3H0V
| Human AdoMetDC with 5'-Deoxy-5'-(dimethylsulfonio) adenosine | Descriptor: | 1,4-DIAMINOBUTANE, 5'-deoxy-5'-(dimethyl-lambda~4~-sulfanyl)adenosine, PYRUVIC ACID, ... | Authors: | Bale, S, Brooks, W.H, Hanes, J.W, Mahesan, A.M, Guida, W.C, Ealick, S.E. | Deposit date: | 2009-04-10 | Release date: | 2009-06-30 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.24 Å) | Cite: | Role of the sulfonium center in determining the ligand specificity of human s-adenosylmethionine decarboxylase. Biochemistry, 48, 2009
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3GMC
| Crystal Structure of 2-Methyl-3-hydroxypyridine-5-carboxylic acid Oxygenase with substrate bound | Descriptor: | 2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenase, 5-hydroxy-6-methylpyridine-3-carboxylic acid, FLAVIN-ADENINE DINUCLEOTIDE | Authors: | McCulloch, K.M, Mukherjee, T, Begley, T.P, Ealick, S.E. | Deposit date: | 2009-03-13 | Release date: | 2009-04-14 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structure of the PLP degradative enzyme 2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenase from Mesorhizobium loti MAFF303099 and its mechanistic implications. Biochemistry, 48, 2009
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3GMB
| Crystal Structure of 2-Methyl-3-hydroxypyridine-5-carboxylic acid Oxygenase | Descriptor: | 2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenase, FLAVIN-ADENINE DINUCLEOTIDE | Authors: | McCulloch, K.M, Mukherjee, T, Begley, T.P, Ealick, S.E. | Deposit date: | 2009-03-13 | Release date: | 2009-04-14 | Last modified: | 2017-11-01 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structure of the PLP degradative enzyme 2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenase from Mesorhizobium loti MAFF303099 and its mechanistic implications. Biochemistry, 48, 2009
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3RP7
| Crystal Structure of Klebsiella pneumoniae HpxO complexed with FAD and uric acid | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, URIC ACID, flavoprotein monooxygenase | Authors: | Hicks, K.A, O'Leary, S.E, Begley, T.P, Ealick, S.E. | Deposit date: | 2011-04-26 | Release date: | 2012-05-16 | Last modified: | 2013-02-06 | Method: | X-RAY DIFFRACTION (2.042 Å) | Cite: | Structural and Mechanistic Studies of HpxO, a Novel Flavin Adenine Dinucleotide-Dependent Urate Oxidase from Klebsiella pneumoniae. Biochemistry, 52, 2013
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3RP8
| Crystal Structure of Klebsiella pneumoniae R204Q HpxO complexed with FAD | Descriptor: | CHLORIDE ION, FLAVIN-ADENINE DINUCLEOTIDE, flavoprotein monooxygenase | Authors: | Hicks, K.A, O'Leary, S.E, Begley, T.P, Ealick, S.E. | Deposit date: | 2011-04-26 | Release date: | 2012-05-16 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.968 Å) | Cite: | Structural and Mechanistic Studies of HpxO, a Novel Flavin Adenine Dinucleotide-Dependent Urate Oxidase from Klebsiella pneumoniae. Biochemistry, 52, 2013
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3IX1
| Periplasmic N-formyl-4-amino-5-aminomethyl-2-methylpyrimidine binding protein from Bacillus halodurans | Descriptor: | N-[(4-amino-2-methylpyrimidin-5-yl)methyl]formamide, N-formyl-4-amino-5-aminomethyl-2-methylpyrimidine binding protein | Authors: | Bale, S, Rajashankar, K.R, Perry, K, Begley, T.P, Ealick, S.E. | Deposit date: | 2009-09-03 | Release date: | 2010-10-13 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | HMP Binding Protein ThiY and HMP-P Synthase THI5 Are Structural Homologues. Biochemistry, 49, 2010
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3JSK
| Thiazole synthase from Neurospora crassa | Descriptor: | ADENOSINE DIPHOSPHATE 5-(BETA-ETHYL)-4-METHYL-THIAZOLE-2-CARBOXYLIC ACID, CyPBP37 protein, FE (II) ION | Authors: | Kang, Y.N, Bale, S, Ealick, S.E. | Deposit date: | 2009-09-10 | Release date: | 2010-09-29 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Crystal structure of thiazole synthase Thi4 from Neurospora crassa to be published
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3RP6
| Crystal Structure of Klebsiella pneumoniae HpxO complexed with FAD | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, flavoprotein monooxygenase | Authors: | Hicks, K.A, O'Leary, S.E, Begley, T.P, Ealick, S.E. | Deposit date: | 2011-04-26 | Release date: | 2012-05-16 | Last modified: | 2013-02-06 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structural and Mechanistic Studies of HpxO, a Novel Flavin Adenine Dinucleotide-Dependent Urate Oxidase from Klebsiella pneumoniae. Biochemistry, 52, 2013
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3HQB
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3HQA
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3IWD
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3IWC
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3IWB
| T. maritima AdoMetDC in processed form | Descriptor: | S-adenosylmethionine decarboxylase | Authors: | Bale, S, Kavita, B, Ealick, S.E. | Deposit date: | 2009-09-02 | Release date: | 2010-02-09 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.06 Å) | Cite: | Complexes of Thermotoga maritimaS-adenosylmethionine decarboxylase provide insights into substrate specificity. Acta Crystallogr.,Sect.D, 66, 2010
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3FPZ
| Saccharomyces cerevisiae THI4p is a suicide thiamin thiazole synthase | Descriptor: | ADENOSINE DIPHOSPHATE 5-(BETA-ETHYL)-4-METHYL-THIAZOLE-2-CARBOXYLIC ACID, SULFATE ION, Thiazole biosynthetic enzyme | Authors: | Bale, S, Chatterjee, A, Dorrestein, P.C, Begley, T.P, Ealick, S.E. | Deposit date: | 2009-01-06 | Release date: | 2010-01-19 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.82 Å) | Cite: | Saccharomyces cerevisiae THI4p is a suicide thiamine thiazole synthase. Nature, 478, 2011
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1JDU
| CRYSTAL STRUCTURE OF 5'-DEOXY-5'-METHYLTHIOADENOSINE PHOSPHORYLASE | Descriptor: | 5'-METHYLTHIOADENOSINE PHOSPHORYLASE | Authors: | Appleby, T.C, Mathews, I.I, Porcelli, M, Cacciapuoti, G, Ealick, S.E. | Deposit date: | 2001-06-15 | Release date: | 2001-10-26 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Three-dimensional structure of a hyperthermophilic 5'-deoxy-5'-methylthioadenosine phosphorylase from Sulfolobus solfataricus. J.Biol.Chem., 276, 2001
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1JDZ
| CRYSTAL STRUCTURE OF 5'-DEOXY-5'-METHYLTHIOADENOSINE PHOSPHORYLASE WITH FORMYCIN B AND SULFATE ION | Descriptor: | 5'-METHYLTHIOADENOSINE PHOSPHORYLASE, FORMYCIN B, SULFATE ION | Authors: | Appleby, T.C, Mathews, I.I, Porcelli, M, Cacciapuoti, G, Ealick, S.E. | Deposit date: | 2001-06-15 | Release date: | 2001-10-26 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Three-dimensional structure of a hyperthermophilic 5'-deoxy-5'-methylthioadenosine phosphorylase from Sulfolobus solfataricus. J.Biol.Chem., 276, 2001
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1JE0
| CRYSTAL STRUCTURE OF 5'-DEOXY-5'-METHYLTHIOADENOSINE PHOSPHORYLASE COMPLEXED WITH PHOSPHATE AND TRIS MOLECULE | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 5'-METHYLTHIOADENOSINE PHOSPHORYLASE, PHOSPHATE ION | Authors: | Appleby, T.C, Mathews, I.I, Porcelli, M, Cacciapuoti, G, Ealick, S.E. | Deposit date: | 2001-06-15 | Release date: | 2001-10-26 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Three-dimensional structure of a hyperthermophilic 5'-deoxy-5'-methylthioadenosine phosphorylase from Sulfolobus solfataricus. J.Biol.Chem., 276, 2001
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3T94
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1JP7
| Crystal Structure of 5'-deoxy-5'-methylthioadenosine phosphorylase | Descriptor: | 5'-deoxy-5'-methylthioadenosine phosphorylase, SULFATE ION | Authors: | Appleby, T.C, Mathews, I.I, Porcelli, M, Cacciapuoti, G, Ealick, S.E. | Deposit date: | 2001-08-01 | Release date: | 2001-10-26 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Three-dimensional structure of a hyperthermophilic 5'-deoxy-5'-methylthioadenosine phosphorylase from Sulfolobus solfataricus. J.Biol.Chem., 276, 2001
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1JPV
| Crystal Structure of 5'-deoxy-5'-methylthioadenosine phosphorylase complexed with SO4 | Descriptor: | 5'-deoxy-5'-methylthioadenosine phosphorylase, SULFATE ION | Authors: | Appleby, T.C, Mathews, I.I, Porcelli, M, Cacciapuoti, G, Ealick, S.E. | Deposit date: | 2001-08-03 | Release date: | 2001-10-26 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Three-dimensional structure of a hyperthermophilic 5'-deoxy-5'-methylthioadenosine phosphorylase from Sulfolobus solfataricus. J.Biol.Chem., 276, 2001
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1JDV
| CRYSTAL STRUCTURE OF 5'-DEOXY-5'-METHYLTHIOADENOSINE PHOSPHORYLASE COMPLEXED WITH ADENOSINE AND SULFATE ION | Descriptor: | 5'-METHYLTHIOADENOSINE PHOSPHORYLASE, ADENOSINE, SULFATE ION | Authors: | Appleby, T.C, Mathews, I.I, Porcelli, M, Cacciapuoti, G, Ealick, S.E. | Deposit date: | 2001-06-15 | Release date: | 2001-10-26 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Three-dimensional structure of a hyperthermophilic 5'-deoxy-5'-methylthioadenosine phosphorylase from Sulfolobus solfataricus. J.Biol.Chem., 276, 2001
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1JDS
| 5'-DEOXY-5'-METHYLTHIOADENOSINE PHOSPHORYLASE COMPLEX WITH PHOSPHATE (SPACE GROUP P21) | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 5'-METHYLTHIOADENOSINE PHOSPHORYLASE, PHOSPHATE ION | Authors: | Appleby, T.C, Mathews, I.I, Porcelli, M, Cacciapuoti, G, Ealick, S.E. | Deposit date: | 2001-06-15 | Release date: | 2001-10-26 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Three-dimensional structure of a hyperthermophilic 5'-deoxy-5'-methylthioadenosine phosphorylase from Sulfolobus solfataricus. J.Biol.Chem., 276, 2001
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1JDT
| CRYSTAL STRUCTURE OF 5'-DEOXY-5'-METHYLTHIOADENOSINE PHOSPHORYLASE COMPLEXED WITH MTA AND SULFATE ION | Descriptor: | 5'-DEOXY-5'-METHYLTHIOADENOSINE, 5'-METHYLTHIOADENOSINE PHOSPHORYLASE, SULFATE ION | Authors: | Appleby, T.C, Mathews, I.I, Porcelli, M, Cacciapuoti, G, Ealick, S.E. | Deposit date: | 2001-06-15 | Release date: | 2001-10-26 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Three-dimensional structure of a hyperthermophilic 5'-deoxy-5'-methylthioadenosine phosphorylase from Sulfolobus solfataricus. J.Biol.Chem., 276, 2001
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1JE1
| 5'-DEOXY-5'-METHYLTHIOADENOSINE PHOSPHORYLASE COMPLEX WITH GUANOSINE AND SULFATE | Descriptor: | 5'-METHYLTHIOADENOSINE PHOSPHORYLASE, GUANOSINE, SULFATE ION | Authors: | Appleby, T.C, Mathews, I.I, Porcelli, M, Cacciapuoti, G, Ealick, S.E. | Deposit date: | 2001-06-15 | Release date: | 2001-10-26 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Three-dimensional structure of a hyperthermophilic 5'-deoxy-5'-methylthioadenosine phosphorylase from Sulfolobus solfataricus. J.Biol.Chem., 276, 2001
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2AI2
| Purine nucleoside phosphorylase from calf spleen | Descriptor: | ((2S,3AS,4R,6S)-4-(HYDROXYMETHYL)-6-(4-OXO-4,5-DIHYDRO-3H-PYRROLO[3,2-D]PYRIMIDIN-7-YL)-TETRAHYDROFURO[3,4-D][1,3]DIOXO L-2-YL)METHYLPHOSPHONIC ACID, MAGNESIUM ION, Purine nucleoside phosphorylase, ... | Authors: | Toms, A.V, Wang, W, Li, Y, Ganem, B, Ealick, S.E. | Deposit date: | 2005-07-28 | Release date: | 2005-10-25 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Novel multisubstrate inhibitors of mammalian purine nucleoside phosphorylase. Acta Crystallogr.,Sect.D, 61, 2005
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