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7W2G
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BU of 7w2g by Molmil
An open-like conformation of the sigma-1 receptor from Xenopus laevis complexed with PRE084 by soaking
Descriptor: 2-morpholin-4-ylethyl 1-phenylcyclohexane-1-carboxylate, Sigma non-opioid intracellular receptor 1, octyl beta-D-glucopyranoside
Authors:Meng, F, Sun, Z, Zhou, X.
Deposit date:2021-11-23
Release date:2022-03-16
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.851 Å)
Cite:An open-like conformation of the sigma-1 receptor reveals its ligand entry pathway.
Nat Commun, 13, 2022
7W2H
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BU of 7w2h by Molmil
A double cysteine variant of the sigma-1 receptor from Xenopus laevis complexed with S1RA
Descriptor: 4-[2-(5-methyl-1-naphthalen-2-yl-pyrazol-3-yl)oxyethyl]morpholine, Sigma non-opioid intracellular receptor 1
Authors:Meng, F, Sun, Z, Zhou, X.
Deposit date:2021-11-23
Release date:2022-03-16
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (3.796 Å)
Cite:An open-like conformation of the sigma-1 receptor reveals its ligand entry pathway.
Nat Commun, 13, 2022
7W2D
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BU of 7w2d by Molmil
The closed conformation of the sigma-1 receptor from Xenopus laevis complexed with S1RA
Descriptor: 4-[2-(5-methyl-1-naphthalen-2-yl-pyrazol-3-yl)oxyethyl]morpholine, GOLD ION, Sigma non-opioid intracellular receptor 1
Authors:Meng, F, Sun, Z, Zhou, X.
Deposit date:2021-11-23
Release date:2022-03-16
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (3.471 Å)
Cite:An open-like conformation of the sigma-1 receptor reveals its ligand entry pathway.
Nat Commun, 13, 2022
7W2F
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BU of 7w2f by Molmil
An open-like conformation of the sigma-1 receptor from Xenopus laevis complexed with PRE084 by co-crystallization
Descriptor: 2-morpholin-4-ylethyl 1-phenylcyclohexane-1-carboxylate, Sigma non-opioid intracellular receptor 1, octyl beta-D-glucopyranoside
Authors:Meng, F, Sun, Z, Zhou, X.
Deposit date:2021-11-23
Release date:2022-03-16
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:An open-like conformation of the sigma-1 receptor reveals its ligand entry pathway.
Nat Commun, 13, 2022
7D5I
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BU of 7d5i by Molmil
Structure of Mycobacterium smegmatis bd complex in the apo-form.
Descriptor: CIS-HEME D HYDROXYCHLORIN GAMMA-SPIROLACTONE, Cytochrome D ubiquinol oxidase subunit 1, HEME B/C, ...
Authors:Wang, W, Gong, H, Gao, Y, Zhou, X, Rao, Z.
Deposit date:2020-09-26
Release date:2021-06-23
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (2.79 Å)
Cite:Cryo-EM structure of mycobacterial cytochrome bd reveals two oxygen access channels.
Nat Commun, 12, 2021
8JIX
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BU of 8jix by Molmil
Crystal structure of the Bagaza virus helicase and structure-based discovery of a novel inhibitor
Descriptor: Genome polyprotein
Authors:Zhao, R, Shu, W, Cao, J.M, Zhou, X, Wang, D.P.
Deposit date:2023-05-29
Release date:2024-03-06
Method:X-RAY DIFFRACTION (1.71 Å)
Cite:Crystal structure of the Bagaza virus helicase and structure-based discovery of a novel inhibitor
To Be Published
8JED
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BU of 8jed by Molmil
Crystal structure of mRNA cap (guanine-N7) methyltransferase E12 subunit from monkeypox virus and discovery of its inhibitors
Descriptor: mRNA-capping enzyme regulatory subunit OPG124
Authors:Wang, D, Zhao, R, Shu, W, Hu, W, Wang, M, Cao, J, Zhou, X.
Deposit date:2023-05-15
Release date:2023-12-06
Method:X-RAY DIFFRACTION (2.16 Å)
Cite:Crystal structure of mRNA cap (guanine-N7) methyltransferase E12 subunit from monkeypox virus and discovery of its inhibitors.
Int.J.Biol.Macromol., 253, 2023
7F5X
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BU of 7f5x by Molmil
GK domain of Drosophila P5CS filament with glutamate
Descriptor: Delta-1-pyrroline-5-carboxylate synthase, GAMMA-L-GLUTAMIC ACID
Authors:Liu, J.L, Zhong, J, Guo, C.J, Zhou, X.
Deposit date:2021-06-23
Release date:2022-04-06
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Structural basis of dynamic P5CS filaments.
Elife, 11, 2022
7F5V
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BU of 7f5v by Molmil
Drosophila P5CS filament with glutamate, ATP, and NADPH
Descriptor: Delta-1-pyrroline-5-carboxylate synthase
Authors:Liu, J.L, Zhong, J, Guo, C.J, Zhou, X.
Deposit date:2021-06-22
Release date:2022-04-06
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Structural basis of dynamic P5CS filaments.
Elife, 11, 2022
7F5U
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BU of 7f5u by Molmil
Drosophila P5CS filament with glutamate and ATPgammaS
Descriptor: Delta-1-pyrroline-5-carboxylate synthase
Authors:Liu, J.L, Zhong, J, Guo, C.J, Zhou, X.
Deposit date:2021-06-22
Release date:2022-04-06
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:Structural basis of dynamic P5CS filaments.
Elife, 11, 2022
7F5T
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BU of 7f5t by Molmil
Drosophila P5CS filament with glutamate
Descriptor: Delta-1-pyrroline-5-carboxylate synthase, GLUTAMIC ACID
Authors:Liu, J.L, Zhong, J, Guo, C.J, Zhou, X.
Deposit date:2021-06-22
Release date:2022-05-18
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:Structural basis of dynamic P5CS filaments.
Elife, 11, 2022
7Y96
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BU of 7y96 by Molmil
Crystal structure of the carboxy-terminal domain of a coronavirus M protein fused with a split GFP
Descriptor: Green fluorescent protein,Membrane protein
Authors:Wang, X, Sun, Z, Zhou, X.
Deposit date:2022-06-24
Release date:2022-08-17
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (3.415 Å)
Cite:Crystal structure of the membrane (M) protein from a bat betacoronavirus.
Pnas Nexus, 2, 2023
7Y9B
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BU of 7y9b by Molmil
Crystal structure of the membrane (M) protein of a SARS-COV-2-related coronavirus
Descriptor: 3,6,9,12,15-PENTAOXATRICOSAN-1-OL, Membrane protein
Authors:Wang, X, Sun, Z, Zhou, X.
Deposit date:2022-06-24
Release date:2022-08-17
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (3.214 Å)
Cite:Crystal structure of the membrane (M) protein from a bat betacoronavirus.
Pnas Nexus, 2, 2023
6LO8
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BU of 6lo8 by Molmil
Cryo-EM structure of the TIM22 complex from yeast
Descriptor: Mitochondrial import inner membrane translocase subunit TIM10, Mitochondrial import inner membrane translocase subunit TIM12, Mitochondrial import inner membrane translocase subunit TIM18, ...
Authors:Zhang, Y, Zhou, X, Wu, X, Li, L.
Deposit date:2020-01-04
Release date:2020-09-30
Last modified:2021-03-17
Method:ELECTRON MICROSCOPY (3.83 Å)
Cite:Structure of the mitochondrial TIM22 complex from yeast.
Cell Res., 31, 2021
6LUM
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BU of 6lum by Molmil
Structure of Mycobacterium smegmatis succinate dehydrogenase 2
Descriptor: (1S)-2-{[(2-AMINOETHOXY)(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL STEARATE, 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOINOSITOL, 2-(HEXADECANOYLOXY)-1-[(PHOSPHONOOXY)METHYL]ETHYL HEXADECANOATE, ...
Authors:Gao, Y, Gong, H, Zhou, X, Xiao, Y, Wang, W, Ji, W, Wang, Q, Rao, Z.
Deposit date:2020-01-29
Release date:2020-05-27
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (2.84 Å)
Cite:Cryo-EM structure of trimeric Mycobacterium smegmatis succinate dehydrogenase with a membrane-anchor SdhF.
Nat Commun, 11, 2020
6LGY
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BU of 6lgy by Molmil
Crystal structure of a cysteine-pair mutant (P10C-S291C) of a bacterial bile acid transporter in an inward-facing state complexed with glycine and sodium
Descriptor: 2,3-dihydroxypropyl (9Z)-octadec-9-enoate, GLYCINE, NONAETHYLENE GLYCOL, ...
Authors:Wang, X, Lyu, Y, Ji, Y, Sun, Z, Zhou, X.
Deposit date:2019-12-06
Release date:2020-12-09
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.247 Å)
Cite:Substrate binding in the bile acid transporter ASBT Yf from Yersinia frederiksenii.
Acta Crystallogr D Struct Biol, 77, 2021
6LH0
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BU of 6lh0 by Molmil
Crystal structure of a cysteine-pair mutant (P10C-S291C) of a bacterial bile acid transporter in an inward-facing apo-state
Descriptor: 2,3-dihydroxypropyl (9Z)-octadec-9-enoate, Transporter, sodium/bile acid symporter family
Authors:Wang, X, Lyu, Y, Ji, Y, Sun, Z, Zhou, X.
Deposit date:2019-12-06
Release date:2020-12-09
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.812 Å)
Cite:Substrate binding in the bile acid transporter ASBT Yf from Yersinia frederiksenii.
Acta Crystallogr D Struct Biol, 77, 2021
6LGZ
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BU of 6lgz by Molmil
Crystal structure of a cysteine-pair mutant (P10C-S291C) of a bacterial bile acid transporter in an inward-facing state complexed with sulfate
Descriptor: 2,3-dihydroxypropyl (9Z)-octadec-9-enoate, SULFATE ION, Transporter, ...
Authors:Wang, X, Lyu, Y, Ji, Y, Sun, Z, Zhou, X.
Deposit date:2019-12-06
Release date:2020-12-09
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.428 Å)
Cite:Substrate binding in the bile acid transporter ASBT Yf from Yersinia frederiksenii.
Acta Crystallogr D Struct Biol, 77, 2021
6LH1
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BU of 6lh1 by Molmil
Crystal structure of a cysteine-pair mutant (Y113C-P190C) of a bacterial bile acid transporter trapped in an outward-facing conformation
Descriptor: 2,3-dihydroxypropyl (9Z)-octadec-9-enoate, CITRIC ACID, Transporter, ...
Authors:Wang, X, Lyu, Y, Ji, Y, Sun, Z, Zhou, X.
Deposit date:2019-12-06
Release date:2020-12-09
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.861 Å)
Cite:An engineered disulfide bridge traps and validates an outward-facing conformation in a bile acid transporter.
Acta Crystallogr D Struct Biol, 77, 2021
6LGV
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BU of 6lgv by Molmil
Crystal structure of a cysteine-pair mutant (P10C-S291C) of a bacterial bile acid transporter in an inward-facing state complexed with citrate
Descriptor: 2,3-dihydroxypropyl (9Z)-octadec-9-enoate, CITRIC ACID, Transporter, ...
Authors:Wang, X, Lyu, Y, Ji, Y, Sun, Z, Zhou, X.
Deposit date:2019-12-06
Release date:2020-12-09
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.847 Å)
Cite:Substrate binding in the bile acid transporter ASBT Yf from Yersinia frederiksenii.
Acta Crystallogr D Struct Biol, 77, 2021
7CYG
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BU of 7cyg by Molmil
Crystal structure of a cysteine-pair mutant (Y113C-P190C) of a bacterial bile acid transporter before disulfide bond formation
Descriptor: Transporter, sodium/bile acid symporter family
Authors:Wang, X, Lyu, Y, Ji, Y, Sun, Z, Zhou, X.
Deposit date:2020-09-03
Release date:2021-01-13
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (3.198 Å)
Cite:An engineered disulfide bridge traps and validates an outward-facing conformation in a bile acid transporter.
Acta Crystallogr D Struct Biol, 77, 2021
7CYK
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BU of 7cyk by Molmil
Crystal structure of a second cysteine-pair mutant (V110C-I197C) of a bacterial bile acid transporter before disulfide bond formation
Descriptor: MERCURY (II) ION, Transporter, sodium/bile acid symporter family
Authors:Wang, X, Lyu, Y, Ji, Y, Sun, Z, Zhou, X.
Deposit date:2020-09-03
Release date:2021-01-13
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.785 Å)
Cite:An engineered disulfide bridge traps and validates an outward-facing conformation in a bile acid transporter.
Acta Crystallogr D Struct Biol, 77, 2021
7Y5G
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BU of 7y5g by Molmil
Cryo-EM structure of a eukaryotic ZnT8 in the presence of zinc
Descriptor: ZINC ION, Zinc transporter 8
Authors:Zhang, S, Fu, C, Luo, Y, Sun, Z, Su, Z, Zhou, X.
Deposit date:2022-06-17
Release date:2022-12-14
Last modified:2024-07-03
Method:ELECTRON MICROSCOPY (3.85 Å)
Cite:Cryo-EM structure of a eukaryotic zinc transporter at a low pH suggests its Zn 2+ -releasing mechanism.
J.Struct.Biol., 215, 2022
7Y5H
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BU of 7y5h by Molmil
Cryo-EM structure of a eukaryotic ZnT8 at a low pH
Descriptor: ZINC ION, Zinc transporter 8
Authors:Zhang, S, Fu, C, Luo, Y, Sun, Z, Su, Z, Zhou, X.
Deposit date:2022-06-17
Release date:2022-12-14
Last modified:2024-07-03
Method:ELECTRON MICROSCOPY (3.72 Å)
Cite:Cryo-EM structure of a eukaryotic zinc transporter at a low pH suggests its Zn 2+ -releasing mechanism.
J.Struct.Biol., 215, 2022
7WXI
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BU of 7wxi by Molmil
GPR domain of Drosophila P5CS filament with glutamate and ATPgammaS
Descriptor: Delta-1-pyrroline-5-carboxylate synthase, GAMMA-GLUTAMYL PHOSPHATE
Authors:Liu, J.L, Zhong, J, Guo, C.J, Zhou, X.
Deposit date:2022-02-14
Release date:2022-03-30
Last modified:2024-06-26
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Structural basis of dynamic P5CS filaments.
Elife, 11, 2022

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