7N6Z

Crystal Structure of PI5P4KIIAlpha

Summary for 7N6Z

• Entry DOI: 10.2210/pdb7n6z/pdb
• Descriptor: Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha, SULFATE ION (3 entities in total)
• Functional Keywords: kinase, transferase
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 1
• Total formula weight: 43402.89

Authors

Chen, S.,Ha, Y. (deposition date: 2021-06-09, release date: 2021-06-30, Last modification date: 2023-10-18)

• Primary citation: Chen, S.,Chandra Tjin, C.,Gao, X.,Xue, Y.,Jiao, H.,Zhang, R.,Wu, M.,He, Z.,Ellman, J.,Ha, Y.; Pharmacological inhibition of PI5P4K alpha / beta disrupts cell energy metabolism and selectively kills p53-null tumor cells.; Proc.Natl.Acad.Sci.USA, 118:-, 2021; PubMed: 34001596; DOI: 10.1073/pnas.2002486118

Experimental method

X-RAY DIFFRACTION (2.2 Å)