5Z2V
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![BU of 5z2v by Molmil](/molmil-images/mine/5z2v) | Crystal structure of RecR from Pseudomonas aeruginosa PAO1 | Descriptor: | ANY 5'-MONOPHOSPHATE NUCLEOTIDE, GLYCEROL, PHOSPHATE ION, ... | Authors: | Che, S, Zhang, Q, Bartlam, M. | Deposit date: | 2018-01-04 | Release date: | 2019-01-02 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystal structure of RecR, a member of the RecFOR DNA-repair pathway, from Pseudomonas aeruginosa PAO1. Acta Crystallogr F Struct Biol Commun, 74, 2018
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6NQ3
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![BU of 6nq3 by Molmil](/molmil-images/mine/6nq3) | Crystal Structure of a SUZ12-RBBP4-PHF19-JARID2 Heterotetrameric Complex | Descriptor: | Histone-binding protein RBBP4, PHD finger protein 19, Polycomb protein SUZ12, ... | Authors: | Chen, S, Jiao, L, Liu, X. | Deposit date: | 2019-01-19 | Release date: | 2020-01-29 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.89 Å) | Cite: | A Dimeric Structural Scaffold for PRC2-PCL Targeting to CpG Island Chromatin. Mol.Cell, 77, 2020
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6NRX
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![BU of 6nrx by Molmil](/molmil-images/mine/6nrx) | Crystal structure of DIP-eta IG1 homodimer | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Dpr-interacting protein eta, isoform B, ... | Authors: | Cheng, S, Park, Y.J, Kurleto, J.D, Ozkan, E. | Deposit date: | 2019-01-24 | Release date: | 2019-02-06 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Molecular basis of synaptic specificity by immunoglobulin superfamily receptors in Drosophila. Elife, 8, 2019
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6NRW
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![BU of 6nrw by Molmil](/molmil-images/mine/6nrw) | Crystal structure of Dpr1 IG1 bound to DIP-eta IG1 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Cheng, S, Park, Y.J, Kurleto, J.D, Ozkan, E. | Deposit date: | 2019-01-24 | Release date: | 2019-02-06 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Molecular basis of synaptic specificity by immunoglobulin superfamily receptors in Drosophila. Elife, 8, 2019
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6NRQ
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![BU of 6nrq by Molmil](/molmil-images/mine/6nrq) | Crystal structure of Dpr10 IG1 bound to DIP-alpha IG1 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Defective proboscis extension response 10, isoform A, ... | Authors: | Cheng, S, Park, Y.J, Kurleto, J.D, Ozkan, E. | Deposit date: | 2019-01-24 | Release date: | 2019-02-06 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Molecular basis of synaptic specificity by immunoglobulin superfamily receptors in Drosophila. Elife, 8, 2019
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6NS1
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![BU of 6ns1 by Molmil](/molmil-images/mine/6ns1) | Crystal structure of DIP-gamma IG1+IG2 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Dpr-interacting protein gamma | Authors: | Cheng, S, Park, Y.J, Kurleto, J.D, Ozkan, E. | Deposit date: | 2019-01-24 | Release date: | 2019-02-06 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Molecular basis of synaptic specificity by immunoglobulin superfamily receptors in Drosophila. Elife, 8, 2019
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7D9J
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![BU of 7d9j by Molmil](/molmil-images/mine/7d9j) | SpdH Spermidine dehydrogenase Y443A mutant | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, PROTOPORPHYRIN IX CONTAINING FE, ... | Authors: | Che, S, Zhang, Q, Bartlam, M. | Deposit date: | 2020-10-13 | Release date: | 2021-11-17 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.19 Å) | Cite: | Structure of Pseudomonas aeruginosa spermidine dehydrogenase: a polyamine oxidase with a novel heme-binding fold. Febs J., 289, 2022
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7D9F
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![BU of 7d9f by Molmil](/molmil-images/mine/7d9f) | SpdH Spermidine dehydrogenase SeMet Structure | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, PROTOPORPHYRIN IX CONTAINING FE, ... | Authors: | Che, S, Zhang, Q, Bartlam, M. | Deposit date: | 2020-10-13 | Release date: | 2021-11-17 | Last modified: | 2022-04-20 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Structure of Pseudomonas aeruginosa spermidine dehydrogenase: a polyamine oxidase with a novel heme-binding fold. Febs J., 289, 2022
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7D9I
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![BU of 7d9i by Molmil](/molmil-images/mine/7d9i) | SpdH Spermidine dehydrogenase D282A mutant | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, PROTOPORPHYRIN IX CONTAINING FE, Spermidine dehydrogenase, ... | Authors: | Che, S, Zhang, Q, Bartlam, M. | Deposit date: | 2020-10-13 | Release date: | 2021-11-17 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structure of Pseudomonas aeruginosa spermidine dehydrogenase: a polyamine oxidase with a novel heme-binding fold. Febs J., 289, 2022
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7D9H
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![BU of 7d9h by Molmil](/molmil-images/mine/7d9h) | SpdH Spermidine dehydrogenase N33 truncation structure | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, PROTOPORPHYRIN IX CONTAINING FE, ... | Authors: | Che, S, Zhang, Q, Bartlam, M. | Deposit date: | 2020-10-13 | Release date: | 2021-11-17 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.31 Å) | Cite: | Structure of Pseudomonas aeruginosa spermidine dehydrogenase: a polyamine oxidase with a novel heme-binding fold. Febs J., 289, 2022
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7D9G
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![BU of 7d9g by Molmil](/molmil-images/mine/7d9g) | SpdH Spermidine dehydrogenase native structure | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, PROTOPORPHYRIN IX CONTAINING FE, Spermidine dehydrogenase, ... | Authors: | Che, S, Zhang, Q, Bartlam, M. | Deposit date: | 2020-10-13 | Release date: | 2021-11-17 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structure of Pseudomonas aeruginosa spermidine dehydrogenase: a polyamine oxidase with a novel heme-binding fold. Febs J., 289, 2022
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7BVW
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![BU of 7bvw by Molmil](/molmil-images/mine/7bvw) | Crystal structure of the RING-H2 domain of Arabidopsis RMR1 | Descriptor: | AT5G66160 protein, SODIUM ION, ZINC ION | Authors: | Chen, S, Wong, K.B. | Deposit date: | 2020-04-12 | Release date: | 2021-04-14 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | The RING-finger of AtRMR1 (Arabidopsis receptor-homology-transmembrane-RING-H2 sorting receptor 1) is an E3 ligase that mediate its trafficking To Be Published
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7N6Z
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![BU of 7n6z by Molmil](/molmil-images/mine/7n6z) | Crystal Structure of PI5P4KIIAlpha | Descriptor: | Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha, SULFATE ION | Authors: | Chen, S, Ha, Y. | Deposit date: | 2021-06-09 | Release date: | 2021-06-30 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Pharmacological inhibition of PI5P4K alpha / beta disrupts cell energy metabolism and selectively kills p53-null tumor cells. Proc.Natl.Acad.Sci.USA, 118, 2021
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7N7N
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![BU of 7n7n by Molmil](/molmil-images/mine/7n7n) | Crystal Structure of PI5P4KIIAlpha complex with Volasertib | Descriptor: | N-{trans-4-[4-(cyclopropylmethyl)piperazin-1-yl]cyclohexyl}-4-{[(7R)-7-ethyl-5-methyl-8-(1-methylethyl)-6-oxo-5,6,7,8-tetrahydropteridin-2-yl]amino}-3-methoxybenzamide, Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha, SULFATE ION | Authors: | Chen, S, Ha, Y. | Deposit date: | 2021-06-10 | Release date: | 2021-06-30 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Pharmacological inhibition of PI5P4K alpha / beta disrupts cell energy metabolism and selectively kills p53-null tumor cells. Proc.Natl.Acad.Sci.USA, 118, 2021
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7N7O
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![BU of 7n7o by Molmil](/molmil-images/mine/7n7o) | Crystal Structure of PI5P4KIIAlpha complex with Palbociclib | Descriptor: | 6-ACETYL-8-CYCLOPENTYL-5-METHYL-2-[(5-PIPERAZIN-1-YLPYRIDIN-2-YL)AMINO]PYRIDO[2,3-D]PYRIMIDIN-7(8H)-ONE, Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha, SULFATE ION | Authors: | Chen, S, Ha, Y. | Deposit date: | 2021-06-10 | Release date: | 2021-06-30 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Pharmacological inhibition of PI5P4K alpha / beta disrupts cell energy metabolism and selectively kills p53-null tumor cells. Proc.Natl.Acad.Sci.USA, 118, 2021
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7N81
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![BU of 7n81 by Molmil](/molmil-images/mine/7n81) | Crystal Structure of PI5P4KIIBeta complex with CC260 | Descriptor: | (7R)-8-cyclopentyl-7-(cyclopentylmethyl)-2-[(3,5-dichloro-4-hydroxyphenyl)amino]-5-methyl-7,8-dihydropteridin-6(5H)-one, Phosphatidylinositol 5-phosphate 4-kinase type-2 beta | Authors: | Chen, S, Ha, Y. | Deposit date: | 2021-06-11 | Release date: | 2021-06-30 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Pharmacological inhibition of PI5P4K alpha / beta disrupts cell energy metabolism and selectively kills p53-null tumor cells. Proc.Natl.Acad.Sci.USA, 118, 2021
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7N7J
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![BU of 7n7j by Molmil](/molmil-images/mine/7n7j) | Crystal Structure of PI5P4KIIAlpha complex with AMPPNP | Descriptor: | MANGANESE (II) ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha, ... | Authors: | Chen, S, Ha, Y. | Deposit date: | 2021-06-10 | Release date: | 2021-06-30 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Pharmacological inhibition of PI5P4K alpha / beta disrupts cell energy metabolism and selectively kills p53-null tumor cells. Proc.Natl.Acad.Sci.USA, 118, 2021
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7N80
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![BU of 7n80 by Molmil](/molmil-images/mine/7n80) | Crystal Structure of PI5P4KIIBeta | Descriptor: | Phosphatidylinositol 5-phosphate 4-kinase type-2 beta | Authors: | Chen, S, Ha, Y. | Deposit date: | 2021-06-11 | Release date: | 2021-06-30 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Pharmacological inhibition of PI5P4K alpha / beta disrupts cell energy metabolism and selectively kills p53-null tumor cells. Proc.Natl.Acad.Sci.USA, 118, 2021
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7N7M
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![BU of 7n7m by Molmil](/molmil-images/mine/7n7m) | Crystal Structure of PI5P4KIIAlpha complex with BI-2536 | Descriptor: | 4-{[(7R)-8-cyclopentyl-7-ethyl-5-methyl-6-oxo-5,6,7,8-tetrahydropteridin-2-yl]amino}-3-methoxy-N-(1-methylpiperidin-4-yl)benzamide, Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha, SULFATE ION | Authors: | Chen, S, Ha, Y. | Deposit date: | 2021-06-10 | Release date: | 2021-06-30 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Pharmacological inhibition of PI5P4K alpha / beta disrupts cell energy metabolism and selectively kills p53-null tumor cells. Proc.Natl.Acad.Sci.USA, 118, 2021
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7N7K
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![BU of 7n7k by Molmil](/molmil-images/mine/7n7k) | Crystal Structure of PI5P4KIIAlpha complex with AMPPNP | Descriptor: | MANGANESE (II) ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha, ... | Authors: | Chen, S, Ha, Y. | Deposit date: | 2021-06-10 | Release date: | 2021-06-30 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Pharmacological inhibition of PI5P4K alpha / beta disrupts cell energy metabolism and selectively kills p53-null tumor cells. Proc.Natl.Acad.Sci.USA, 118, 2021
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7N7L
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![BU of 7n7l by Molmil](/molmil-images/mine/7n7l) | Crystal Structure of PI5P4KIIAlpha complex with BI-D1870 | Descriptor: | (7R)-2-[(3,5-difluoro-4-hydroxyphenyl)amino]-5,7-dimethyl-8-(3-methylbutyl)-7,8-dihydropteridin-6(5H)-one, Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha, SULFATE ION | Authors: | Chen, S, Ha, Y. | Deposit date: | 2021-06-10 | Release date: | 2021-06-30 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Pharmacological inhibition of PI5P4K alpha / beta disrupts cell energy metabolism and selectively kills p53-null tumor cells. Proc.Natl.Acad.Sci.USA, 118, 2021
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7N71
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![BU of 7n71 by Molmil](/molmil-images/mine/7n71) | Crystal Structure of PI5P4KIIAlpha | Descriptor: | Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha, SULFATE ION | Authors: | Chen, S, Ha, Y. | Deposit date: | 2021-06-09 | Release date: | 2021-07-07 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Pharmacological inhibition of PI5P4K alpha / beta disrupts cell energy metabolism and selectively kills p53-null tumor cells. Proc.Natl.Acad.Sci.USA, 118, 2021
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7P8W
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![BU of 7p8w by Molmil](/molmil-images/mine/7p8w) | Human erythrocyte catalase cryoEM | Descriptor: | Catalase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, PROTOPORPHYRIN IX CONTAINING FE | Authors: | Chen, S, Li, J, Vinothkumar, K.R, Henderson, R. | Deposit date: | 2021-07-23 | Release date: | 2021-08-25 | Last modified: | 2022-03-23 | Method: | ELECTRON MICROSCOPY (2.2 Å) | Cite: | Interaction of human erythrocyte catalase with air-water interface in cryoEM. Microscopy (Oxf), 71, 2022
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6RZ3
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![BU of 6rz3 by Molmil](/molmil-images/mine/6rz3) | Crystal structure of a complex between the DNA-binding domain of p53 and the carboxyl-terminal conserved region of iASPP | Descriptor: | Cellular tumor antigen p53, RelA-associated inhibitor, ZINC ION | Authors: | Chen, S, Ren, J, Jones, E.Y, Lu, X. | Deposit date: | 2019-06-12 | Release date: | 2019-10-30 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (4.23 Å) | Cite: | iASPP mediates p53 selectivity through a modular mechanism fine-tuning DNA recognition. Proc.Natl.Acad.Sci.USA, 116, 2019
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7Y24
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![BU of 7y24 by Molmil](/molmil-images/mine/7y24) | Cryo-EM structure of the octreotide-bound SSTR2-miniGo-scFv16 complex | Descriptor: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(o) subunit alpha, ... | Authors: | Chen, S, Zheng, S. | Deposit date: | 2022-06-09 | Release date: | 2022-10-19 | Last modified: | 2023-02-15 | Method: | ELECTRON MICROSCOPY (3.25 Å) | Cite: | Molecular basis for the selective G protein signaling of somatostatin receptors. Nat.Chem.Biol., 19, 2023
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