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1SGT
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BU of 1sgt by Molmil
REFINED CRYSTAL STRUCTURE OF STREPTOMYCES GRISEUS TRYPSIN AT 1.7 ANGSTROMS RESOLUTION
Descriptor: CALCIUM ION, TRYPSIN
Authors:Read, R.J, James, M.N.G.
Deposit date:1988-04-13
Release date:1988-07-16
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Refined crystal structure of Streptomyces griseus trypsin at 1.7 A resolution.
J.Mol.Biol., 200, 1988
3SGB
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BU of 3sgb by Molmil
STRUCTURE OF THE COMPLEX OF STREPTOMYCES GRISEUS PROTEASE B AND THE THIRD DOMAIN OF THE TURKEY OVOMUCOID INHIBITOR AT 1.8 ANGSTROMS RESOLUTION
Descriptor: PROTEINASE B (SGPB), TURKEY OVOMUCOID INHIBITOR (OMTKY3)
Authors:Read, R.J, Fujinaga, M, Sielecki, A.R, James, M.N.G.
Deposit date:1983-01-21
Release date:1983-07-12
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structure of the complex of Streptomyces griseus protease B and the third domain of the turkey ovomucoid inhibitor at 1.8-A resolution.
Biochemistry, 22, 1983
1OC0
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BU of 1oc0 by Molmil
plasminogen activator inhibitor-1 complex with somatomedin B domain of vitronectin
Descriptor: PLASMINOGEN ACTIVATOR INHIBITOR-1, VITRONECTIN
Authors:Read, R.J, Zhou, A, Huntington, J.A, Pannu, N.S, Carrell, R.W.
Deposit date:2003-02-03
Release date:2003-06-19
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (2.28 Å)
Cite:How Vitronectin Binds Pai-1 to Modulate Fibrinolysis and Cell Migration
Nat.Struct.Biol., 10, 2003
1BOS
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BU of 1bos by Molmil
SHIGA-LIKE TOXIN COMPLEXED WITH ITS RECEPTOR
Descriptor: SHIGA-LIKE TOXIN I B SUBUNIT, alpha-D-galactopyranose-(1-4)-beta-D-galactopyranose, alpha-D-galactopyranose-(1-4)-beta-D-galactopyranose-(1-4)-beta-D-glucopyranose, ...
Authors:Ling, H, Boodhoo, A, Hazes, B, Cummings, M.D, Armstrong, G.D, Brunton, J.L, Read, R.J.
Deposit date:1998-01-13
Release date:1999-02-02
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structure of the shiga-like toxin I B-pentamer complexed with an analogue of its receptor Gb3.
Biochemistry, 37, 1998
1C48
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BU of 1c48 by Molmil
MUTATED SHIGA-LIKE TOXIN B SUBUNIT (G62T)
Descriptor: PROTEIN (SHIGA-LIKE TOXIN I B SUBUNIT)
Authors:Ling, H, Bast, D, Brunton, J.L, Read, R.J.
Deposit date:1999-08-11
Release date:2000-08-16
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Identification of the Primary Receptor Binding Site of Shiga-Like Toxin B Subunits: Structures of Mutated Shiga-Like Toxin I B-Pentamer with and without Bound Carbohydrate
To be Published
1C4Q
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BU of 1c4q by Molmil
MUTATED SHIGA-LIKE TOXIN B SUBUNIT (F30A/W34A) COMPLEXED WITH RECEPTOR GB3 ANALOGUE
Descriptor: PROTEIN (SHIGA-LIKE TOXIN I SUBUNIT B), alpha-D-galactopyranose-(1-4)-beta-D-galactopyranose-(1-4)-beta-D-glucopyranose
Authors:Ling, H, Brunton, J.L, Read, R.J.
Deposit date:1999-08-31
Release date:2000-09-20
Last modified:2024-11-13
Method:X-RAY DIFFRACTION (1.52 Å)
Cite:Identification of the Primary Receptor Binding Site of Shiga-Like Toxin B Subunits: Structures of Mutated Shiga-Like Toxin I B-Pentamer with and without Bound Carbohydrate
To be Published
4V0X
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BU of 4v0x by Molmil
The crystal structure of mouse PP1G in complex with truncated human PPP1R15B (631-684)
Descriptor: MANGANESE (II) ION, PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 15B, PROTEIN PHOSPHATASE PP1-GAMMA CATALYTIC SUBUNIT
Authors:Chen, R, Yan, Y, Casado, A.C, Ron, D, Read, R.J.
Deposit date:2014-09-18
Release date:2015-03-25
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:G-actin provides substrate-specificity to eukaryotic initiation factor 2 alpha holophosphatases.
Elife, 4, 2015
2BOS
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BU of 2bos by Molmil
A MUTANT SHIGA-LIKE TOXIN IIE BOUND TO ITS RECEPTOR
Descriptor: N-BUTANE, PROTEIN (SHIGA-LIKE TOXIN IIE B SUBUNIT), alpha-D-galactopyranose-(1-4)-beta-D-galactopyranose, ...
Authors:Ling, H, Boodhoo, A, Armstrong, G.D, Clark, C.G, Brunton, J.L, Read, R.J.
Deposit date:1998-10-20
Release date:1999-10-20
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2 Å)
Cite:A mutant Shiga-like toxin IIe bound to its receptor Gb(3): structure of a group II Shiga-like toxin with altered binding specificity.
Structure Fold.Des., 8, 2000
7NRB
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BU of 7nrb by Molmil
Re-refinement of MK3-inhibitor complex
Descriptor: 2-(2-QUINOLIN-3-YLPYRIDIN-4-YL)-1,5,6,7-TETRAHYDRO-4H-PYRROLO[3,2-C]PYRIDIN-4-ONE, MAP kinase-activated protein kinase 3
Authors:Croll, T.I, Read, R.J.
Deposit date:2021-03-03
Release date:2022-01-12
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Adaptive Cartesian and torsional restraints for interactive model rebuilding.
Acta Crystallogr D Struct Biol, 77, 2021
7NRY
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BU of 7nry by Molmil
Re-refinement of MAPKAP kinase-2/inhibitor complex 3fyj
Descriptor: (10R)-10-methyl-3-(6-methylpyridin-3-yl)-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one, CHLORIDE ION, MALONIC ACID, ...
Authors:Croll, T.I, Read, R.J.
Deposit date:2021-03-04
Release date:2022-02-09
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (3.8 Å)
Cite:Adaptive Cartesian and torsional restraints for interactive model rebuilding.
Acta Crystallogr D Struct Biol, 77, 2021
2C4P
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BU of 2c4p by Molmil
Crystal structure of human ubiquitin-conjugating enzyme UbcH5A
Descriptor: UBIQUITIN-CONJUGATING ENZYME E2 D1
Authors:Dodd, R.B, Read, R.J.
Deposit date:2005-10-21
Release date:2006-11-22
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Structures of Two Human Ubiquitin-Conjugating Enzymes from Twinned Crystals
To be Published
2C5C
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BU of 2c5c by Molmil
Shiga-like toxin 1 B subunit complexed with a bivalent inhibitor
Descriptor: DIETHYL PROPANE-1,3-DIYLBISCARBAMATE, SHIGA-LIKE TOXIN 1 B SUBUNIT, SULFATE ION, ...
Authors:Dodd, R.B, Read, R.J.
Deposit date:2005-10-26
Release date:2006-11-27
Last modified:2024-11-13
Method:X-RAY DIFFRACTION (2.94 Å)
Cite:Extensive Cross-Linking of the Shiga-Like Toxin 1 B Subunit by a Bivalent Ligand
To be Published
4V0V
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BU of 4v0v by Molmil
The crystal structure of mouse PP1G in complex with truncated human PPP1R15B (631-660)
Descriptor: MANGANESE (II) ION, PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 15B, SERINE/THREONINE-PROTEIN PHOSPHATASE PP1-GAMMA CATALYTIC SUBUNIT, ...
Authors:Chen, R, Yan, Y, Casado, A.C, Ron, D, Read, R.J.
Deposit date:2014-09-18
Release date:2015-03-25
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.61 Å)
Cite:G-actin provides substrate-specificity to eukaryotic initiation factor 2 alpha holophosphatases.
Elife, 4, 2015
4V0U
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BU of 4v0u by Molmil
The crystal structure of ternary PP1G-PPP1R15B and G-actin complex
Descriptor: ACTIN, ALPHA SKELETAL MUSCLE, ADENOSINE-5'-TRIPHOSPHATE, ...
Authors:Chen, R, Yan, Y, Casado, A.C, Ron, D, Read, R.J.
Deposit date:2014-09-18
Release date:2015-03-25
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (7.88 Å)
Cite:G-actin provides substrate-specificity to eukaryotic initiation factor 2 alpha holophosphatases.
Elife, 4, 2015
4V0W
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BU of 4v0w by Molmil
The crystal structure of mouse PP1G in complex with truncated human PPP1R15B (631-669)
Descriptor: MANGANESE (II) ION, PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 15B, SERINE/THREONINE-PROTEIN PHOSPHATASE PP1-GAMMA CATALYTIC SUBUNIT
Authors:Chen, R, Yan, Y, Casado, A.C, Ron, D, Read, R.J.
Deposit date:2014-09-18
Release date:2015-03-25
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:G-actin provides substrate-specificity to eukaryotic initiation factor 2 alpha holophosphatases.
Elife, 4, 2015
8CKP
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BU of 8ckp by Molmil
X-ray structure of the crystallization-prone form of subfamily III haloalkane dehalogenase DhmeA from Haloferax mediterranei
Descriptor: Alpha/beta fold hydrolase, CHLORIDE ION
Authors:Marek, M, Chmelova, K, Schenkmayerova, A, Croll, T, Read, R.J, Diederichs, K.
Deposit date:2023-02-16
Release date:2023-08-30
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3.31 Å)
Cite:Multimeric structure of a subfamily III haloalkane dehalogenase-like enzyme solved by combination of cryo-EM and x-ray crystallography.
Protein Sci., 32, 2023
4UFI
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BU of 4ufi by Molmil
Mouse Galactocerebrosidase complexed with aza-galacto-fagomine AGF
Descriptor: (3R,4S,5R)-3-(hydroxymethyl)-1,2-diazinane-4,5-diol, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Hill, C.H, Viuff, A.H, Spratley, S.J, Salamone, S, Christensen, S.H, Read, R.J, Moriarty, N.W, Jensen, H.H, Deane, J.E.
Deposit date:2015-03-17
Release date:2015-03-25
Last modified:2024-11-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Azasugar Inhibitors as Pharmacological Chaperones for Krabbe Disease.
Chem.Sci., 6, 2015
4UFK
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BU of 4ufk by Molmil
Mouse Galactocerebrosidase complexed with dideoxy-imino-lyxitol DIL
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
Authors:Hill, C.H, Viuff, A.H, Spratley, S.J, Salamone, S, Christensen, S.H, Read, R.J, Moriarty, N.W, Jensen, H.H, Deane, J.E.
Deposit date:2015-03-17
Release date:2015-03-25
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (2.402 Å)
Cite:Azasugar Inhibitors as Pharmacological Chaperones for Krabbe Disease.
Chem.Sci., 6, 2015
4UFH
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BU of 4ufh by Molmil
Mouse Galactocerebrosidase complexed with iso-galacto-fagomine IGF
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
Authors:Hill, C.H, Viuff, A.H, Spratley, S.J, Salamone, S, Christensen, S.H, Read, R.J, Moriarty, N.W, Jensen, H.H, Deane, J.E.
Deposit date:2015-03-17
Release date:2015-03-25
Last modified:2024-11-13
Method:X-RAY DIFFRACTION (2.16 Å)
Cite:Azasugar Inhibitors as Pharmacological Chaperones for Krabbe Disease.
Chem.Sci., 6, 2015
4UFL
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BU of 4ufl by Molmil
Mouse Galactocerebrosidase complexed with deoxy-galacto-noeurostegine DGN
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
Authors:Hill, C.H, Viuff, A.H, Spratley, S.J, Salamone, S, Christensen, S.H, Read, R.J, Moriarty, N.W, Jensen, H.H, Deane, J.E.
Deposit date:2015-03-17
Release date:2015-03-25
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Azasugar Inhibitors as Pharmacological Chaperones for Krabbe Disease.
Chem.Sci., 6, 2015
4UFJ
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BU of 4ufj by Molmil
Mouse Galactocerebrosidase complexed with iso-galacto-fagomine lactam IGL
Descriptor: (3S,4S,5R)-5-(hydroxymethyl)-3,4-bis(oxidanyl)piperidin-2-one, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Hill, C.H, Viuff, A.H, Spratley, S.J, Salamone, S, Christensen, S.H, Read, R.J, Moriarty, N.W, Jensen, H.H, Deane, J.E.
Deposit date:2015-03-17
Release date:2015-03-25
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Azasugar Inhibitors as Pharmacological Chaperones for Krabbe Disease.
Chem.Sci., 6, 2015
4UFM
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BU of 4ufm by Molmil
Mouse Galactocerebrosidase complexed with 1-deoxy-galacto-nojirimycin DGJ
Descriptor: (2R,3S,4R,5S)-2-(hydroxymethyl)piperidine-3,4,5-triol, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Hill, C.H, Viuff, A.H, Spratley, S.J, Salamone, S, Christensen, S.H, Read, R.J, Moriarty, N.W, Jensen, H.H, Deane, J.E.
Deposit date:2015-03-17
Release date:2015-04-01
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Azasugar Inhibitors as Pharmacological Chaperones for Krabbe Disease.
Chem.Sci., 6, 2015
4UEX
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BU of 4uex by Molmil
Structure of human Saposin A at lysosomal pH
Descriptor: PROSAPOSIN
Authors:Hill, C.H, Read, R.J, Deane, J.E.
Deposit date:2014-12-20
Release date:2015-07-15
Last modified:2024-11-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structure of Human Saposin a at Lysosomal Ph.
Acta Crystallogr.,Sect.D, 71, 2015
1CZG
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BU of 1czg by Molmil
STRUCTURE OF THE G62T MUTANT OF SHIGA-LIKE TOXIN I B SUBUNIT
Descriptor: SHIGA TOXIN B-CHAIN
Authors:Ling, H, Bast, D, Brunton, J.L, Read, R.J.
Deposit date:1999-09-03
Release date:2000-09-13
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:STRUCTURE OF THE G62T MUTANT OF SHIGA-LIKE TOXIN I B SUBUNIT
To be Published
1CZW
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BU of 1czw by Molmil
STRUCTURE OF THE W34A MUTANT OF SHIGA-LIKE TOXIN I B SUBUNIT
Descriptor: SHIGA TOXIN B-CHAIN
Authors:Ling, H, Boodhoo, A, Brunton, J.L, Read, R.J.
Deposit date:1999-09-07
Release date:2000-09-08
Last modified:2018-03-14
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:A native structure of the W34A mutant at 2.5 A
To be Published

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