6B46
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![BU of 6b46 by Molmil](/molmil-images/mine/6b46) | Cryo-EM structure of Type I-F CRISPR crRNA-guided Csy surveillance complex with bound anti-CRISPR protein AcrF1 | Descriptor: | Anti-CRISPR protein AcrF1, CRISPR-associated endonuclease Cas6/Csy4, CRISPR-associated protein Csy3, ... | Authors: | Guo, T.W, Bartesaghi, A, Yang, H, Falconieri, V, Rao, P, Merk, A, Fox, T, Earl, L, Patel, D.J, Subramaniam, S. | Deposit date: | 2017-09-25 | Release date: | 2017-10-18 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Cryo-EM Structures Reveal Mechanism and Inhibition of DNA Targeting by a CRISPR-Cas Surveillance Complex. Cell, 171, 2017
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8A5Q
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![BU of 8a5q by Molmil](/molmil-images/mine/8a5q) | Structure of Arp4-Ies4-N-actin-Arp8-Ino80HSA subcomplex (A-module) of Chaetomium thermophilum INO80 on straight DNA | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Actin, Actin related protein 4 (Arp4), ... | Authors: | Kunert, F, Metzner, F.J, Eustermann, S, Jung, J, Woike, S, Schall, K, Kostrewa, D, Hopfner, K.P. | Deposit date: | 2022-06-15 | Release date: | 2022-12-14 | Last modified: | 2022-12-28 | Method: | ELECTRON MICROSCOPY (3.15 Å) | Cite: | Structural mechanism of extranucleosomal DNA readout by the INO80 complex. Sci Adv, 8, 2022
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8A5P
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![BU of 8a5p by Molmil](/molmil-images/mine/8a5p) | Structure of Arp4-Ies4-N-actin-Arp8-Ino80HSA subcomplex (A-module) of Chaetomium thermophilum INO80 on curved DNA | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Actin, Actin related protein 4 (Arp4), ... | Authors: | Kunert, F, Metzner, F.J, Eustermann, S, Jung, J, Woike, S, Schall, K, Kostrewa, D, Hopfner, K.P. | Deposit date: | 2022-06-15 | Release date: | 2022-12-14 | Last modified: | 2022-12-28 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Structural mechanism of extranucleosomal DNA readout by the INO80 complex. Sci Adv, 8, 2022
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8A5A
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![BU of 8a5a by Molmil](/molmil-images/mine/8a5a) | Structure of Arp4-Ies4-N-actin-Arp8-Ino80HSA subcomplex (A-module) of INO80 | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Actin, Actin-like protein ARP8, ... | Authors: | Kunert, F, Metzner, F.J, Eustermann, S, Jung, J, Woike, S, Schall, K, Kostrewa, D, Hopfner, K.P. | Deposit date: | 2022-06-14 | Release date: | 2022-12-14 | Last modified: | 2023-03-01 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Structural mechanism of extranucleosomal DNA readout by the INO80 complex. Sci Adv, 8, 2022
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1MOJ
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![BU of 1moj by Molmil](/molmil-images/mine/1moj) | Crystal structure of an archaeal dps-homologue from Halobacterium salinarum | Descriptor: | Dps-like ferritin, FE (III) ION, MAGNESIUM ION, ... | Authors: | Zeth, K, Offermann, S, Essen, L.O, Oesterhelt, D. | Deposit date: | 2002-09-09 | Release date: | 2004-04-20 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Iron-oxo clusters biomineralizing on protein surfaces: Structural analysis of Halobacterium salinarum DpsA in its low- and high-iron states. Proc.Natl.Acad.Sci.USA, 101, 2004
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8A5O
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![BU of 8a5o by Molmil](/molmil-images/mine/8a5o) | Structure of Arp4-Ies4-N-actin-Arp8-Ino80HSA subcomplex (A-module) of S. cerevisiae INO80 | Descriptor: | Actin, Actin-like protein ARP8, Actin-related protein 4, ... | Authors: | Kunert, F, Metzner, F.J, Eustermann, S, Jung, J, Woike, S, Schall, K, Kostrewa, D, Hopfner, K.P. | Deposit date: | 2022-06-15 | Release date: | 2022-12-14 | Last modified: | 2022-12-28 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Structural mechanism of extranucleosomal DNA readout by the INO80 complex. Sci Adv, 8, 2022
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5IKM
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![BU of 5ikm by Molmil](/molmil-images/mine/5ikm) | 1.9 Angstrom Crystal Structure of NS5 Methyl Transferase from Dengue Virus 1 in Complex with S-Adenosylmethionine and Beta-D-Fructopyranose. | Descriptor: | CHLORIDE ION, D-MALATE, GLYCEROL, ... | Authors: | Minasov, G, Shuvalova, L, Winsor, J, Dubrovska, I, Flores, K, Shatsman, S, Kwon, K, Anderson, W.F, Center for Structural Genomics of Infectious Diseases, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2016-03-03 | Release date: | 2016-03-16 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | 1.9 Angstrom Crystal Structure of NS5 Methyl Transferase from Dengue Virus 1 in Complex with S-Adenosylmethionine and Beta-D-Fructopyranose. To Be Published
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5K6A
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![BU of 5k6a by Molmil](/molmil-images/mine/5k6a) | Trypanosoma brucei Pteridine reductase 1 (PTR1) in complex with compound 1 | Descriptor: | (2~{R})-2-(3-hydroxyphenyl)-6-oxidanyl-2,3-dihydrochromen-4-one, ACETATE ION, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | Authors: | Landi, G, Pozzi, C, Di Pisa, F, Dello lacono, L, Mangani, S. | Deposit date: | 2016-05-24 | Release date: | 2017-03-22 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Chroman-4-One Derivatives Targeting Pteridine Reductase 1 and Showing Anti-Parasitic Activity. Molecules, 22, 2017
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8A5D
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![BU of 8a5d by Molmil](/molmil-images/mine/8a5d) | Structure of Arp4-Ies4-N-actin-Arp8-Ino80HSA subcomplex (A-module) of Chaetomium thermophilum INO80 | Descriptor: | Actin, Actin related protein 4 (Arp4), Actin-related protein 8, ... | Authors: | Kunert, F, Metzner, F.J, Eustermann, S, Jung, J, Woike, S, Schall, K, Kostrewa, D, Hopfner, K.P. | Deposit date: | 2022-06-14 | Release date: | 2022-12-28 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Structural mechanism of extranucleosomal DNA readout by the INO80 complex. Sci Adv, 8, 2022
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1MLZ
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![BU of 1mlz by Molmil](/molmil-images/mine/1mlz) | Crystal Structure of 7,8-Diaminopelargonic Acid Synthase in complex with the trans-isomer of amiclenomycin. | Descriptor: | 7,8-diamino-pelargonic acid aminotransferase, PYRIDOXAL-5'-PHOSPHATE, SODIUM ION, ... | Authors: | Sandmark, J, Mann, S, Marquet, A, Schneider, G. | Deposit date: | 2002-09-02 | Release date: | 2002-12-04 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Structural basis for the inhibition of the biosynthesis of biotin by the antibiotic amiclenomycin J.Biol.Chem., 277, 2002
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8VKM
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![BU of 8vkm by Molmil](/molmil-images/mine/8vkm) | Cryo-EM structure of SARS-CoV-2 XBB.1.5 spike protein in complex with mouse ACE2 (conformation 1) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, ... | Authors: | Zhu, X, Mannar, D, Saville, J, Poloni, C, Bezeruk, A, Tidey, K, Ahmed, S, Tuttle, K, Vahdatihassani, F, Cholak, S, Cook, L, Steiner, T.S, Subramaniam, S. | Deposit date: | 2024-01-09 | Release date: | 2024-02-14 | Method: | ELECTRON MICROSCOPY (2.83 Å) | Cite: | SARS-CoV-2 XBB.1.5 Spike Protein: Altered Receptor Binding, Antibody Evasion, and Retention of T Cell Recognition To Be Published
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8VKO
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![BU of 8vko by Molmil](/molmil-images/mine/8vko) | Cryo-EM structure of SARS-CoV-2 XBB.1.5 spike protein in complex with human ACE2 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Processed angiotensin-converting enzyme 2, ... | Authors: | Zhu, X, Mannar, D, Saville, J, Poloni, C, Bezeruk, A, Tidey, K, Ahmed, S, Tuttle, K, Vahdatihassani, F, Cholak, S, Cook, L, Steiner, T.S, Subramaniam, S. | Deposit date: | 2024-01-09 | Release date: | 2024-02-14 | Method: | ELECTRON MICROSCOPY (2.68 Å) | Cite: | SARS-CoV-2 XBB.1.5 Spike Protein: Altered Receptor Binding, Antibody Evasion, and Retention of T Cell Recognition To Be Published
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5HFZ
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![BU of 5hfz by Molmil](/molmil-images/mine/5hfz) | Mmi1 YTH domain | Descriptor: | YTH domain-containing protein mmi1 | Authors: | Chatterjee, D, Goldgur, Y, Shuman, S. | Deposit date: | 2016-01-07 | Release date: | 2016-02-10 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (1.96 Å) | Cite: | Transcription of lncRNA prt, clustered prt RNA sites for Mmi1 binding, and RNA polymerase II CTD phospho-sites govern the repression of pho1 gene expression under phosphate-replete conditions in fission yeast. Rna, 22, 2016
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8VKN
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![BU of 8vkn by Molmil](/molmil-images/mine/8vkn) | Cryo-EM structure of SARS-CoV-2 XBB.1.5 spike protein in complex with mouse ACE2 (focused refinement of RBD and mouse ACE2) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, ... | Authors: | Zhu, X, Mannar, D, Saville, J, Poloni, C, Bezeruk, A, Tidey, K, Ahmed, S, Tuttle, K, Vahdatihassani, F, Cholak, S, Cook, L, Steiner, T.S, Subramaniam, S. | Deposit date: | 2024-01-09 | Release date: | 2024-02-14 | Method: | ELECTRON MICROSCOPY (2.93 Å) | Cite: | SARS-CoV-2 XBB.1.5 Spike Protein: Altered Receptor Binding, Antibody Evasion, and Retention of T Cell Recognition To Be Published
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8VKL
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![BU of 8vkl by Molmil](/molmil-images/mine/8vkl) | Cryo-EM structure of SARS-CoV-2 XBB.1.5 spike protein in complex with mouse ACE2 (conformation 2) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, ... | Authors: | Zhu, X, Mannar, D, Saville, J, Poloni, C, Bezeruk, A, Tidey, K, Ahmed, S, Tuttle, K, Vahdatihassani, F, Cholak, S, Cook, L, Steiner, T.S, Subramaniam, S. | Deposit date: | 2024-01-09 | Release date: | 2024-02-14 | Method: | ELECTRON MICROSCOPY (2.91 Å) | Cite: | SARS-CoV-2 XBB.1.5 Spike Protein: Altered Receptor Binding, Antibody Evasion, and Retention of T Cell Recognition To Be Published
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5H8A
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![BU of 5h8a by Molmil](/molmil-images/mine/5h8a) | Mmi1 YTH domain | Descriptor: | YTH domain-containing protein mmi1 | Authors: | Chatterjee, D, Goldgur, Y, Shuman, S. | Deposit date: | 2015-12-23 | Release date: | 2016-01-13 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (1.751 Å) | Cite: | Transcription of lncRNA prt, clustered prt RNA sites for Mmi1 binding, and RNA polymerase II CTD phospho-sites govern the repression of pho1 gene expression under phosphate-replete conditions in fission yeast. Rna, 22, 2016
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6B44
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![BU of 6b44 by Molmil](/molmil-images/mine/6b44) | Cryo-EM structure of Type I-F CRISPR crRNA-guided Csy surveillance complex with bound target dsDNA | Descriptor: | CRISPR-associated endonuclease Cas6/Csy4, CRISPR-associated protein Csy1, CRISPR-associated protein Csy2, ... | Authors: | Guo, T.W, Bartesaghi, A, Yang, H, Falconieri, V, Rao, P, Merk, A, Fox, T, Earl, L, Patel, D.J, Subramaniam, S. | Deposit date: | 2017-09-25 | Release date: | 2017-10-18 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Cryo-EM Structures Reveal Mechanism and Inhibition of DNA Targeting by a CRISPR-Cas Surveillance Complex. Cell, 171, 2017
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5JCX
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![BU of 5jcx by Molmil](/molmil-images/mine/5jcx) | Trypanosoma brucei PTR1 in complex with inhibitor NP-29 | Descriptor: | 3,5,7-trihydroxy-2-(2-hydroxyphenyl)-4H-1-benzopyran-4-one, ACETATE ION, GLYCEROL, ... | Authors: | Landi, G, Pozzi, C, Di Pisa, F, Dello Iacono, L, Mangani, S. | Deposit date: | 2016-04-15 | Release date: | 2016-08-17 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.43 Å) | Cite: | Profiling of Flavonol Derivatives for the Development of Antitrypanosomatidic Drugs. J.Med.Chem., 59, 2016
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5JDI
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![BU of 5jdi by Molmil](/molmil-images/mine/5jdi) | Trypanosoma brucei PTR1 in complex with cofactor and inhibitor NMT-H024 (compound 2) | Descriptor: | 3,6-dihydroxy-2-(3-hydroxyphenyl)-4H-1-benzopyran-4-one, ACETATE ION, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | Authors: | Landi, G, Pozzi, C, Di Pisa, F, Dello lacono, L, Mangani, S. | Deposit date: | 2016-04-16 | Release date: | 2016-08-17 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.38 Å) | Cite: | Profiling of Flavonol Derivatives for the Development of Antitrypanosomatidic Drugs. J.Med.Chem., 59, 2016
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5J93
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![BU of 5j93 by Molmil](/molmil-images/mine/5j93) | Five minutes iron loaded Rana Catesbeiana H' ferritin variant E57A/E136A/D140A | Descriptor: | CHLORIDE ION, FE (II) ION, Ferritin, ... | Authors: | Pozzi, C, Di Pisa, F, Mangani, S, Bernacchioni, C, Turano, P. | Deposit date: | 2016-04-08 | Release date: | 2016-10-05 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.1 Å) | Cite: | Ferroxidase Activity in Eukaryotic Ferritin is Controlled by Accessory-Iron-Binding Sites in the Catalytic Cavity. Chemistry, 22, 2016
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6SJT
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![BU of 6sjt by Molmil](/molmil-images/mine/6sjt) | |
5V5X
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![BU of 5v5x by Molmil](/molmil-images/mine/5v5x) | Protocadherin gammaB7 EC3-6 cis-dimer structure | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Goodman, K.M, Mannepalli, S, Bahna, F, Honig, B, Shapiro, L. | Deposit date: | 2017-03-15 | Release date: | 2017-11-01 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (3.5 Å) | Cite: | Protocadherin cis-dimer architecture and recognition unit diversity. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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6BLG
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![BU of 6blg by Molmil](/molmil-images/mine/6blg) | Crystal Structure of Sugar Transaminase from Klebsiella pneumoniae Complexed with PLP | Descriptor: | 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHLORIDE ION, ... | Authors: | Maltseva, N, Kim, Y, Shatsman, S, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2017-11-10 | Release date: | 2017-11-22 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.102 Å) | Cite: | Crystal Structure of Sugar Transaminase from Klebsiella pneumoniae Complexed with PLP To Be Published
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6AC7
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![BU of 6ac7 by Molmil](/molmil-images/mine/6ac7) | Structure of a (3+1) hybrid G-quadruplex in the PARP1 promoter | Descriptor: | 5'-D(*TP*GP*GP*GP*GP*TP*CP*CP*GP*AP*GP*GP*CP*GP*GP*GP*GP*CP*TP*TP*GP*GP*G)-3' | Authors: | Sengar, A, Vandana, J.J, Chambers, V.S, Di Antonio, M, Winnerdy, F.R, Balasubramanian, S, Phan, A.T. | Deposit date: | 2018-07-25 | Release date: | 2019-02-27 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Structure of a (3+1) hybrid G-quadruplex in the PARP1 promoter. Nucleic Acids Res., 47, 2019
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6SKW
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![BU of 6skw by Molmil](/molmil-images/mine/6skw) | Crystal structure of the Legionella pneumophila type II secretion system substrate NttE | Descriptor: | 1,2-ETHANEDIOL, NttE | Authors: | Portlock, T.J, Rehman, S, Garnett, J.A. | Deposit date: | 2019-08-16 | Release date: | 2020-05-20 | Last modified: | 2020-07-22 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structure, Dynamics and Cellular Insight Into Novel Substrates of theLegionella pneumophilaType II Secretion System. Front Mol Biosci, 7, 2020
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