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2AEI
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BU of 2aei by Molmil
Crystal structure of a ternary complex of factor VIIa/tissue factor and 2-[[6-[3-(aminoiminomethyl)phenoxy]-3,5-difluro-4-[(1-methyl-3-phenylpropyl)amino]-2-pyridinyl]oxy]-benzoic acid
Descriptor: 2-({6-{3-[AMINO(IMINO)METHYL]PHENOXY}-3,5-DIFLUORO-4-[(1-METHYL-3-PHENYLPROPYL)AMINO]-2-PYRIDINYL}OXY)BENZOIC ACID, CACODYLATE ION, CALCIUM ION, ...
Authors:Adler, M, Whitlow, M.
Deposit date:2005-07-22
Release date:2006-08-01
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.52 Å)
Cite:The discovery of fluoropyridine-based inhibitors of the Factor VIIa/TF complex.
Bioorg.Med.Chem.Lett., 15, 2005
2Q1J
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BU of 2q1j by Molmil
The discovery of glycine and related amino acid-based factor xa inhibitors
Descriptor: 1-(butyl{[(4-chlorophenyl)amino]carbonyl}amino)-N-[3-fluoro-2'-(methylsulfonyl)biphenyl-4-yl]cyclopropanecarboxamide, Activated factor Xa heavy chain (EC 3.4.21.6), CALCIUM ION, ...
Authors:Kohrt, J.T, Filipski, K.J, Cody, W.L, Bigge, C.F, Zhang, E, Finzel, B.C.
Deposit date:2007-05-24
Release date:2007-08-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:The Discovery of Glycine and Related Amino Acid-Based Factor Xa Inhibitors
BIOORG.MED.CHEM., 14, 2006
2NNQ
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BU of 2nnq by Molmil
Crystal structure of human adipocyte fatty acid binding protein in complex with ((2'-(5-ethyl-3,4-diphenyl-1H-pyrazol-1-yl)-3-biphenylyl)oxy)acetic acid
Descriptor: ((2'-(5-ETHYL-3,4-DIPHENYL-1H-PYRAZOL-1-YL)-3-BIPHENYLYL)OXY)ACETIC ACID, Fatty acid-binding protein, adipocyte, ...
Authors:Jacobson, B.L.
Deposit date:2006-10-24
Release date:2007-06-12
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Potent and selective biphenyl azole inhibitors of adipocyte fatty acid binding protein (aFABP).
Bioorg.Med.Chem.Lett., 17, 2007
1PZM
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BU of 1pzm by Molmil
Crystal structure of HGPRT-ase from Leishmania tarentolae in complex with GMP
Descriptor: GUANOSINE-5'-MONOPHOSPHATE, hypoxanthine-guanine phosphoribosyltransferase
Authors:Monzani, P.S, Trapani, S, Oliva, G, Thiemann, O.H.
Deposit date:2003-07-11
Release date:2004-07-27
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure of Leishmania tarentolae hypoxanthine-guanine phosphoribosyltransferase.
Bmc Struct.Biol., 7, 2007
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