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Structural characterization of two b-KTx scorpion toxins. One of them blocks human KCNQ1 potassium channels
Descriptor:	Potassium channel toxin TcoKIK
Authors:	del Rio-Portilla, F, Lopez-Giraldo, A.E.
Deposit date:	2021-01-20
Release date:	2021-12-29
Last modified:	2024-10-30
Method:	SOLUTION NMR
Cite:	b-KTx scorpion toxin blocks human KCNQ1 potassium channels To Be Published

7LUW

Structural studies about ScnTx neurotoxin using Solution NMR 2D and 3D
Descriptor:	Short-chain neurotoxin
Authors:	del Rio-Portilla, F, Lopez-Giraldo, A.E.
Deposit date:	2021-02-23
Release date:	2021-04-14
Last modified:	2024-10-09
Method:	SOLUTION NMR
Cite:	The Three-Dimensional Structure of the Neurotoxin SCNTX To Be Published

1QKL

hRPABC14.4, essential subunit of human RNA polymerases I, II and III
Descriptor:	DNA-DIRECTED RNA POLYMERASE II 14.4 KD POLYPEPTIDE
Authors:	Del Rio-Portilla, F, Gaskell, A.G, Gilbert, D, Ladias, J.A.A, Wagner, G.
Deposit date:	1999-07-26
Release date:	1999-11-07
Last modified:	2024-05-15
Method:	SOLUTION NMR
Cite:	Solution Structure of the Hrpabc14.4 Subunit of Human RNA Polymerases Nat.Struct.Biol., 6, 1999

1PE4

SOLUTION STRUCTURE OF TOXIN CN12 FROM CENTRUROIDES NOXIUS ALFA SCORPION TOXIN ACTING ON SODIUM CHANNELS. NMR STRUCTURE
Descriptor:	Neurotoxin Cn11
Authors:	Del Rio-Portilla, F, Hernandez-Marin, E, Pimienta, G, Coronas, F.V, Zamudio, F.Z, Rodrguez de la Vega, R.C, Wanke, E, Possani, L.D.
Deposit date:	2003-05-21
Release date:	2004-05-25
Last modified:	2024-10-30
Method:	SOLUTION NMR
Cite:	NMR solution structure of Cn12, a novel peptide from the Mexican scorpion Centruroides noxius with a typical beta-toxin sequence but with alpha-like physiological activity. Eur.J.Biochem., 271, 2004

6VXW

NMR solution structure of natural scorpion toxin Cl13
Descriptor:	Beta-toxin Cl13
Authors:	del Rio Portilla, F, Delepierre, M, Lopez Giraldo, A.E.
Deposit date:	2020-02-24
Release date:	2020-07-08
Last modified:	2024-10-09
Method:	SOLUTION NMR
Cite:	The three-dimensional structure of the toxic peptide Cl13 from the scorpion Centruroides limpidus. Toxicon, 184, 2020

6VNZ

NMR solution structure of tamapin, mutant K20A
Descriptor:	Potassium channel toxin alpha-KTx 5.4
Authors:	del Rio Portilla, F, Melchor Meneses, C.M, Mayorga Flores, M.
Deposit date:	2020-01-29
Release date:	2020-07-29
Last modified:	2024-11-06
Method:	SOLUTION NMR
Cite:	Novel Blocker of Onco SK3 Channels Derived from Scorpion Toxin Tamapin and Active against Migration of Cancer Cells. Acs Med.Chem.Lett., 11, 2020

6AX2

Solution structure of Magi3 a specific insect toxin from the spider Macrothele gigas
Descriptor:	Mu-hexatoxin-Mg2a
Authors:	del Rio-Portilla, F, Titaux-Delgado, G.A, Escobedo-Gonzalez, F.C.
Deposit date:	2017-09-06
Release date:	2018-01-10
Last modified:	2024-10-23
Method:	SOLUTION NMR
Cite:	Successful refolding and NMR structure of rMagi3: A disulfide-rich insecticidal spider toxin. Protein Sci., 27, 2018

6D3T

NMR solution structure of tamapin, mutant DP30
Descriptor:	Potassium channel toxin alpha-KTx 5.4
Authors:	del Rio Portilla, F, Melchor Meneses, C.M, Titaux Delgado, G, Mayorga Flores, M.
Deposit date:	2018-04-16
Release date:	2019-07-17
Last modified:	2024-11-06
Method:	SOLUTION NMR
Cite:	Novel Blocker of Onco SK3 Channels Derived from Scorpion Toxin Tamapin and Active against Migration of Cancer Cells Acs Med.Chem.Lett., 2020

6D8H

NMR solution structure of tamapin, mutant Y31+N
Descriptor:	Potassium channel toxin alpha-KTx 5.4
Authors:	del Rio Portilla, F, Melchor Meneses, C.M, Titaux Delgado, G.A, Mayorga Flores, M.
Deposit date:	2018-04-26
Release date:	2019-05-01
Last modified:	2024-10-23
Method:	SOLUTION NMR
Cite:	Novel Blocker of Onco SK3 Channels Derived from Scorpion Toxin Tamapin and Active against Migration of Cancer Cells Acs Med.Chem.Lett., 2020

6D8T

NMR solution structure of tamapin, mutant E25K/K27E
Descriptor:	Potassium channel toxin alpha-KTx 5.4
Authors:	del Rio Portilla, F, Melchor Meneses, C.M, Titaux Delgado, G.A, Mayorga Flores, M.
Deposit date:	2018-04-26
Release date:	2019-05-01
Last modified:	2024-11-06
Method:	SOLUTION NMR
Cite:	Novel Blocker of Onco SK3 Channels Derived from Scorpion Toxin Tamapin and Active against Migration of Cancer Cells Acs Med.Chem.Lett., 2020

6D8Q

NMR solution structure of tamapin, mutant DP30/Y31+N
Descriptor:	Potassium channel toxin alpha-KTx 5.4
Authors:	del Rio Portilla, F, Melchor Meneses, C.M, Titaux Delgado, G.A, Mayorga Flores, M.
Deposit date:	2018-04-26
Release date:	2019-05-01
Last modified:	2024-10-23
Method:	SOLUTION NMR
Cite:	Novel Blocker of Onco SK3 Channels Derived from Scorpion Toxin Tamapin and Active against Migration of Cancer Cells Acs Med.Chem.Lett., 2020

6D8R

NMR solution structure of tamapin, mutant E25K
Descriptor:	Potassium channel toxin alpha-KTx 5.4
Authors:	del Rio Portilla, F, Melchor Meneses, C.M, Titaux Delgado, G.A, Mayorga Flores, M.
Deposit date:	2018-04-26
Release date:	2019-05-01
Last modified:	2024-10-23
Method:	SOLUTION NMR
Cite:	Novel Blocker of Onco SK3 Channels Derived from Scorpion Toxin Tamapin and Active against Migration of Cancer Cells Acs Med.Chem.Lett., 2020

6D8U

NMR solution structure of tamapin, mutant K20E
Descriptor:	Potassium channel toxin alpha-KTx 5.4
Authors:	del Rio Portilla, F, Melchor Meneses, C.M, Titaux Delgado, G.A, Mayorga Flores, M.
Deposit date:	2018-04-26
Release date:	2019-05-01
Last modified:	2024-11-06
Method:	SOLUTION NMR
Cite:	Novel Blocker of Onco SK3 Channels Derived from Scorpion Toxin Tamapin and Active against Migration of Cancer Cells Acs Med.Chem.Lett., 2020

6D9P

NMR solution structure of tamapin, mutant K27A
Descriptor:	Potassium channel toxin alpha-KTx 5.4
Authors:	del Rio Portilla, F, Melchor Meneses, C.M, Titaux Delgado, G.A, Mayorga Flores, M.
Deposit date:	2018-04-30
Release date:	2019-05-08
Last modified:	2023-06-14
Method:	SOLUTION NMR
Cite:	Novel Blocker of Onco SK3 Channels Derived from Scorpion Toxin Tamapin and Active against Migration of Cancer Cells Acs Med.Chem.Lett., 2020

6D8Y

NMR solution structure of tamapin, mutant Y31H
Descriptor:	Potassium channel toxin alpha-KTx 5.4
Authors:	del Rio Portilla, F, Melchor Meneses, C.M, Titaux Delgado, G.A, Mayorga Flores, M.
Deposit date:	2018-04-27
Release date:	2019-05-01
Last modified:	2024-10-09
Method:	SOLUTION NMR
Cite:	Novel Blocker of Onco SK3 Channels Derived from Scorpion Toxin Tamapin and Active against Migration of Cancer Cells Acs Med.Chem.Lett., 2020

6D93

NMR solution structure of tamapin, mutant Y31A
Descriptor:	Potassium channel toxin alpha-KTx 5.4
Authors:	del Rio Portilla, F, Melchor Meneses, C.M, Titaux Delgado, G.A, Mayorga Flores, M.
Deposit date:	2018-04-27
Release date:	2019-05-01
Last modified:	2024-10-23
Method:	SOLUTION NMR
Cite:	Novel Blocker of Onco SK3 Channels Derived from Scorpion Toxin Tamapin and Active against Migration of Cancer Cells Acs Med.Chem.Lett., 2020

6D8S

NMR solution structure of tamapin, mutant K27E
Descriptor:	Potassium channel toxin alpha-KTx 5.4
Authors:	del Rio Portilla, F, Melchor Meneses, C.M, Titaux Delgado, G.A, Mayorga Flores, M.
Deposit date:	2018-04-26
Release date:	2019-05-01
Last modified:	2024-10-16
Method:	SOLUTION NMR
Cite:	Novel Blocker of Onco SK3 Channels Derived from Scorpion Toxin Tamapin and Active against Migration of Cancer Cells Acs Med.Chem.Lett., 2020

6D9O

NMR solution structure of tamapin, mutant E25A
Descriptor:	Potassium channel toxin alpha-KTx 5.4
Authors:	del Rio Portilla, F, Melchor Meneses, C.M, Titaux Delgado, G.A, Mayorga Flores, M.
Deposit date:	2018-04-30
Release date:	2019-05-08
Last modified:	2023-06-14
Method:	SOLUTION NMR
Cite:	Novel Blocker of Onco SK3 Channels Derived from Scorpion Toxin Tamapin and Active against Migration of Cancer Cells Acs Med.Chem.Lett., 2020

2LI7

Solution Structure of CssII
Descriptor:	Beta-mammal toxin Css2
Authors:	del Rio-Portilla, F, Saucedo, A.L, Corzo, G, Delepierre, M, Possani, L.D.
Deposit date:	2011-08-24
Release date:	2012-02-15
Last modified:	2024-10-09
Method:	SOLUTION NMR
Cite:	Solution structure of native and recombinant expressed toxin CssII from the venom of the scorpion Centruroides suffusus suffusus, and their effects on Nav1.5 Sodium channels. Biochim.Biophys.Acta, 1824, 2012

2LJM

Solution Structure of CssII
Descriptor:	Beta-mammal toxin Css2
Authors:	del Rio-Portilla, F, Saucedo, A.L, Corzo, G, Delepierre, M, Possani, L.D.
Deposit date:	2011-09-20
Release date:	2012-02-15
Last modified:	2024-11-06
Method:	SOLUTION NMR
Cite:	Solution structure of native and recombinant expressed toxin CssII from the venom of the scorpion Centruroides suffusus suffusus, and their effects on Nav1.5 Sodium channels. Biochim.Biophys.Acta, 1824, 2012

2LO7

Ts16 NMR solution structure
Descriptor:	Toxin Ts16
Authors:	del Rio-Portilla, F, Saucedo, A.L, Flores-Solis, D.
Deposit date:	2012-01-17
Release date:	2012-03-14
Last modified:	2014-01-15
Method:	SOLUTION NMR
Cite:	New Tricks of an Old Pattern: STRUCTURAL VERSATILITY OF SCORPION TOXINS WITH COMMON CYSTEINE SPACING. J.Biol.Chem., 287, 2012

2K9O

Solution structure of Vm24 synthetic scorpion toxin
Descriptor:	Vm24 SCORPION toxin
Authors:	del Rio-Portilla, F, Hernandez-Lopez, R, Possani-Postay, L, Gurrola, G.
Deposit date:	2008-10-20
Release date:	2009-11-03
Last modified:	2014-05-28
Method:	SOLUTION NMR
Cite:	Structure, function, and chemical synthesis of Vaejovis mexicanus peptide 24: a novel potent blocker of Kv1.3 potassium channels of human T lymphocytes. Biochemistry, 51, 2012

2KY3

Solution structure of GS-alfa-Ktx5.4 synthetic scorpion like
Descriptor:	Potassium channel toxin alpha-KTx 5.4
Authors:	Del Rio-Portilla, F, Ramirez-Cordero, B.E, Brieba-De Castro, L.
Deposit date:	2010-05-14
Release date:	2011-06-01
Last modified:	2020-02-05
Method:	SOLUTION NMR
Cite:	Cytotoxicity of recombinant tamapin and related toxin-like peptides on model cell lines. Chem.Res.Toxicol., 27, 2014

2MEN

NMR solution structure of the GS-TAMAPIN MUTATION R13A
Descriptor:	Potassium channel toxin alpha-KTx 5.4
Authors:	del Rio-Portilla, F, Ramirez-Cordero, B.
Deposit date:	2013-09-24
Release date:	2014-05-28
Last modified:	2024-11-06
Method:	SOLUTION NMR
Cite:	Cytotoxicity of recombinant tamapin and related toxin-like peptides on model cell lines. Chem.Res.Toxicol., 27, 2014

2MEO

NMR solution structure of the double GS-Tamapin mutation R6A/R7A
Descriptor:	Potassium channel toxin alpha-KTx 5.4
Authors:	del Rio-Portilla, F, Ramirez-Cordero, B.
Deposit date:	2013-09-24
Release date:	2014-05-28
Last modified:	2014-07-02
Method:	SOLUTION NMR
Cite:	Cytotoxicity of recombinant tamapin and related toxin-like peptides on model cell lines. Chem.Res.Toxicol., 27, 2014

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Total results:	43
Displayed results:	25
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