8TGJ
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![BU of 8tgj by Molmil](/molmil-images/mine/8tgj) | VMAT1 dimer in unbound form and with reserpine | Descriptor: | VMAT1 dimer in unbound form and with reserpine, reserpine | Authors: | Ye, J, Liu, B, Li, W. | Deposit date: | 2023-07-12 | Release date: | 2024-03-20 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Structural insights into vesicular monoamine storage and drug interactions. Nature, 629, 2024
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8TGK
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![BU of 8tgk by Molmil](/molmil-images/mine/8tgk) | VMAT1 dimer with histamine and reserpine | Descriptor: | Chromaffin granule amine transporter, HISTAMINE, reserpine | Authors: | Ye, J, Liu, B, Li, W. | Deposit date: | 2023-07-12 | Release date: | 2024-03-20 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | Structural insights into vesicular monoamine storage and drug interactions. Nature, 629, 2024
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6LR7
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![BU of 6lr7 by Molmil](/molmil-images/mine/6lr7) | |
6AEG
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![BU of 6aeg by Molmil](/molmil-images/mine/6aeg) | Crystal structure of xCas9 in complex with sgRNA and target DNA (GAT PAM) | Descriptor: | DNA (25-MER), DNA (5'-D(*AP*AP*AP*GP*AP*TP*TP*AP*TP*TP*G)-3'), DNA nuclease, ... | Authors: | Guo, M, Ren, K, Zhu, Y, Huang, Z. | Deposit date: | 2018-08-04 | Release date: | 2019-03-27 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.701 Å) | Cite: | Structural insights into a high fidelity variant of SpCas9. Cell Res., 29, 2019
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7DHJ
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![BU of 7dhj by Molmil](/molmil-images/mine/7dhj) | The co-crystal structure of SARS-CoV-2 main protease with the peptidomimetic inhibitor (S)-2-cinnamamido-N-((S)-1-oxo-3-((S)-2-oxopyrrolidin-3-yl)propan-2-yl)pent-4-ynamide | Descriptor: | (2~{S})-~{N}-[(2~{S})-1-oxidanylidene-3-[(3~{S})-2-oxidanylidenepyrrolidin-3-yl]propan-2-yl]-2-[[(~{E})-3-phenylprop-2-enoyl]amino]pent-4-ynamide, 3C-like proteinase | Authors: | Shang, L.Q, Wang, H, Deng, W.L, Xing, S, Wang, Y.X. | Deposit date: | 2020-11-15 | Release date: | 2021-11-24 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.962 Å) | Cite: | The structure-based design of peptidomimetic inhibitors against SARS-CoV-2 3C like protease as Potent anti-viral drug candidate. Eur.J.Med.Chem., 238, 2022
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6AEB
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![BU of 6aeb by Molmil](/molmil-images/mine/6aeb) | Crystal structure of xCas9 in complex with sgRNA and target DNA (AAG PAM) | Descriptor: | DNA (25-MER), DNA (5'-D(*AP*AP*AP*AP*AP*GP*TP*AP*TP*TP*G)-3'), DNA Nuclease, ... | Authors: | Guo, M, Ren, K, Zhu, Y, Huang, Z. | Deposit date: | 2018-08-04 | Release date: | 2019-03-27 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (3.004 Å) | Cite: | Structural insights into a high fidelity variant of SpCas9. Cell Res., 29, 2019
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3CLL
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![BU of 3cll by Molmil](/molmil-images/mine/3cll) | Crystal structure of the Spinach Aquaporin SoPIP2;1 S115E mutant | Descriptor: | Aquaporin | Authors: | Nyblom, M, Alfredsson, A, Hallgren, K, Hedfalk, K, Neutze, R, Trnroth-Horsefield, S. | Deposit date: | 2008-03-19 | Release date: | 2009-02-24 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structural and functional analysis of SoPIP2;1 mutants adds insight into plant aquaporin gating. J.Mol.Biol., 387, 2009
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8TWC
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![BU of 8twc by Molmil](/molmil-images/mine/8twc) | Acinetobacter phage AP205 T=3 VLP | Descriptor: | Coat protein | Authors: | Meng, R, Xing, Z, Zhang, J. | Deposit date: | 2023-08-20 | Release date: | 2024-03-06 | Last modified: | 2024-04-10 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Structural basis of Acinetobacter type IV pili targeting by an RNA virus. Nat Commun, 15, 2024
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8TVA
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![BU of 8tva by Molmil](/molmil-images/mine/8tva) | Outer Mat-T4P complex | Descriptor: | Fimbrial protein, Maturation protein | Authors: | Meng, R, Xing, Z, Thongchol, J, Zhang, J. | Deposit date: | 2023-08-17 | Release date: | 2024-03-06 | Last modified: | 2024-04-10 | Method: | ELECTRON MICROSCOPY (8.55 Å) | Cite: | Structural basis of Acinetobacter type IV pili targeting by an RNA virus. Nat Commun, 15, 2024
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8TV9
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![BU of 8tv9 by Molmil](/molmil-images/mine/8tv9) | Inner Mat-T4P complex | Descriptor: | Fimbrial protein, Maturation protein | Authors: | Meng, R, Xing, Z, Thongchol, J, Zhang, J. | Deposit date: | 2023-08-17 | Release date: | 2024-03-06 | Last modified: | 2024-04-10 | Method: | ELECTRON MICROSCOPY (8.15 Å) | Cite: | Structural basis of Acinetobacter type IV pili targeting by an RNA virus. Nat Commun, 15, 2024
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8TW2
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![BU of 8tw2 by Molmil](/molmil-images/mine/8tw2) | Acinetobacter phage AP205 T=4 VLP | Descriptor: | Coat protein | Authors: | Meng, R, Xing, Z, Zhang, J. | Deposit date: | 2023-08-19 | Release date: | 2024-03-06 | Last modified: | 2024-04-10 | Method: | ELECTRON MICROSCOPY (3.39 Å) | Cite: | Structural basis of Acinetobacter type IV pili targeting by an RNA virus. Nat Commun, 15, 2024
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3CN5
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![BU of 3cn5 by Molmil](/molmil-images/mine/3cn5) | Crystal structure of the Spinach Aquaporin SoPIP2;1 S115E, S274E mutant | Descriptor: | Aquaporin | Authors: | Nyblom, M, Alfredsson, A, Hallgren, K, Hedfalk, K, Neutze, R, Tornroth-Horsefield, S. | Deposit date: | 2008-03-25 | Release date: | 2009-02-24 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Structural and functional analysis of SoPIP2;1 mutants adds insight into plant aquaporin gating. J.Mol.Biol., 387, 2009
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8VF6
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![BU of 8vf6 by Molmil](/molmil-images/mine/8vf6) | Crystal structure of Serine/threonine-protein kinase 33 (STK33) Kinase Domain in complex with inhibitor CDD-2211 | Descriptor: | Serine/threonine-protein kinase 33, {3-[([1,1'-biphenyl]-2-yl)ethynyl]-1H-indazol-5-yl}[(3R)-3-(dimethylamino)pyrrolidin-1-yl]methanone | Authors: | Ta, H.M, Kim, C, Ku, K.A, Matzuk, M.M. | Deposit date: | 2023-12-21 | Release date: | 2024-06-05 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Reversible male contraception by targeted inhibition of serine/threonine kinase 33. Science, 384, 2024
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5VOV
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![BU of 5vov by Molmil](/molmil-images/mine/5vov) | Structure of AMPA receptor-TARP complex | Descriptor: | Glutamate receptor 2, Voltage-dependent calcium channel gamma-2 subunit | Authors: | Zhao, Y, Chen, S, Wang, Y.S, Shekhar, M, Tajkhorshid, E, Gouaux, E. | Deposit date: | 2017-05-03 | Release date: | 2017-07-12 | Last modified: | 2019-12-18 | Method: | ELECTRON MICROSCOPY (7.7 Å) | Cite: | Activation and Desensitization Mechanism of AMPA Receptor-TARP Complex by Cryo-EM. Cell, 170, 2017
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8WI0
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![BU of 8wi0 by Molmil](/molmil-images/mine/8wi0) | wt-hMRP5 inward-open | Descriptor: | ATP-binding cassette sub-family C member 5 | Authors: | Liu, Z.M, Huang, Y. | Deposit date: | 2023-09-24 | Release date: | 2024-07-03 | Method: | ELECTRON MICROSCOPY (2.93 Å) | Cite: | Inhibition and transport mechanisms of the ABC transporter hMRP5. Nat Commun, 15, 2024
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3FZK
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![BU of 3fzk by Molmil](/molmil-images/mine/3fzk) | Crystal Structures of Hsc70/Bag1 in Complex with Small Molecule Inhibitors | Descriptor: | (2R,3R,4S,5R)-2-[6-amino-8-[(3,4-dichlorophenyl)methylamino]purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diol, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, BAG family molecular chaperone regulator 1, ... | Authors: | Dokurno, P, Williamson, D.S, Murray, J.B, Surgenor, A.E. | Deposit date: | 2009-01-26 | Release date: | 2009-03-17 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Novel adenosine-derived inhibitors of 70 kDa heat shock protein, discovered through structure-based design J.Med.Chem., 52, 2009
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8WI5
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![BU of 8wi5 by Molmil](/molmil-images/mine/8wi5) | M5PI-bound hMRP5 | Descriptor: | ATP-binding cassette sub-family C member 5 | Authors: | Liu, Z.M, Huang, Y. | Deposit date: | 2023-09-24 | Release date: | 2024-07-03 | Method: | ELECTRON MICROSCOPY (3.46 Å) | Cite: | Inhibition and transport mechanisms of the ABC transporter hMRP5. Nat Commun, 15, 2024
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8WI2
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![BU of 8wi2 by Molmil](/molmil-images/mine/8wi2) | RD-hMRP5-inward open | Descriptor: | ATP-binding cassette sub-family C member 5, CYS-GLN-ASP-ALA-LEU-GLU-THR-ALA-ALA-ARG-ALA-GLU-GLY-LEU-SER-LEU-ASP-ALA-SER | Authors: | Liu, Z.M, Huang, Y. | Deposit date: | 2023-09-24 | Release date: | 2024-07-03 | Method: | ELECTRON MICROSCOPY (4.06 Å) | Cite: | Inhibition and transport mechanisms of the ABC transporter hMRP5. Nat Commun, 15, 2024
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8WI3
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![BU of 8wi3 by Molmil](/molmil-images/mine/8wi3) | ND-hMRP5-inward open | Descriptor: | ATP-binding cassette sub-family C member 5 | Authors: | Liu, Z.M, Huang, Y. | Deposit date: | 2023-09-24 | Release date: | 2024-07-03 | Method: | ELECTRON MICROSCOPY (3.38 Å) | Cite: | Inhibition and transport mechanisms of the ABC transporter hMRP5. Nat Commun, 15, 2024
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8WI4
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![BU of 8wi4 by Molmil](/molmil-images/mine/8wi4) | m6-hMRP5 inward open | Descriptor: | ATP-binding cassette sub-family C member 5 | Authors: | Liu, Z.M, Huang, Y. | Deposit date: | 2023-09-24 | Release date: | 2024-07-03 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Inhibition and transport mechanisms of the ABC transporter hMRP5. Nat Commun, 15, 2024
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3FZL
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![BU of 3fzl by Molmil](/molmil-images/mine/3fzl) | Crystal Structures of Hsc70/Bag1 in Complex with Small Molecule Inhibitors | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 4-[[(2R,3S,4R,5R)-5-[6-amino-8-[(3,4-dichlorophenyl)methylamino]purin-9-yl]-3,4-dihydroxy-oxolan-2-yl]methoxymethyl]benzonitrile, BAG family molecular chaperone regulator 1, ... | Authors: | Dokurno, P, Williamson, D.S, Murray, J.B, Surgenor, A.E. | Deposit date: | 2009-01-26 | Release date: | 2009-03-17 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Novel adenosine-derived inhibitors of 70 kDa heat shock protein, discovered through structure-based design J.Med.Chem., 52, 2009
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8X82
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![BU of 8x82 by Molmil](/molmil-images/mine/8x82) | |
8X83
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![BU of 8x83 by Molmil](/molmil-images/mine/8x83) | |
8X84
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![BU of 8x84 by Molmil](/molmil-images/mine/8x84) | |
3FZM
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![BU of 3fzm by Molmil](/molmil-images/mine/3fzm) | Crystal Structures of Hsc70/Bag1 in Complex with Small Molecule Inhibitors | Descriptor: | 4-[[(2R,3S,4R,5R)-5-[6-amino-8-(quinolin-6-ylmethylamino)purin-9-yl]-3,4-dihydroxy-oxolan-2-yl]methoxymethyl]benzonitri le, BAG family molecular chaperone regulator 1, Heat shock cognate 71 kDa protein | Authors: | Dokurno, P, Williamson, D.S, Murray, J.B, Surgenor, A.E. | Deposit date: | 2009-01-26 | Release date: | 2009-03-17 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Novel adenosine-derived inhibitors of 70 kDa heat shock protein, discovered through structure-based design J.Med.Chem., 52, 2009
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