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2F4J
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BU of 2f4j by Molmil
Structure of the Kinase Domain of an Imatinib-Resistant Abl Mutant in Complex with the Aurora Kinase Inhibitor VX-680
Descriptor: CYCLOPROPANECARBOXYLIC ACID {4-[4-(4-METHYL-PIPERAZIN-1-YL)-6-(5-METHYL-2H-PYRAZOL-3-YLAMINO)-PYRIMIDIN-2-YLSULFANYL]-PHENYL}-AMIDE, Proto-oncogene tyrosine-protein kinase ABL1
Authors:Young, M.A, Shah, N.P, Chao, L.H, Zarrinkar, P, Sawyers, P, Kuriyan, J.
Deposit date:2005-11-23
Release date:2006-01-24
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.91 Å)
Cite:Structure of the kinase domain of an imatinib-resistant Abl mutant in complex with the Aurora kinase inhibitor VX-680.
Cancer Res., 66, 2006
1SPS
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BU of 1sps by Molmil
BINDING OF A HIGH AFFINITY PHOSPHOTYROSYL PEPTIDE TO THE SRC SH2 DOMAIN: CRYSTAL STRUCTURES OF THE COMPLEXED AND PEPTIDE-FREE FORMS
Descriptor: PEPTIDE YEEI, SRC SH2 DOMAIN
Authors:Waksman, G, Kuriyan, J.
Deposit date:1993-03-05
Release date:1994-05-31
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Binding of a high affinity phosphotyrosyl peptide to the Src SH2 domain: crystal structures of the complexed and peptide-free forms.
Cell(Cambridge,Mass.), 72, 1993
1SHB
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BU of 1shb by Molmil
CRYSTAL STRUCTURE OF THE PHOSPHOTYROSINE RECOGNITION DOMAIN SH2 OF V-SRC COMPLEXED WITH TYROSINE-PHOSPHORYLATED PEPTIDES
Descriptor: PHOSPHOPEPTIDE B, V-SRC SH2 DOMAIN
Authors:Waksman, G, Kuriyan, J.
Deposit date:1992-08-18
Release date:1993-10-31
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of the phosphotyrosine recognition domain SH2 of v-src complexed with tyrosine-phosphorylated peptides.
Nature, 358, 1992
1SHA
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BU of 1sha by Molmil
CRYSTAL STRUCTURE OF THE PHOSPHOTYROSINE RECOGNITION DOMAIN SH2 OF V-SRC COMPLEXED WITH TYROSINE-PHOSPHORYLATED PEPTIDES
Descriptor: PHOSPHOPEPTIDE A, V-SRC SH2 DOMAIN
Authors:Waksman, G, Kuriyan, J.
Deposit date:1992-08-18
Release date:1993-10-31
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Crystal structure of the phosphotyrosine recognition domain SH2 of v-src complexed with tyrosine-phosphorylated peptides.
Nature, 358, 1992
1U4H
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BU of 1u4h by Molmil
Crystal structure of an oxygen binding H-NOX domain related to soluble guanylate cyclases (oxygen complex)
Descriptor: GLYCEROL, Heme-based Methyl-accepting Chemotaxis Protein, OXYGEN MOLECULE, ...
Authors:Pellicena, P, Karow, D.S, Boon, E.M, Marletta, M.A, Kuriyan, J.
Deposit date:2004-07-25
Release date:2004-08-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.07 Å)
Cite:Crystal structure of an oxygen-binding heme domain related to soluble guanylate cyclases.
Proc.Natl.Acad.Sci.Usa, 101, 2004
1U55
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BU of 1u55 by Molmil
Crystal structure of an oxygen binding H-NOX domain related to soluble guanylate cyclases (oxygen complex)
Descriptor: CHLORIDE ION, Heme-based Methyl-accepting Chemotaxis Protein, OXYGEN MOLECULE, ...
Authors:Pellicena, P, Karow, D.S, Boon, E.M, Marletta, M.A, Kuriyan, J.
Deposit date:2004-07-27
Release date:2004-08-31
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.77 Å)
Cite:Crystal structure of an oxygen-binding heme domain related to soluble guanylate cyclases.
Proc.Natl.Acad.Sci.Usa, 101, 2004
1SXJ
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BU of 1sxj by Molmil
Crystal Structure of the Eukaryotic Clamp Loader (Replication Factor C, RFC) Bound to the DNA Sliding Clamp (Proliferating Cell Nuclear Antigen, PCNA)
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Activator 1 37 kDa subunit, Activator 1 40 kDa subunit, ...
Authors:Bowman, G.D, O'Donnell, M, Kuriyan, J.
Deposit date:2004-03-30
Release date:2004-06-22
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Structural analysis of a eukaryotic sliding DNA clamp-clamp loader complex.
Nature, 429, 2004
1SPR
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BU of 1spr by Molmil
BINDING OF A HIGH AFFINITY PHOSPHOTYROSYL PEPTIDE TO THE SRC SH2 DOMAIN: CRYSTAL STRUCTURES OF THE COMPLEXED AND PEPTIDE-FREE FORMS
Descriptor: PHOSPHATE ION, SRC TYROSINE KINASE SH2 DOMAIN
Authors:Waksman, G, Kuriyan, J.
Deposit date:1993-03-05
Release date:1994-05-31
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Binding of a high affinity phosphotyrosyl peptide to the Src SH2 domain: crystal structures of the complexed and peptide-free forms.
Cell(Cambridge,Mass.), 72, 1993
1U56
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BU of 1u56 by Molmil
Crystal structure of an oxygen binding H-NOX domain related to soluble guanylate cyclases (Water-ligated, ferric form)
Descriptor: CHLORIDE ION, Heme-based Methyl-accepting chemotaxis protein, PROTOPORPHYRIN IX CONTAINING FE
Authors:Pellicena, P, Karow, D.S, Boon, E.M, Marletta, M.A, Kuriyan, J.
Deposit date:2004-07-27
Release date:2004-08-31
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure of an oxygen-binding heme domain related to soluble guanylate cyclases.
Proc.Natl.Acad.Sci.Usa, 101, 2004
3TF1
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BU of 3tf1 by Molmil
Crystal structure of an H-NOX protein from T. tengcongensis under 6 atm of xenon
Descriptor: ACETATE ION, Methyl-accepting chemotaxis protein, OXYGEN MOLECULE, ...
Authors:Winter, M.B, Herzik Jr, M.A, Kuriyan, J, Marletta, M.A.
Deposit date:2011-08-15
Release date:2011-11-09
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.0369 Å)
Cite:Tunnels modulate ligand flux in a heme nitric oxide/oxygen binding (H-NOX) domain.
Proc.Natl.Acad.Sci.USA, 108, 2011
3TFF
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BU of 3tff by Molmil
Crystal structure of an H-NOX protein from Nostoc sp. PCC 7120, L67W mutant
Descriptor: Alr2278 protein, MALONIC ACID, PROTOPORPHYRIN IX CONTAINING FE
Authors:Winter, M.B, Herzik Jr, M.A, Kuriyan, J, Marletta, M.A.
Deposit date:2011-08-15
Release date:2011-11-09
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.9401 Å)
Cite:Tunnels modulate ligand flux in a heme nitric oxide/oxygen binding (H-NOX) domain.
Proc.Natl.Acad.Sci.USA, 108, 2011
3TF0
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BU of 3tf0 by Molmil
Crystal structure of an H-NOX protein from T. tengcongensis
Descriptor: ACETATE ION, Methyl-accepting chemotaxis protein, OXYGEN MOLECULE, ...
Authors:Winter, M.B, Herzik Jr, M.A, Kuriyan, J, Marletta, M.A.
Deposit date:2011-08-15
Release date:2011-11-09
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.743 Å)
Cite:Tunnels modulate ligand flux in a heme nitric oxide/oxygen binding (H-NOX) domain.
Proc.Natl.Acad.Sci.USA, 108, 2011
3TFE
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BU of 3tfe by Molmil
Crystal structure of an H-NOX protein from Nostoc sp. PCC 7120, L66W mutant under 6 atm of xenon
Descriptor: Alr2278 protein, MALONIC ACID, PROTOPORPHYRIN IX CONTAINING FE, ...
Authors:Winter, M.B, Herzik Jr, M.A, Kuriyan, J, Marletta, M.A.
Deposit date:2011-08-15
Release date:2011-11-09
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.991 Å)
Cite:Tunnels modulate ligand flux in a heme nitric oxide/oxygen binding (H-NOX) domain.
Proc.Natl.Acad.Sci.USA, 108, 2011
1XDV
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BU of 1xdv by Molmil
Experimentally Phased Structure of Human the Son of Sevenless protein at 4.1 Ang.
Descriptor: Son of sevenless protein homolog 1
Authors:Sondermann, H, Soisson, S.M, Boykevisch, S, Yang, S.S, Bar-Sagi, D, Kuriyan, J.
Deposit date:2004-09-08
Release date:2004-11-02
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (4.1 Å)
Cite:Structural analysis of autoinhibition in the ras activator son of sevenless.
Cell(Cambridge,Mass.), 119, 2004
1XXI
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BU of 1xxi by Molmil
ADP Bound E. coli Clamp Loader Complex
Descriptor: ADENOSINE-5'-DIPHOSPHATE, DNA polymerase III subunit gamma, DNA polymerase III, ...
Authors:Kazmirski, S.L, Podobnik, M, Weitze, T.F, O'Donnell, M, Kuriyan, J.
Deposit date:2004-11-05
Release date:2004-12-07
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (4.1 Å)
Cite:Structural analysis of the inactive state of the Escherichia coli DNA polymerase clamp-loader complex
Proc.Natl.Acad.Sci.USA, 101, 2004
1XD2
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BU of 1xd2 by Molmil
Crystal Structure of a ternary Ras:SOS:Ras*GDP complex
Descriptor: GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, PHOSPHATE ION, ...
Authors:Sondermann, H, Soisson, S.M, Boykevisch, S, Yang, S.S, Bar-Sagi, D, Kuriyan, J.
Deposit date:2004-09-03
Release date:2004-11-02
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural analysis of autoinhibition in the ras activator son of sevenless.
Cell(Cambridge,Mass.), 119, 2004
3TFD
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BU of 3tfd by Molmil
Crystal structure of an H-NOX protein from Nostoc sp. PCC 7120, L66W mutant
Descriptor: Alr2278 protein, MALONIC ACID, PROTOPORPHYRIN IX CONTAINING FE
Authors:Winter, M.B, Herzik Jr, M.A, Kuriyan, J, Marletta, M.A.
Deposit date:2011-08-15
Release date:2011-11-09
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.96 Å)
Cite:Tunnels modulate ligand flux in a heme nitric oxide/oxygen binding (H-NOX) domain.
Proc.Natl.Acad.Sci.USA, 108, 2011
3TFG
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BU of 3tfg by Molmil
Crystal structure of an H-NOX protein from Nostoc sp. PCC 7120, L66W/L67W double mutant
Descriptor: Alr2278 protein, MALONIC ACID, PROTOPORPHYRIN IX CONTAINING FE
Authors:Winter, M.B, Herzik Jr, M.A, Kuriyan, J, Marletta, M.A.
Deposit date:2011-08-15
Release date:2011-11-09
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.9003 Å)
Cite:Tunnels modulate ligand flux in a heme nitric oxide/oxygen binding (H-NOX) domain.
Proc.Natl.Acad.Sci.USA, 108, 2011
3TFA
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BU of 3tfa by Molmil
Crystal structure of an H-NOX protein from Nostoc sp. PCC 7120 under 6 atm of xenon
Descriptor: Alr2278 protein, PROTOPORPHYRIN IX CONTAINING FE, XENON
Authors:Winter, M.B, Herzik Jr, M.A, Kuriyan, J, Marletta, M.A.
Deposit date:2011-08-15
Release date:2011-11-09
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.2711 Å)
Cite:Tunnels modulate ligand flux in a heme nitric oxide/oxygen binding (H-NOX) domain.
Proc.Natl.Acad.Sci.USA, 108, 2011
3TF8
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BU of 3tf8 by Molmil
Crystal structure of an H-NOX protein from Nostoc sp. PCC 7120
Descriptor: Alr2278 protein, PROTOPORPHYRIN IX CONTAINING FE, SODIUM ION
Authors:Winter, M.B, Herzik Jr, M.A, Kuriyan, J, Marletta, M.A.
Deposit date:2011-08-15
Release date:2011-11-09
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.1302 Å)
Cite:Tunnels modulate ligand flux in a heme nitric oxide/oxygen binding (H-NOX) domain.
Proc.Natl.Acad.Sci.USA, 108, 2011
3U5Z
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BU of 3u5z by Molmil
Structure of T4 Bacteriophage clamp loader bound to the T4 clamp, primer-template DNA, and ATP analog
Descriptor: ADENOSINE-5'-DIPHOSPHATE, DNA polymerase accessory protein 44, DNA polymerase accessory protein 62, ...
Authors:Kelch, B.A, Makino, D.L, O'Donnell, M, Kuriyan, J.
Deposit date:2011-10-11
Release date:2012-01-04
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:How a DNA polymerase clamp loader opens a sliding clamp.
Science, 334, 2011
1XD4
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BU of 1xd4 by Molmil
Crystal structure of the DH-PH-cat module of Son of Sevenless (SOS)
Descriptor: Son of sevenless protein homolog 1
Authors:Sondermann, H, Soisson, S.M, Boykevisch, S, Yang, S.S, Bar-Sagi, D, Kuriyan, J.
Deposit date:2004-09-03
Release date:2004-11-02
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (3.64 Å)
Cite:Structural analysis of autoinhibition in the ras activator son of sevenless.
Cell(Cambridge,Mass.), 119, 2004
1XXH
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BU of 1xxh by Molmil
ATPgS Bound E. Coli Clamp Loader Complex
Descriptor: DNA polymerase III subunit gamma, DNA polymerase III, delta prime subunit, ...
Authors:Kazmirski, S.L, Podobnik, M, Weitze, T.F, O'Donnell, M, Kuriyan, J.
Deposit date:2004-11-05
Release date:2004-12-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.45 Å)
Cite:Structural analysis of the inactive state of the Escherichia coli DNA polymerase clamp-loader complex
Proc.Natl.Acad.Sci.USA, 101, 2004
3U60
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BU of 3u60 by Molmil
Structure of T4 Bacteriophage Clamp Loader Bound To Open Clamp, DNA and ATP Analog
Descriptor: ADENOSINE-5'-DIPHOSPHATE, DNA polymerase accessory protein 44, DNA polymerase accessory protein 62, ...
Authors:Kelch, B.A, Makino, D.L, O'Donnell, M, Kuriyan, J.
Deposit date:2011-10-11
Release date:2012-01-04
Method:X-RAY DIFFRACTION (3.34 Å)
Cite:How a DNA polymerase clamp loader opens a sliding clamp.
Science, 334, 2011
3TF9
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BU of 3tf9 by Molmil
Crystal structure of an H-NOX protein from Nostoc sp. PCC 7120 under 1 atm of xenon
Descriptor: Alr2278 protein, PROTOPORPHYRIN IX CONTAINING FE, SODIUM ION, ...
Authors:Winter, M.B, Herzik Jr, M.A, Kuriyan, J, Marletta, M.A.
Deposit date:2011-08-15
Release date:2011-11-09
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.5901 Å)
Cite:Tunnels modulate ligand flux in a heme nitric oxide/oxygen binding (H-NOX) domain.
Proc.Natl.Acad.Sci.USA, 108, 2011

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