8H3E

Complex structure of a small molecule (SPC-14) bound SARS-CoV-2 spike protein, closed state

Summary for 8H3E

Entry DOI	10.2210/pdb8h3e/pdb
EMDB information	34465
Descriptor	Spike glycoprotein,Fibritin, 7-(6-nitro-2,3-dihydroindol-1-yl)-7-oxidanylidene-heptanoic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose (3 entities in total)
Functional Keywords	sars-cov-2, spike protein, complex, small molecule, closed, viral protein
Biological source	Severe acute respiratory syndrome coronavirus 2 More
Total number of polymer chains	3
Total formula weight	428252.14
Authors	Meng, F.,Wang, Q.,Xie, Y.,Ni, X.,Huang, N. (deposition date: 2022-10-08, release date: 2023-03-22)
Primary citation	Wang, Q.,Meng, F.,Xie, Y.,Wang, W.,Meng, Y.,Li, L.,Liu, T.,Qi, J.,Ni, X.,Zheng, S.,Huang, J.,Huang, N. In Silico Discovery of Small Molecule Modulators Targeting the Achilles' Heel of SARS-CoV-2 Spike Protein. Acs Cent.Sci., 9:252-265, 2023 Cited by PubMed: 36844485 DOI: 10.1021/acscentsci.2c01190 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.06 Å)

Structure validation