7ZSU
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![BU of 7zsu by Molmil](/molmil-images/mine/7zsu) | Crystal structure of CYP125 from Mycobacterium tuberculosis in complex with an inhibitor | Descriptor: | PROTOPORPHYRIN IX CONTAINING FE, SULFATE ION, Steroid C26-monooxygenase, ... | Authors: | Snee, M, Katariya, M, Levy, C, Leys, D. | Deposit date: | 2022-05-09 | Release date: | 2023-04-05 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structure Based Discovery of Inhibitors of CYP125 and CYP142 from Mycobacterium tuberculosis. Chemistry, 29, 2023
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7ZLZ
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![BU of 7zlz by Molmil](/molmil-images/mine/7zlz) | Crystal structure of CYP125 from Mycobacterium tuberculosis in complex with an inhibitor | Descriptor: | PROTOPORPHYRIN IX CONTAINING FE, SULFATE ION, Steroid C26-monooxygenase, ... | Authors: | Snee, M, Katariya, M, Levy, C, Leys, D. | Deposit date: | 2022-04-17 | Release date: | 2023-04-05 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.89 Å) | Cite: | Structure Based Discovery of Inhibitors of CYP125 and CYP142 from Mycobacterium tuberculosis. Chemistry, 29, 2023
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5A35
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![BU of 5a35 by Molmil](/molmil-images/mine/5a35) | Crystal structure of Glycine Cleavage Protein H-Like (GcvH-L) from Streptococcus pyogenes | Descriptor: | GLYCINE CLEAVAGE SYSTEM H PROTEIN, PENTAETHYLENE GLYCOL | Authors: | Rack, J.G.M, Morra, R, Barkauskaite, E, Kraehenbuehl, R, Ariza, A, Qu, Y, Ortmayer, M, Leidecker, O, Cameron, D.R, Matic, I, Peleg, A.Y, Leys, D, Traven, A, Ahel, I. | Deposit date: | 2015-05-27 | Release date: | 2015-07-29 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Identification of a Class of Protein Adp-Ribosylating Sirtuins in Microbial Pathogens. Mol.Cell, 59, 2015
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3SIJ
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![BU of 3sij by Molmil](/molmil-images/mine/3sij) | |
3SII
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![BU of 3sii by Molmil](/molmil-images/mine/3sii) | |
5A3A
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![BU of 5a3a by Molmil](/molmil-images/mine/5a3a) | Crystal structure of the ADP-ribosylating sirtuin (SirTM) from Streptococcus pyogenes (Apo form) | Descriptor: | 1,2-ETHANEDIOL, GLYCINE, SIR2 FAMILY PROTEIN, ... | Authors: | Rack, J.G.M, Morra, R, Barkauskaite, E, Kraehenbuehl, R, Ariza, A, Qu, Y, Ortmayer, M, Leidecker, O, Cameron, D.R, Matic, I, Peleg, A.Y, Leys, D, Traven, A, Ahel, I. | Deposit date: | 2015-05-28 | Release date: | 2015-07-29 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.54 Å) | Cite: | Identification of a Class of Protein Adp-Ribosylating Sirtuins in Microbial Pathogens. Mol.Cell, 59, 2015
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5D6S
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![BU of 5d6s by Molmil](/molmil-images/mine/5d6s) | Structure of epoxyqueuosine reductase from Streptococcus thermophilus. | Descriptor: | COBALAMIN, Epoxyqueuosine reductase, IRON/SULFUR CLUSTER | Authors: | Payne, K.A.P, Fisher, K, Dunstan, M.S, Sjuts, H, Leys, D. | Deposit date: | 2015-08-12 | Release date: | 2015-09-23 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.65 Å) | Cite: | Epoxyqueuosine Reductase Structure Suggests a Mechanism for Cobalamin-dependent tRNA Modification. J.Biol.Chem., 290, 2015
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3SIH
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![BU of 3sih by Molmil](/molmil-images/mine/3sih) | |
5E1W
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![BU of 5e1w by Molmil](/molmil-images/mine/5e1w) | |
5E20
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![BU of 5e20 by Molmil](/molmil-images/mine/5e20) | Crystal structure of the organohalide sensing RdhR-CbdbA1625 transcriptional regulator in the 2,3-dichlorophenol bound form | Descriptor: | 2,3-dichlorophenol, Transcriptional regulator, MarR family | Authors: | Quezada, C.P, Dunstan, M.S, Fisher, K, Leys, D. | Deposit date: | 2015-09-30 | Release date: | 2016-10-05 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.97 Å) | Cite: | Crystal structures of RdhRCbdbA1625 provide insight into sensing of chloroaromatic compounds by MarR-type regulators To be published
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5E1Z
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![BU of 5e1z by Molmil](/molmil-images/mine/5e1z) | Crystal structure of the organohalide sensing RdhR-CbdbA1625 transcriptional regulator in the 2,4-dichlorophenol bound form | Descriptor: | 2,4-dichlorophenol, Transcriptional regulator, MarR family | Authors: | Quezada, C.P, Dunstan, M.S, Fisher, K, Leys, D. | Deposit date: | 2015-09-30 | Release date: | 2016-10-05 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.66 Å) | Cite: | Crystal structures of RdhRCbdbA1625 provide insight into sensing of chloroaromatic compounds by MarR-type regulators to be published
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5E1X
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![BU of 5e1x by Molmil](/molmil-images/mine/5e1x) | Crystal structure of the organohalide sensing RdhR-CbdbA1625 transcriptional regulator in the 3,4-dichlorophenol bound form | Descriptor: | 3,4-dichlorophenol, Transcriptional regulator, MarR family | Authors: | Quezada, C.P, Dunstan, M.S, Fisher, K, Leys, D. | Deposit date: | 2015-09-30 | Release date: | 2016-10-05 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.46 Å) | Cite: | Crystal structures of RdhRCbdbA1625 provide insight into sensing of chloroaromatic compounds by MarR-type regulators TO BE PUBLISHED
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1CXY
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![BU of 1cxy by Molmil](/molmil-images/mine/1cxy) | STRUCTURE AND CHARACTERIZATION OF ECTOTHIORHODOSPIRA VACUOLATA CYTOCHROME B558, A PROKARYOTIC HOMOLOGUE OF CYTOCHROME B5 | Descriptor: | CYTOCHROME B5, PROTOPORPHYRIN IX CONTAINING FE | Authors: | Kostanjevecki, V, Leys, D, Van Driessche, G, Meyer, T.E, Cusanovich, M.A, Fischer, U, Guisez, Y, Van Beeumen, J. | Deposit date: | 1999-08-31 | Release date: | 1999-09-10 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Structure and characterization of Ectothiorhodospira vacuolata cytochrome b(558), a prokaryotic homologue of cytochrome b(5). J.Biol.Chem., 274, 1999
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4KVQ
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![BU of 4kvq by Molmil](/molmil-images/mine/4kvq) | Crystal Structure of Prochlorococcus marinus aldehyde-deformylating oxygenase wild type with palmitic acid bound | Descriptor: | Aldehyde decarbonylase, FE (III) ION, PALMITIC ACID | Authors: | Levy, C.W, Khara, B, Menon, N, Mansell, D, Das, D, Marsh, E.N.G, Leys, D, Scrutton, N.S. | Deposit date: | 2013-05-23 | Release date: | 2013-06-26 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.842 Å) | Cite: | Production of propane and other short-chain alkanes by structure-based engineering of ligand specificity in aldehyde-deformylating oxygenase. Chembiochem, 14, 2013
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1JRY
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![BU of 1jry by Molmil](/molmil-images/mine/1jry) | Crystal structure of Arg402Lys mutant flavocytochrome c3 from Shewanella frigidimarina | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, FLAVOCYTOCHROME C, FUMARIC ACID, ... | Authors: | Mowat, C.G, Moysey, R, Miles, C.S, Leys, D, Doherty, M.K, Taylor, P, Walkinshaw, M.D, Reid, G.A, Chapman, S.K. | Deposit date: | 2001-08-15 | Release date: | 2001-11-02 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Kinetic and crystallographic analysis of the key active site acid/base arginine in a soluble fumarate reductase. Biochemistry, 40, 2001
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8J2X
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![BU of 8j2x by Molmil](/molmil-images/mine/8j2x) | Saccharothrix syringae photocobilins protein, light state | Descriptor: | BILIVERDINE IX ALPHA, COBALAMIN, Cobalamin-binding protein, ... | Authors: | Zhang, S, Poddar, H, Levy, C, Leys, D. | Deposit date: | 2023-04-15 | Release date: | 2024-04-10 | Method: | X-RAY DIFFRACTION (1.98 Å) | Cite: | Photocobilins integrate B12 and bilin photochemistry for enzyme control. Nat Commun, 15, 2024
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8J2Y
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![BU of 8j2y by Molmil](/molmil-images/mine/8j2y) | Acidimicrobiaceae bacterium photocobilins protein, dark state | Descriptor: | 5'-DEOXYADENOSINE, COBALAMIN, DI(HYDROXYETHYL)ETHER, ... | Authors: | Zhang, S, Poddar, H, Levy, W.C, Leys, D. | Deposit date: | 2023-04-15 | Release date: | 2024-04-10 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Photocobilins integrate B12 and bilin photochemistry for enzyme control. Nat Commun, 15, 2024
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8J2W
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![BU of 8j2w by Molmil](/molmil-images/mine/8j2w) | Saccharothrix syringae photocobilins protein, dark state | Descriptor: | 1,4-DIETHYLENE DIOXIDE, 5'-DEOXYADENOSINE, BILIVERDINE IX ALPHA, ... | Authors: | Zhang, S, Poddar, H, Levy, W.C, Leys, D. | Deposit date: | 2023-04-15 | Release date: | 2024-04-10 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Photocobilins integrate B12 and bilin photochemistry for enzyme control. Nat Commun, 15, 2024
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1KSU
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![BU of 1ksu by Molmil](/molmil-images/mine/1ksu) | Crystal Structure of His505Tyr Mutant Flavocytochrome c3 from Shewanella frigidimarina | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, FUMARIC ACID, PROTOPORPHYRIN IX CONTAINING FE, ... | Authors: | Pankhurst, K.L, Mowat, C.G, Miles, C.S, Leys, D, Walkinshaw, M.D, Reid, G.A, Chapman, S.K. | Deposit date: | 2002-01-14 | Release date: | 2002-08-14 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Role of His505 in the soluble fumarate reductase from Shewanella frigidimarina. Biochemistry, 41, 2002
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1JRX
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![BU of 1jrx by Molmil](/molmil-images/mine/1jrx) | Crystal structure of Arg402Ala mutant flavocytochrome c3 from Shewanella frigidimarina | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, FLAVOCYTOCHROME C, FUMARIC ACID, ... | Authors: | Mowat, C.G, Moysey, R, Miles, C.S, Leys, D, Doherty, M.K, Taylor, P, Walkinshaw, M.D, Reid, G.A, Chapman, S.K. | Deposit date: | 2001-08-15 | Release date: | 2001-11-02 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Kinetic and crystallographic analysis of the key active site acid/base arginine in a soluble fumarate reductase. Biochemistry, 40, 2001
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1KSS
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![BU of 1kss by Molmil](/molmil-images/mine/1kss) | Crystal Structure of His505Ala Mutant Flavocytochrome c3 from Shewanella frigidimarina | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, FUMARIC ACID, PROTOPORPHYRIN IX CONTAINING FE, ... | Authors: | Pankhurst, K.L, Mowat, C.G, Miles, C.S, Leys, D, Walkinshaw, M.D, Reid, G.A, Chapman, S.K. | Deposit date: | 2002-01-14 | Release date: | 2002-08-14 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Role of His505 in the soluble fumarate reductase from Shewanella frigidimarina. Biochemistry, 41, 2002
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1JRZ
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![BU of 1jrz by Molmil](/molmil-images/mine/1jrz) | Crystal structure of Arg402Tyr mutant flavocytochrome c3 from Shewanella frigidimarina | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, FLAVOCYTOCHROME C, FUMARIC ACID, ... | Authors: | Mowat, C.G, Moysey, R, Miles, C.S, Leys, D, Doherty, M.K, Taylor, P, Walkinshaw, M.D, Reid, G.A, Chapman, S.K. | Deposit date: | 2001-08-15 | Release date: | 2001-11-02 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Kinetic and crystallographic analysis of the key active site acid/base arginine in a soluble fumarate reductase. Biochemistry, 40, 2001
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7AE7
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![BU of 7ae7 by Molmil](/molmil-images/mine/7ae7) | |
7AE4
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![BU of 7ae4 by Molmil](/molmil-images/mine/7ae4) | |
7AE5
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![BU of 7ae5 by Molmil](/molmil-images/mine/7ae5) | |