2YPC

Catalytic domain of mouse 2',3'-cyclic nucleotide 3'- phosphodiesterase, with mutation H309S, crystallized with 2',3-(SP)-Cyclic-AMPS

Summary for 2YPC

• Entry DOI: 10.2210/pdb2ypc/pdb
• Related: 2XMI 2Y1P 2Y3X 2YDB 2YDC 2YDD 2YOZ 2YP0 2YPE 2YPH 2YQ9 3ZBR 3ZBS 3ZBZ
• Descriptor: 2', 3'-CYCLIC NUCLEOTIDE 3'-PHOSPHODIESTERASE, [(3aR,4R,6R,6aR)-4-(6-aminopurin-9-yl)-2-oxidanyl-2-sulfanylidene-3a,4,6,6a-tetrahydrofuro[3,4-d][1,3,2]dioxaphosphol-6-yl]methanol (3 entities in total)
• Functional Keywords: hydrolase, myelin, nervous system
• Biological source: Mus musculus (HOUSE MOUSE)
• Cellular location: Membrane ; Lipid-anchor : P16330
• Total number of polymer chains: 1
• Total formula weight: 24588.13

Authors

Myllykoski, M.,Raasakka, A.,Lehtimaki, M.,Han, H.,Kursula, P. (deposition date: 2012-10-30, release date: 2013-07-10, Last modification date: 2023-12-20)

• Primary citation: Myllykoski, M.,Raasakka, A.,Lehtimaki, M.,Han, H.,Kursula, I.,Kursula, P.; Crystallographic Analysis of the Reaction Cycle of 2',3'-Cyclic Nucleotide 3'-Phosphodiesterase, a Unique Member of the 2H Phosphoesterase Family; J.Mol.Biol., 425:4307-, 2013; PubMed: 23831225; DOI: 10.1016/J.JMB.2013.06.012

Experimental method

X-RAY DIFFRACTION (1.894 Å)