1A4Y
| RIBONUCLEASE INHIBITOR-ANGIOGENIN COMPLEX | Descriptor: | ANGIOGENIN, RIBONUCLEASE INHIBITOR | Authors: | Papageorgiou, A.C, Acharya, K.R. | Deposit date: | 1998-02-08 | Release date: | 1998-10-14 | Last modified: | 2023-08-02 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Molecular recognition of human angiogenin by placental ribonuclease inhibitor--an X-ray crystallographic study at 2.0 A resolution. EMBO J., 16, 1997
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1ABB
| CONTROL OF PHOSPHORYLASE B CONFORMATION BY A MODIFIED COFACTOR: CRYSTALLOGRAPHIC STUDIES ON R-STATE GLYCOGEN PHOSPHORYLASE RECONSTITUTED WITH PYRIDOXAL 5'-DIPHOSPHATE | Descriptor: | GLYCOGEN PHOSPHORYLASE B, INOSINIC ACID, PYRIDOXAL-5'-DIPHOSPHATE, ... | Authors: | Leonidas, D.D, Oikonomakos, N.G, Papageorgiou, A.C, Acharya, K.R, Barford, D, Johnson, L.N. | Deposit date: | 1992-04-09 | Release date: | 1993-10-31 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Control of phosphorylase b conformation by a modified cofactor: crystallographic studies on R-state glycogen phosphorylase reconstituted with pyridoxal 5'-diphosphate. Protein Sci., 1, 1992
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1AFL
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1B1J
| CRYSTAL STRUCTURE OF HUMAN ANGIOGENIN VARIANT H13A. | Descriptor: | HYDROLASE ANGIOGENIN | Authors: | Leonidas, D.D, Acharya, K.R. | Deposit date: | 1998-11-20 | Release date: | 1999-04-02 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Refined crystal structures of native human angiogenin and two active site variants: implications for the unique functional properties of an enzyme involved in neovascularisation during tumour growth. J.Mol.Biol., 285, 1999
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1B6V
| CRYSTAL STRUCTURE OF A HYBRID BETWEEN RIBONUCLEASE A AND BOVINE SEMINAL RIBONUCLEASE | Descriptor: | RIBONUCLEASE | Authors: | Vatzaki, E.H, Allen, S.C, Leonidas, D.D, Acharya, K.R. | Deposit date: | 1999-01-18 | Release date: | 1999-06-15 | Last modified: | 2023-08-02 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal structure of a hybrid between ribonuclease A and bovine seminal ribonuclease--the basic surface, at 2.0 A resolution. Eur.J.Biochem., 260, 1999
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1B1E
| CRYSTAL STRUCTURE OF HUMAN ANGIOGENIN VARIANT K40Q | Descriptor: | CITRIC ACID, HYDROLASE ANGIOGENIN | Authors: | Leonidas, D.D, Acharya, K.R. | Deposit date: | 1998-11-20 | Release date: | 1999-04-02 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Refined crystal structures of native human angiogenin and two active site variants: implications for the unique functional properties of an enzyme involved in neovascularisation during tumour growth. J.Mol.Biol., 285, 1999
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5NJL
| Cwp2 from Clostridium difficile | Descriptor: | Cell surface protein (Putative S-layer protein), SULFATE ION | Authors: | Bradshaw, W.J, Kirby, J.M, Roberts, A.K, Shone, C.C, Acharya, K.R. | Deposit date: | 2017-03-29 | Release date: | 2017-07-05 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Cwp2 from Clostridium difficile exhibits an extended three domain fold and cell adhesion in vitro. FEBS J., 284, 2017
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1B1I
| CRYSTAL STRUCTURE OF HUMAN ANGIOGENIN | Descriptor: | CITRIC ACID, HYDROLASE ANGIOGENIN | Authors: | Leonidas, D.D, Acharya, K.R. | Deposit date: | 1998-11-20 | Release date: | 1999-04-02 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Refined crystal structures of native human angiogenin and two active site variants: implications for the unique functional properties of an enzyme involved in neovascularisation during tumour growth. J.Mol.Biol., 285, 1999
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1B1Z
| STREPTOCOCCAL PYROGENIC EXOTOXIN A1 | Descriptor: | PROTEIN (TOXIN) | Authors: | Papageorgiou, A.C, Acharya, K.R. | Deposit date: | 1998-11-24 | Release date: | 1999-11-24 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.57 Å) | Cite: | Structural basis for the recognition of superantigen streptococcal pyrogenic exotoxin A (SpeA1) by MHC class II molecules and T-cell receptors. EMBO J., 18, 1999
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2PRJ
| Binding of N-acetyl-beta-D-glucopyranosylamine to Glycogen Phosphorylase B | Descriptor: | GLYCOGEN PHOSPHORYLASE, INOSINIC ACID, N-acetyl-beta-D-glucopyranosylamine, ... | Authors: | Oikonomakos, N.G, Kontou, M, Zographos, S.E, Watson, K.A, Johnson, L.N, Bichard, C.J.F, Fleet, G.W.J, Acharya, K.R. | Deposit date: | 1998-12-11 | Release date: | 1998-12-16 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | N-acetyl-beta-D-glucopyranosylamine: a potent T-state inhibitor of glycogen phosphorylase. A comparison with alpha-D-glucose. Protein Sci., 4, 1995
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1BKZ
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5OQ3
| High resolution structure of the functional region of Cwp19 from Clostridium difficile | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, Cwp19, ... | Authors: | Bradshaw, W.J, Kirby, J.M, Roberts, A.K, Shone, C.C, Acharya, K.R. | Deposit date: | 2017-08-10 | Release date: | 2017-11-01 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.35 Å) | Cite: | The molecular structure of the glycoside hydrolase domain of Cwp19 from Clostridium difficile. FEBS J., 284, 2017
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5OQ2
| Se-SAD structure of the functional region of Cwp19 from Clostridium difficile | Descriptor: | 1,2-ETHANEDIOL, Cwp19, PHOSPHATE ION | Authors: | Bradshaw, W.J, Kirby, J.M, Roberts, A.K, Shone, C.C, Acharya, K.R. | Deposit date: | 2017-08-10 | Release date: | 2017-11-01 | Last modified: | 2017-12-27 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | The molecular structure of the glycoside hydrolase domain of Cwp19 from Clostridium difficile. FEBS J., 284, 2017
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1C5D
| THE CRYSTAL STRUCTURE OF THE FAB FRAGMENT OF A RAT MONOCLONAL ANTIBODY AGAINST THE MAIN IMMUNOGENIC REGION OF THE HUMAN MUSCLE ACETYLCHOLINE RECEPTOR | Descriptor: | MONOCLONAL ANTIBODY AGAINST THE MAIN IMMUNOGENIC REGION OF THE HUMAN MUSCLE ACETYLCHOLINE RECEPTOR | Authors: | Kontou, M, Leonidas, D.D, Vatzaki, E.H, Tsantili, P, Mamalaki, A, Oikonomakos, N.G, Acharya, K.R, Tzartos, S.J. | Deposit date: | 1999-11-17 | Release date: | 1999-12-03 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | The crystal structure of the Fab fragment of a rat monoclonal antibody against the main immunogenic region of the human muscle acetylcholine receptor. Eur.J.Biochem., 267, 2000
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2R3Z
| Crystal structure of mouse IP-10 | Descriptor: | Small-inducible cytokine B10 | Authors: | Jabeen, T, Leonard, P, Jamaluddin, H, Acharya, K.R. | Deposit date: | 2007-08-30 | Release date: | 2008-08-12 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structure of mouse IP-10, a chemokine Acta Crystallogr.,Sect.D, 64, 2008
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2SKE
| PYRIDOXAL PHOSPHORYLASE B IN COMPLEX WITH PHOSPHITE, GLUCOSE AND INOSINE-5'-MONOPHOSPHATE | Descriptor: | INOSINIC ACID, PHOSPHITE ION, PYRIDOXAL PHOSPHORYLASE B, ... | Authors: | Oikonomakos, N.G, Zographos, S.E, Tsitsanou, K.E, Johnson, L.N, Acharya, K.R. | Deposit date: | 1998-12-11 | Release date: | 1998-12-16 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.46 Å) | Cite: | Activator anion binding site in pyridoxal phosphorylase b: the binding of phosphite, phosphate, and fluorophosphate in the crystal. Protein Sci., 5, 1996
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2SKC
| PYRIDOXAL PHOSPHORYLASE B IN COMPLEX WITH FLUOROPHOSPHATE, GLUCOSE AND INOSINE-5'-MONOPHOSPHATE | Descriptor: | FLUORO-PHOSPHITE ION, INOSINIC ACID, PYRIDOXAL PHOSPHORYLASE B, ... | Authors: | Oikonomakos, N.G, Zographos, S.E, Tsitsanou, K.E, Johnson, L.N, Acharya, K.R. | Deposit date: | 1998-12-11 | Release date: | 1998-12-16 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Activator anion binding site in pyridoxal phosphorylase b: the binding of phosphite, phosphate, and fluorophosphate in the crystal. Protein Sci., 5, 1996
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2SKD
| PYRIDOXAL PHOSPHORYLASE B IN COMPLEX WITH PHOSPHATE, GLUCOSE AND INOSINE-5'-MONOPHOSPHATE | Descriptor: | INOSINIC ACID, PHOSPHATE ION, PYRIDOXAL PHOSPHORYLASE B, ... | Authors: | Oikonomakos, N.G, Zographos, S.E, Tsitsanou, K.E, Johnson, L.N, Acharya, K.R. | Deposit date: | 1998-12-11 | Release date: | 1998-12-16 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Activator anion binding site in pyridoxal phosphorylase b: the binding of phosphite, phosphate, and fluorophosphate in the crystal. Protein Sci., 5, 1996
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2VFZ
| CRYSTAL STRUCTURE OF ALPHA-1,3 GALACTOSYLTRANSFERASE (R365K) IN COMPLEX WITH UDP-2F-GALACTOSE | Descriptor: | MANGANESE (II) ION, N-ACETYLLACTOSAMINIDE ALPHA-1,3-GALACTOSYL TRANSFERASE, URIDINE-5'-DIPHOSPHATE-2-DEOXY-2-FLUOROGALACTOSE | Authors: | Jamaluddin, H, Tumbale, P, Withers, S.G, Acharya, K.R, Brew, K. | Deposit date: | 2007-11-06 | Release date: | 2007-11-13 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Conformational Changes Induced by Binding Udp-2F-Galactose to Alpha-1,3 Galactosyltransferase-Implications for Catalysis J.Mol.Biol., 369, 2007
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2VXM
| Screening a Limited Structure-based Library Identifies UDP-GalNAc- Specific Mutants of alpha-1,3 Galactosyltransferase | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, GLYCEROL, N-ACETYLLACTOSAMINIDE ALPHA-1,3-GALACTOSYLTRANSFERASE | Authors: | Tumbale, P, Jamaluddin, H, Thiyagarajan, N, Acharya, K.R, Brew, K. | Deposit date: | 2008-07-07 | Release date: | 2008-09-23 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.82 Å) | Cite: | Screening a Limited Structure-Based Library Identifies Udp-Galnac-Specific Mutants of {Alpha}-1,3-Galactosyltransferase. Glycobiology, 18, 2008
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2VWE
| Crystal Structure of Vascular Endothelial Growth Factor-B in Complex with a Neutralizing Antibody Fab Fragment | Descriptor: | ANTI-VEGF-B MONOCLONAL ANTIBODY, VASCULAR ENDOTHELIAL GROWTH FACTOR B | Authors: | Leonard, P, Scotney, P.D, Jabeen, T, Iyer, S, Fabri, L.J, Nash, A.D, Acharya, K.R. | Deposit date: | 2008-06-23 | Release date: | 2008-11-04 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (3.4 Å) | Cite: | Crystal Structure of Vascular Endothelial Growth Factor-B in Complex with a Neutralising Antibody Fab Fragment. J.Mol.Biol., 384, 2008
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2VXL
| Screening a Limited Structure-based Library Identifies UDP-GalNAc- Specific Mutants of alpha-1,3 Galactosyltransferase | Descriptor: | MANGANESE (II) ION, N-ACETYLLACTOSAMINIDE ALPHA-1,3-GALACTOSYLTRANSFERASE, URIDINE-5'-DIPHOSPHATE | Authors: | Tumbale, P, Jamaluddin, H, Thiyagarajan, N, Acharya, K.R, Brew, K. | Deposit date: | 2008-07-07 | Release date: | 2008-09-23 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Screening a Limited Structure-Based Library Identifies Udp-Galnac-Specific Mutants of {Alpha}-1,3-Galactosyltransferase. Glycobiology, 18, 2008
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2VS3
| THE BINDING OF UDP-GALACTOSE BY AN ACTIVE SITE MUTANT OF alpha-1,3 GALACTOSYLTRANSFERASE (alpha3GT) | Descriptor: | MANGANESE (II) ION, N-ACETYLLACTOSAMINIDE ALPHA-1,3-GALACTOSYLTRANSFERASE, URIDINE-5'-DIPHOSPHATE, ... | Authors: | Tumbale, P, Jamaluddin, H, Thiyagarajan, N, Brew, K, Acharya, K.R. | Deposit date: | 2008-04-18 | Release date: | 2008-07-15 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structural Basis of Udp-Galactose Binding by Alpha- 1,3-Galactosyltransferase (Alpha3Gt): Role of Negative Charge on Aspartic Acid 316 in Structure and Activity. Biochemistry, 47, 2008
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1G86
| CHARCOT-LEYDEN CRYSTAL PROTEIN/N-ETHYLMALEIMIDE COMPLEX | Descriptor: | CHARCOT-LEYDEN CRYSTAL PROTEIN, N-ETHYLMALEIMIDE | Authors: | Ackerman, S.J, Liu, L, Kwatia, M.A, Savage, M.P, Leonidas, D.D, Swaminathan, G.J, Acharya, K.R. | Deposit date: | 2000-11-16 | Release date: | 2002-06-19 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Charcot-Leyden crystal protein (galectin-10) is not a dual function galectin with lysophospholipase activity but binds a lysophospholipase inhibitor in a novel structural fashion. J.Biol.Chem., 277, 2002
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1HFY
| ALPHA-LACTALBUMIN | Descriptor: | ALPHA-LACTALBUMIN, CALCIUM ION | Authors: | Pike, A.C.W, Brew, K, Acharya, K.R. | Deposit date: | 1996-06-13 | Release date: | 1997-07-07 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Crystal structures of guinea-pig, goat and bovine alpha-lactalbumin highlight the enhanced conformational flexibility of regions that are significant for its action in lactose synthase. Structure, 4, 1996
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