1D1X
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![BU of 1d1x by Molmil](/molmil-images/mine/1d1x) | BOVINE ENDOTHELIAL NITRIC OXIDE SYNTHASE HEME DOMAIN COMPLEXED WITH 1,4-PBITU (H4B BOUND) | Descriptor: | 2-{2-[4-(2-CARBAMIMIDOYLSULFANYL-ETHYL)-PHENYL]-ETHYL}-ISOTHIOUREA, 5,6,7,8-TETRAHYDROBIOPTERIN, ACETATE ION, ... | Authors: | Raman, C.S, Li, H, Martasek, P, Southan, G.J, Masters, B.S.S, Poulos, T.L. | Deposit date: | 1999-09-21 | Release date: | 2001-07-25 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Implications for isoform-selective inhibitor design derived from the binding mode of bulky isothioureas to the heme domain of endothelial nitric-oxide synthase. J.Biol.Chem., 276, 2001
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1D1V
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![BU of 1d1v by Molmil](/molmil-images/mine/1d1v) | BOVINE ENDOTHELIAL NITRIC OXIDE SYNTHASE HEME DOMAIN COMPLEXED WITH S-ETHYL-N-PHENYL-ISOTHIOUREA (H4B BOUND) | Descriptor: | 2-ETHYL-1-PHENYL-ISOTHIOUREA, 5,6,7,8-TETRAHYDROBIOPTERIN, ACETATE ION, ... | Authors: | Raman, C.S, Li, H, Martasek, P, Southan, G.J, Masters, B.S.S, Poulos, T.L. | Deposit date: | 1999-09-21 | Release date: | 2001-07-25 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.93 Å) | Cite: | Implications for isoform-selective inhibitor design derived from the binding mode of bulky isothioureas to the heme domain of endothelial nitric-oxide synthase. J.Biol.Chem., 276, 2001
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2QMW
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![BU of 2qmw by Molmil](/molmil-images/mine/2qmw) | The crystal structure of the prephenate dehydratase (PDT) from Staphylococcus aureus subsp. aureus Mu50 | Descriptor: | 1,2-ETHANEDIOL, ACETATE ION, DI(HYDROXYETHYL)ETHER, ... | Authors: | Tan, K, Zhang, R, Li, H, Gu, M, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2007-07-17 | Release date: | 2007-08-07 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structures of open (R) and close (T) states of prephenate dehydratase (PDT) - implication of allosteric regulation by L-phenylalanine. J.Struct.Biol., 162, 2008
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8D6Y
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![BU of 8d6y by Molmil](/molmil-images/mine/8d6y) | |
8D6X
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![BU of 8d6x by Molmil](/molmil-images/mine/8d6x) | |
8D6W
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![BU of 8d6w by Molmil](/molmil-images/mine/8d6w) | |
8D6V
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![BU of 8d6v by Molmil](/molmil-images/mine/8d6v) | |
2QHK
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![BU of 2qhk by Molmil](/molmil-images/mine/2qhk) | |
2QMX
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![BU of 2qmx by Molmil](/molmil-images/mine/2qmx) | The crystal structure of L-Phe inhibited prephenate dehydratase from Chlorobium tepidum TLS | Descriptor: | 1,2-ETHANEDIOL, ACETATE ION, PHENYLALANINE, ... | Authors: | Tan, K, Li, H, Clancy, S, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2007-07-17 | Release date: | 2007-08-07 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structures of open (R) and close (T) states of prephenate dehydratase (PDT) - implication of allosteric regulation by L-phenylalanine. J.Struct.Biol., 162, 2008
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6WB9
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![BU of 6wb9 by Molmil](/molmil-images/mine/6wb9) | Structure of the S. cerevisiae ER membrane complex | Descriptor: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 2-acetamido-2-deoxy-beta-D-glucopyranose, ER membrane protein complex subunit 1, ... | Authors: | Bai, L, Li, H. | Deposit date: | 2020-03-26 | Release date: | 2020-06-03 | Last modified: | 2020-09-02 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Structure of the ER membrane complex, a transmembrane-domain insertase. Nature, 584, 2020
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8D4X
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![BU of 8d4x by Molmil](/molmil-images/mine/8d4x) | Structure of the human UBR5 HECT-type E3 ubiquitin ligase in a dimeric form | Descriptor: | E3 ubiquitin-protein ligase UBR5, ZINC ION | Authors: | Wang, F, He, Q, Lin, G, Li, H. | Deposit date: | 2022-06-02 | Release date: | 2023-04-19 | Last modified: | 2024-06-12 | Method: | ELECTRON MICROSCOPY (2.8 Å) | Cite: | Structure of the human UBR5 E3 ubiquitin ligase. Structure, 31, 2023
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6WGI
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![BU of 6wgi by Molmil](/molmil-images/mine/6wgi) | Atomic model of the mutant OCCM (ORC-Cdc6-Cdt1-Mcm2-7 with Mcm6 WHD truncation) loaded on DNA at 10.5 A resolution | Descriptor: | Cell division control protein 6, Cell division cycle protein CDT1, DNA (34-MER), ... | Authors: | Yuan, Z, Schneider, S, Dodd, T, Riera, A, Bai, L, Yan, C, Magdalou, I, Ivanov, I, Stillman, B, Li, H, Speck, C. | Deposit date: | 2020-04-05 | Release date: | 2020-07-15 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (10 Å) | Cite: | Structural mechanism of helicase loading onto replication origin DNA by ORC-Cdc6. Proc.Natl.Acad.Sci.USA, 117, 2020
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2R7A
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![BU of 2r7a by Molmil](/molmil-images/mine/2r7a) | |
2RE1
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![BU of 2re1 by Molmil](/molmil-images/mine/2re1) | Crystal structure of aspartokinase alpha and beta subunits | Descriptor: | Aspartokinase, alpha and beta subunits, CALCIUM ION | Authors: | Chang, C, Li, H, Gu, M, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2007-09-25 | Release date: | 2007-10-09 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.75 Å) | Cite: | Crystal structure of aspartokinase alpha and beta subunits. To be Published
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6WGG
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![BU of 6wgg by Molmil](/molmil-images/mine/6wgg) | Atomic model of pre-insertion mutant OCCM-DNA complex(ORC-Cdc6-Cdt1-Mcm2-7 with Mcm6 WHD truncation) | Descriptor: | Cell division control protein 6, Cell division cycle protein CDT1, DNA (41-MER), ... | Authors: | Yuan, Z, Schneider, S, Dodd, T, Riera, A, Bai, L, Yan, C, Magdalou, I, Ivanov, I, Stillman, B, Li, H, Speck, C. | Deposit date: | 2020-04-05 | Release date: | 2020-07-15 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (8.1 Å) | Cite: | Structural mechanism of helicase loading onto replication origin DNA by ORC-Cdc6. Proc.Natl.Acad.Sci.USA, 117, 2020
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6WGC
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![BU of 6wgc by Molmil](/molmil-images/mine/6wgc) | Atomic model of semi-attached mutant OCCM-DNA complex (ORC-Cdc6-Cdt1-Mcm2-7 with Mcm6 WHD truncation) | Descriptor: | Cell division control protein 6, DNA (41-MER), DNA replication licensing factor MCM3, ... | Authors: | Yuan, Z, Schneider, S, Dodd, T, Riera, A, Bai, L, Yan, C, Magdalou, I, Ivanov, I, Stillman, B, Li, H, Speck, C. | Deposit date: | 2020-04-05 | Release date: | 2020-07-15 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (4.3 Å) | Cite: | Structural mechanism of helicase loading onto replication origin DNA by ORC-Cdc6. Proc.Natl.Acad.Sci.USA, 117, 2020
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8D2Q
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![BU of 8d2q by Molmil](/molmil-images/mine/8d2q) | Structure of Acidothermus cellulolyticus Cas9 ternary complex (Post-cleavage 1) | Descriptor: | CRISPR-associated endonuclease, Csn1 family, DNA non-target strand (5'-D(P*AP*TP*AP*CP*AP*CP*CP*AP*AP*GP*CP*T)-3'), ... | Authors: | Rai, J, Das, A, Li, H. | Deposit date: | 2022-05-30 | Release date: | 2023-12-20 | Last modified: | 2024-05-01 | Method: | ELECTRON MICROSCOPY (2.58 Å) | Cite: | Coupled catalytic states and the role of metal coordination in Cas9. Nat Catal, 6, 2023
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8D2K
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![BU of 8d2k by Molmil](/molmil-images/mine/8d2k) | Structure of Acidothermus cellulolyticus Cas9 ternary complex (Cleavage Intermediate 2) | Descriptor: | CRISPR-associated endonuclease, Csn1 family, DNA non-target strand (5'-D(P*AP*GP*A)-3'), ... | Authors: | Rai, J, Das, A, Li, H. | Deposit date: | 2022-05-30 | Release date: | 2023-12-20 | Last modified: | 2024-05-01 | Method: | ELECTRON MICROSCOPY (2.43 Å) | Cite: | Coupled catalytic states and the role of metal coordination in Cas9. Nat Catal, 6, 2023
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8D2O
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![BU of 8d2o by Molmil](/molmil-images/mine/8d2o) | Structure of Acidothermus cellulolyticus Cas9 ternary complex (Post-cleavage 2) | Descriptor: | CRISPR-associated endonuclease, Csn1 family, DNA non-target strand (5'-D(P*AP*TP*AP*CP*AP*CP*CP*AP*AP*GP*CP*T)-3'), ... | Authors: | Rai, J, Das, A, Li, H. | Deposit date: | 2022-05-30 | Release date: | 2023-12-20 | Last modified: | 2024-05-01 | Method: | ELECTRON MICROSCOPY (2.66 Å) | Cite: | Coupled catalytic states and the role of metal coordination in Cas9. Nat Catal, 6, 2023
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8D2N
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![BU of 8d2n by Molmil](/molmil-images/mine/8d2n) | Structure of Acidothermus cellulolyticus Cas9 ternary complex (Pre-cleavage) | Descriptor: | CRISPR-associated endonuclease, Csn1 family, DNA non-target strand (5'-D(P*TP*AP*CP*AP*CP*CP*AP*AP*GP*CP*T)-3'), ... | Authors: | Rai, J, Das, A, Li, H. | Deposit date: | 2022-05-30 | Release date: | 2023-12-20 | Last modified: | 2024-05-01 | Method: | ELECTRON MICROSCOPY (2.88 Å) | Cite: | Coupled catalytic states and the role of metal coordination in Cas9. Nat Catal, 6, 2023
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8D2P
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![BU of 8d2p by Molmil](/molmil-images/mine/8d2p) | Structure of Acidothermus cellulolyticus Cas9 ternary complex (Target bound) | Descriptor: | CRISPR-associated endonuclease, Csn1 family, DNA target strand (5'-D(P*CP*CP*AP*GP*GP*AP*TP*CP*TP*TP*GP*CP*CP*AP*TP*CP*CP*TP*AP*CP*CP*TP*CP*T)-3'), ... | Authors: | Rai, J, Das, A, Li, H. | Deposit date: | 2022-05-30 | Release date: | 2023-12-20 | Last modified: | 2024-05-01 | Method: | ELECTRON MICROSCOPY (2.78 Å) | Cite: | Coupled catalytic states and the role of metal coordination in Cas9. Nat Catal, 6, 2023
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8D2L
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![BU of 8d2l by Molmil](/molmil-images/mine/8d2l) | Structure of Acidothermus cellulolyticus Cas9 ternary complex (Cleavage Intermediate 1) | Descriptor: | CRISPR-associated endonuclease, Csn1 family, DNA non-target strand (5'-D(P*AP*GP*A)-3'), ... | Authors: | Rai, J, Das, A, Li, H. | Deposit date: | 2022-05-30 | Release date: | 2023-12-20 | Last modified: | 2024-05-01 | Method: | ELECTRON MICROSCOPY (2.21 Å) | Cite: | Coupled catalytic states and the role of metal coordination in Cas9. Nat Catal, 6, 2023
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6WJV
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![BU of 6wjv by Molmil](/molmil-images/mine/6wjv) | Structure of the Saccharomyces cerevisiae polymerase epsilon holoenzyme | Descriptor: | DNA polymerase epsilon catalytic subunit A, DNA polymerase epsilon subunit B, DNA polymerase epsilon subunit C, ... | Authors: | Yuan, Z, Georgescu, R, Schauer, G.D, O'Donnell, M, Li, H. | Deposit date: | 2020-04-14 | Release date: | 2020-07-08 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Structure of the polymerase epsilon holoenzyme and atomic model of the leading strand replisome. Nat Commun, 11, 2020
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2RG7
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![BU of 2rg7 by Molmil](/molmil-images/mine/2rg7) | |
1R5I
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![BU of 1r5i by Molmil](/molmil-images/mine/1r5i) | Crystal structure of the MAM-MHC complex | Descriptor: | HLA class II histocompatibility antigen, DR alpha chain, DRB1-1 beta chain, ... | Authors: | Zhao, Y, Li, Z, Drozd, S.J, Guo, Y, Mourad, W, Li, H. | Deposit date: | 2003-10-10 | Release date: | 2004-03-16 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Crystal structure of Mycoplasma arthritidis mitogen complexed with HLA-DR1 reveals a novel superantigen fold and a dimerized superantigen-MHC complex. Structure, 12, 2004
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