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7XMA
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BU of 7xma by Molmil
Crystal structure of Bovine heart cytochrome c oxidase, apo structure with DMSO
Descriptor: (1R)-2-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL (11E)-OCTADEC-11-ENOATE, (1S)-2-{[(2-AMINOETHOXY)(HYDROXY)PHOSPHORYL]OXY}-1-[(STEAROYLOXY)METHYL]ETHYL (5E,8E,11E,14E)-ICOSA-5,8,11,14-TETRAENOATE, (7R,17E,20E)-4-HYDROXY-N,N,N-TRIMETHYL-9-OXO-7-[(PALMITOYLOXY)METHYL]-3,5,8-TRIOXA-4-PHOSPHAHEXACOSA-17,20-DIEN-1-AMINIUM 4-OXIDE, ...
Authors:Nishida, Y, Shinzawa-Itoh, K, Mizuno, N, Kumasaka, T, Yoshikawa, S, Tsukihara, T, Takashima, S, Shintani, Y.
Deposit date:2022-04-25
Release date:2022-12-21
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Identifying antibiotics based on structural differences in the conserved allostery from mitochondrial heme-copper oxidases.
Nat Commun, 13, 2022
7XMB
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BU of 7xmb by Molmil
Crystal structure of Bovine heart cytochrome c oxidase, the structure complexed with an allosteric inhibitor T113
Descriptor: (1R)-2-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL (11E)-OCTADEC-11-ENOATE, (1S)-2-{[(2-AMINOETHOXY)(HYDROXY)PHOSPHORYL]OXY}-1-[(STEAROYLOXY)METHYL]ETHYL (5E,8E,11E,14E)-ICOSA-5,8,11,14-TETRAENOATE, (7R,17E,20E)-4-HYDROXY-N,N,N-TRIMETHYL-9-OXO-7-[(PALMITOYLOXY)METHYL]-3,5,8-TRIOXA-4-PHOSPHAHEXACOSA-17,20-DIEN-1-AMINIUM 4-OXIDE, ...
Authors:Nishida, Y, Shinzawa-Itoh, K, Mizuno, N, Kumasaka, T, Yoshikawa, S, Tsukihara, T, Shintani, Y, Takashima, S.
Deposit date:2022-04-25
Release date:2022-12-21
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Identifying antibiotics based on structural differences in the conserved allostery from mitochondrial heme-copper oxidases.
Nat Commun, 13, 2022
1C4E
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BU of 1c4e by Molmil
GURMARIN FROM GYMNEMA SYLVESTRE
Descriptor: PROTEIN (GURMARIN)
Authors:Fletcher, J.I, Dingley, A.J, King, G.F.
Deposit date:1999-07-27
Release date:1999-08-27
Last modified:2023-12-27
Method:SOLUTION NMR
Cite:High-resolution solution structure of gurmarin, a sweet-taste-suppressing plant polypeptide.
Eur.J.Biochem., 264, 1999
5JTF
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BU of 5jtf by Molmil
Crystal structure of ArsN N-acetyltransferase from Pseudomonas putida KT2440
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Putative Phosphinothricin N-acetyltransferase
Authors:Venkadesh, S, Dheeman, D.S, Kandavelu, P, Rosen, B.P.
Deposit date:2016-05-09
Release date:2017-05-17
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.156 Å)
Cite:Arsinothricin, an arsenic-containing non-proteinogenic amino acid analog of glutamate, is a broad-spectrum antibiotic.
Commun Biol, 2, 2019
1ERZ
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BU of 1erz by Molmil
CRYSTAL STRUCTURE OF N-CARBAMYL-D-AMINO ACID AMIDOHYDROLASE WITH A NOVEL CATALYTIC FRAMEWORK COMMON TO AMIDOHYDROLASES
Descriptor: N-CARBAMYL-D-AMINO ACID AMIDOHYDROLASE
Authors:Nakai, T, Hasegawa, T, Yamashita, E, Yamamoto, M, Kumasaka, T, Ueki, T, Nanba, H, Ikenaka, Y, Takahashi, S, Sato, M, Tsukihara, T.
Deposit date:2000-04-06
Release date:2001-04-06
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal structure of N-carbamyl-D-amino acid amidohydrolase with a novel catalytic framework common to amidohydrolases.
Structure Fold.Des., 8, 2000
6OYH
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BU of 6oyh by Molmil
Crystal structure of MraY bound to carbacaprazamycin
Descriptor: (5S)-5'-O-(5-amino-5-deoxy-beta-D-ribofuranosyl)-5'-C-[(2S,5S,6S)-5-carboxy-6-heptadecyl-1,4-dimethyl-3-oxo-1,4-diazepan-2-yl]uridine, MraYAA nanobody, Phospho-N-acetylmuramoyl-pentapeptide-transferase
Authors:Mashalidis, E.H, Lee, S.Y.
Deposit date:2019-05-14
Release date:2019-07-10
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:Chemical logic of MraY inhibition by antibacterial nucleoside natural products.
Nat Commun, 10, 2019
6OYZ
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BU of 6oyz by Molmil
Crystal structure of MraY bound to capuramycin
Descriptor: (2~{S},3~{S},4~{S})-2-[(1~{R})-2-azanyl-1-[(2~{S},3~{S},4~{R},5~{R})-5-[2,4-bis(oxidanylidene)pyrimidin-1-yl]-3-methoxy-4-oxidanyl-oxolan-2-yl]-2-oxidanylidene-ethoxy]-3,4-bis(oxidanyl)-~{N}-[(3~{S})-2-oxidanylideneazepan-3-yl]-3,4-dihydro-2~{H}-pyran-6-carboxamide, MraYAA nanobody, Phospho-N-acetylmuramoyl-pentapeptide-transferase
Authors:Mashalidis, E.H, Lee, S.Y.
Deposit date:2019-05-15
Release date:2019-07-10
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3.62 Å)
Cite:Chemical logic of MraY inhibition by antibacterial nucleoside natural products.
Nat Commun, 10, 2019
6OZ6
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BU of 6oz6 by Molmil
Crystal structure of MraY bound to 3'-hydroxymureidomycin A
Descriptor: (2~{S})-2-[[(2~{S})-1-[[(2~{S},3~{S})-3-[[(2~{S})-2-azanyl-3-(3-hydroxyphenyl)propanoyl]-methyl-amino]-1-[[(~{Z})-[(3~{S},4~{R},5~{R})-5-[2,4-bis(oxidanylidene)pyrimidin-1-yl]-3,4-bis(oxidanyl)oxolan-2-ylidene]methyl]amino]-1-oxidanylidene-butan-2-yl]amino]-4-methylsulfanyl-1-oxidanylidene-butan-2-yl]carbamoylamino]-3-(3-hydroxyphenyl)propanoic acid, MraYAA nanobody, Phospho-N-acetylmuramoyl-pentapeptide-transferase
Authors:Mashalidis, E.H, Lee, S.Y.
Deposit date:2019-05-15
Release date:2019-07-10
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3.7 Å)
Cite:Chemical logic of MraY inhibition by antibacterial nucleoside natural products.
Nat Commun, 10, 2019
2YZA
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BU of 2yza by Molmil
Crystal structure of kinase domain of Human 5'-AMP-activated protein kinase alpha-2 subunit mutant (T172D)
Descriptor: 5'-AMP-activated protein kinase catalytic subunit alpha-2
Authors:Saijo, S, Takagi, T, Yoshikawa, S, Kishishita, S, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2007-05-04
Release date:2008-05-06
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (3.02 Å)
Cite:Structural basis for compound C inhibition of the human AMP-activated protein kinase alpha 2 subunit kinase domain
Acta Crystallogr.,Sect.D, 67, 2011
6JY3
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BU of 6jy3 by Molmil
Monomeric Form of Bovine Heart Cytochrome c Oxidase in the Fully Oxidized State
Descriptor: (1R)-2-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL (11E)-OCTADEC-11-ENOATE, (1S)-2-{[(2-AMINOETHOXY)(HYDROXY)PHOSPHORYL]OXY}-1-[(STEAROYLOXY)METHYL]ETHYL (5E,8E,11E,14E)-ICOSA-5,8,11,14-TETRAENOATE, (2S,3S,4S,5S,6R)-2-(2-decoxyethoxy)-6-(hydroxymethyl)oxane-3,4,5-triol, ...
Authors:Shinzawa-Itoh, K, Muramoto, K.
Deposit date:2019-04-26
Release date:2019-09-18
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Monomeric structure of an active form of bovine cytochromecoxidase.
Proc.Natl.Acad.Sci.USA, 116, 2019
6JY4
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BU of 6jy4 by Molmil
Monomeric Form of Bovine Heart Cytochrome c Oxidase in the Fully Reduced State
Descriptor: (1R)-2-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL (11E)-OCTADEC-11-ENOATE, (1S)-2-{[(2-AMINOETHOXY)(HYDROXY)PHOSPHORYL]OXY}-1-[(STEAROYLOXY)METHYL]ETHYL (5E,8E,11E,14E)-ICOSA-5,8,11,14-TETRAENOATE, (2S,3S,4S,5S,6R)-2-(2-decoxyethoxy)-6-(hydroxymethyl)oxane-3,4,5-triol, ...
Authors:Shinzawa-Itoh, K, Muramoto, K.
Deposit date:2019-04-26
Release date:2019-09-18
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Monomeric structure of an active form of bovine cytochromecoxidase.
Proc.Natl.Acad.Sci.USA, 116, 2019
5WPH
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BU of 5wph by Molmil
Crystal structure of ArsN, N-acetyltransferase with substrate AST from Pseudomonas putida KT2440
Descriptor: (2S)-2-amino-4-[hydroxy(methyl)arsoryl]butanoic acid, Phosphinothricin N-acetyltransferase, SODIUM ION
Authors:Venkadesh, S, Dheeman, D.S, Yoshinaga, M, Kandavelu, P, Rosen, B.P.
Deposit date:2017-08-04
Release date:2018-10-10
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.19 Å)
Cite:Arsinothricin, an arsenic-containing non-proteinogenic amino acid analog of glutamate, is a broad-spectrum antibiotic.
Commun Biol, 2, 2019
7VVR
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BU of 7vvr by Molmil
Bovine cytochrome c oxidese in CN-bound mixed valence state at 50 K
Descriptor: (1R)-2-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL (11E)-OCTADEC-11-ENOATE, (1S)-2-{[(2-AMINOETHOXY)(HYDROXY)PHOSPHORYL]OXY}-1-[(STEAROYLOXY)METHYL]ETHYL (5E,8E,11E,14E)-ICOSA-5,8,11,14-TETRAENOATE, (7R,17E,20E)-4-HYDROXY-N,N,N-TRIMETHYL-9-OXO-7-[(PALMITOYLOXY)METHYL]-3,5,8-TRIOXA-4-PHOSPHAHEXACOSA-17,20-DIEN-1-AMINIUM 4-OXIDE, ...
Authors:Shimada, A, Tsukihara, T.
Deposit date:2021-11-08
Release date:2022-11-16
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Crystallographic cyanide-probing for cytochrome c oxidase reveals structural bases suggesting that a putative proton transfer H-pathway pumps protons.
J.Biol.Chem., 299, 2023
7VUW
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BU of 7vuw by Molmil
Bovine heart cytochrome c oxidase in the cyanide-bound fully oxidized state at 50 K
Descriptor: (1R)-2-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL (11E)-OCTADEC-11-ENOATE, (1S)-2-{[(2-AMINOETHOXY)(HYDROXY)PHOSPHORYL]OXY}-1-[(STEAROYLOXY)METHYL]ETHYL (5E,8E,11E,14E)-ICOSA-5,8,11,14-TETRAENOATE, (7R,17E,20E)-4-HYDROXY-N,N,N-TRIMETHYL-9-OXO-7-[(PALMITOYLOXY)METHYL]-3,5,8-TRIOXA-4-PHOSPHAHEXACOSA-17,20-DIEN-1-AMINIUM 4-OXIDE, ...
Authors:Shimada, A, Tsukihara, T.
Deposit date:2021-11-04
Release date:2022-11-16
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Crystallographic cyanide-probing for cytochrome c oxidase reveals structural bases suggesting that a putative proton transfer H-pathway pumps protons.
J.Biol.Chem., 299, 2023
7W3E
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BU of 7w3e by Molmil
Bovine cytochrome c oxidese in CN-bound fully reduced state at 50 K
Descriptor: (1R)-2-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL (11E)-OCTADEC-11-ENOATE, (1S)-2-{[(2-AMINOETHOXY)(HYDROXY)PHOSPHORYL]OXY}-1-[(STEAROYLOXY)METHYL]ETHYL (5E,8E,11E,14E)-ICOSA-5,8,11,14-TETRAENOATE, (7R,17E,20E)-4-HYDROXY-N,N,N-TRIMETHYL-9-OXO-7-[(PALMITOYLOXY)METHYL]-3,5,8-TRIOXA-4-PHOSPHAHEXACOSA-17,20-DIEN-1-AMINIUM 4-OXIDE, ...
Authors:Tsukihara, T, Shimada, A.
Deposit date:2021-11-25
Release date:2022-12-07
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Crystallographic cyanide-probing for cytochrome c oxidase reveals structural bases suggesting that a putative proton transfer H-pathway pumps protons.
J.Biol.Chem., 299, 2023
6K84
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BU of 6k84 by Molmil
Structure of anti-prion RNA aptamer
Descriptor: RNA (25-MER)
Authors:Mashima, T, Lee, J.H, Hayashi, T, Nagata, T, Kinoshita, M, Katahira, M.
Deposit date:2019-06-11
Release date:2020-04-01
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Development and structural determination of an anti-PrPCaptamer that blocks pathological conformational conversion of prion protein.
Sci Rep, 10, 2020
1TBN
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BU of 1tbn by Molmil
NMR STRUCTURE OF A PROTEIN KINASE C-G PHORBOL-BINDING DOMAIN, MINIMIZED AVERAGE STRUCTURE
Descriptor: PROTEIN KINASE C, GAMMA TYPE, ZINC ION
Authors:Xu, R.X, Pawelczyk, T, Xia, T, Brown, S.C.
Deposit date:1997-04-15
Release date:1998-04-29
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:NMR structure of a protein kinase C-gamma phorbol-binding domain and study of protein-lipid micelle interactions.
Biochemistry, 36, 1997
2ZXT
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BU of 2zxt by Molmil
Crystal structure of Tim40/MIA40, a disulfide relay system in mitochondria, solved as MBP fusion protein
Descriptor: Maltose-binding periplasmic protein, LINKER, Mitochondrial intermembrane space import and assembly protein 40, ...
Authors:Kawano, S, Momose, T, Watanabe, N, Endo, T.
Deposit date:2009-01-07
Release date:2009-08-04
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural basis of yeast Tim40/Mia40 as an oxidative translocator in the mitochondrial intermembrane space.
Proc.Natl.Acad.Sci.USA, 106, 2009
3BOY
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BU of 3boy by Molmil
Crystal structure of the HutP antitermination complex bound to the HUT mRNA
Descriptor: 5'-R(*UP*UP*UP*AP*GP*UP*UP*UP*UP*UP*AP*GP*UP*UP*UP*UP*UP*AP*GP*UP*UP*U)-3', HISTIDINE, Hut operon positive regulatory protein, ...
Authors:Kumarevel, T.S, Balasundaresan, D, Jeyakanthan, J, Shinkai, A, Yokoyama, S, Kumar, P.K.R, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2007-12-18
Release date:2008-01-15
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal Structure of HutP complexed with the 55-mer RNA
To be Published
5YV5
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BU of 5yv5 by Molmil
Crystal structure of the complex of archaeal ribosomal stalk protein aP1 and archaeal ribosome recycling factor aABCE1.
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ATPase RIL, Archaeal ribosomal stalk protein aP1, ...
Authors:Imai, H, Abe, T, Miyoshi, T, Nishikawa, S, Ito, K, Uchiumi, T.
Deposit date:2017-11-24
Release date:2018-07-18
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:The ribosomal stalk protein is crucial for the action of the conserved ATPase ABCE1
Nucleic Acids Res., 46, 2018
3A3C
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BU of 3a3c by Molmil
Crystal structure of TIM40/MIA40 fusing MBP, C296S and C298S mutant
Descriptor: Maltose-binding periplasmic protein, LINKER, Mitochondrial intermembrane space import and assembly protein 40, ...
Authors:Kawano, S, Naoe, M, Momose, T, Watanabe, N, Endo, T.
Deposit date:2009-06-11
Release date:2009-08-04
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural basis of yeast Tim40/Mia40 as an oxidative translocator in the mitochondrial intermembrane space.
Proc.Natl.Acad.Sci.USA, 106, 2009
5Z84
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BU of 5z84 by Molmil
The structure of azide-bound cytochrome c oxidase determined using the crystals exposed to 20 mM azide solution for 4 days
Descriptor: (1R)-2-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL (11E)-OCTADEC-11-ENOATE, (1S)-2-{[(2-AMINOETHOXY)(HYDROXY)PHOSPHORYL]OXY}-1-[(STEAROYLOXY)METHYL]ETHYL (5E,8E,11E,14E)-ICOSA-5,8,11,14-TETRAENOATE, (7R,17E,20E)-4-HYDROXY-N,N,N-TRIMETHYL-9-OXO-7-[(PALMITOYLOXY)METHYL]-3,5,8-TRIOXA-4-PHOSPHAHEXACOSA-17,20-DIEN-1-AMINIUM 4-OXIDE, ...
Authors:Shimada, A, Hatano, K, Tadehara, H, Tsukihara, T.
Deposit date:2018-01-31
Release date:2018-08-15
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:X-ray structural analyses of azide-bound cytochromecoxidases reveal that the H-pathway is critically important for the proton-pumping activity.
J. Biol. Chem., 293, 2018
5Z85
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BU of 5z85 by Molmil
The structure of azide-bound cytochrome c oxidase determined using the another batch crystals exposed to 20 mM azide solution for 2 days
Descriptor: (1R)-2-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL (11E)-OCTADEC-11-ENOATE, (1S)-2-{[(2-AMINOETHOXY)(HYDROXY)PHOSPHORYL]OXY}-1-[(STEAROYLOXY)METHYL]ETHYL (5E,8E,11E,14E)-ICOSA-5,8,11,14-TETRAENOATE, (7R,17E,20E)-4-HYDROXY-N,N,N-TRIMETHYL-9-OXO-7-[(PALMITOYLOXY)METHYL]-3,5,8-TRIOXA-4-PHOSPHAHEXACOSA-17,20-DIEN-1-AMINIUM 4-OXIDE, ...
Authors:Shimada, A, Hatano, K, Tadehara, H, Tsukihara, T.
Deposit date:2018-01-31
Release date:2018-08-15
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:X-ray structural analyses of azide-bound cytochromecoxidases reveal that the H-pathway is critically important for the proton-pumping activity.
J. Biol. Chem., 293, 2018
8GVM
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BU of 8gvm by Molmil
The structure of azide-bound cytochrome C oxidase determined using the crystals exposed to 20 mm azide solution for 4 days
Descriptor: (1R)-2-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL (11E)-OCTADEC-11-ENOATE, (1S)-2-{[(2-AMINOETHOXY)(HYDROXY)PHOSPHORYL]OXY}-1-[(STEAROYLOXY)METHYL]ETHYL (5E,8E,11E,14E)-ICOSA-5,8,11,14-TETRAENOATE, (7R,17E,20E)-4-HYDROXY-N,N,N-TRIMETHYL-9-OXO-7-[(PALMITOYLOXY)METHYL]-3,5,8-TRIOXA-4-PHOSPHAHEXACOSA-17,20-DIEN-1-AMINIUM 4-OXIDE, ...
Authors:Tsukihara, T, Shimada, A.
Deposit date:2022-09-15
Release date:2022-10-19
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.851 Å)
Cite:X-ray structural analyses of azide-bound cytochromecoxidases reveal that the H-pathway is critically important for the proton-pumping activity
J. Biol. Chem., 293, 2018
6BW5
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BU of 6bw5 by Molmil
Human GPT (DPAGT1) in complex with tunicamycin
Descriptor: (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, Tunicamycin, UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase
Authors:Yoo, J, Kuk, A.C.Y, Mashalidis, E.H, Lee, S.-Y.
Deposit date:2017-12-14
Release date:2018-02-21
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:GlcNAc-1-P-transferase-tunicamycin complex structure reveals basis for inhibition of N-glycosylation.
Nat. Struct. Mol. Biol., 25, 2018

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