1RY6
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![BU of 1ry6 by Molmil](/molmil-images/mine/1ry6) | Crystal Structure of Internal Kinesin Motor Domain | Descriptor: | INTERNAL KINESIN, SULFATE ION | Authors: | Shipley, K, Hekmat-Nejad, M, Turner, J, Moores, C, Anderson, R, Milligan, R, Sakowicz, R, Fletterick, R. | Deposit date: | 2003-12-19 | Release date: | 2004-04-13 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Structure of a kinesin microtubule depolymerization machine. Embo J., 23, 2004
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2OSR
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![BU of 2osr by Molmil](/molmil-images/mine/2osr) | NMR Structure of RRM-2 of Yeast NPL3 Protein | Descriptor: | Nucleolar protein 3 | Authors: | Deka, P, Bucheli, M, Skrisovska, L, Allain, F.H, Moore, C, Buratowski, S, Varani, G. | Deposit date: | 2007-02-06 | Release date: | 2007-12-18 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Structure of the yeast SR protein Npl3 and Interaction with mRNA 3'-end processing signals. J.Mol.Biol., 375, 2008
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2OSQ
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![BU of 2osq by Molmil](/molmil-images/mine/2osq) | NMR Structure of RRM-1 of Yeast NPL3 Protein | Descriptor: | Nucleolar protein 3 | Authors: | Deka, P, Bucheli, M, Skrisovska, L, Allain, F.H, Moore, C, Buratowski, S, Varani, G. | Deposit date: | 2007-02-06 | Release date: | 2007-12-18 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Structure of the yeast SR protein Npl3 and Interaction with mRNA 3'-end processing signals. J.Mol.Biol., 375, 2008
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2J8P
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![BU of 2j8p by Molmil](/molmil-images/mine/2j8p) | NMR structure of C-terminal domain of human CstF-64 | Descriptor: | CLEAVAGE STIMULATION FACTOR 64 KDA SUBUNIT | Authors: | Qu, X, Perez-Canadillas, J.M, Agrawal, S, De Baecke, J, Cheng, H, Varani, G, Moore, C. | Deposit date: | 2006-10-27 | Release date: | 2006-11-06 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | The C-Terminal Domains of Vertebrate Cstf-64 and its Yeast Orthologue RNA15 Form a New Structure Critical for Mrna 3'-End Processing. J.Biol.Chem., 282, 2007
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4UXS
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![BU of 4uxs by Molmil](/molmil-images/mine/4uxs) | Conserved mechanisms of microtubule-stimulated ADP release, ATP binding, and force generation in transport kinesins | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, KINESIN-3 MOTOR DOMAIN, ... | Authors: | Atherton, J, Farabella, I, Yu, I.M, Rosenfeld, S.S, Houdusse, A, Topf, M, Moores, C. | Deposit date: | 2014-08-27 | Release date: | 2014-09-24 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (7 Å) | Cite: | Conserved Mechanisms of Microtubule-Stimulated Adp Release, ATP Binding, and Force Generation in Transport Kinesins. Elife, 3, 2014
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4UXT
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![BU of 4uxt by Molmil](/molmil-images/mine/4uxt) | Conserved mechanisms of microtubule-stimulated ADP release, ATP binding, and force generation in transport kinesins | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, KINESIN HEAVY CHAIN ISOFORM 5A, ... | Authors: | Atherton, J, Farabella, I, Yu, I.M, Rosenfeld, S.S, Houdusse, A, Topf, M, Moores, C. | Deposit date: | 2014-08-27 | Release date: | 2014-09-24 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (7.4 Å) | Cite: | Conserved Mechanisms of Microtubule-Stimulated Adp Release, ATP Binding, and Force Generation in Transport Kinesins. Elife, 3, 2014
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4UXR
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![BU of 4uxr by Molmil](/molmil-images/mine/4uxr) | Conserved mechanisms of microtubule-stimulated ADP release, ATP binding, and force generation in transport kinesins | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ... | Authors: | Atherton, J, Farabella, I, Yu, I.M, Rosenfeld, S.S, Houdusse, A, Topf, M, Moores, C. | Deposit date: | 2014-08-27 | Release date: | 2014-09-24 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (7 Å) | Cite: | Conserved Mechanisms of Microtubule-Stimulated Adp Release, ATP Binding, and Force Generation in Transport Kinesins. Elife, 3, 2014
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4UY0
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![BU of 4uy0 by Molmil](/molmil-images/mine/4uy0) | Conserved mechanisms of microtubule-stimulated ADP release, ATP binding, and force generation in transport kinesins | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ... | Authors: | Atherton, J, Farabella, I, Yu, I.M, Rosenfeld, S.S, Houdusse, A, Topf, M, Moores, C. | Deposit date: | 2014-08-27 | Release date: | 2014-09-24 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (7.7 Å) | Cite: | Conserved Mechanisms of Microtubule-Stimulated Adp Release, ATP Binding, and Force Generation in Transport Kinesins. Elife, 3, 2014
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4UXO
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![BU of 4uxo by Molmil](/molmil-images/mine/4uxo) | Conserved mechanisms of microtubule-stimulated ADP release, ATP binding, and force generation in transport kinesins | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, KINESIN-3 MOTOR DOMAIN, ... | Authors: | Atherton, J, Farabella, I, Yu, I.M, Rosenfeld, S.S, Houdusse, A, Topf, M, Moores, C. | Deposit date: | 2014-08-27 | Release date: | 2014-09-24 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (6.3 Å) | Cite: | Conserved Mechanisms of Microtubule-Stimulated Adp Release, ATP Binding, and Force Generation in Transport Kinesins. Elife, 3, 2014
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4UXP
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![BU of 4uxp by Molmil](/molmil-images/mine/4uxp) | Conserved mechanisms of microtubule-stimulated ADP release, ATP binding, and force generation in transport kinesins | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, KINESIN-3 MOTOR DOMAIN, ... | Authors: | Atherton, J, Farabella, I, Yu, I.M, Rosenfeld, S.S, Houdusse, A, Topf, M, Moores, C. | Deposit date: | 2014-08-27 | Release date: | 2014-09-24 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (6.3 Å) | Cite: | Conserved Mechanisms of Microtubule-Stimulated Adp Release, ATP Binding, and Force Generation in Transport Kinesins. Elife, 3, 2014
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4UXY
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![BU of 4uxy by Molmil](/molmil-images/mine/4uxy) | Conserved mechanisms of microtubule-stimulated ADP release, ATP binding, and force generation in transport kinesins | Descriptor: | ALPHA TUBULIN, BETA TUBULIN, GUANOSINE-5'-DIPHOSPHATE, ... | Authors: | Atherton, J, Farabella, I, Yu, I.M, Rosenfeld, S.S, Houdusse, A, Topf, M, Moores, C. | Deposit date: | 2014-08-27 | Release date: | 2014-09-24 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (6.5 Å) | Cite: | Conserved Mechanisms of Microtubule-Stimulated Adp Release, ATP Binding, and Force Generation in Transport Kinesins. Elife, 3, 2014
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6YW6
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![BU of 6yw6 by Molmil](/molmil-images/mine/6yw6) | Cryo-EM structure of the ARP2/3 1B5CL isoform complex. | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, ARPC1B, Actin-related protein 2, ... | Authors: | von Loeffelholz, O, Moores, C, Purkiss, A. | Deposit date: | 2020-04-29 | Release date: | 2020-07-22 | Last modified: | 2024-05-22 | Method: | ELECTRON MICROSCOPY (4.2 Å) | Cite: | Cryo-EM of human Arp2/3 complexes provides structural insights into actin nucleation modulation by ARPC5 isoforms. Biol Open, 9, 2020
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6YW7
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![BU of 6yw7 by Molmil](/molmil-images/mine/6yw7) | Cryo-EM structure of the ARP2/3 1A5C isoform complex. | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Actin-related protein 2, Actin-related protein 2/3 complex subunit 1A, ... | Authors: | von Loeffelholz, O, Moores, C, Purkiss, A. | Deposit date: | 2020-04-29 | Release date: | 2020-07-22 | Last modified: | 2024-05-22 | Method: | ELECTRON MICROSCOPY (4.5 Å) | Cite: | Cryo-EM of human Arp2/3 complexes provides structural insights into actin nucleation modulation by ARPC5 isoforms. Biol Open, 9, 2020
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4AQW
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![BU of 4aqw by Molmil](/molmil-images/mine/4aqw) | Model of human kinesin-5 motor domain (1II6, 3HQD) and mammalian tubulin heterodimer (1JFF) docked into the 9.5-angstrom cryo-EM map of microtubule-bound kinesin-5 motor domain in the rigor state. | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, KINESIN-LIKE PROTEIN KIF11, ... | Authors: | Goulet, A, Behnke-Parks, W.M, Sindelar, C.V, Rosenfeld, S.S, Moores, C.A. | Deposit date: | 2012-04-19 | Release date: | 2012-11-21 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (9.5 Å) | Cite: | The Structural Basis of Force Generation by the Mitotic Motor Kinesin-5. J.Biol.Chem., 287, 2012
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4AQV
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![BU of 4aqv by Molmil](/molmil-images/mine/4aqv) | Model of human kinesin-5 motor domain (3HQD) and mammalian tubulin heterodimer (1JFF) docked into the 9.7-angstrom cryo-EM map of microtubule-bound kinesin-5 motor domain in the AMPPPNP state. | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, KINESIN-LIKE PROTEIN KIF11, ... | Authors: | Goulet, A, Behnke-Parks, W.M, Sindelar, C.V, Rosenfeld, S.S, Moores, C.A. | Deposit date: | 2012-04-19 | Release date: | 2012-11-21 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (9.7 Å) | Cite: | The Structural Basis of Force Generation by the Mitotic Motor Kinesin-5. J.Biol.Chem., 287, 2012
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4CK6
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![BU of 4ck6 by Molmil](/molmil-images/mine/4ck6) | Pseudo-atomic model of microtubule-bound human kinesin-5 motor domain in the ADP.AlFx state, based on cryo-electron microscopy experiment. | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, GUANOSINE-5'-DIPHOSPHATE, ... | Authors: | Goulet, A, Major, J, Jun, Y, Gross, S, Rosenfeld, S, Moores, C. | Deposit date: | 2013-12-30 | Release date: | 2014-02-05 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (9.2 Å) | Cite: | Comprehensive Structural Model of the Mechanochemical Cycle of a Mitotic Motor Highlights Molecular Adaptations in the Kinesin Family. Proc.Natl.Acad.Sci.USA, 111, 2014
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4CK7
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![BU of 4ck7 by Molmil](/molmil-images/mine/4ck7) | Pseudo-atomic model of microtubule-bound human kinesin-5 motor domain in presence of adp.alfx (NECK-LINKER IN ITS DISCONNECTED CONFORMATION, based on cryo-electron microscopy experiment | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, GUANOSINE-5'-DIPHOSPHATE, ... | Authors: | Goulet, A, Major, J, Jun, Y, Gross, S, Rosenfeld, S, Moores, C. | Deposit date: | 2013-12-30 | Release date: | 2014-02-05 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (9.2 Å) | Cite: | Comprehensive Structural Model of the Mechanochemical Cycle of a Mitotic Motor Highlights Molecular Adaptations in the Kinesin Family. Proc.Natl.Acad.Sci.USA, 111, 2014
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4CK5
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![BU of 4ck5 by Molmil](/molmil-images/mine/4ck5) | Pseudo-atomic model of microtubule-bound human kinesin-5 motor domain in the ADP state, based on cryo-electron microscopy experiment. | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ... | Authors: | Goulet, A, Major, J, Jun, Y, Gross, S, Rosenfeld, S, Moores, C. | Deposit date: | 2013-12-30 | Release date: | 2014-02-05 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (10 Å) | Cite: | Comprehensive Structural Model of the Mechanochemical Cycle of a Mitotic Motor Highlights Molecular Adaptations in the Kinesin Family. Proc.Natl.Acad.Sci.USA, 111, 2014
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5MM7
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![BU of 5mm7 by Molmil](/molmil-images/mine/5mm7) | |
5MM4
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![BU of 5mm4 by Molmil](/molmil-images/mine/5mm4) | |
5MJS
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![BU of 5mjs by Molmil](/molmil-images/mine/5mjs) | S. pombe microtubule copolymerized with GTP and Mal3-143 | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, Microtubule integrity protein mal3, ... | Authors: | von Loeffelholz, O, Moores, C. | Deposit date: | 2016-12-01 | Release date: | 2017-12-20 | Last modified: | 2019-10-23 | Method: | ELECTRON MICROSCOPY (4.6 Å) | Cite: | Nucleotide- and Mal3-dependent changes in fission yeast microtubules suggest a structural plasticity view of dynamics. Nat Commun, 8, 2017
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7OG3
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![BU of 7og3 by Molmil](/molmil-images/mine/7og3) | IRED-88 | Descriptor: | NAD(P)-dependent oxidoreductase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, SODIUM ION | Authors: | Faller, M, Koch, E. | Deposit date: | 2021-05-06 | Release date: | 2021-10-06 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.904 Å) | Cite: | Machine-Directed Evolution of an Imine Reductase for Activity and Stereoselectivity Acs Catalysis, 2021
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3C66
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![BU of 3c66 by Molmil](/molmil-images/mine/3c66) | Yeast poly(A) polymerase in complex with Fip1 residues 80-105 | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, GLYCEROL, Poly(A) polymerase, ... | Authors: | Bohm, A, Meinke, G. | Deposit date: | 2008-02-02 | Release date: | 2008-05-20 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structure of yeast poly(A) polymerase in complex with a peptide from Fip1, an intrinsically disordered protein. Biochemistry, 47, 2008
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6G76
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![BU of 6g76 by Molmil](/molmil-images/mine/6g76) | |
6G78
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![BU of 6g78 by Molmil](/molmil-images/mine/6g78) | RSK4 N-terminal Kinase Domain S232E in complex with AMP-PNP | Descriptor: | PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Ribosomal protein S6 kinase alpha-6 | Authors: | Prischi, F, Ali, M.M. | Deposit date: | 2018-04-04 | Release date: | 2019-04-17 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Repurposed floxacins targeting RSK4 prevent chemoresistance and metastasis in lung and bladder cancer. Sci Transl Med, 13, 2021
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