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2WS6
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BU of 2ws6 by Molmil
Semi-synthetic analogue of human insulin NMeTyrB26-insulin in hexamer form
Descriptor: CHLORIDE ION, GLYCEROL, INSULIN A CHAIN, ...
Authors:Brzozowski, A.M, Jiracek, J, Zakova, L, Antolikova, E, Watson, C.J, Turkenburg, J.P, Dodson, G.G.
Deposit date:2009-09-03
Release date:2010-02-09
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Implications for the Active Form of Human Insulin Based on the Structural Convergence of Highly Active Hormone Analogues.
Proc.Natl.Acad.Sci.USA, 107, 2010
2WRV
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BU of 2wrv by Molmil
Semi-synthetic highly active analogue of human insulin NMeHisB26-DTI- NH2
Descriptor: ACETATE ION, INSULIN A CHAIN, INSULIN B CHAIN
Authors:Brzozowski, A.M, Jiracek, J, Zakova, L, Antolikova, E, Watson, C.J, Turkenburg, J.P, Dodson, G.G.
Deposit date:2009-09-02
Release date:2010-02-09
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Implications for the Active Form of Human Insulin Based on the Structural Convergence of Highly Active Hormone Analogues.
Proc.Natl.Acad.Sci.USA, 107, 2010
2WS4
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BU of 2ws4 by Molmil
Semi-synthetic analogue of human insulin ProB26-DTI in monomer form
Descriptor: INSULIN A CHAIN, INSULIN B CHAIN
Authors:Brzozowski, A.M, Jiracek, J, Zakova, L, Antolikova, E, Watson, C.J, Turkenburg, J.P, Dodson, G.G.
Deposit date:2009-09-03
Release date:2010-02-09
Last modified:2024-11-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Implications for the Active Form of Human Insulin Based on the Structural Convergence of Highly Active Hormone Analogues.
Proc.Natl.Acad.Sci.USA, 107, 2010
2WS0
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BU of 2ws0 by Molmil
Semi-synthetic analogue of human insulin NMeAlaB26-insulin at pH 7.5
Descriptor: INSULIN A CHAIN, INSULIN B CHAIN
Authors:Brzozowski, A.M, Jiracek, J, Zakova, L, Antolikova, E, Watson, C.J, Turkenburg, J.P, Dodson, G.G.
Deposit date:2009-09-03
Release date:2010-02-09
Last modified:2024-11-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Implications for the Active Form of Human Insulin Based on the Structural Convergence of Highly Active Hormone Analogues.
Proc.Natl.Acad.Sci.USA, 107, 2010
2X8R
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BU of 2x8r by Molmil
The structure of a family GH25 lysozyme from Aspergillus fumigatus
Descriptor: CHLORIDE ION, GLYCOSYL HYDROLASE
Authors:Korczynska, J.E, Danielsen, S, Schagerlof, U, Turkenburg, J.P, Davies, G.J, Wilson, K.S, Taylor, E.J.
Deposit date:2010-03-11
Release date:2010-09-08
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:The Structure of a Family Gh25 Lysozyme from Aspergillus Fumigatus
Acta Crystallogr.,Sect.F, 66, 2010
2YOY
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BU of 2yoy by Molmil
Bacillus amyloliquefaciens CBM33 in complex with Cu(I) reduced using ascorbate
Descriptor: 1,2-ETHANEDIOL, COPPER (I) ION, RBAM17540
Authors:Hemsworth, G.R, Taylor, E.J, Kim, R.Q, Lewis, S.J, Turkenburg, J.P, Davies, G.J, Walton, P.H.
Deposit date:2012-10-29
Release date:2013-04-10
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:The Copper Active Site of Cbm33 Polysaccharide Oxygenases.
J.Am.Chem.Soc., 135, 2013
3CTO
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BU of 3cto by Molmil
Crystal Structure of M. tuberculosis YefM antitoxin
Descriptor: SULFATE ION, Uncharacterized protein Rv3357/MT3465
Authors:Kumar, P, Issac, B, Dodson, E.J, Turkenberg, J.P, Mande, S.C.
Deposit date:2008-04-14
Release date:2008-12-02
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of Mycobacterium tuberculosis YefM antitoxin reveals that it is not an intrinsically unstructured protein
J.Mol.Biol., 383, 2008
8ROZ
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BU of 8roz by Molmil
Cryo-EM structure of CDK2-cyclin A in complex with CDC25A
Descriptor: Cyclin-A2, Cyclin-dependent kinase 2, M-phase inducer phosphatase 1
Authors:Rowland, R.J, Noble, M.E.M, Endicott, J.A.
Deposit date:2024-01-12
Release date:2024-05-29
Last modified:2024-11-13
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:Cryo-EM structure of the CDK2-cyclin A-CDC25A complex.
Nat Commun, 15, 2024
5LWH
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BU of 5lwh by Molmil
CeuE (Y288F variant) a periplasmic protein from Campylobacter jejuni.
Descriptor: Enterochelin ABC transporter substrate-binding protein, ZINC ION
Authors:Wilde, E.J, Blagova, E, Hughes, A, Raines, D.J, Moroz, O.V, Turkenburg, J, Duhme-Klair, A.-K, Wilson, K.S.
Deposit date:2016-09-16
Release date:2017-04-12
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.47 Å)
Cite:Interactions of the periplasmic binding protein CeuE with Fe(III) n-LICAM(4-) siderophore analogues of varied linker length.
Sci Rep, 7, 2017
2V4C
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BU of 2v4c by Molmil
Structure of sialic acid binding protein (SiaP) in the presence of KDN
Descriptor: SIALIC ACID-BINDING PERIPLASMIC PROTEIN SIAP, deamino-beta-neuraminic acid
Authors:Fischer, M, Hubbard, R.E.
Deposit date:2008-09-18
Release date:2010-03-31
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Water networks can determine the affinity of ligand binding to proteins.
J.Am.Chem.Soc., 2019
4TGL
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BU of 4tgl by Molmil
CATALYSIS AT THE INTERFACE: THE ANATOMY OF A CONFORMATIONAL CHANGE IN A TRIGLYCERIDE LIPASE
Descriptor: DIETHYL PHOSPHONATE, TRIACYL-GLYCEROL ACYLHYDROLASE
Authors:Derewenda, U, Brzozowski, A.M, Lawson, D, Derewenda, Z.S.
Deposit date:1991-07-29
Release date:1993-07-15
Last modified:2024-11-20
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Catalysis at the interface: the anatomy of a conformational change in a triglyceride lipase.
Biochemistry, 31, 1992
6TSB
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BU of 6tsb by Molmil
Crystal structure of the Chitinase Domain of the Spore Coat Protein CotE from Clostridium difficile
Descriptor: DI(HYDROXYETHYL)ETHER, Peroxiredoxin
Authors:Whittingham, J.L, Dodson, E.J, Wilkinson, A.J.
Deposit date:2019-12-20
Release date:2020-06-24
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structures of the GH18 domain of the bifunctional peroxiredoxin-chitinase CotE from Clostridium difficile.
Acta Crystallogr.,Sect.F, 76, 2020
6Y5S
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BU of 6y5s by Molmil
Crystal structure of savinase at cryogenic conditions
Descriptor: CALCIUM ION, SODIUM ION, Subtilisin Savinase
Authors:Wu, S, Moroz, O, Turkenburg, J, Nielsen, J.E, Wilson, K.S, Teilum, K.
Deposit date:2020-02-25
Release date:2020-06-17
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (0.95 Å)
Cite:Conformational heterogeneity of Savinase from NMR, HDX-MS and X-ray diffraction analysis.
Peerj, 8, 2020
6Y5T
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BU of 6y5t by Molmil
Crystal structure of savinase at room temperature
Descriptor: CALCIUM ION, SODIUM ION, Subtilisin Savinase
Authors:Wu, S, Moroz, O, Turkenburg, J, Nielsen, J.E, Wilson, K.S, Teilum, K.
Deposit date:2020-02-25
Release date:2020-06-17
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.1 Å)
Cite:Conformational heterogeneity of Savinase from NMR, HDX-MS and X-ray diffraction analysis.
Peerj, 8, 2020
8ARN
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BU of 8arn by Molmil
Crystal structure of the peptide binding protein, OppA, from Bacillus subtilis in complex with an endogenous tetrapeptide
Descriptor: Endogenous tetrapeptide (SER-ASN-SER-SER), Oligopeptide-binding protein OppA
Authors:Hughes, A, Dodson, E.J, Wilkinson, A.J.
Deposit date:2022-08-17
Release date:2023-02-22
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Peptide transport in Bacillus subtilis - structure and specificity in the extracellular solute binding proteins OppA and DppE.
Microbiology (Reading, Engl.), 168, 2022
8ARE
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BU of 8are by Molmil
Crystal structure of the peptide binding protein, OppA, from Bacillus subtilis in complex with a PhrE-derived pentapeptide
Descriptor: Oligopeptide-binding protein OppA, Phosphatase RapE inhibitor, SULFATE ION
Authors:Hughes, A, Dodson, E.J, Wilkinson, A.J.
Deposit date:2022-08-16
Release date:2023-02-22
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Peptide transport in Bacillus subtilis - structure and specificity in the extracellular solute binding proteins OppA and DppE.
Microbiology (Reading, Engl.), 168, 2022
8AM3
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BU of 8am3 by Molmil
Cyclohexanone dehydrogenase (CDH) from Alicycliphilus denitrificans K601 - wildtype
Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, Fumarate reductase/succinate dehydrogenase flavoprotein domain protein, GLYCEROL, ...
Authors:Prior, S.H, Taylor, E.J.
Deposit date:2022-08-02
Release date:2024-02-14
Last modified:2024-04-10
Method:X-RAY DIFFRACTION (1.86 Å)
Cite:Rational design of a cyclohexanone dehydrogenase for enhanced alpha , beta-desaturation and substrate specificity.
Chem Sci, 15, 2024
8AM8
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BU of 8am8 by Molmil
Cyclohexanone dehydrogenase (CDH) from Alicycliphilus denitrificans K601 complexed with dehydrogenated substrate - W113A mutant
Descriptor: DI(HYDROXYETHYL)ETHER, FLAVIN-ADENINE DINUCLEOTIDE, Fumarate reductase/succinate dehydrogenase flavoprotein domain protein, ...
Authors:Prior, S.H, Taylor, E.J.
Deposit date:2022-08-03
Release date:2024-02-14
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Rational design of a cyclohexanone dehydrogenase for enhanced alpha , beta-desaturation and substrate specificity.
Chem Sci, 15, 2024
8AM6
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BU of 8am6 by Molmil
Cyclohexanone dehydrogenase (CDH) from Alicycliphilus denitrificans K601 complexed with dehydrogenated substrate cyclohex-2-en-1-one - inactive mutant (Y195F)
Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, Fumarate reductase/succinate dehydrogenase flavoprotein domain protein, GLYCEROL, ...
Authors:Prior, S.H, Taylor, E.J.
Deposit date:2022-08-02
Release date:2024-02-14
Last modified:2024-11-20
Method:X-RAY DIFFRACTION (1.33 Å)
Cite:Rational design of a cyclohexanone dehydrogenase for enhanced alpha , beta-desaturation and substrate specificity.
Chem Sci, 15, 2024
8AY0
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BU of 8ay0 by Molmil
Crystal Structure of the peptide binding protein DppE from Bacillus subtilis in complex with murein tripeptide
Descriptor: 1,2-ETHANEDIOL, Dipeptide-binding protein DppE, L-ALA-GAMMA-D-GLU-MESO-DIAMINOPIMELIC ACID, ...
Authors:Hughes, A.M, Dodson, E.J, Wilkinson, A.J.
Deposit date:2022-09-01
Release date:2023-02-22
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.51 Å)
Cite:Peptide transport in Bacillus subtilis - structure and specificity in the extracellular solute binding proteins OppA and DppE.
Microbiology (Reading, Engl.), 168, 2022
8AZB
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BU of 8azb by Molmil
Crystal Structure of the peptide binding protein DppE from Bacillus subtilis in the unliganded state
Descriptor: Dipeptide-binding protein DppE
Authors:Hughes, A.M, Dodson, E.J, Wilkinson, A.J.
Deposit date:2022-09-05
Release date:2023-02-22
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Peptide transport in Bacillus subtilis - structure and specificity in the extracellular solute binding proteins OppA and DppE.
Microbiology (Reading, Engl.), 168, 2022
6IAQ
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BU of 6iaq by Molmil
Structure of Amine Dehydrogenase from Mycobacterium smegmatis
Descriptor: 1,2-ETHANEDIOL, Dihydrodipicolinate reductase N-terminus domain-containing protein, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Grogan, G, Vaxelaire-Vergne, C, Beloti, L, Mayol, O.
Deposit date:2018-11-27
Release date:2019-03-27
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.91 Å)
Cite:A family of native amine dehydrogenases for the asymmetric reductive amination of ketones
Nat Catal, 2019
6I3G
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BU of 6i3g by Molmil
Crystal structure of a putative peptide binding protein AppA from Clostridium difficile
Descriptor: ABC transporter, substrate-binding protein, family 5, ...
Authors:Hughes, A.M, Wilkinson, A, Dodson, E.
Deposit date:2018-11-06
Release date:2019-04-10
Last modified:2024-05-15
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of the putative peptide-binding protein AppA from Clostridium difficile.
Acta Crystallogr.,Sect.F, 75, 2019
9GYY
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BU of 9gyy by Molmil
Crystal structure of domain-of-unknown-function DUF4867 from Bacillus megaterium
Descriptor: CHLORIDE ION, DUF4867 domain-containing protein, FE (III) ION, ...
Authors:Sharma, M, Davies, G.J.
Deposit date:2024-10-03
Release date:2025-02-26
Last modified:2025-04-02
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Sulfoglycolysis sustains Eubacterium rectale in low-fiber diets.
J.Biol.Chem., 301, 2025
9GYZ
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BU of 9gyz by Molmil
Crystal structure of domain-of-unknown-function DUF4867 from Bacillus megaterium (unmodelled additional ligand density at active site)
Descriptor: DUF4867 domain-containing protein, FE (III) ION
Authors:Sharma, M, Davies, G.J.
Deposit date:2024-10-03
Release date:2025-02-26
Last modified:2025-04-02
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Sulfoglycolysis sustains Eubacterium rectale in low-fiber diets.
J.Biol.Chem., 301, 2025

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