7C1E
Crystal structure of Kluyveromyces polyspora ADH (KpADH) mutant (Y127W)
Summary for 7C1E
| Entry DOI | 10.2210/pdb7c1e/pdb |
| Descriptor | Epimerase domain-containing protein, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE (3 entities in total) |
| Functional Keywords | alcohol dehydrogenase(kpadh-y127w), nadph, oxidoreductase |
| Biological source | Vanderwaltozyma polyspora (strain ATCC 22028 / DSM 70294) |
| Total number of polymer chains | 2 |
| Total formula weight | 79431.17 |
| Authors | Wu, Y.F.,Zhou, J.Y.,Liu, Y.F.,Xu, G.C.,Ni, Y. (deposition date: 2020-05-03, release date: 2021-05-05, Last modification date: 2023-11-29) |
| Primary citation | Wu, Y.F.,Zhou, J.Y.,Ni, J.,Zhu, C.,Sun, Z.,Xu, G.C.,Ni, Y. Engineering an Alcohol Dehydrogenase from Kluyveromyces polyspora for Efficient Synthesis of Ibrutinib Intermediate Adv.Synth.Catal., 2021 Cited by DOI: 10.1002/ADSC.202001313PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.75 Å) |
Structure validation
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