8SCP
 
 | | Bst DNA polymerase I Large Fragment wildtype D598A with 3'-amino primer, dGTP, and calcium time-resolved 1h | | Descriptor: | 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, CALCIUM ION, DIPHOSPHATE, ... | | Authors: | Fang, Z, Lelyveld, V.S, Szostak, J.W. | | Deposit date: | 2023-04-05 | | Release date: | 2023-10-25 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.08 Å) | | Cite: | Trivalent rare earth metal cofactors confer rapid NP-DNA polymerase activity.
Science, 382, 2023
|
|
8SCR
 | | Bst DNA polymerase I Large Fragment wildtype D598A with 3'-amino primer, dGTP, and calcium time-resolved 4h | | Descriptor: | 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, CALCIUM ION, DIPHOSPHATE, ... | | Authors: | Fang, Z, Lelyveld, V.S, Szostak, J.W. | | Deposit date: | 2023-04-05 | | Release date: | 2023-10-25 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Trivalent rare earth metal cofactors confer rapid NP-DNA polymerase activity.
Science, 382, 2023
|
|
8SCQ
 | | Bst DNA polymerase I Large Fragment wildtype D598A with 3'-amino primer, dGTP, and calcium time-resolved 2h | | Descriptor: | 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, CALCIUM ION, DIPHOSPHATE, ... | | Authors: | Fang, Z, Lelyveld, V.S, Szostak, J.W. | | Deposit date: | 2023-04-05 | | Release date: | 2023-10-25 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.18 Å) | | Cite: | Trivalent rare earth metal cofactors confer rapid NP-DNA polymerase activity.
Science, 382, 2023
|
|
8SCN
 | | Bst DNA polymerase I Large Fragment mutant F710Y/D598A with 3'-amino primer, dGTP, and calcium time-resolved 24h (Product State) | | Descriptor: | CALCIUM ION, DIPHOSPHATE, DNA polymerase I, ... | | Authors: | Fang, Z, Lelyveld, V.S, Szostak, J.W. | | Deposit date: | 2023-04-05 | | Release date: | 2023-10-25 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Trivalent rare earth metal cofactors confer rapid NP-DNA polymerase activity.
Science, 382, 2023
|
|
8SCS
 | | Bst DNA polymerase I Large Fragment wildtype D598A with 3'-amino primer, dGTP, and calcium time-resolved 8h | | Descriptor: | 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, CALCIUM ION, DIPHOSPHATE, ... | | Authors: | Fang, Z, Lelyveld, V.S, Szostak, J.W. | | Deposit date: | 2023-04-05 | | Release date: | 2023-10-25 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Trivalent rare earth metal cofactors confer rapid NP-DNA polymerase activity.
Science, 382, 2023
|
|
8SCT
 | | Bst DNA polymerase I Large Fragment wildtype D598A with 3'-amino primer, dGTP, and calcium time-resolved 24h | | Descriptor: | 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, CALCIUM ION, DIPHOSPHATE, ... | | Authors: | Fang, Z, Lelyveld, V.S, Szostak, J.W. | | Deposit date: | 2023-04-05 | | Release date: | 2023-10-25 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.34 Å) | | Cite: | Trivalent rare earth metal cofactors confer rapid NP-DNA polymerase activity.
Science, 382, 2023
|
|
8SCU
 | | Bst DNA polymerase I Large Fragment wildtype D598A with 3'-amino primer, dGTP, and calcium time-resolved 48h (Product State) | | Descriptor: | 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, CALCIUM ION, DIPHOSPHATE, ... | | Authors: | Fang, Z, Lelyveld, V.S, Szostak, J.W. | | Deposit date: | 2023-04-05 | | Release date: | 2023-10-25 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.38 Å) | | Cite: | Trivalent rare earth metal cofactors confer rapid NP-DNA polymerase activity.
Science, 382, 2023
|
|
5UEG
 | | RNA primer-template complex with guanosine dinucleotide G(5')pppp(5')G ligand | | Descriptor: | RNA (5'-R(*(LCC)P*(LCC)P*(LCC)P*GP*AP*CP*UP*UP*AP*AP*GP*UP*CP*G)-3'), [[(2~{R},3~{S},4~{R},5~{R})-5-(2-azanyl-6-oxidanylidene-1~{H}-purin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl] [[[(2~{R},3~{S},4~{R},5~{R})-5-(2-azanyl-6-oxidanylidene-1~{H}-purin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl]oxy-oxidanyl-phosphoryl] hydrogen phosphate | | Authors: | Zhang, W, Tam, C.P, Szostak, J.W. | | Deposit date: | 2017-01-02 | | Release date: | 2017-07-05 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Insight into the mechanism of nonenzymatic RNA primer extension from the structure of an RNA-GpppG complex.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
|
|
5UEE
 | |
5UEF
 | |
5UED
 | | RNA primer-template complex with guanosine dinucleotide ligand G(5')pp(5')G | | Descriptor: | RNA (5'-R(*(LCC)P*(LCC)P*(LCC)P*GP*AP*CP*UP*UP*AP*AP*GP*UP*CP*G)-3'), [[(2~{R},3~{S},4~{R},5~{R})-5-(2-azanyl-6-oxidanylidene-1~{H}-purin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl] [(2~{R},3~{S},4~{R},5~{R})-5-(2-azanyl-6-oxidanylidene-1~{H}-purin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methyl hydrogen phosphate | | Authors: | Zhang, W, Tam, C.P, Szostak, J.W. | | Deposit date: | 2017-01-01 | | Release date: | 2017-07-05 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | Insight into the mechanism of nonenzymatic RNA primer extension from the structure of an RNA-GpppG complex.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
|
|
5V0J
 | | RNA duplex with 2-MeImpG analogue bound-2 binding sites | | Descriptor: | 5'-O-[(S)-hydroxy(4-methyl-1H-imidazol-5-yl)phosphoryl]guanosine, MAGNESIUM ION, RNA (5'-R(*(LCC)P*(LCC)P*(LCA)P*(LCG)P*AP*CP*UP*UP*AP*AP*GP*UP*CP*U)-3') | | Authors: | Zhang, W, Tam, C.P, Szostak, J.W. | | Deposit date: | 2017-02-28 | | Release date: | 2017-03-08 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | Structural Rationale for the Enhanced Catalysis of Nonenzymatic RNA Primer Extension by a Downstream Oligonucleotide.
J. Am. Chem. Soc., 140, 2018
|
|
5V0O
 | | RNA hairpin structure containing 2-MeImpG analogue bound | | Descriptor: | 5'-O-[(S)-hydroxy(4-methyl-1H-imidazol-5-yl)phosphoryl]guanosine, RNA (25-MER), RNA (5'-R(*GP*CP*AP*CP*CP*UP*CP*A)-3') | | Authors: | Zhang, W, Tam, C.P, Szostak, J.W. | | Deposit date: | 2017-02-28 | | Release date: | 2018-02-21 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Structural Rationale for the Enhanced Catalysis of Nonenzymatic RNA Primer Extension by a Downstream Oligonucleotide.
J. Am. Chem. Soc., 140, 2018
|
|
5V0H
 | | RNA duplex with 2-MeImpG analogue bound-one binding site | | Descriptor: | 5'-O-[(S)-hydroxy(4-methyl-1H-imidazol-5-yl)phosphoryl]guanosine, MAGNESIUM ION, RNA (5'-R(*(LCC)P*(LCC)P*(LCC)P*(LCG)P*AP*CP*UP*UP*AP*AP*GP*UP*CP*GP*G)-3') | | Authors: | Zhang, W, Tam, C.P, Szostak, J.W. | | Deposit date: | 2017-02-28 | | Release date: | 2017-03-08 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Structural Rationale for the Enhanced Catalysis of Nonenzymatic RNA Primer Extension by a Downstream Oligonucleotide.
J. Am. Chem. Soc., 140, 2018
|
|
5VGW
 | | RNA hairpin structure containing tetraloop/receptor motif | | Descriptor: | RNA (5'-R(*CP*UP*GP*CP*UP*GP*GP*CP*UP*AP*AP*GP*GP*CP*CP*CP*GP*AP*AP*AP*GP*G)-3'), RNA (5'-R(P*GP*CP*UP*AP*UP*GP*CP*CP*UP*GP*CP*UP*G)-3') | | Authors: | Zhang, W, Szostak, J.W. | | Deposit date: | 2017-04-11 | | Release date: | 2018-02-21 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (2.42 Å) | | Cite: | Structural Rationale for the Enhanced Catalysis of Nonenzymatic RNA Primer Extension by a Downstream Oligonucleotide.
J. Am. Chem. Soc., 140, 2018
|
|
5UX3
 | |
5UZ6
 | | RNA hairpin structure containing 2-MeImp-oligo analogue | | Descriptor: | RNA (25-MER), RNA (5'-D(*(8OS))-R(P*CP*AP*CP*CP*UP*CP*A)-3') | | Authors: | Zhang, W, Oh, S.S, Szostak, J.W. | | Deposit date: | 2017-02-24 | | Release date: | 2018-02-21 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Structural Rationale for the Enhanced Catalysis of Nonenzymatic RNA Primer Extension by a Downstream Oligonucleotide.
J. Am. Chem. Soc., 140, 2018
|
|
5V9Z
 | | RNA hairpin structure containing 2-MeImpG analogue bound | | Descriptor: | 5'-O-[(S)-hydroxy(4-methyl-1H-imidazol-5-yl)phosphoryl]guanosine, RNA (25-MER), RNA (5'-R(P*GP*CP*AP*CP*CP*UP*CP*A)-3') | | Authors: | Zhang, W, Szostak, J.W. | | Deposit date: | 2017-03-24 | | Release date: | 2018-02-21 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (2.51 Å) | | Cite: | Structural Rationale for the Enhanced Catalysis of Nonenzymatic RNA Primer Extension by a Downstream Oligonucleotide.
J. Am. Chem. Soc., 140, 2018
|
|
5VCF
 | | RNA hairpin structure containing tetraloop/receptor motif, complexed with 2-MeImpG analogue | | Descriptor: | 5'-O-[(S)-hydroxy(4-methyl-1H-imidazol-5-yl)phosphoryl]guanosine, RNA (5'-R(*CP*UP*AP*UP*GP*CP*CP*UP*GP*CP*UP*G)-3'), RNA (5'-R(*CP*UP*GP*CP*UP*GP*GP*CP*UP*AP*AP*GP*GP*CP*CP*CP*GP*AP*AP*AP*GP*G)-3') | | Authors: | Zhang, W, Szostak, J.W. | | Deposit date: | 2017-03-31 | | Release date: | 2018-02-21 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Structural Rationale for the Enhanced Catalysis of Nonenzymatic RNA Primer Extension by a Downstream Oligonucleotide.
J. Am. Chem. Soc., 140, 2018
|
|
5V0K
 | | RNA duplex with 2-MeImpG analogue bound-3 binding sites | | Descriptor: | 5'-O-[(S)-hydroxy(4-methyl-1H-imidazol-5-yl)phosphoryl]guanosine, MAGNESIUM ION, RNA (5'-R(*(LCC)P*(LCC)P*(LCC)P*(LCG)P*AP*CP*UP*UP*AP*AP*GP*UP*C)-3') | | Authors: | Zhang, W, Tam, C.P, Szostak, J.W. | | Deposit date: | 2017-02-28 | | Release date: | 2017-03-08 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | RNA duplex with 2-MeImpG analogue bound-3 binding sites
To Be Published
|
|
1AM0
 | | AMP RNA APTAMER COMPLEX, NMR, 8 STRUCTURES | | Descriptor: | ADENOSINE MONOPHOSPHATE, RNA APTAMER | | Authors: | Jiang, F, Kumar, R.A, Jones, R.A, Patel, D.J. | | Deposit date: | 1997-06-19 | | Release date: | 1997-07-23 | | Last modified: | 2024-05-22 | | Method: | SOLUTION NMR | | Cite: | Structural Basis of RNA Folding and Recognition in an AMP-RNA Aptamer Complex
Nature, 382, 1996
|
|
1UW1
 | |
1RAW
 | |
1RPV
 | | HIV-1 REV PROTEIN (RESIDUES 34-50) | | Descriptor: | HIV-1 REV PROTEIN | | Authors: | Scanlon, M.J, Fairlie, D.P, Craik, D.J, Englebretsen, D.R, West, M.L. | | Deposit date: | 1995-05-04 | | Release date: | 1995-10-15 | | Last modified: | 2022-03-02 | | Method: | SOLUTION NMR | | Cite: | NMR solution structure of the RNA-binding peptide from human immunodeficiency virus (type 1) Rev.
Biochemistry, 34, 1995
|
|
