7Y7H
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![BU of 7y7h by Molmil](/molmil-images/mine/7y7h) | Structure of the Bacterial Ribosome with human tRNA Tyr(GalQ34) and mRNA(UAC) | Descriptor: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | Authors: | Ishiguro, K, Yokoyama, T, Shirouzu, M, Suzuki, T. | Deposit date: | 2022-06-22 | Release date: | 2023-10-25 | Last modified: | 2023-12-27 | Method: | ELECTRON MICROSCOPY (2.51 Å) | Cite: | Glycosylated queuosines in tRNAs optimize translational rate and post-embryonic growth. Cell, 186, 2023
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8IOY
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![BU of 8ioy by Molmil](/molmil-images/mine/8ioy) | Structure of ATP7B C983S/C985S/D1027A mutant with AMP-PNP | Descriptor: | Copper-transporting ATPase 2, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | Authors: | Yang, G, Xu, L, Guo, J, Wu, Z. | Deposit date: | 2023-03-13 | Release date: | 2023-04-26 | Last modified: | 2023-05-03 | Method: | ELECTRON MICROSCOPY (4 Å) | Cite: | Structures of the human Wilson disease copper transporter ATP7B. Cell Rep, 42, 2023
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4IKT
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![BU of 4ikt by Molmil](/molmil-images/mine/4ikt) | Crystal structure of truncated (delta 1-89) human methionine aminopeptidase Type 1 in complex with N1-(5-chloro-6-methyl-2-(pyridin-2-yl)pyrimidin-4-yl)-N2-(5-(trifluoromethyl)pyridin-2-yl)ethane-1,2-diamine | Descriptor: | COBALT (II) ION, GLYCEROL, Methionine aminopeptidase 1, ... | Authors: | Addlagatta, A, Kishor, C, Arya, T. | Deposit date: | 2012-12-28 | Release date: | 2013-12-11 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Identification, Biochemical and Structural Evaluation of Species-Specific Inhibitors against Type I Methionine Aminopeptidases J.Med.Chem., 56, 2013
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4IKR
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![BU of 4ikr by Molmil](/molmil-images/mine/4ikr) | Crystal structure of Type 1 human methionine aminopeptidase in complex with 2-(4-(5-chloro-6-methyl-2-(pyridin-2-yl)pyrimidin-4-yl)piperazin-1-yl)ethanol | Descriptor: | 2-{4-[5-chloro-6-methyl-2-(pyridin-2-yl)pyrimidin-4-yl]piperazin-1-yl}ethanol, COBALT (II) ION, GLYCEROL, ... | Authors: | Addlagatta, A, Kishor, C, Arya, T. | Deposit date: | 2012-12-28 | Release date: | 2013-12-11 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (1.78 Å) | Cite: | Identification, Biochemical and Structural Evaluation of Species-Specific Inhibitors against Type I Methionine Aminopeptidases J.Med.Chem., 56, 2013
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4IKU
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![BU of 4iku by Molmil](/molmil-images/mine/4iku) | Crystal structure of truncated (delta 1-89) human methionine aminopeptidase Type 1 in complex with 2-((5-chloro-6-methyl-2-(pyridin-2-yl)pyrimidin-4-yl)amino)-3-phenylpropanamide | Descriptor: | COBALT (II) ION, Methionine aminopeptidase 1, Nalpha-[5-chloro-6-methyl-2-(pyridin-2-yl)pyrimidin-4-yl]-D-phenylalaninamide, ... | Authors: | Addlagatta, A, Kishor, C, Arya, T. | Deposit date: | 2012-12-28 | Release date: | 2013-12-11 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (1.3 Å) | Cite: | Identification, Biochemical and Structural Evaluation of Species-Specific Inhibitors against Type I Methionine Aminopeptidases J.Med.Chem., 56, 2013
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4IU6
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![BU of 4iu6 by Molmil](/molmil-images/mine/4iu6) | Human Methionine Aminopeptidase in complex with FZ1: Pyridinylquinazolines Selectively Inhibit Human Methionine Aminopeptidase-1 | Descriptor: | 4-[4-(4-methoxyphenyl)piperazin-1-yl]-2-(pyridin-2-yl)quinazoline, COBALT (II) ION, Methionine aminopeptidase 1, ... | Authors: | Gabelli, S.B, Zhang, F, Miller, M, Liu, J, Amzel, L.M. | Deposit date: | 2013-01-19 | Release date: | 2013-05-01 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Pyridinylquinazolines selectively inhibit human methionine aminopeptidase-1 in cells. J.Med.Chem., 56, 2013
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4IKS
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![BU of 4iks by Molmil](/molmil-images/mine/4iks) | Crystal structure of truncated (delta 1-89) human methionine aminopeptidase Type 1 in complex with N1-(5-chloro-6-methyl-2-(pyridin-2-yl)pyrimidin-4-yl)-N2-(6-(trifluoromethyl)pyridin-2-yl)ethane-1,2-diamine | Descriptor: | COBALT (II) ION, GLYCEROL, Methionine aminopeptidase 1, ... | Authors: | Addlagatta, A, Kishor, C, Arya, T. | Deposit date: | 2012-12-28 | Release date: | 2013-12-11 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Identification, Biochemical and Structural Evaluation of Species-Specific Inhibitors against Type I Methionine Aminopeptidases J.Med.Chem., 56, 2013
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4HXX
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![BU of 4hxx by Molmil](/molmil-images/mine/4hxx) | Pyridinylpyrimidines selectively inhibit human methionine aminopeptidase-1 | Descriptor: | (1R)-N~2~-[5-chloro-2-(5-chloropyridin-2-yl)-6-methylpyrimidin-4-yl]-1-phenyl-N~1~-(4-phenylbutyl)ethane-1,2-diamine, COBALT (II) ION, Methionine aminopeptidase 1, ... | Authors: | Gabelli, S.B, Zhang, F, Liu, J, Amzel, L.M. | Deposit date: | 2012-11-12 | Release date: | 2013-04-03 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.09 Å) | Cite: | Pyridinylpyrimidines selectively inhibit human methionine aminopeptidase-1. Bioorg.Med.Chem., 21, 2013
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7VH8
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![BU of 7vh8 by Molmil](/molmil-images/mine/7vh8) | Crystal structure of SARS-CoV-2 main protease in complex with protease inhibitor PF-07321332 | Descriptor: | (1R,2S,5S)-N-{(1E,2S)-1-imino-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl}-6,6-dimethyl-3-[3-methyl-N-(trifluoroacetyl)-L-valyl]-3-azabicyclo[3.1.0]hexane-2-carboxamide, 3C-like proteinase, DIMETHYL SULFOXIDE | Authors: | Zhao, Y, Zhang, Q, Yang, H, Rao, Z. | Deposit date: | 2021-09-21 | Release date: | 2021-11-03 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.59 Å) | Cite: | Crystal structure of SARS-CoV-2 main protease in complex with protease inhibitor PF-07321332. Protein Cell, 13, 2022
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7XUK
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![BU of 7xuk by Molmil](/molmil-images/mine/7xuk) | |
7XUM
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![BU of 7xum by Molmil](/molmil-images/mine/7xum) | Structure of ATP7B C983S/C985S/D1027A mutant with Cu+ in presence of ATOX1 | Descriptor: | COPPER (II) ION, Copper-transporting ATPase 2 | Authors: | Yang, G, Xu, L, Chang, S, Guo, J, Wu, Z. | Deposit date: | 2022-05-19 | Release date: | 2023-05-03 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Structures of the human Wilson disease copper transporter ATP7B. Cell Rep, 42, 2023
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7XUN
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![BU of 7xun by Molmil](/molmil-images/mine/7xun) | |
7XUO
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![BU of 7xuo by Molmil](/molmil-images/mine/7xuo) | Structure of ATP7B C983S/C985S/D1027A mutant with cisplatin in presence of ATOX1 | Descriptor: | Copper-transporting ATPase 2, PLATINUM (II) ION | Authors: | Yang, G, Xu, L, Chang, S, Guo, J, Wu, Z. | Deposit date: | 2022-05-19 | Release date: | 2023-04-26 | Last modified: | 2023-05-03 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Structures of the human Wilson disease copper transporter ATP7B. Cell Rep, 42, 2023
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7XZ4
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![BU of 7xz4 by Molmil](/molmil-images/mine/7xz4) | |
4FWX
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![BU of 4fwx by Molmil](/molmil-images/mine/4fwx) | Aquoferric F33Y CuB myoglobin (F33Y L29H F43H sperm whale myoglobin) | Descriptor: | Myoglobin, PROTOPORPHYRIN IX CONTAINING FE | Authors: | Gao, Y.-G, Stoner-Ma, D, Robinson, H, Petrik, I.D, Miner, K.D, Lu, Y. | Deposit date: | 2012-07-02 | Release date: | 2012-07-18 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | A Designed Functional Metalloenzyme that Reduces O(2) to H(2) O with Over One Thousand Turnovers. Angew.Chem.Int.Ed.Engl., 51, 2012
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