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7WTC
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BU of 7wtc by Molmil
Cryo-EM structure of human pyruvate carboxylase with acetyl-CoA in the ground state
Descriptor: 5-(HEXAHYDRO-2-OXO-1H-THIENO[3,4-D]IMIDAZOL-6-YL)PENTANAL, ACETYL COENZYME *A, Pyruvate carboxylase, ...
Authors:Chai, P, Lan, P, Wu, J, Lei, M.
Deposit date:2022-02-04
Release date:2022-11-09
Last modified:2022-11-16
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Mechanistic insight into allosteric activation of human pyruvate carboxylase by acetyl-CoA.
Mol.Cell, 82, 2022
7WTB
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BU of 7wtb by Molmil
Cryo-EM structure of human pyruvate carboxylase with acetyl-CoA
Descriptor: 5-(HEXAHYDRO-2-OXO-1H-THIENO[3,4-D]IMIDAZOL-6-YL)PENTANAL, ACETYL COENZYME *A, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ...
Authors:Chai, P, Lan, P, Wu, J, Lei, M.
Deposit date:2022-02-04
Release date:2022-11-09
Last modified:2022-11-16
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Mechanistic insight into allosteric activation of human pyruvate carboxylase by acetyl-CoA.
Mol.Cell, 82, 2022
7X5C
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BU of 7x5c by Molmil
Solution structure of Tetrahymena p75OB1-p50PBM
Descriptor: Telomerase associated protein p50PBM, Telomerase-associated protein p75OB1
Authors:Wu, B, Tang, T, Xue, H.J, Wu, J, Lei, M.
Deposit date:2022-03-04
Release date:2022-10-19
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Association of the CST complex and p50 in Tetrahymena is crucial for telomere maintenance
Structure, 2022
5Y5A
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BU of 5y5a by Molmil
Crystal structure of Est1 and Cdc13
Descriptor: KLLA0F20702p, KLLA0F20922p
Authors:Chen, H, Xue, J, Wu, J, Lei, M.
Deposit date:2017-08-08
Release date:2017-12-20
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (2.206 Å)
Cite:Structural Insights into Yeast Telomerase Recruitment to Telomeres
Cell, 172, 2018
5Y58
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BU of 5y58 by Molmil
Crystal structure of Ku70/80 and TLC1
Descriptor: ATP-dependent DNA helicase II subunit 1, ATP-dependent DNA helicase II subunit 2, TLC1
Authors:Chen, H, Xue, J, Wu, J, Lei, M.
Deposit date:2017-08-08
Release date:2017-12-20
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural Insights into Yeast Telomerase Recruitment to Telomeres
Cell, 172, 2018
5Y59
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BU of 5y59 by Molmil
Crystal structure of Ku80 and Sir4
Descriptor: ATP-dependent DNA helicase II subunit 2, SULFATE ION, Sir4p
Authors:Chen, H, Xue, J, Wu, J, Lei, M.
Deposit date:2017-08-08
Release date:2017-12-20
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (2.402 Å)
Cite:Structural Insights into Yeast Telomerase Recruitment to Telomeres
Cell, 172, 2018
7X9G
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BU of 7x9g by Molmil
Crystal structure of human EDA and EDAR
Descriptor: Ectodysplasin-A, secreted form, Tumor necrosis factor receptor superfamily member EDAR
Authors:Yu, K, Wan, F, Huang, C, Wu, J, Lei, M.
Deposit date:2022-03-15
Release date:2023-02-22
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural insights into pathogenic mechanism of hypohidrotic ectodermal dysplasia caused by ectodysplasin A variants.
Nat Commun, 14, 2023
4V8P
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BU of 4v8p by Molmil
T.thermophila 60S ribosomal subunit in complex with initiation factor 6.
Descriptor: 26S RRNA, 5.8S RRNA, 5S RRNA, ...
Authors:Klinge, S, Voigts-Hoffmann, F, Leibundgut, M, Arpagaus, S, Ban, N.
Deposit date:2011-09-14
Release date:2014-07-09
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3.52 Å)
Cite:Crystal Structure of the Eukaryotic 60S Ribosomal Subunit in Complex with Initiation Factor 6.
Science, 334, 2011
7V99
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BU of 7v99 by Molmil
catalytic core of human telomerase holoenzyme
Descriptor: Histone H2A type 1-B/E, Histone H2B type 1-K, Primer DNA, ...
Authors:Wan, F, Ding, Y, Yang, L, Wu, Z, Wu, J, Lei, M.
Deposit date:2021-08-24
Release date:2022-03-30
Method:ELECTRON MICROSCOPY (3.54 Å)
Cite:Zipper head mechanism of telomere synthesis by human telomerase.
Cell Res., 31, 2021
7V9A
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BU of 7v9a by Molmil
biogenesis module of human telomerase holoenzyme
Descriptor: H/ACA ribonucleoprotein complex subunit 1, H/ACA ribonucleoprotein complex subunit 2, H/ACA ribonucleoprotein complex subunit 3, ...
Authors:Wan, F, Ding, Y, Yang, L, Wu, Z, Wu, J, Lei, M.
Deposit date:2021-08-24
Release date:2022-03-30
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (3.94 Å)
Cite:Zipper head mechanism of telomere synthesis by human telomerase.
Cell Res., 31, 2021
7C7A
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BU of 7c7a by Molmil
Cryo-EM structure of yeast Ribonuclease MRP with substrate ITS1
Descriptor: Internal Transcribed Spacer 1, MAGNESIUM ION, RNases MRP/P 32.9 kDa subunit, ...
Authors:Lan, P, Wu, J, Lei, M.
Deposit date:2020-05-24
Release date:2020-07-08
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Structural insight into precursor ribosomal RNA processing by ribonuclease MRP.
Science, 369, 2020
7C79
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BU of 7c79 by Molmil
Cryo-EM structure of yeast Ribonuclease MRP
Descriptor: MAGNESIUM ION, RNases MRP/P 32.9 kDa subunit, Ribonuclease MRP RNA subunit NME1, ...
Authors:Lan, P, Wu, J, Lei, M.
Deposit date:2020-05-24
Release date:2020-07-08
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (2.5 Å)
Cite:Structural insight into precursor ribosomal RNA processing by ribonuclease MRP.
Science, 369, 2020
6LI3
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BU of 6li3 by Molmil
cryo-EM structure of GPR52-miniGs-NB35
Descriptor: G-protein coupled receptor 52, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
Authors:Li, M, Wang, N, Xu, F, Wu, J, Lei, M.
Deposit date:2019-12-10
Release date:2020-02-26
Last modified:2020-03-18
Method:ELECTRON MICROSCOPY (3.32 Å)
Cite:Structural basis of ligand recognition and self-activation of orphan GPR52.
Nature, 579, 2020
6K0B
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BU of 6k0b by Molmil
cryo-EM structure of archaeal Ribonuclease P with mature tRNA
Descriptor: 50S ribosomal protein L7Ae, RPR, Ribonuclease P protein component 1, ...
Authors:Wan, F, Lan, P, Wu, J, Lei, M.
Deposit date:2019-05-05
Release date:2019-06-19
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (4.3 Å)
Cite:Cryo-electron microscopy structure of an archaeal ribonuclease P holoenzyme.
Nat Commun, 10, 2019
6K0A
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BU of 6k0a by Molmil
cryo-EM structure of an archaeal Ribonuclease P
Descriptor: 50S ribosomal protein L7Ae, RPR, Ribonuclease P protein component 1, ...
Authors:Wan, F, Lan, P, Wu, J, Lei, M.
Deposit date:2019-05-05
Release date:2019-06-19
Last modified:2022-12-21
Method:ELECTRON MICROSCOPY (4.6 Å)
Cite:Cryo-electron microscopy structure of an archaeal ribonuclease P holoenzyme.
Nat Commun, 10, 2019
7D58
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BU of 7d58 by Molmil
cryo-EM structure of human RNA polymerase III in elongating state
Descriptor: DNA-directed RNA polymerase III subunit RPC1, DNA-directed RNA polymerase III subunit RPC10, DNA-directed RNA polymerase III subunit RPC2, ...
Authors:Wang, Q, Wan, F, Lan, P, Wu, J, Lei, M.
Deposit date:2020-09-25
Release date:2021-02-17
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Structural insights into transcriptional regulation of human RNA polymerase III.
Nat.Struct.Mol.Biol., 28, 2021
7D59
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BU of 7d59 by Molmil
cryo-EM structure of human RNA polymerase III in apo state
Descriptor: DNA-directed RNA polymerase III subunit RPC1, DNA-directed RNA polymerase III subunit RPC10, DNA-directed RNA polymerase III subunit RPC2, ...
Authors:Wang, Q, Wan, F, Lan, P, Wu, J, Lei, M.
Deposit date:2020-09-25
Release date:2021-02-17
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structural insights into transcriptional regulation of human RNA polymerase III.
Nat.Struct.Mol.Biol., 28, 2021
7CUJ
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BU of 7cuj by Molmil
Crystal structure of fission yeast Ccq1 and Tpz1
Descriptor: Coiled-coil quantitatively-enriched protein 1, Protection of telomeres protein tpz1
Authors:Sun, H, Wu, Z, Wu, J, Lei, M.
Deposit date:2020-08-23
Release date:2021-08-25
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural insights into Pot1-ssDNA, Pot1-Tpz1 and Tpz1-Ccq1 Interactions within fission yeast shelterin complex.
Plos Genet., 18, 2022
7CUI
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BU of 7cui by Molmil
Crystal structure of fission yeast Pot1 and Tpz1
Descriptor: Protection of telomeres protein 1, Protection of telomeres protein tpz1, SULFATE ION
Authors:Sun, H, Wu, Z, Wu, J, Lei, M.
Deposit date:2020-08-23
Release date:2021-08-25
Last modified:2022-09-07
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural insights into Pot1-ssDNA, Pot1-Tpz1 and Tpz1-Ccq1 Interactions within fission yeast shelterin complex.
Plos Genet., 18, 2022
7CUH
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BU of 7cuh by Molmil
Crystal structure of fission yeast Pot1 and ssDNA
Descriptor: Protection of telomeres protein 1, Telomere single-strand DNA
Authors:Sun, H, Wu, Z, Wu, J, Lei, M.
Deposit date:2020-08-23
Release date:2021-08-25
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural insights into Pot1-ssDNA, Pot1-Tpz1 and Tpz1-Ccq1 Interactions within fission yeast shelterin complex.
Plos Genet., 18, 2022
6L7O
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BU of 6l7o by Molmil
cryo-EM structure of cyanobacteria Fd-NDH-1L complex
Descriptor: 1,2-DI-O-ACYL-3-O-[6-DEOXY-6-SULFO-ALPHA-D-GLUCOPYRANOSYL]-SN-GLYCEROL, 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, BETA-CAROTENE, ...
Authors:Zhang, C, Shuai, J, Wu, J, Lei, M.
Deposit date:2019-11-02
Release date:2020-02-19
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Structural insights into NDH-1 mediated cyclic electron transfer.
Nat Commun, 11, 2020
6LBS
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BU of 6lbs by Molmil
Crystal structure of yeast Stn1
Descriptor: KLLA0C11825p
Authors:Ge, Y, Wu, Z, Wu, J, Lei, M.
Deposit date:2019-11-14
Release date:2020-07-15
Last modified:2020-08-19
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural insights into telomere protection and homeostasis regulation by yeast CST complex.
Nat.Struct.Mol.Biol., 27, 2020
7E34
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BU of 7e34 by Molmil
Crystal structure of SUN1-Speedy A-CDK2
Descriptor: Cyclin-dependent kinase 2, GLYCEROL, SUN domain-containing protein 1, ...
Authors:Chen, Y, Huang, C, Wu, J, Lei, M.
Deposit date:2021-02-08
Release date:2021-04-14
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (3.19 Å)
Cite:The SUN1-SPDYA interaction plays an essential role in meiosis prophase I.
Nat Commun, 12, 2021
6LBR
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BU of 6lbr by Molmil
Crystal structure of yeast Cdc13 and ssDNA
Descriptor: KLLA0F20922p, Telomere single-strand DNA
Authors:Ge, Y, Wu, Z, Wu, J, Lei, M.
Deposit date:2019-11-14
Release date:2020-07-15
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural insights into telomere protection and homeostasis regulation by yeast CST complex.
Nat.Struct.Mol.Biol., 27, 2020
6LBT
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BU of 6lbt by Molmil
Crystal structure of yeast Cdc13 and Stn1
Descriptor: GLYCEROL, KLLA0C11825p, KLLA0F20922p,KLLA0F20922p
Authors:Ge, Y, Wu, Z, Wu, J, Lei, M.
Deposit date:2019-11-14
Release date:2020-07-15
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural insights into telomere protection and homeostasis regulation by yeast CST complex.
Nat.Struct.Mol.Biol., 27, 2020

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