli.
J.Mol.Biol., 256, 1996
1XXB
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BU of 1xxb by Molmil
C-TERMINAL DOMAIN OF ESCHERICHIA COLI ARGININE REPRESSOR/ L-ARGININE COMPLEX
Descriptor: ARGININE, ARGININE REPRESSOR
Authors:Van Duyne, G.D, Ghosh, G, Maas, W.K, Sigler, P.B.
Deposit date:1995-11-03
Release date:1996-03-08
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structure of the oligomerization and L-arginine binding domain of the arginine repressor of Escherichia coli.
J.Mol.Biol., 256, 1996
1XXC
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BU of 1xxc by Molmil
C-TERMINAL DOMAIN OF ESCHERICHIA COLI ARGININE REPRESSOR
Descriptor: ARGININE REPRESSOR
Authors:Van Duyne, G.D, Ghosh, G, Maas, W.K, Sigler, P.B.
Deposit date:1995-11-03
Release date:1996-03-08
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structure of the oligomerization and L-arginine binding domain of the arginine repressor of Escherichia coli.
J.Mol.Biol., 256, 1996
1FKB
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BU of 1fkb by Molmil
ATOMIC STRUCTURE OF THE RAPAMYCIN HUMAN IMMUNOPHILIN FKBP-12 COMPLEX
Descriptor: FK506 BINDING PROTEIN, RAPAMYCIN IMMUNOSUPPRESSANT DRUG
Authors:Van Duyne, G.D, Standaert, R.F, Schreiber, S.L, Clardy, J.C.
Deposit date:1992-07-02
Release date:1993-10-31
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Atomic Structure of the Rapamycin Human Immunophilin Fkbp-12 Complex
J.Am.Chem.Soc., 113, 1991
5CRX
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BU of 5crx by Molmil
ASYMMETRIC DNA-BENDING IN THE CRE-LOXP SITE-SPECIFIC RECOMBINATION SYNAPSE
Descriptor: DNA (35-MER), PROTEIN (BACTERIOPHAGE P1 CRE GENE)
Authors:Guo, F, Gopaul, D.N, Van Duyne, G.D.
Deposit date:1999-04-21
Release date:1999-07-07
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Asymmetric DNA bending in the Cre-loxP site-specific recombination synapse.
Proc.Natl.Acad.Sci.USA, 96, 1999
4CRX
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BU of 4crx by Molmil
ASYMMETRIC DNA-BENDING IN THE CRE-LOXP SITE-SPECIFIC RECOMBINATION SYNAPSE
Descriptor: DNA (35 NUCLEOTIDE CRE RECOGNITION SITE), PROTEIN (CRE RECOMBINASE)
Authors:Guo, F, Gopaul, D.N, Van Duyne, G.D.
Deposit date:1999-04-20
Release date:1999-06-14
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Asymmetric DNA bending in the Cre-loxP site-specific recombination synapse.
Proc.Natl.Acad.Sci.USA, 96, 1999
4RG5
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BU of 4rg5 by Molmil
Crystal Structure of S. Pombe SMN YG-Dimer
Descriptor: MALONATE ION, Maltose-binding periplasmic protein, Survival Motor Neuron protein chimera, ...
Authors:Gupta, K, Martin, R.S, Sarachan, K.L, Sharp, B, Van Duyne, G.D.
Deposit date:2014-09-29
Release date:2015-07-01
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Oligomeric Properties of Survival Motor NeuronGemin2 Complexes.
J.Biol.Chem., 290, 2015
5UAE
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BU of 5uae by Molmil
Crystal structure of the coiled-coil domain from Listeria Innocua Phage Integrase (Trigonal Form)
Descriptor: CITRATE ANION, Putative integrase
Authors:Gupta, K, Sharp, R, Yuan, J.B, Van Duyne, G.D.
Deposit date:2016-12-19
Release date:2017-05-24
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Coiled-coil interactions mediate serine integrase directionality.
Nucleic Acids Res., 45, 2017
5UDO
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BU of 5udo by Molmil
Crystal structure of the coiled-coil domain from Listeria Innocua Phage Integrase (Tetragonal Form II)
Descriptor: A118 serine integrase
Authors:Gupta, K, Yuan, J.B, Sharp, R, Van Duyne, G.D.
Deposit date:2016-12-28
Release date:2017-06-07
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.541 Å)
Cite:Coiled-coil interactions mediate serine integrase directionality.
Nucleic Acids Res., 45, 2017
5U96
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BU of 5u96 by Molmil
Crystal structure of the coiled-coil domain from Listeria Innocua (Tetragonal Form)
Descriptor: Putative integrase
Authors:Gupta, K, Van Duyne, G.D, Sharp, R, Yuan, J.B.
Deposit date:2016-12-15
Release date:2017-05-24
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Coiled-coil interactions mediate serine integrase directionality.
Nucleic Acids Res., 45, 2017
6DNW
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BU of 6dnw by Molmil
Sequence Requirements of the Listeria innocua prophage attP site
Descriptor: DNA (26-MER), Putative integrase [Bacteriophage A118], ZINC ION
Authors:Li, H, Sharp, R, Rutherford, K, Gupta, K, Van Duyne, G.D.
Deposit date:2018-06-08
Release date:2018-10-03
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.849 Å)
Cite:Serine Integrase attP Binding and Specificity.
J. Mol. Biol., 430, 2018
1B4B
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BU of 1b4b by Molmil
STRUCTURE OF THE OLIGOMERIZATION DOMAIN OF THE ARGININE REPRESSOR FROM BACILLUS STEAROTHERMOPHILUS
Descriptor: ARGININE, ARGININE REPRESSOR
Authors:Ni, J, Sakanyan, V, Charlier, D, Glansdorff, N, Van Duyne, G.D.
Deposit date:1998-12-18
Release date:1999-06-15
Last modified:2023-08-02
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure of the arginine repressor from Bacillus stearothermophilus.
Nat.Struct.Biol., 6, 1999
5E6F
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BU of 5e6f by Molmil
Canarypox virus resolvase
Descriptor: CNPV261 Holliday junction resolvase protein, D(-)-TARTARIC ACID, MAGNESIUM ION
Authors:Li, H, Hwang, Y, Perry, K, Bushman, F.D, Van Duyne, G.D.
Deposit date:2015-10-09
Release date:2016-03-30
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structure and Metal Binding Properties of a Poxvirus Resolvase.
J.Biol.Chem., 291, 2016
5HOT
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BU of 5hot by Molmil
Structural Basis for Inhibitor-Induced Aggregation of HIV-1 Integrase
Descriptor: (2S)-tert-butoxy[4-(8-fluoro-5-methyl-3,4-dihydro-2H-chromen-6-yl)-2-methyl-1-oxo-1,2-dihydroisoquinolin-3-yl]ethanoic acid, Integrase
Authors:Gupta, K, Turkki, V, Sherrill-Mix, S, Hwang, Y, Eilers, G, Taylor, L, McDanal, C, Wang, P, Temelkoff, D, Nolte, R, Velthuisen, E, Jeffrey, J, Van Duyne, G.D, Bushman, F.D.
Deposit date:2016-01-19
Release date:2016-12-14
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (4.4 Å)
Cite:Structural Basis for Inhibitor-Induced Aggregation of HIV Integrase.
PLoS Biol., 14, 2016
1P27
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BU of 1p27 by Molmil
Crystal Structure of the Human Y14/Magoh complex
Descriptor: Mago nashi protein homolog, RNA-binding protein 8A
Authors:Lau, C.K, Diem, M.D, Dreyfuss, G, Van Duyne, G.D.
Deposit date:2003-04-14
Release date:2003-08-19
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure of the y14-magoh core of the exon junction complex.
Curr.Biol., 13, 2003
4KIS
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BU of 4kis by Molmil
Crystal Structure of a LSR-DNA Complex
Descriptor: CALCIUM ION, DNA (26-MER), Putative integrase [Bacteriophage A118], ...
Authors:Rutherford, K, Yuan, P, Perry, K, Van Duyne, G.D.
Deposit date:2013-05-02
Release date:2013-07-10
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Attachment site recognition and regulation of directionality by the serine integrases.
Nucleic Acids Res., 41, 2013
3MGV
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BU of 3mgv by Molmil
Cre recombinase-DNA transition state
Descriptor: DNA (5'-D(*CP*AP*TP*AP*TP*GP*CP*TP*AP*TP*AP*CP*GP*AP*AP*GP*TP*TP*AP*T)-3'), DNA (5'-D(*TP*AP*TP*AP*AP*CP*TP*TP*CP*GP*TP*AP*TP*AP*G)-3'), Recombinase cre, ...
Authors:Gibb, B.P, Gupta, K, Ghosh, K, Sharp, R, Chen, J, Van Duyne, G.D.
Deposit date:2010-04-07
Release date:2010-05-26
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.29 Å)
Cite:Requirements for catalysis in the Cre recombinase active site.
Nucleic Acids Res., 38, 2010
3IGC
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BU of 3igc by Molmil
Smallpox virus topoisomerase-DNA transition state
Descriptor: 5'-D(*AP*TP*TP*CP*C)-3', 5'-D(*CP*GP*GP*AP*AP*TP*AP*AP*GP*GP*GP*CP*GP*AP*CP*A)-3', 5'-D(*GP*TP*GP*TP*CP*GP*CP*CP*CP*TP*T)-3', ...
Authors:Perry, K, Hwang, Y, Bushman, F.D, Van Duyne, G.D.
Deposit date:2009-07-27
Release date:2010-03-02
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Insights from the Structure of a Smallpox Virus Topoisomerase-DNA Transition State Mimic.
Structure, 18, 2010
4GLI
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BU of 4gli by Molmil
Crystal Structure of Human SMN YG-Dimer
Descriptor: Maltose-binding periplasmic protein, Survival motor neuron protein chimera
Authors:Martin, R.S, Perry, K, Van Duyne, G.D.
Deposit date:2012-08-14
Release date:2012-10-17
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.903 Å)
Cite:The survival motor neuron protein forms soluble glycine zipper oligomers.
Structure, 20, 2012
3C28
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BU of 3c28 by Molmil
Crystal structure of the product synapse complex
Descriptor: LoxP DNA, chain C, chain D, ...
Authors:Ghosh, K, Van Duyne, G.D.
Deposit date:2008-01-24
Release date:2009-02-17
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Detailed study on Synapsis in Cre-loxP recombination reaction
To be Published
3BVP
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BU of 3bvp by Molmil
Crystal Structure of the N-terminal Catalytic Domain of TP901-1 Integrase
Descriptor: TP901-1 Integrase
Authors:Yuan, P, Van Duyne, G.D.
Deposit date:2008-01-07
Release date:2008-08-12
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Tetrameric structure of a serine integrase catalytic domain.
Structure, 16, 2008
3C29
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BU of 3c29 by Molmil
Cre-loxP Synaptic structure
Descriptor: LoxP DNA, chain C,, chain D,F, ...
Authors:Ghosh, K, Van Duyne, G.D.
Deposit date:2008-01-24
Release date:2009-02-17
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Synapsis study in detail
To be Published
2H7G
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BU of 2h7g by Molmil
Structure of variola topoisomerase non-covalently bound to DNA
Descriptor: 5'-D(*TP*AP*AP*TP*AP*AP*GP*GP*GP*CP*GP*AP*CP*A)-3', 5'-D(*TP*TP*GP*TP*CP*GP*CP*CP*CP*TP*TP*A)-3', DNA topoisomerase 1
Authors:Perry, K, Hwang, Y, Bushman, F.D, Van Duyne, G.D.
Deposit date:2006-06-02
Release date:2006-08-15
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural basis for specificity in the poxvirus topoisomerase.
Mol.Cell, 23, 2006
2HOI
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BU of 2hoi by Molmil
Crystal structure of the tetrameric pre-cleavage synaptic complex in the cre-loxp site-specific recombination
Descriptor: LoxP DNA, Recombinase Cre
Authors:Ghosh, K, Van Duyne, G.D.
Deposit date:2006-07-14
Release date:2007-06-26
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.601 Å)
Cite:Synapsis of loxP sites by Cre recombinase.
J.Biol.Chem., 282, 2007
2HOF
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BU of 2hof by Molmil
Crystal structure of the pre-cleavage synaptic complex in the cre-loxp site-specific recombination
Descriptor: LoxP DNA, Recombinase cre
Authors:Ghosh, K, Van Duyne, G.D.
Deposit date:2006-07-14
Release date:2007-06-26
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Synapsis of loxP sites by Cre recombinase.
J.Biol.Chem., 282, 2007

 

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