1WDX
 
 | | Yeast BBC1 SH3 domain, triclinic crystal form | | Descriptor: | Myosin tail region-interacting protein MTI1 | | Authors: | Wilmanns, M, Consani Textor, L, Kursula, P, Kursula, I, Lehmann, F, Song, Y.H. | | Deposit date: | 2004-05-19 | | Release date: | 2005-05-31 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Crystal structure of Yeast BBC1 SH3 domain, triclinic crystal form
To be Published
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6ENZ
 | | Crystal structure of mouse GADL1 | | Descriptor: | Acidic amino acid decarboxylase GADL1, PYRIDOXAL-5'-PHOSPHATE | | Authors: | Raasakka, A, Mahootchi, E, Winge, I, Luan, W, Kursula, P, Haavik, J. | | Deposit date: | 2017-10-07 | | Release date: | 2018-01-03 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Structure of the mouse acidic amino acid decarboxylase GADL1.
Acta Crystallogr F Struct Biol Commun, 74, 2018
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2JKG
 | | Plasmodium falciparum profilin | | Descriptor: | MAGNESIUM ION, OCTAPROLINE PEPTIDE, PROFILIN | | Authors: | Kursula, I, Kursula, P, Ganter, M, Panjikar, S, Matuschewski, K, Schueler, H. | | Deposit date: | 2008-08-28 | | Release date: | 2008-09-23 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (1.89 Å) | | Cite: | Structural Basis for Parasite-Specific Functions of the Divergent Profilin of Plasmodium Falciparum.
Structure, 16, 2008
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2JKF
 | | Plasmodium falciparum profilin | | Descriptor: | PROFILIN | | Authors: | Kursula, I, Kursula, P, Ganter, M, Panjikar, S, Matuschewski, K, Schueler, H. | | Deposit date: | 2008-08-28 | | Release date: | 2008-09-23 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (2.31 Å) | | Cite: | Structural Basis for Parasite-Specific Functions of the Divergent Profilin of Plasmodium Falciparum
Structure, 16, 2008
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7A0H
 | | Structure of homodimeric actin capping protein alpha subunit from Plasmodium berghei | | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, BROMIDE ION, F-actin-capping protein subunit alpha, ... | | Authors: | Bendes, A.A, Kursula, P, Kursula, I. | | Deposit date: | 2020-08-09 | | Release date: | 2021-08-18 | | Last modified: | 2024-11-13 | | Method: | X-RAY DIFFRACTION (2.22 Å) | | Cite: | Structure and function of an atypical homodimeric actin capping protein from the malaria parasite.
Cell.Mol.Life Sci., 79, 2022
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7YWD
 | | Human GDAP1 core domain, trigonal crystal form | | Descriptor: | Ganglioside-induced differentiation-associated protein 1 | | Authors: | Raasakka, A, Kursula, P. | | Deposit date: | 2022-02-13 | | Release date: | 2022-06-08 | | Last modified: | 2024-11-13 | | Method: | X-RAY DIFFRACTION (3.2 Å) | | Cite: | Structural insights into Charcot-Marie-Tooth disease-linked mutations in human GDAP1.
Febs Open Bio, 12, 2022
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6EW4
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6EXJ
 | | PDZ domain from rat Shank3 bound to the C terminus of somatostatin receptor subtype 2 | | Descriptor: | SH3 and multiple ankyrin repeat domains protein 3, SSTR2 | | Authors: | Ponna, S.K, Keller, C, Ruskamo, S, Myllykoski, M, Boeckers, T.M, Kursula, P. | | Deposit date: | 2017-11-08 | | Release date: | 2018-03-07 | | Last modified: | 2024-11-06 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Structural basis for PDZ domain interactions in the post-synaptic density scaffolding protein Shank3.
J. Neurochem., 145, 2018
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6EW2
 | | Human myelin protein P2 F57A mutant, tetragonal crystal form | | Descriptor: | CHLORIDE ION, Myelin P2 protein, PALMITIC ACID | | Authors: | Laulumaa, S, Lehtimaki, M, Kursula, P. | | Deposit date: | 2017-11-03 | | Release date: | 2018-07-11 | | Last modified: | 2024-10-23 | | Method: | X-RAY DIFFRACTION (1.588 Å) | | Cite: | Structure and dynamics of a human myelin protein P2 portal region mutant indicate opening of the beta barrel in fatty acid binding proteins.
BMC Struct. Biol., 18, 2018
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6EW5
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2YPH
 | | Catalytic domain of mouse 2',3'-cyclic nucleotide 3'- phosphodiesterase, with mutation H230S, crystallized with 2',3-(RP)- cyclic-AMPS | | Descriptor: | 2', 3'-CYCLIC-NUCLEOTIDE 3'-PHOSPHODIESTERASE, ACETATE ION, ... | | Authors: | Myllykoski, M, Raasakka, A, Lehtimaki, M, Han, H, Kursula, P. | | Deposit date: | 2012-10-30 | | Release date: | 2013-07-10 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Crystallographic Analysis of the Reaction Cycle of 2',3'-Cyclic Nucleotide 3'-Phosphodiesterase, a Unique Member of the 2H Phosphoesterase Family
J.Mol.Biol., 425, 2013
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2YP0
 | | Catalytic domain of mouse 2',3'-cyclic nucleotide 3'- phosphodiesterase, crystallized with 2'-AMPS | | Descriptor: | 2', 3'-CYCLIC NUCLEOTIDE 3'-PHOSPHODIESTERASE, 2'-O-(sulfidophosphinato)adenosine, ... | | Authors: | Myllykoski, M, Raasakka, A, Lehtimaki, M, Han, H, Kursula, P. | | Deposit date: | 2012-10-29 | | Release date: | 2013-07-10 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Crystallographic Analysis of the Reaction Cycle of 2',3'-Cyclic Nucleotide 3'-Phosphodiesterase, a Unique Member of the 2H Phosphoesterase Family
J.Mol.Biol., 425, 2013
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2YPE
 | | Catalytic domain of mouse 2',3'-cyclic nucleotide 3'- phosphodiesterase, with mutation H309S, crystallized with 2',3'- cyclic AMP | | Descriptor: | 2', 3'-CYCLIC-NUCLEOTIDE 3'-PHOSPHODIESTERASE, 2',3'- cyclic AMP, ... | | Authors: | Myllykoski, M, Raasakka, A, Lehtimaki, M, Han, H, Kursula, P. | | Deposit date: | 2012-10-30 | | Release date: | 2013-07-10 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Crystallographic Analysis of the Reaction Cycle of 2',3'-Cyclic Nucleotide 3'-Phosphodiesterase, a Unique Member of the 2H Phosphoesterase Family
J.Mol.Biol., 425, 2013
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2YA9
 | | Crystal structure of the autoinhibited form of mouse DAPK2 | | Descriptor: | (4S,5S)-1,2-DITHIANE-4,5-DIOL, CALCIUM ION, DEATH-ASSOCIATED PROTEIN KINASE 2 | | Authors: | Patel, A.K, Kursula, P. | | Deposit date: | 2011-02-18 | | Release date: | 2011-04-13 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Structure of the Dimeric Autoinhibited Conformation of Dapk2, a Pro-Apoptotic Protein Kinase.
J.Mol.Biol., 409, 2011
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2YAB
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2YOZ
 | | Catalytic domain of mouse 2',3'-cyclic nucleotide 3'- phosphodiesterase, crystallized with 2'-AMPS | | Descriptor: | 2'-O-(sulfidophosphinato)adenosine, 2,3-CYCLIC NUCLEOTIDE 3'-PHOSPHODIESTERASE, ACETATE ION, ... | | Authors: | Myllykoski, M, Raasakka, A, Lehtimaki, M, Han, H, Kursula, P. | | Deposit date: | 2012-10-29 | | Release date: | 2013-07-10 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Crystallographic Analysis of the Reaction Cycle of 2',3'-Cyclic Nucleotide 3'-Phosphodiesterase, a Unique Member of the 2H Phosphoesterase Family
J.Mol.Biol., 425, 2013
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2YPC
 | | Catalytic domain of mouse 2',3'-cyclic nucleotide 3'- phosphodiesterase, with mutation H309S, crystallized with 2',3-(SP)-Cyclic-AMPS | | Descriptor: | 2', 3'-CYCLIC NUCLEOTIDE 3'-PHOSPHODIESTERASE, [(3aR,4R,6R,6aR)-4-(6-aminopurin-9-yl)-2-oxidanyl-2-sulfanylidene-3a,4,6,6a-tetrahydrofuro[3,4-d][1,3,2]dioxaphosphol-6-yl]methanol | | Authors: | Myllykoski, M, Raasakka, A, Lehtimaki, M, Han, H, Kursula, P. | | Deposit date: | 2012-10-30 | | Release date: | 2013-07-10 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (1.894 Å) | | Cite: | Crystallographic Analysis of the Reaction Cycle of 2',3'-Cyclic Nucleotide 3'-Phosphodiesterase, a Unique Member of the 2H Phosphoesterase Family
J.Mol.Biol., 425, 2013
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6GZL
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6GZJ
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4CN0
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4D6A
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8PI9
 | | DNA binding domain of HNF-1A bound to P2-HNF4A promoter DNA variant (P2 -181G>A) | | Descriptor: | Chains: E, Chains: F, Hepatocyte nuclear factor 1-alpha | | Authors: | Kind, L, Myllykoski, M, Raasakka, A, Kursula, P. | | Deposit date: | 2023-06-21 | | Release date: | 2024-06-19 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Molecular mechanism of HNF-1A-mediated HNF4A gene regulation and promoter-driven HNF4A-MODY diabetes.
JCI Insight, 9, 2024
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4D6B
 | | Human myelin protein P2, mutant P38G | | Descriptor: | MYELIN P2 PROTEIN, PALMITIC ACID, SULFATE ION | | Authors: | Laulumaa, S, Lehtimaki, M, Kursula, P. | | Deposit date: | 2014-11-10 | | Release date: | 2015-05-20 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (2.116 Å) | | Cite: | Dynamics of the Peripheral Membrane Protein P2 from Human Myelin Measured by Neutron Scattering-A Comparison between Wild-Type Protein and a Hinge Mutant.
Plos One, 10, 2015
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4D7C
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8PIA
 | | DNA binding domain of HNF-1A bound to P2-HNF4A promoter DNA variant (P2 -181G>T) | | Descriptor: | Chains: E, Chains: F, GLYCEROL, ... | | Authors: | Kind, L, Myllykoski, M, Raasakka, A, Kursula, P. | | Deposit date: | 2023-06-21 | | Release date: | 2024-06-19 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Molecular mechanism of HNF-1A-mediated HNF4A gene regulation and promoter-driven HNF4A-MODY diabetes.
JCI Insight, 9, 2024
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