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3BM1
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BU of 3bm1 by Molmil
Crystal structure of a minimal nitroreductase ydjA from Escherichia coli K12 with and without FMN cofactor
Descriptor: FLAVIN MONONUCLEOTIDE, Protein ydjA
Authors:Choi, J.W, Kim, J.S.
Deposit date:2007-12-12
Release date:2008-01-01
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of a minimal nitroreductase, ydjA, from Escherichia coli K12 with and without FMN cofactor
J.Mol.Biol., 377, 2008
8RKH
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BU of 8rkh by Molmil
Crystal structure of the ZP-N2 and ZP-N3 domains of mouse ZP2 (mZP2-N2N3)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Zona pellucida sperm-binding protein 2, ...
Authors:Fahrenkamp, D, de Sanctis, D, Jovine, L.
Deposit date:2023-12-25
Release date:2024-03-13
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:ZP2 cleavage blocks polyspermy by modulating the architecture of the egg coat.
Cell, 187, 2024
8RKE
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BU of 8rke by Molmil
Crystal structure of the complete N-terminal region of human ZP2 (hZP2-N1N2N3)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Zona pellucida sperm-binding protein 2, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Fahrenkamp, D, de Sanctis, D, Jovine, L.
Deposit date:2023-12-25
Release date:2024-03-13
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:ZP2 cleavage blocks polyspermy by modulating the architecture of the egg coat.
Cell, 187, 2024
8RKF
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BU of 8rkf by Molmil
Crystal structure of the ZP-N1 and ZP-N2 domains of human ZP2 (hZP2-N1N2)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Zona pellucida sperm-binding protein 2
Authors:Dioguardi, E, Stsiapanava, A, de Sanctis, D, Jovine, L.
Deposit date:2023-12-25
Release date:2024-03-13
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:ZP2 cleavage blocks polyspermy by modulating the architecture of the egg coat.
Cell, 187, 2024
7PFP
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BU of 7pfp by Molmil
Full-length cryo-EM structure of the native human uromodulin (UMOD)/Tamm-Horsfall protein (THP) filament
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Uromodulin, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Jovine, L, Xu, C, Stsiapanava, A, Carroni, M, Tunyasuvunakool, K, Jumper, J, Wu, B.
Deposit date:2021-08-11
Release date:2022-03-16
Last modified:2022-03-30
Method:ELECTRON MICROSCOPY (6.1 Å)
Cite:Structure of the decoy module of human glycoprotein 2 and uromodulin and its interaction with bacterial adhesin FimH.
Nat.Struct.Mol.Biol., 29, 2022
6L8A
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BU of 6l8a by Molmil
Tetrathionate hydrolase from Acidithiobacillus ferrooxidans
Descriptor: BETA-ALANINE, GLYCINE, SULFATE ION, ...
Authors:Tamada, T, Hirano, Y.
Deposit date:2019-11-05
Release date:2020-11-11
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (1.95004809 Å)
Cite:Reaction mechanism of tetrathionate hydrolysis based on the crystal structure of tetrathionate hydrolase from Acidithiobacillus ferrooxidans.
Protein Sci., 30, 2020
8W6X
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BU of 8w6x by Molmil
Neutron structure of [NiFe]-hydrogenase from D. vulgaris Miyazaki F in its oxidized state
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, CHLORIDE ION, FE3-S4 CLUSTER, ...
Authors:Hiromoto, T, Tamada, T.
Deposit date:2023-08-30
Release date:2023-09-13
Last modified:2023-11-15
Method:NEUTRON DIFFRACTION (1.04 Å), X-RAY DIFFRACTION
Cite:New insights into the oxidation process from neutron and X-ray crystal structures of an O 2 -sensitive [NiFe]-hydrogenase.
Chem Sci, 14, 2023
1RKR
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BU of 1rkr by Molmil
CRYSTAL STRUCTURE OF AZURIN-I FROM ALCALIGENES XYLOSOXIDANS NCIMB 11015
Descriptor: AZURIN-I, COPPER (II) ION
Authors:Li, C, Inoue, T, Gotowda, M, Suzuki, S, Yamaguchi, K, Kataoka, K, Kai, Y.
Deposit date:1997-05-17
Release date:1998-05-20
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Structure of azurin I from the denitrifying bacterium Alcaligenes xylosoxidans NCIMB 11015 at 2.45 A resolution.
Acta Crystallogr.,Sect.D, 54, 1998
8T8A
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BU of 8t8a by Molmil
Structure of arginine oxidase from Pseudomonas sp. TRU 7192
Descriptor: Amine oxidoreductase, FLAVIN-ADENINE DINUCLEOTIDE
Authors:Takahashi, K, Yamaguchi, H, Tatsumi, M, Sugiki, M.
Deposit date:2023-06-22
Release date:2024-06-26
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Structural basis of arginine oxidase from Pseudomonas sp. TRU 7192
To Be Published
6T9C
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BU of 6t9c by Molmil
Crystal structure of the complex between PPARgamma LBD and the ligand NV1346 (3a)
Descriptor: 4-hexoxy-~{N}-[(2~{S})-3-methyl-1-(oxidanylamino)-1-oxidanylidene-butan-2-yl]benzamide, Peroxisome proliferator-activated receptor gamma
Authors:Pochetti, G, Montanari, R, Capelli, D.
Deposit date:2019-10-27
Release date:2020-02-26
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Insights into PPAR gamma Phosphorylation and Its Inhibition Mechanism.
J.Med.Chem., 63, 2020
1RRP
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BU of 1rrp by Molmil
STRUCTURE OF THE RAN-GPPNHP-RANBD1 COMPLEX
Descriptor: MAGNESIUM ION, NUCLEAR PORE COMPLEX PROTEIN NUP358, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ...
Authors:Vetter, I.R, Nowak, C, Nishimoto, T, Kuhlmann, J, Wittinghofer, A.
Deposit date:1999-01-15
Release date:1999-05-18
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.96 Å)
Cite:Structure of a Ran-binding domain complexed with Ran bound to a GTP analogue: implications for nuclear transport.
Nature, 398, 1999
6L93
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BU of 6l93 by Molmil
X-ray structure of the ligand-free human TRPV1 ankyrin repeat domain
Descriptor: Transient receptor potential cation channel subfamily V member 1
Authors:Tanaka, M, Hayakawa, K, Unno, M.
Deposit date:2019-11-08
Release date:2020-03-18
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (4.47 Å)
Cite:Structure determination of the human TRPV1 ankyrin-repeat domain under nonreducing conditions.
Acta Crystallogr.,Sect.F, 76, 2020
4WRN
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BU of 4wrn by Molmil
Crystal structure of the polymerization region of human uromodulin/Tamm-Horsfall protein
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Maltose-binding periplasmic protein,Uromodulin, ZINC ION, ...
Authors:Bokhove, M, De Sanctis, D, Jovine, L.
Deposit date:2014-10-24
Release date:2016-01-27
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:A structured interdomain linker directs self-polymerization of human uromodulin.
Proc.Natl.Acad.Sci.USA, 113, 2016
4XIG
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BU of 4xig by Molmil
Crystal structure of bacterial alginate ABC transporter determined through humid air and glue-coating method
Descriptor: 4-deoxy-alpha-L-erythro-hex-4-enopyranuronic acid-(1-4)-beta-D-mannopyranuronic acid-(1-4)-beta-D-mannopyranuronic acid-(1-4)-beta-D-mannopyranuronic acid, AlgM1, AlgM2, ...
Authors:Kaneko, A, Maruyama, Y, Mizuno, N, Baba, S, Kumasaka, T, Mikami, B, Murata, K, Hashimoto, W.
Deposit date:2015-01-07
Release date:2016-01-13
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (3.402 Å)
Cite:A solute-binding protein in the closed conformation induces ATP hydrolysis in a bacterial ATP-binding cassette transporter involved in the import of alginate.
J.Biol.Chem., 292, 2017
8IF4
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BU of 8if4 by Molmil
Structure of human alpha-2/delta-1 without mirogabalin
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Voltage-dependent calcium channel subunit alpha-2/delta-1
Authors:Kozai, D, Numoto, N, Fujiyoshi, Y.
Deposit date:2023-02-17
Release date:2023-04-05
Last modified:2023-04-12
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Recognition Mechanism of a Novel Gabapentinoid Drug, Mirogabalin, for Recombinant Human alpha 2 delta 1, a Voltage-Gated Calcium Channel Subunit.
J.Mol.Biol., 435, 2023
8IF3
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BU of 8if3 by Molmil
Structure of human alpha-2/delta-1 with mirogabalin
Descriptor: 2-[(1R,5S,6S)-6-(aminomethyl)-3-ethyl-6-bicyclo[3.2.0]hept-3-enyl]acetic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Kozai, D, Numoto, N, Fujiyoshi, Y.
Deposit date:2023-02-17
Release date:2023-04-05
Last modified:2023-04-12
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Recognition Mechanism of a Novel Gabapentinoid Drug, Mirogabalin, for Recombinant Human alpha 2 delta 1, a Voltage-Gated Calcium Channel Subunit.
J.Mol.Biol., 435, 2023
4XTC
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BU of 4xtc by Molmil
Crystal structure of bacterial alginate ABC transporter in complex with alginate pentasaccharide-bound periplasmic protein
Descriptor: AlgM1, AlgM2, AlgQ2, ...
Authors:Kaneko, A, Maruyama, Y, Mizuno, N, Baba, S, Kumasaka, T, Mikami, B, Murata, K, Hashimoto, W.
Deposit date:2015-01-23
Release date:2016-03-02
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:A solute-binding protein in the closed conformation induces ATP hydrolysis in a bacterial ATP-binding cassette transporter involved in the import of alginate.
J.Biol.Chem., 292, 2017
5B36
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BU of 5b36 by Molmil
Crystal Structure of the O-Phosphoserine Sulfhydrylase from Aeropyrum pernix Complexed with Cysteine
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, CYSTEINE, PYRIDOXAL-5'-PHOSPHATE, ...
Authors:Nakamura, T, Takeda, E, Kawai, Y, Kataoka, M, Ishikawa, K.
Deposit date:2016-02-10
Release date:2016-03-16
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Role of F225 in O-phosphoserine sulfhydrylase from Aeropyrum pernix K1
Extremophiles, 20, 2016
5B3A
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BU of 5b3a by Molmil
Crystal Structure of O-Phoshoserine Sulfhydrylase from Aeropyrum pernix in Complexed with the alpha-Aminoacrylate Intermediate
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, 2-{[(E)-{3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methylidene]amino}prop-2-enoic acid, Protein CysO
Authors:Nakamura, T, Takeda, E, Kawai, Y, Kataoka, M, Ishikawa, K.
Deposit date:2016-02-12
Release date:2016-03-16
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.14 Å)
Cite:Role of F225 in O-phosphoserine sulfhydrylase from Aeropyrum pernix K1
Extremophiles, 20, 2016
1G0D
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BU of 1g0d by Molmil
CRYSTAL STRUCTURE OF RED SEA BREAM TRANSGLUTAMINASE
Descriptor: PROTEIN-GLUTAMINE GAMMA-GLUTAMYLTRANSFERASE, SULFATE ION
Authors:Noguchi, K, Ishikawa, K, Yokoyama, K, Ohtsuka, T, Nio, N, Suzuki, E.
Deposit date:2000-10-06
Release date:2001-05-23
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of red sea bream transglutaminase.
J.Biol.Chem., 276, 2001
6AKF
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BU of 6akf by Molmil
Crystal structure of mouse claudin-3 P134A mutant in complex with C-terminal fragment of Clostridium perfringens enterotoxin
Descriptor: Claudin-3, Heat-labile enterotoxin B chain
Authors:Nakamura, S, Irie, K, Fujiyoshi, Y.
Deposit date:2018-08-31
Release date:2019-02-20
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (3.9 Å)
Cite:Morphologic determinant of tight junctions revealed by claudin-3 structures.
Nat Commun, 10, 2019
6AKG
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BU of 6akg by Molmil
Crystal structure of mouse claudin-3 P134G mutant in complex with C-terminal fragment of Clostridium perfringens enterotoxin
Descriptor: Claudin-3, Heat-labile enterotoxin B chain
Authors:Nakamura, S, Irie, K, Fujiyoshi, Y.
Deposit date:2018-08-31
Release date:2019-02-20
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (4.3 Å)
Cite:Morphologic determinant of tight junctions revealed by claudin-3 structures.
Nat Commun, 10, 2019
6AKE
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BU of 6ake by Molmil
Crystal structure of mouse claudin-3 in complex with C-terminal fragment of Clostridium perfringens enterotoxin
Descriptor: Claudin-3, Heat-labile enterotoxin B chain
Authors:Nakamura, S, Irie, K, Fujiyoshi, Y.
Deposit date:2018-08-31
Release date:2019-02-27
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:Morphologic determinant of tight junctions revealed by claudin-3 structures.
Nat Commun, 10, 2019
6ZLY
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BU of 6zly by Molmil
Crystal structure of the complex between PPARgamma LBD and the ligand NV1362 (7a)
Descriptor: (2~{S})-2-[(4-hexoxyphenyl)carbonylamino]-3-methyl-butanoic acid, Peroxisome proliferator-activated receptor gamma
Authors:Pochetti, G, Montanari, R, Capelli, D.
Deposit date:2020-07-01
Release date:2020-11-25
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.79 Å)
Cite:A Novel N-Substituted Valine Derivative with Unique Peroxisome Proliferator-Activated Receptor gamma Binding Properties and Biological Activities.
J.Med.Chem., 63, 2020
7WDT
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BU of 7wdt by Molmil
6-sulfo-beta-D-N-acetylglucosaminidase from Bifidobacterium bifidum in complex with GlcNAc-6S
Descriptor: 2-acetamido-2-deoxy-6-O-sulfo-alpha-D-glucopyranose, 2-acetamido-2-deoxy-6-O-sulfo-beta-D-glucopyranose, Beta-N-acetylhexosaminidase, ...
Authors:Yamada, C, Kashima, T, Fushinobu, S, Katoh, T, Katayama, T.
Deposit date:2021-12-22
Release date:2022-12-28
Last modified:2023-06-14
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:A bacterial sulfoglycosidase highlights mucin O-glycan breakdown in the gut ecosystem.
Nat.Chem.Biol., 19, 2023

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