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6ZTJ
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BU of 6ztj by Molmil
E. coli 70S-RNAP expressome complex in NusG-coupled state (38 nt intervening mRNA)
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S1, ...
Authors:Webster, M.W, Takacs, M, Weixlbaumer, A.
Deposit date:2020-07-20
Release date:2020-09-16
Last modified:2024-04-24
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structural basis of transcription-translation coupling and collision in bacteria.
Science, 369, 2020
6ZTN
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BU of 6ztn by Molmil
E. coli 70S-RNAP expressome complex in NusG-coupled state (42 nt intervening mRNA)
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Webster, M.W, Takacs, M, Weixlbaumer, A.
Deposit date:2020-07-20
Release date:2020-09-16
Last modified:2024-04-24
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Structural basis of transcription-translation coupling and collision in bacteria.
Science, 369, 2020
6ZU1
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BU of 6zu1 by Molmil
E. coli 70S-RNAP expressome complex in uncoupled state 2
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Webster, M.W, Takacs, M, Weixlbaumer, A.
Deposit date:2020-07-21
Release date:2020-09-16
Last modified:2024-04-24
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Structural basis of transcription-translation coupling and collision in bacteria.
Science, 369, 2020
6ZTL
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BU of 6ztl by Molmil
E. coli 70S-RNAP expressome complex in collided state bound to NusG
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Webster, M.W, Takacs, M, Weixlbaumer, A.
Deposit date:2020-07-20
Release date:2020-09-16
Last modified:2024-04-24
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Structural basis of transcription-translation coupling and collision in bacteria.
Science, 369, 2020
6ZTO
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BU of 6zto by Molmil
E. coli 70S-RNAP expressome complex in uncoupled state 1
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Webster, M.W, Takacs, M, Weixlbaumer, A.
Deposit date:2020-07-20
Release date:2020-09-23
Last modified:2024-04-24
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Structural basis of transcription-translation coupling and collision in bacteria.
Science, 369, 2020
7C1E
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BU of 7c1e by Molmil
Crystal structure of Kluyveromyces polyspora ADH (KpADH) mutant (Y127W)
Descriptor: Epimerase domain-containing protein, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Wu, Y.F, Zhou, J.Y, Liu, Y.F, Xu, G.C, Ni, Y.
Deposit date:2020-05-03
Release date:2021-05-05
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Engineering an Alcohol Dehydrogenase from Kluyveromyces polyspora for Efficient Synthesis of Ibrutinib Intermediate
Adv.Synth.Catal., 2021
7SH6
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BU of 7sh6 by Molmil
Crystal structure of a PET hydrolase mutant from Ideonella Sakaiensis
Descriptor: Poly(ethylene terephthalate) hydrolase, SULFATE ION
Authors:Kim, W, Zhang, Y.
Deposit date:2021-10-08
Release date:2022-04-06
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (1.44 Å)
Cite:Machine learning-aided engineering of hydrolases for PET depolymerization.
Nature, 604, 2022
8JG8
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BU of 8jg8 by Molmil
The crystal structure of human aurka kinase domain in the complex with aurka-compound 25
Descriptor: 4-[5-[3-[bis(oxidanylidene)-$l^5-sulfanyl]oxyphenyl]-7H-pyrrolo[2,3-d]pyrimidin-4-yl]morpholine, Aurora kinase A
Authors:Zhu, C.J, Zhang, Z.M.
Deposit date:2023-05-19
Release date:2024-04-17
Method:X-RAY DIFFRACTION (2.90002346 Å)
Cite:Global Reactivity Profiling of the Catalytic Lysine in Human Kinome for Covalent Inhibitor Development.
Angew.Chem.Int.Ed.Engl., 63, 2024
8JMX
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BU of 8jmx by Molmil
The crystal structure of human aurka kinase domain in complex with AURKA-A2
Descriptor: 5-(4-morpholin-4-yl-7H-pyrrolo[2,3-d]pyrimidin-5-yl)-2-oxidanyl-benzaldehyde, Aurora kinase A
Authors:Zhu, C.J, Zhang, Z.M.
Deposit date:2023-06-05
Release date:2023-10-18
Method:X-RAY DIFFRACTION (2.95020175 Å)
Cite:Multitarget inhibitors/probes that target LRRK2 and AURORA A kinases noncovalently and covalently.
Chem.Commun.(Camb.), 59, 2023
6LWA
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BU of 6lwa by Molmil
Crystal structure of human NEIL1(P2G, E3Q, K242) bound to duplex DNA containing 5-hydroxyuracil (5-OHU)
Descriptor: DNA (5'-D(*CP*GP*TP*CP*CP*AP*(OHU)P*GP*TP*CP*TP*AP*C)-3'), DNA (5'-D(*TP*AP*GP*AP*CP*CP*TP*GP*GP*AP*CP*GP*G)-3'), Endonuclease 8-like 1
Authors:Liu, M.H, Zhang, J, Zhu, C.X, Zhang, X.X, Gao, Y.Q, Yi, C.Q.
Deposit date:2020-02-07
Release date:2021-06-09
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.76 Å)
Cite:DNA repair glycosylase hNEIL1 triages damaged bases via competing interaction modes.
Nat Commun, 12, 2021
6LWF
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BU of 6lwf by Molmil
Crystal structure of human NEIL1(P2G, E3Q, K242) bound to duplex DNA containing guanidinohydantoin (Gh)
Descriptor: DNA (5'-D(*CP*GP*TP*CP*CP*AP*(DGH)P*GP*TP*CP*TP*AP*C)-3'), DNA (5'-D(*TP*AP*GP*AP*CP*CP*TP*GP*GP*AP*CP*GP*G)-3'), Endonuclease 8-like 1
Authors:Liu, M.H, Zhang, J, Zhu, C.X, Zhang, X.X, Gao, Y.Q, Yi, C.Q.
Deposit date:2020-02-07
Release date:2021-06-09
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.79 Å)
Cite:DNA repair glycosylase hNEIL1 triages damaged bases via competing interaction modes.
Nat Commun, 12, 2021
6LWC
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BU of 6lwc by Molmil
Crystal structure of human NEIL1(P2G, E3Q, K242) bound to duplex DNA containing spiroiminodihydantoin (Sp)
Descriptor: DNA (5'-D(*CP*GP*TP*CP*CP*AP*(DSP)P*GP*TP*CP*TP*AP*C)-3'), DNA (5'-D(*TP*AP*GP*AP*CP*CP*TP*GP*GP*AP*CP*GP*G)-3'), Endonuclease 8-like 1
Authors:Liu, M.H, Zhang, J, Zhu, C.X, Zhang, X.X, Gao, Y.Q, Yi, C.Q.
Deposit date:2020-02-07
Release date:2021-06-09
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.91 Å)
Cite:DNA repair glycosylase hNEIL1 triages damaged bases via competing interaction modes.
Nat Commun, 12, 2021
6LWG
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BU of 6lwg by Molmil
Crystal structure of human NEIL1(P2G, E3Q, R242) bound to duplex DNA containing guanidinohydantoin (Gh)
Descriptor: DNA (5'-D(*CP*GP*TP*CP*CP*AP*(DGH)P*GP*TP*CP*TP*AP*C)-3'), DNA (5'-D(*TP*AP*GP*AP*CP*CP*TP*GP*GP*AP*CP*GP*G)-3'), Endonuclease 8-like 1, ...
Authors:Liu, M.H, Zhang, J, Zhu, C.X, Zhang, X.X, Gao, Y.Q, Yi, C.Q.
Deposit date:2020-02-07
Release date:2021-06-09
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.53 Å)
Cite:DNA repair glycosylase hNEIL1 triages damaged bases via competing interaction modes.
Nat Commun, 12, 2021
6LWB
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BU of 6lwb by Molmil
Crystal structure of human NEIL1(P2G, E3Q, R242) bound to duplex DNA containing 5-hydroxyuracil (5-OHU)
Descriptor: DNA (5'-D(*CP*GP*TP*CP*CP*AP*(OHU)P*GP*TP*CP*TP*AP*C)-3'), DNA (5'-D(*TP*AP*GP*AP*CP*CP*TP*GP*GP*AP*CP*GP*G)-3'), Endonuclease 8-like 1
Authors:Liu, M.H, Zhang, J, Zhu, C.X, Zhang, X.X, Gao, Y.Q, Yi, C.Q.
Deposit date:2020-02-07
Release date:2021-06-09
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:DNA repair glycosylase hNEIL1 triages damaged bases via competing interaction modes.
Nat Commun, 12, 2021
6LWN
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BU of 6lwn by Molmil
Crystal structure of human NEIL1(R242, G249P) bound to duplex DNA containing 2'-fluoro-2'-deoxy-5,6-dihydrouridine
Descriptor: DNA (5'-D(*CP*GP*TP*CP*CP*AP*(FDU)P*GP*TP*CP*TP*AP*C)-3'), DNA (5'-D(*TP*AP*GP*AP*CP*CP*TP*GP*GP*AP*CP*GP*G)-3'), Endonuclease 8-like 1, ...
Authors:Liu, M.H, Zhang, J, Zhu, C.X, Zhang, X.X, Gao, Y.Q, Yi, C.Q.
Deposit date:2020-02-07
Release date:2021-06-09
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.74 Å)
Cite:DNA repair glycosylase hNEIL1 triages damaged bases via competing interaction modes.
Nat Commun, 12, 2021
6LWO
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BU of 6lwo by Molmil
Crystal structure of human NEIL1(R242, Y244H) bound to duplex DNA containing 2'-fluoro-2'-deoxy-5,6-dihydrouridine
Descriptor: DNA (5'-D(*CP*GP*TP*CP*CP*AP*(FDU)P*GP*TP*CP*TP*AP*C)-3'), DNA (5'-D(*TP*AP*GP*AP*CP*CP*TP*GP*GP*AP*CP*GP*G)-3'), Endonuclease 8-like 1, ...
Authors:Liu, M.H, Zhang, J, Zhu, C.X, Zhang, X.X, Gao, Y.Q, Yi, C.Q.
Deposit date:2020-02-07
Release date:2021-06-09
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.51 Å)
Cite:DNA repair glycosylase hNEIL1 triages damaged bases via competing interaction modes.
Nat Commun, 12, 2021
6LWM
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BU of 6lwm by Molmil
Crystal structure of human NEIL1(K242) bound to duplex DNA containing 2'-fluoro-2'-deoxy-5,6-dihydrouridine
Descriptor: DNA (5'-D(*CP*GP*TP*CP*CP*AP*(FDU)P*GP*TP*CP*TP*AP*C)-3'), DNA (5'-D(*TP*AP*GP*AP*CP*CP*TP*GP*GP*AP*CP*GP*G)-3'), Endonuclease 8-like 1, ...
Authors:Liu, M.H, Zhang, J, Zhu, C.X, Zhang, X.X, Gao, Y.Q, Yi, C.Q.
Deposit date:2020-02-07
Release date:2021-06-09
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.67 Å)
Cite:DNA repair glycosylase hNEIL1 triages damaged bases via competing interaction modes.
Nat Commun, 12, 2021
6LWI
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BU of 6lwi by Molmil
Crystal structure of human NEIL1(P2G, E3Q, R242) bound to duplex DNA containing dihydrothymine (DHT)
Descriptor: DNA (5'-D(*CP*GP*TP*CP*CP*AP*(TDH)P*GP*TP*CP*TP*AP*C)-3'), DNA (5'-D(*TP*AP*GP*AP*CP*CP*TP*GP*GP*AP*CP*GP*G)-3'), Endonuclease 8-like 1
Authors:Liu, M.H, Zhang, J, Zhu, C.X, Zhang, X.X, Gao, Y.Q, Yi, C.Q.
Deposit date:2020-02-07
Release date:2021-06-09
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.72 Å)
Cite:DNA repair glycosylase hNEIL1 triages damaged bases via competing interaction modes.
Nat Commun, 12, 2021
6LWJ
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BU of 6lwj by Molmil
Crystal structure of human NEIL1(P2G, E3Q, K242) bound to duplex DNA containing dihydrouracil (DHU)
Descriptor: DNA (5'-D(*CP*GP*TP*CP*CP*AP*(UDH)P*GP*TP*CP*TP*AP*C)-3'), DNA (5'-D(*TP*AP*GP*AP*CP*CP*TP*GP*GP*AP*CP*GP*G)-3'), Endonuclease 8-like 1, ...
Authors:Liu, M.H, Zhang, J, Zhu, C.X, Zhang, X.X, Gao, Y.Q, Yi, C.Q.
Deposit date:2020-02-07
Release date:2021-06-09
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.83 Å)
Cite:DNA repair glycosylase hNEIL1 triages damaged bases via competing interaction modes.
Nat Commun, 12, 2021
6LWK
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BU of 6lwk by Molmil
Crystal structure of human NEIL1(P2G, E3Q, R242) bound to duplex DNA containing dihydrouracil (DHU)
Descriptor: DNA (5'-D(*CP*GP*TP*CP*CP*AP*(UDH)P*GP*TP*CP*TP*AP*C)-3'), DNA (5'-D(*TP*AP*GP*AP*CP*CP*TP*GP*GP*AP*CP*GP*G)-3'), Endonuclease 8-like 1, ...
Authors:Liu, M.H, Zhang, J, Zhu, C.X, Zhang, X.X, Gao, Y.Q, Yi, C.Q.
Deposit date:2020-02-07
Release date:2021-06-09
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.88 Å)
Cite:DNA repair glycosylase hNEIL1 triages damaged bases via competing interaction modes.
Nat Commun, 12, 2021
6LWD
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BU of 6lwd by Molmil
Crystal structure of human NEIL1(P2G, E3Q, R242) bound to duplex DNA containing spiroiminodihydantoin (Sp)
Descriptor: DNA (5'-D(*CP*GP*TP*CP*CP*AP*(DSP)P*GP*TP*CP*TP*AP*C)-3'), DNA (5'-D(*TP*AP*GP*AP*CP*CP*TP*GP*GP*AP*CP*GP*G)-3'), Endonuclease 8-like 1, ...
Authors:Liu, M.H, Zhang, J, Zhu, C.X, Zhang, X.X, Gao, Y.Q, Yi, C.Q.
Deposit date:2020-02-07
Release date:2021-06-09
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.41 Å)
Cite:DNA repair glycosylase hNEIL1 triages damaged bases via competing interaction modes.
Nat Commun, 12, 2021
6LWP
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BU of 6lwp by Molmil
Crystal structure of human NEIL1(R242, Y244R) bound to duplex DNA containing 2'-fluoro-2'-deoxy-5,6-dihydrouridine
Descriptor: DNA (5'-D(*CP*GP*TP*CP*CP*AP*(FDU)P*GP*TP*CP*TP*AP*C)-3'), DNA (5'-D(*TP*AP*GP*AP*CP*CP*TP*GP*GP*AP*CP*GP*G)-3'), Endonuclease 8-like 1, ...
Authors:Liu, M.H, Zhang, J, Zhu, C.X, Zhang, X.X, Gao, Y.Q, Yi, C.Q.
Deposit date:2020-02-07
Release date:2021-06-09
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.64 Å)
Cite:DNA repair glycosylase hNEIL1 triages damaged bases via competing interaction modes.
Nat Commun, 12, 2021
6LWH
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BU of 6lwh by Molmil
Crystal structure of human NEIL1(P2G, E3Q, K242) bound to duplex DNA containing dihydrothymine (DHT)
Descriptor: DNA (5'-D(*CP*GP*TP*CP*CP*AP*(TDH)P*GP*TP*CP*TP*AP*C)-3'), DNA (5'-D(*TP*AP*GP*AP*CP*CP*TP*GP*GP*AP*CP*GP*G)-3'), Endonuclease 8-like 1, ...
Authors:Liu, M.H, Zhang, J, Zhu, C.X, Zhang, X.X, Gao, Y.Q, Yi, C.Q.
Deposit date:2020-02-07
Release date:2021-06-09
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.78 Å)
Cite:DNA repair glycosylase hNEIL1 triages damaged bases via competing interaction modes.
Nat Commun, 12, 2021
6LWL
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BU of 6lwl by Molmil
Crystal structure of human NEIL1(R242) bound to duplex DNA containing 2'-fluoro-2'-deoxy-5,6-dihydrouridine
Descriptor: DNA (5'-D(*CP*GP*TP*CP*CP*AP*(FDU)P*GP*TP*CP*TP*AP*C)-3'), DNA (5'-D(*TP*AP*GP*AP*CP*CP*TP*GP*GP*AP*CP*GP*G)-3'), Endonuclease 8-like 1, ...
Authors:Liu, M.H, Zhang, J, Zhu, C.X, Zhang, X.X, Gao, Y.Q, Yi, C.Q.
Deposit date:2020-02-07
Release date:2021-06-09
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:DNA repair glycosylase hNEIL1 triages damaged bases via competing interaction modes.
Nat Commun, 12, 2021
6LWQ
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BU of 6lwq by Molmil
Crystal structure of human NEIL1(R242) bound to duplex DNA containing a C:T mismatch
Descriptor: DNA (5'-D(*CP*GP*TP*CP*CP*AP*TP*GP*TP*CP*TP*AP*C)-3'), DNA (5'-D(*TP*AP*GP*AP*CP*CP*TP*GP*GP*AP*CP*GP*G)-3'), Endonuclease 8-like 1
Authors:Liu, M.H, Zhang, J, Zhu, C.X, Zhang, X.X, Gao, Y.Q, Yi, C.Q.
Deposit date:2020-02-07
Release date:2021-06-09
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.89 Å)
Cite:DNA repair glycosylase hNEIL1 triages damaged bases via competing interaction modes.
Nat Commun, 12, 2021

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PDB entries from 2024-11-06

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