3RWA
 
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3RWT
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8H3D
 | | Structure of apo SARS-CoV-2 spike protein with one RBD up | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein,Fibritin | | Authors: | Meng, F, Wang, Q, Xie, Y, Ni, X, Huang, N. | | Deposit date: | 2022-10-08 | | Release date: | 2023-03-22 | | Last modified: | 2024-11-13 | | Method: | ELECTRON MICROSCOPY (3.27 Å) | | Cite: | In Silico Discovery of Small Molecule Modulators Targeting the Achilles' Heel of SARS-CoV-2 Spike Protein.
Acs Cent.Sci., 9, 2023
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8H3E
 | | Complex structure of a small molecule (SPC-14) bound SARS-CoV-2 spike protein, closed state | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 7-(6-nitro-2,3-dihydroindol-1-yl)-7-oxidanylidene-heptanoic acid, Spike glycoprotein,Fibritin | | Authors: | Meng, F, Wang, Q, Xie, Y, Ni, X, Huang, N. | | Deposit date: | 2022-10-08 | | Release date: | 2023-03-22 | | Last modified: | 2024-11-06 | | Method: | ELECTRON MICROSCOPY (3.06 Å) | | Cite: | In Silico Discovery of Small Molecule Modulators Targeting the Achilles' Heel of SARS-CoV-2 Spike Protein.
Acs Cent.Sci., 9, 2023
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9IWV
 | | Crystal structure of Lsd18 after incubation with the substrate | | Descriptor: | CHLORIDE ION, FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, ... | | Authors: | Wang, Q, Kim, C.Y, Chen, X. | | Deposit date: | 2024-07-26 | | Release date: | 2025-04-16 | | Last modified: | 2025-05-21 | | Method: | X-RAY DIFFRACTION (1.85 Å) | | Cite: | Mechanistic and molecular insights into iterative triepoxidation catalyzed by monooxygenase MonCI using a natural substrate analog.
Int.J.Biol.Macromol., 311, 2025
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7DTE
 | | SARS-CoV-2 RdRP catalytic complex with T33-1 RNA | | Descriptor: | Non-structural protein 7, Non-structural protein 8, RNA (33-MER), ... | | Authors: | Wang, Q, Gong, P. | | Deposit date: | 2021-01-04 | | Release date: | 2021-10-20 | | Last modified: | 2025-06-25 | | Method: | ELECTRON MICROSCOPY (3 Å) | | Cite: | Remdesivir overcomes the S861 roadblock in SARS-CoV-2 polymerase elongation complex.
Cell Rep, 37, 2021
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7Y9J
 | | Crystal structure of P450 BM3-TMK from Bacillus megaterium in complex with 5-nitro-1,2-benzisoxazole | | Descriptor: | 5-nitro-1,2-benzoxazole, Bifunctional cytochrome P450/NADPH--P450 reductase, PROTOPORPHYRIN IX CONTAINING FE | | Authors: | Wang, Q, Zhang, L.L, Liu, W.D, Huang, J.-W, Yang, Y, Chen, C.-C, Guo, R.-T. | | Deposit date: | 2022-06-24 | | Release date: | 2023-06-28 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (1.83 Å) | | Cite: | Engineering of a P450-based Kemp eliminase with a new mechanism
Chinese J Catal, 47, 2023
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7Y9K
 | | Crystal structure of P450 BM3-TMK from Bacillus megaterium | | Descriptor: | Bifunctional cytochrome P450/NADPH--P450 reductase, PROTOPORPHYRIN IX CONTAINING FE | | Authors: | Wang, Q, Zhang, L.L, Liu, W.D, Huang, J.-W, Yang, Y, Chen, C.-C, Guo, R.-T. | | Deposit date: | 2022-06-25 | | Release date: | 2023-06-28 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.23 Å) | | Cite: | Engineering of a P450-based Kemp eliminase with a new mechanism
Chinese J Catal, 47, 2023
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8YMK
 | | Localized reconstruction of Hepatitis B virus surface antigen dimer in the subviral particle with D2 symmetry from dataset A0 | | Descriptor: | Isoform S of Large envelope protein | | Authors: | Wang, T, Cao, L, Mu, A, Wang, Q, Rao, Z.H. | | Deposit date: | 2024-03-09 | | Release date: | 2024-09-18 | | Last modified: | 2024-10-09 | | Method: | ELECTRON MICROSCOPY (3.7 Å) | | Cite: | Inherent symmetry and flexibility in hepatitis B virus subviral particles.
Science, 385, 2024
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8YMJ
 | | Cryo-EM structure of Hepatitis B virus surface antigen subviral particle with D2 symmetry | | Descriptor: | Isoform S of Large envelope protein | | Authors: | Wang, T, Cao, L, Mu, A, Wang, Q, Rao, Z.H. | | Deposit date: | 2024-03-09 | | Release date: | 2024-09-18 | | Last modified: | 2024-10-09 | | Method: | ELECTRON MICROSCOPY (6.6 Å) | | Cite: | Inherent symmetry and flexibility in hepatitis B virus subviral particles.
Science, 385, 2024
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5DO2
 | | Complex structure of MERS-RBD bound with 4C2 antibody | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 4C2 heavy chain, 4C2 light chain, ... | | Authors: | Li, Y, Wan, Y, Liu, P, Zhao, J, Lu, G, Qi, J, Wang, Q, Lu, X, Wu, Y, Liu, W, Yuen, K.Y, Perlman, S, Gao, G.F, Yan, J. | | Deposit date: | 2015-09-10 | | Release date: | 2015-10-14 | | Last modified: | 2024-11-06 | | Method: | X-RAY DIFFRACTION (2.409 Å) | | Cite: | A humanized neutralizing antibody against MERS-CoV targeting the receptor-binding domain of the spike protein.
Cell Res., 25, 2015
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3S8A
 | | Structure of Yeast Ribonucleotide Reductase R293A with dGTP | | Descriptor: | 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Ribonucleoside-diphosphate reductase large chain 1 | | Authors: | Ahmad, M.F, Kaushal, P.S, Wan, Q, Wijeratna, S.R, Huang, M, Dealwis, C.D. | | Deposit date: | 2011-05-27 | | Release date: | 2012-04-11 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | Structural and biochemical basis of lethal mutant R293A of yeast ribonucleotide reductase
To be Published
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3S87
 | | Structure of Yeast Ribonucleotide Reductase 1 with dGTP and ADP | | Descriptor: | 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | | Authors: | Ahmad, M.F, Kaushal, P.S, Wan, Q, Wijeratna, S.R, Huang, M, Dealwis, C.D. | | Deposit date: | 2011-05-27 | | Release date: | 2012-04-11 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (2.25 Å) | | Cite: | Structural and biochemical basis of lethal mutant R293A of yeast ribonucleotide reductase
To be Published
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3S8C
 | | Structure of Yeast Ribonucleotide Reductase 1 R293A with AMPPNP and CDP | | Descriptor: | CYTIDINE-5'-DIPHOSPHATE, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... | | Authors: | Ahmad, M.F, Kaushal, P.S, Wan, Q, Wijeratna, S.R, Huang, M, Dealwis, C.D. | | Deposit date: | 2011-05-27 | | Release date: | 2012-04-11 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2.77 Å) | | Cite: | Structural and biochemical basis of lethal mutant R293A of yeast ribonucleotide reductase
To be Published
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3EL2
 | | Crystal Structure of Monomeric Actin Bound to Ca-ATP | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Actin-5C, CALCIUM ION | | Authors: | Nair, U.B, Joel, P.B, Wan, Q, Lowey, S, Rould, M.A, Trybus, K.M. | | Deposit date: | 2008-09-19 | | Release date: | 2008-10-07 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Crystal structures of monomeric actin bound to cytochalasin D.
J.Mol.Biol., 384, 2008
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3EKU
 | | Crystal Structure of Monomeric Actin bound to Cytochalasin D | | Descriptor: | (3S,3aR,4S,6S,6aR,7E,10S,12R,13E,15R,15aR)-3-benzyl-6,12-dihydroxy-4,10,12-trimethyl-5-methylidene-1,11-dioxo-2,3,3a,4,5,6,6a,9,10,11,12,15-dodecahydro-1H-cycloundeca[d]isoindol-15-yl acetate, ADENOSINE-5'-TRIPHOSPHATE, Actin-5C, ... | | Authors: | Nair, U.B, Joel, P.B, Wan, Q, Lowey, S, Rould, M.A, Trybus, K.M. | | Deposit date: | 2008-09-19 | | Release date: | 2008-10-07 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Crystal structures of monomeric actin bound to cytochalasin D.
J.Mol.Biol., 384, 2008
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3EKS
 | | Crystal Structure of Monomeric Actin bound to Cytochalasin D | | Descriptor: | (3S,3aR,4S,6S,6aR,7E,10S,12R,13E,15R,15aR)-3-benzyl-6,12-dihydroxy-4,10,12-trimethyl-5-methylidene-1,11-dioxo-2,3,3a,4,5,6,6a,9,10,11,12,15-dodecahydro-1H-cycloundeca[d]isoindol-15-yl acetate, ADENOSINE-5'-TRIPHOSPHATE, Actin-5C, ... | | Authors: | Nair, U.B, Joel, P.B, Wan, Q, Lowey, S, Rould, M.A, Trybus, K.M. | | Deposit date: | 2008-09-19 | | Release date: | 2008-10-07 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Crystal structures of monomeric actin bound to cytochalasin D.
J.Mol.Biol., 384, 2008
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7FIF
 | | Cryo-EM structure of the hedgehog release protein Disp from water bear (Hypsibius dujardini) | | Descriptor: | Protein dispatched-like protein 1 | | Authors: | Luo, Y, Wan, G, Wang, Q, Zhao, Y, Cong, Y, Li, D. | | Deposit date: | 2021-07-31 | | Release date: | 2021-09-08 | | Last modified: | 2024-06-12 | | Method: | ELECTRON MICROSCOPY (6.5 Å) | | Cite: | Architecture of Dispatched, a Transmembrane Protein Responsible for Hedgehog Release.
Front Mol Biosci, 8, 2021
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6KWF
 | | Crystal Structure Analysis of Endo-beta-1,4-xylanase II Complexed with Xylotriose | | Descriptor: | Endo-1,4-beta-xylanase 2, GLYCEROL, IODIDE ION, ... | | Authors: | Li, C, Wan, Q. | | Deposit date: | 2019-09-06 | | Release date: | 2020-12-30 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (1.22 Å) | | Cite: | Studying the Role of a Single Mutation of a Family 11 Glycoside Hydrolase Using High-Resolution X-ray Crystallography.
Protein J., 39, 2020
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6KWG
 | | Crystal Structure Analysis of Endo-beta-1,4-xylanase II Complexed with Xylotriose | | Descriptor: | Endo-1,4-beta-xylanase 2, IODIDE ION, beta-D-xylopyranose-(1-4)-beta-D-xylopyranose-(1-4)-beta-D-xylopyranose | | Authors: | Li, C, Wan, Q. | | Deposit date: | 2019-09-06 | | Release date: | 2020-12-30 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (1.694 Å) | | Cite: | Studying the Role of a Single Mutation of a Family 11 Glycoside Hydrolase Using High-Resolution X-ray Crystallography.
Protein J., 39, 2020
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6KWC
 | | Crystal Structure Analysis of Endo-beta-1,4-xylanase II | | Descriptor: | Endo-1,4-beta-xylanase 2, GLYCEROL, IODIDE ION | | Authors: | Li, C, Wan, Q. | | Deposit date: | 2019-09-06 | | Release date: | 2021-01-27 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (1.3 Å) | | Cite: | Studying the Role of a Single Mutation of a Family 11 Glycoside Hydrolase Using High-Resolution X-ray Crystallography.
Protein J., 39, 2020
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2HF4
 | | Crystal structure of Monomeric Actin in its ATP-bound state | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Actin-5C, CALCIUM ION | | Authors: | Rould, M.A, Wan, Q, Joel, P.B, Lowey, S, Trybus, K.M. | | Deposit date: | 2006-06-22 | | Release date: | 2006-08-29 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Crystal Structures of Expressed Non-polymerizable Monomeric Actin in the ADP and ATP States.
J.Biol.Chem., 281, 2006
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2HF3
 | | Crystal structure of monomeric Actin in the ADP bound state | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin-5C, CALCIUM ION | | Authors: | Rould, M.A, Wan, Q, Joel, P.B, Lowey, S, Trybus, K.M. | | Deposit date: | 2006-06-22 | | Release date: | 2006-08-29 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Crystal Structures of Expressed Non-polymerizable Monomeric Actin in the ADP and ATP States.
J.Biol.Chem., 281, 2006
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6JWB
 | | Crystal Structures of Endo-beta-1,4-xylanase II Complexed with Xylotriose | | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Endo-1,4-beta-xylanase 2, IODIDE ION, ... | | Authors: | Li, C, Wan, Q. | | Deposit date: | 2019-04-19 | | Release date: | 2020-04-22 | | Last modified: | 2025-03-12 | | Method: | X-RAY DIFFRACTION (1.15 Å) | | Cite: | Studying the Role of a Single Mutation of a Family 11 Glycoside Hydrolase Using High-Resolution X-ray Crystallography.
Protein J., 39, 2020
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3WP1
 | | Phosphorylation-dependent interaction between tumor suppressors Dlg and Lgl | | Descriptor: | Disks large homolog 4, Lethal(2) giant larvae protein homolog 2, SULFATE ION | | Authors: | Zhu, J, Shang, Y, Wan, Q, Xia, Y, Chen, J, Du, Q, Zhang, M. | | Deposit date: | 2014-01-08 | | Release date: | 2014-03-19 | | Last modified: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (2.804 Å) | | Cite: | Phosphorylation-dependent interaction between tumor suppressors Dlg and Lgl
Cell Res., 24, 2014
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